Trichosurus vulpecula (common brushtail): 118841295
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Entry
118841295 CDS
T10126
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
tvp Trichosurus vulpecula (common brushtail)
Pathway
tvp04120
Ubiquitin mediated proteolysis
tvp04144
Endocytosis
tvp04330
Notch signaling pathway
tvp04668
TNF signaling pathway
tvp04932
Non-alcoholic fatty liver disease
Brite
Enzymes [BR:
tvp01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
118841295 (ITCH)
Membrane trafficking [BR:
tvp04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
118841295 (ITCH)
Ubiquitin system [BR:
tvp04121
]
Ubiquitin ligases (E3)
HECT type E3
118841295 (ITCH)
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Ortholog
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Gene cluster
GFIT
Other DBs
NCBI-GeneID:
118841295
NCBI-ProteinID:
XP_036604555
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Position
3:100576364..100736296
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AA seq
872 aa
AA seq
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MSGSSSRSGSVGGLTMKSQLQIIVISAKLKENKKNWFGPSPYVEVSVDGQSKKTEKCSNT
NSPKWKQPLTVIVTPVSKLNFRVWSHQTLKSDVLLGSAALDIHETLKANNMKLDEVVVTL
QLVGDKEPTEIIGDLSVCLDGLQVDPEILTNGYATCSEGSSQSDDSRTRNDTRPNTNGPD
NAEEPGPSENRKVNGNNSPSLTNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSAPSETPV
SSTESSPSTNMSVIPEGATAGASVPATVALTTPPTSRQVQSVNSASQQLNTVNQGPLPPG
WEQRVDQHGRVYYVDHIEKRTSWDRPEPLPPGWERRVDNMGRVYYVDHFTRTTTWQRPTL
ESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFTSTQNKEFDPLGPLPPGWEKRTDNN
GRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGVPYFVDHNRRTTTYIDPRT
GKSALDNGPQIAYVRDFKAKVHYFRFWCQQLSMPQHIKITVTRKTLFEDSFQQIMSFNPQ
DLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYIN
PDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWV
KENNIEECGLEMYFSVDKEILGEIKSHELKPNGSNILVTEENKEEYIRMVAEWRLSRGVE
EQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMW
FWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTC
FNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2619 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtagttcacggtcagggtctgtggggggattgaccatgaaatcacaactt
caaatcattgttatctcagcgaaacttaaagaaaataaaaagaactggtttggaccgagt
ccttatgtggaagtctcagtagatggacagtcaaagaagacagaaaaatgcagcaatacc
aacagtcccaaatggaagcagcctcttactgtaattgtcacacctgtcagcaaattaaat
tttcgtgtatggagtcaccagacattaaaatccgatgttttactgggaagtgctgctcta
gatattcatgagacgttaaaggcaaataatatgaaacttgatgaagtggttgtgacatta
caacttgtgggtgacaaggagccaacagaaatcataggagacttgtcagtttgtcttgat
ggattacaagtagatcctgagattctaacgaatggctatgccacatgttcagaaggtagt
tcacagagtgatgattccagaaccaggaatgatacaagaccaaatacaaatggacccgat
aatgctgaggaaccaggacccagtgaaaataggaaggtcaatggcaataactctccatcc
ctcacaaatggaggttttaaaccttctaggcctccaagaccttcacggccacctcctcct
actcctcgtagaccagcatctgtcaatggttctccatccgcaccttctgaaactcctgtg
tctagtacagagtcatcaccttcaacaaatatgagtgtaattcctgaaggagcaacagct
ggagcatcagttcctgccactgtggctttaacaacacctccaacctctagacaagtgcag
tcagtaaattctgcttctcagcagctcaatacagttaatcaaggtccccttccacctggt
tgggaacagagagtggaccagcatggacgcgtttactatgtagatcatattgaaaaaaga
acgtcatgggatagaccggaacctcttcctcctggctgggaacgtcgagttgacaacatg
ggacgtgtttattatgttgaccacttcacaagaactaccacctggcagcggccaactttg
gagtcagttagaaactatgagcagtggcaactacaacggagtcaactccaaggagcgatg
caacagtttaaccagagattcatttatgggaatcaagatttgtttacttcaactcagaat
aaagaatttgatcctcttggacctctgccaccaggatgggagaagagaacagataacaat
ggcagagtgtattttgtcaatcacaacacacgtatcacacagtgggaagatcccagaagt
caaggtcagttaaatgagaagcctttaccagaaggctgggaaatgagatttacagtggat
ggggttccatattttgtggatcataataggaggacaacaacatatatagatcctcgaact
ggaaaatctgctctagataatggaccccaaatagcctatgttagggatttcaaggcaaaa
gttcactacttccgtttctggtgtcagcaattgtctatgccacagcacatcaagattaca
gtgacaaggaaaactttgtttgaagattcatttcagcagataatgagtttcaatccccag
gatcttcgaagacgtttgtgggtgatttttccaggagaagaaggtttagattatggaggt
gtggcaagagaatggttctttcttttatcacatgaagtgctgaacccaatgtattgcctg
tttgaatatgcagggaaggataattactgcttgcagataaacccagcttcttatatcaat
ccagatcatctgaaatacttccgttttattggcaggtttattgccatggcattattccat
ggaaaattcatagatacaggcttttctttgccgttctataaacgtatcttgaataaacct
gttggactcaaggacttagaatctattgatccagaattttacaattctctcatctgggtt
aaagaaaacaatattgaagaatgtggtttagagatgtacttctcagttgataaggaaatt
cttggtgaaattaagagccatgaactgaaacccaatggcagtaatattctagtaacagaa
gaaaataaagaagaatacattagaatggtagctgaatggagattatctcggggtgttgaa
gagcagacacaagccttctttgaaggcttcaatgaaattcttccccagcagtacctgcaa
tactttgatgctaaggaactagaggtacttttgtgtggaatgcaagagattgatttaaat
gactggcaaagacatgccatctaccgacattatactaggacaagcaaacaaatcatgtgg
ttttggcagtttgtgaaagaaattgacaatgagaagagaatgagactgttgcagtttgtt
actgggacgtgcaggttgccagttgggggatttgctgacctcatggggagcaatggacca
caaaagttttgcattgaaaaagttgggaaagaaaattggttacctagaagtcatacctgc
tttaaccgcttggatctaccaccctacaagagctatgaacaactgaaggaaaaactgtta
tttgctattgaagaaacagaaggatttggacaagagtaa
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