Thermostichus vulcanus: NIES2134_122340
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Entry
NIES2134_122340 CDS
T05980
Symbol
shc
Name
(GenBank) squalene-hopene-cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
tvn
Thermostichus vulcanus
Pathway
tvn00909
Sesquiterpenoid and triterpenoid biosynthesis
tvn01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
tvn00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
NIES2134_122340 (shc)
Enzymes [BR:
tvn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
NIES2134_122340 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
NIES2134_122340 (shc)
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
TED_complement
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
BAY52692
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Position
2267399..2269327
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AA seq
642 aa
AA seq
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MSTSLATAIDPKQLQQAIRASQDFLFSQQYAEGYWWAELESNVTMTAEVILLHKIWGTEQ
RLPLAKAEQYLRNHQRDHGGWELFYGDGGDLSTSVEAYMGLRLLGVPETDPALVKARQFI
LARGGISKTRIFTKLHLALIGCYDWRGIPSLPPWIMLLPEGSPFTIYEMSSWARSSTVPL
LIVMDRKPVYGMDPPITLDELYSEGRANVVWELPRQGDWRDVFIGLDRVFKLFETLNIHP
LREQGLKAAEEWVLERQEASGDWGGIIPAMLNSLLALRALDYAVDDPIVQRGMAAVDRFA
IETETEYRVQPCVSPVWDTALVMRAMVDSGVAPDHPALVKAGEWLLSKQILDYGDWHIKN
KKGRPGGWAFEFENRFYPDVDDTAVVVMALHAVTLPNENLKRRAIERAVAWIASMQCRPG
GWAAFDVDNDQDWLNGIPYGDLKAMIDPNTADVTARVLEMVGRCQLAFDRVALDRALAYL
RNEQEPEGCWFGRWGVNYLYGTSGVLTALSLVAPRYDRWRIRRAAEWLMQCQNADGGWGE
TCWSYHDPSLKGKGDSTASQTAWAIIGLLAAGDATGDYATEAIEKGIAYLLETQRPDGTW
HEDYFTGTGFPCHFYLKYHYYQQHFPLTALGRYARWRNLLAT
NT seq
1929 nt
NT seq
+upstream
nt +downstream
nt
atgtcaacttcacttgcgacggccattgacccaaagcaactccaacaggcgattcgcgcc
agccaagactttctcttttcgcagcaatatgccgagggctactggtgggcggaattggag
tccaatgtaaccatgaccgcagaggtgatcctgctccacaaaatctggggcaccgaacag
cggttacccttggccaaggccgaacagtatttgcgcaaccatcagcgggatcacggcggt
tgggaactgttttatggcgatggtggtgatctcagcaccagtgttgaagcctacatggga
ttgcggctcttgggcgttcccgaaaccgatccagccttggtgaaggcacggcaatttatc
cttgcccgcggtggcattagcaaaacgcgcatctttaccaaactgcaccttgccctcatt
ggttgctatgactggcgggggattccctccctgcccccttggataatgcttctgccagag
gggagccccttcacgatttatgaaatgtccagttgggcccgtagcagcacggtgccgctg
ctaatcgttatggatcgcaagcctgtctatgggatggacccgcccattaccctcgatgaa
ctctacagcgaagggcgggcaaatgtggtctgggaactgcctcgccaaggcgactggcgt
gatgtttttattggcctcgatcgcgtcttcaaactctttgaaacgctgaacattcatccc
ctcagagaacaggggctcaaggctgccgaggaatgggtgctggagcgtcaagaagccagt
ggcgactggggcggcattattccggcaatgctcaactccctattggcgttgcgtgccctt
gactatgcggttgatgaccccattgtgcagcgggggatggcggcagtggatcgctttgcc
attgaaacggaaacggagtaccgcgtgcagccctgtgtctcccccgtttgggataccgcc
ttagtgatgcgagccatggtggattcaggggttgctcccgatcatcccgcccttgtcaaa
gctggcgaatggctactctccaagcaaatccttgactatggggactggcacatcaaaaac
aagaaaggtcggccgggcggatgggcctttgaatttgagaatcgcttctaccccgatgtg
gatgatacagcggtggtcgtgatggcgctccatgctgtgaccctacccaacgaaaaccta
aaacggcgagccattgagcgggcagtcgcttggattgcctcaatgcagtgtcggccaggg
ggttgggcggcctttgatgtggacaacgaccaagattggctcaatgggattccctacggc
gatctcaaggcaatgattgacccgaatactgctgatgttacggcacgagtgctggagatg
gtgggtcgctgtcagttggcctttgatagggttgccctcgatcgcgcccttgcttacctg
cgcaatgagcaggaaccggaaggctgttggtttggccgttggggggtgaactacctctat
ggtacgagcggggtgctgactgccctctcccttgtggctcctcgctacgatcgctggcgt
attcgccgtgctgctgagtggttgatgcagtgtcaaaatgccgatggtggctggggtgaa
acctgctggagctaccatgacccttcccttaagggcaaaggggatagcaccgcttcccaa
accgcttgggcgattattggccttttggccgctggcgatgccacgggggactacgccaca
gaggccattgaaaagggaattgcctatcttctcgagacgcagcgcccagatggcacatgg
cacgaggattacttcacgggcactggctttccctgccacttttacttgaagtaccactac
taccagcagcactttccgctgactgccttgggccgttatgcccgctggcgcaatctttta
gccacttag
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