KEGG   Thermoactinomyces vulgaris: AB849_006810
Entry
AB849_006810      CDS       T05864                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
tvu  Thermoactinomyces vulgaris
Pathway
tvu03030  DNA replication
tvu03410  Base excision repair
tvu03420  Nucleotide excision repair
tvu03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:tvu00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    AB849_006810 (ligA)
   03410 Base excision repair
    AB849_006810 (ligA)
   03420 Nucleotide excision repair
    AB849_006810 (ligA)
   03430 Mismatch repair
    AB849_006810 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tvu03032]
    AB849_006810 (ligA)
   03400 DNA repair and recombination proteins [BR:tvu03400]
    AB849_006810 (ligA)
Enzymes [BR:tvu01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     AB849_006810 (ligA)
DNA replication proteins [BR:tvu03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     AB849_006810 (ligA)
DNA repair and recombination proteins [BR:tvu03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     AB849_006810 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     AB849_006810 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     AB849_006810 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      AB849_006810 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 Nlig-Ia PTCB-BRCT HHH RNA_pol_A_CTD RNA_ligase Zn_ribbon_NUD Beta-prop_WDR35_TULP_N HNOB
Other DBs
NCBI-ProteinID: QBK13338
LinkDB
Position
1328815..1330884
AA seq 689 aa
MLPSRKNDEQEDEVGLKLEEAKKRVLELHDEINEHNHRYYVLDDPAISDAEYDRLMRELM
ALEKKFPELKTPDSPTQRVGGEPLPYFEKVEHTAPMLSLGNAFDEQDLRDFDERVRKAAG
RQNVRYVCELKIDGLAVSVKYEDGRFVLGSTRGDGITGEDITQNLKTIRSLPLRINEPLS
IEVRGEAYMPRRAFERLNRERAENGEPLFANPRNAAAGSLRQLDPKLAARRTLDLFVYEI
GQLEGHTVQTHTEGLQFLETLGFKVNPARQTVESVEEMLAFIEKWGKNRPDLPYEIDGIV
IKVDELALRKQMGNTAKSPRWAIAYKFPAEEAVTRLLDITLNVGRTGVVTPTAVLEPVSL
AGTTVQRASLHNEDLIREKDIRIHDYVVVKKAGDIIPEVVGVLTEKRTGGEKAFSMPEHC
PECGSGLVRLEGEVALRCINPECPAQTREGIIHFVSRGAMNIEGLGEKVVTQLFNHGLVR
SVADLYYLEKEDLLQLERMGEKSVQNLLEAIEKSKRNSLERLLFGLGIRFVGAKGAKILA
QHFKHMDALMEAGMEELLALDEIGPKMADSVVTYMEKPEVRETINRLKEAGVNMEYKGPG
ADGEKAVASSPLAGKTVVITGTLQKMSRKEATDLLESLGANVTGSVSKKTDLLVAGEKAG
SKLDKAKKLDVTIWDEETLLSHLPEEVRV
NT seq 2070 nt   +upstreamnt  +downstreamnt
atgctcccatcacgaaagaatgatgaacaggaggatgaagttggattgaagctggaagag
gcaaagaaacgcgtgctggaattgcatgatgaaatcaatgaacataaccaccggtattat
gttttggatgatccggccatttccgatgccgagtatgaccggttgatgcgcgagctcatg
gcattggaaaagaaatttcccgaactgaaaaccccggattcccccacccagcgggttggc
ggagaaccgcttccttattttgaaaaagtcgagcacaccgccccgatgctcagtttgggg
aacgcttttgacgagcaggatttgcgtgattttgacgagcgtgtgagaaaagcggccggc
cgccaaaatgtccgttatgtttgcgagttgaaaatcgacgggttggcggtttccgtcaaa
tatgaagacggccgttttgtcttgggatccacccggggagatggcatcaccggggaagat
atcacgcaaaacttaaaaacgatccggtccctgcctttgcgcatcaacgaaccgctttcc
atcgaagttcgcggggaagcgtacatgccgcggcgggcttttgaacgcttgaaccgggaa
cgggccgaaaacggggaacctttatttgccaacccgcgcaatgcggcagccggttcgctt
cgccagctggatcccaaattggcggcccggcggacgctggatttgtttgtttatgagatc
ggacaattggaaggccataccgtccaaacccacaccgaagggcttcaatttttggagacg
ttgggctttaaggtgaatccggcccggcagacggtggaatccgtggaggaaatgctggct
ttcattgaaaaatggggaaagaaccgcccggatcttccttacgagattgacggcattgtg
atcaaagtcgatgaattggcgttaagaaaacagatggggaacaccgccaaaagcccccgt
tgggccattgcctataaattcccggcggaagaagccgtcacccgtcttttggacatcacc
ctgaatgtcggtcggaccggcgtggtgacaccgactgccgttttggagccggtcagcctg
gccggaaccaccgtccaacgagcttctctgcataacgaagacttgatccgtgaaaaagat
atccggatccatgattatgtggtggtgaaaaaagcaggagacatcattccggaagtggtg
ggcgttctcaccgaaaagcgcaccggcggagaaaaagcgttttccatgccggaacactgt
ccggagtgtggcagcgggctggtccgccttgaaggtgaagtggcgcttcgctgcatcaat
cccgaatgtccggcgcagactcgggaaggcatcatccattttgtttcgcgtggtgcgatg
aatatcgaagggctgggcgaaaaagtggtgacccagctgtttaaccacggtttggtgcga
agcgtggcggatctttattaccttgaaaaagaagatttgttacagctggagagaatggga
gaaaaatcggtccaaaaccttctggaagccattgaaaaaagcaaacggaattcgctggaa
cggttgttgttcgggctggggatccgttttgtcggagccaaaggggccaaaattctggcg
caacacttcaagcatatggatgccctgatggaggcgggcatggaagaattgcttgccttg
gatgagatcgggccgaaaatggcagacagcgtggtcacctacatggaaaaaccggaagtc
cgggaaacgatcaatcgtttgaaagaagccggcgtgaatatggaatacaaagggccgggt
gcggatggagaaaaagccgttgcatcatcaccgttggccggaaagacggtcgtcatcaca
ggaacattgcagaagatgtcccgcaaagaggcaacggacctgctcgaatcgttgggggcc
aatgtcaccggaagcgtcagcaaaaagacggatttgttggttgccggcgaaaaagcgggc
tccaaactggacaaagcgaaaaaattggatgtgacgatttgggatgaagaaacgttgttg
agccatttgccggaagaagtgcgggtataa

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