Tachysurus vachellii: 132844605
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Entry
132844605 CDS
T09596
Symbol
itcha
Name
(RefSeq) itchy E3 ubiquitin protein ligase a isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
tvc
Tachysurus vachellii
Pathway
tvc04120
Ubiquitin mediated proteolysis
tvc04144
Endocytosis
tvc04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
tvc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
132844605 (itcha)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
132844605 (itcha)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
132844605 (itcha)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tvc04131
]
132844605 (itcha)
04121 Ubiquitin system [BR:
tvc04121
]
132844605 (itcha)
Enzymes [BR:
tvc01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
132844605 (itcha)
Membrane trafficking [BR:
tvc04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
132844605 (itcha)
Ubiquitin system [BR:
tvc04121
]
Ubiquitin ligases (E3)
HECT type E3
132844605 (itcha)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
132844605
NCBI-ProteinID:
XP_060724209
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Position
4:19268983..19285817
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AA seq
847 aa
AA seq
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MKAQLQITVLSAKLKENKKNWFGPSPYVEVAVDGQSKKTEKCTNTLSPKWKQPLTVIVTP
FSKLIFRVWSHQTLKADLLLGMATLEVSETLKSNDMKIHEVIRTLPLSADAEGIDLVGDL
SVCLDGMRVDPETFASEEQRHNGLPNREFKLEATGRSSRDSSPSSDIADDSSLPNGHAVG
NTASPSTSTGALRPPRPPRPQRPPPPSPQRPNSSTASSTGSTPTHGSGGPSPDSSPRLFV
NGETASQGSTSGSALRVSPTPRRVSPINNGPLPHGWEQRVDQNGRIYYVDHIEKKTTWER
PEPLPPGWERRVDPMGRVYYVDHISRSTTWQQPTAESVRNYEEWQNQRSQLQGAMQQFNQ
RFIFGLQDQLAPAPNKEFDPLGPLPQGWEKRTDTNGRMYFVHHTTRSTQWEDPRTQGLLN
EKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSSLENGPQITYVRDFKAKVHYFR
FWCQQLAMPQHIKINVSRKTLFEDSFQQIMSFHPQDLRRRLWIIFPGEEGLDYGGVAREW
FFLLSHEVLNPMYCLFEYAGKDNYCLQINPASSINPDHLKYFKFIGRFIAMALFHGKFID
TGFSLPFYKRILNKPLALKDLESIDPEFYNSLIWIKENNLEECGLEMYFSVDKEILGEVT
THELKPDGGNVLVTEENKEEYIRLVAEWRLSRGVEEQTQAFFEGFNEVLPQQYLQYFDAK
ELEVMLCGMQEIDLSDWQRNTIYRHYARNSKQIMWFWQLVKEMDNEKRMRLLQFVTGTCR
LPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLMFAIEE
TEGFGQE
NT seq
2544 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcccagttacaaataacagttttgtcagctaagctgaaagagaacaagaagaac
tggtttgggcctagtccatatgtggaggtggctgtagatggccagtcaaagaaaacagag
aagtgcaccaacactctcagtccaaaatggaagcagccgctcacagtaattgttactcca
ttcagcaagttaatattccgtgtctggagtcatcagaccctcaaagcagaccttttgttg
ggaatggccactttagaagtcagtgagaccctcaaatccaatgacatgaagatccacgag
gtgatccggactctacctctgagtgcagatgcagagggcattgacttagtgggagatctg
tctgtgtgtctggatgggatgcgggtggatcctgaaacatttgcttctgaggaacagagg
cacaatggtctaccaaatagggagttcaagctagaagccactggaagatcgagtcgagat
tcgtcaccctccagtgacattgctgatgattcttctctgcccaatggtcatgctgtgggc
aacacagcttctccctcaacttccacaggagctctgcgacctccaaggcccccaagaccc
cagagaccacctcctccctctccacagagaccaaactcctccacagcatcctctactggc
tctacaccgacccatggcagtggtggtccaagtccagactcatccccacgcttatttgtg
aatggagaaacagcaagccagggttcgacctcagggtcagccctgagagtgagccccact
ccacgtagagtttctcccatcaacaatggcccacttcctcatggctgggaacagagggtg
gatcagaatggtcgtatatactatgtggatcacattgagaaaaagaccacatgggagcgg
cctgaacctttgcctcctggctgggagcgccgcgtggacccaatgggccgagtgtattat
gtggatcacattagtcggagcaccacatggcagcagcccactgcagagtctgtgaggaat
tatgaggaatggcagaaccaacgtagccagttacagggagccatgcagcagttcaaccag
agatttatttttgggttacaggatcaactagcgccagctcctaataaagagtttgatcca
ctgggtcctttaccacagggatgggagaagcgaactgatacaaatgggagaatgtacttt
gttcatcatactacgcgttcaacacagtgggaggatcctcgaactcaggggcttttaaat
gaaaagcccctgccagaaggttgggagatgaggttcacagtggacgggattccatatttt
gttgaccacaacaggagaacgaccacctacatcgaccctcgcacagggaaatcctcactt
gagaatggccctcagattacctatgtgcgtgactttaaagctaaagtgcactatttccgc
ttctggtgtcagcaactggcaatgcctcagcacatcaaaatcaacgtcagtcgcaagaca
ctttttgaggattcttttcagcagatcatgagcttccacccacaagatctgaggcggaga
ctatggatcatctttccaggagaggagggactggactatggaggcgtagctagggaatgg
tttttcctgttgtctcatgaagttctgaaccccatgtactgtctttttgagtatgcgggt
aaagacaactactgcctgcagatcaaccctgcgtcctccattaacccagaccacctcaaa
tatttcaagttcattggaagatttattgctatggctttgtttcatggaaaattcatagac
accggcttttctctgcccttctataagcggatcttgaacaagcctctggccctgaaagac
ctggaatccattgaccctgagttctacaactcactaatctggatcaaggagaataacttg
gaggagtgtgggctggagatgtatttctcagtggataaggagatcttgggtgaggtcacc
actcatgagctcaagccagatggaggaaacgttcttgttaccgaggaaaataaggaagag
tacatcagactggtggcagagtggagattatccaggggggtagaggaacagactcaagct
ttctttgaaggttttaacgaagtcttgcctcagcagtatctacagtattttgacgccaaa
gagctggaggtgatgctgtgtggaatgcaggagattgatctttcagactggcagaggaac
acaatctacagacattatgcccgcaacagcaagcagatcatgtggttctggcagcttgtg
aaagaaatggacaacgagaagaggatgcgattgttacagttcgtgaccgggacttgcagg
cttcctgttggagggtttgctgatctcatggggagcaatgggccacagaagttctgcatc
gagaaagtgggaaaagagaactggcttcccaggagccacacatgtttcaaccgtttggat
ctgcctccctataagagctatgagcagctcaaagaaaagttgatgtttgccatcgaggag
acagaaggctttggccaagagtga
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