Ursus arctos (brown bear): 113241174 Help Entry 113241174         CDS       T05909                                  Symbol IRS4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism uah  Ursus arctos (brown bear) Pathway uah04022   cGMP-PKG signaling pathway uah04068   FoxO signaling pathway uah04081   Hormone signaling uah04140   Autophagy - animal uah04152   AMPK signaling pathway uah04211   Longevity regulating pathway uah04213   Longevity regulating pathway - multiple species uah04910   Insulin signaling pathway uah04920   Adipocytokine signaling pathway uah04923   Regulation of lipolysis in adipocytes uah04930   Type II diabetes mellitus uah04935   Growth hormone synthesis, secretion and action uah05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:uah00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     113241174 (IRS4)    04022 cGMP-PKG signaling pathway     113241174 (IRS4)    04152 AMPK signaling pathway     113241174 (IRS4)   09133 Signaling molecules and interaction    04081 Hormone signaling     113241174 (IRS4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     113241174 (IRS4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     113241174 (IRS4)    04923 Regulation of lipolysis in adipocytes     113241174 (IRS4)    04920 Adipocytokine signaling pathway     113241174 (IRS4)    04935 Growth hormone synthesis, secretion and action     113241174 (IRS4)   09149 Aging    04211 Longevity regulating pathway     113241174 (IRS4)    04213 Longevity regulating pathway - multiple species     113241174 (IRS4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     113241174 (IRS4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     113241174 (IRS4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH_11 PH Motif Other DBs NCBI-GeneID:  113241174 NCBI-ProteinID:  XP_026334539 LinkDB All DBs Position X Genome browser AA seq 1327 aa AA seqDB search MASGSFARDQATRRLRAAAAATAAALAAVATTPLLSSGTPTALIGTGSSCPGAMWLSAAS GSRSDSESDEEDLPVGDEVCKRGYLRKQKHGHWRYFVLKLETADAPARLEYYENARKFRH SVRAAAAAAAAAASGASVPALIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV AENESEQESWYLLLSRLILESKRRRCGTPGAQPDGEPGALAAAAAAEPPFYKDVWQVIIK PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISVGAHLLTLLSTRRH LETLPREPGGWLRRSRFDQFYHLRAVGDGEDETLLTRRHITPSEPVPPSRRGRLHLPRAR RTRRAISAPASCFRRLPPSPVRVPHPAEVPSDRACLSPEASGSGNSGEEGSPQGQEGQEG NGGDYMPVNGWGSGNGQGSGGGQGSSGQGSSSQGSGGNQCSGGGQGSGGGGQGSGGGQGS SGGQGSGGGQGSSGGQGSRGQGAGGNQRSGDGQGTAGGHGSGSDQGAAGGGRGHGSGGGR GPGDGHGSGGGKNSGGAKGSGSGKTSDGNGERGKSLKKRSYFGKLTQSKQHMPPPPPLPP PPPTAGATGGKGKSGGRFRLYFCADRGAPKERKEAKEVKDLETPEGAAQGPHRARAFDED EDDPYMPMRPGVAAPLTSSSDYMPMAPQNFSASKRHSRSPFEDSRGYMMMFPTVSPPPVP SPPKEPDPEKEDESKDNDSESDYMFMAPGAGAIPKNPQNPQGGSSSKSWSSYFSLPNAFQ GSPLGQSEHSEYVPMLPGKVLGKGLDKEASSNGGPKDALSKPSAQGSFSKPGDGGSPSKP SDDGPPKNKAKRPNRLSFITKGSKIKPKSQKPTHEQRGAVSSSDYVNIDFTKRESNVPAP FIYGLPGSWGIIAGPRPSAFSNYVNIEFGLPFPNAAHRLSNLLRAIPGANPLYLEGARWP LAPLLRSATGGSASEEEGDYIEVIFNPAMTPIVPFGDSAIRYDAQTGRIYVVDPFSECCM DISLSPGRYSEPPPVARLLQEEQRLERRRPQSRSQSFFGSARAAVSAFPTDSLERDLSAP FASAAAASAAVPALALSRAVAAASASALAVAPGIGAAARGLDAAAGFDSASVRWFRPVAG AAASEAVRGAQNVAGGSNPRAPNPSADLAGGENGAAAAAPPPPPRRPVPSPPELEESDND DDDDDDETYVRMDFARPDYKKFDSPRRGYIARNLECSFPVTSSDRQVTFAVPHFLHVTSR KEGMVTT NT seq 3984 nt NT seq  +upstreamnt  +downstreamnt atggcgagtggctccttcgctcgcgaccaagcgacgaggagactgagagctgcagcagcg gcaacagcggcggctctagctgcggtagcgaccaccccacttctttcctcgggcaccccg accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccgcggcctct ggctcccggtccgactcggagtccgatgaggaggacctccccgtcggggacgaagtctgc aaacgcggctacctgcggaagcagaagcatgggcactggcgctacttcgtgctcaaactc gagaccgccgacgccccggctcggctggaatactacgaaaacgccaggaagttccggcac agtgtccgcgccgcggcagcggcggcggcggcggccgcctccggcgcctcggtccccgcg ctcatcccgccgcggcgcgtgatcaccctgtaccagtgcttctccgtgagccagcgggcc gatgcaaggtatcgacacctcatcgccctcttcacccaggacgagtacttcgcgatggtg gccgagaacgagtcggagcaggagagctggtacttgctgctcagccgcctcatcctcgag agcaagcgccgccgctgcggcacgccaggcgcgcagccggatggggagccgggcgcgctg gcggctgcagcggcggcggagccacccttctacaaagatgtgtggcaggtaataatcaaa cccagggggctggggcacagaaaagagctgagcggcgtgttccggctctgtcttaccgac gaggaggtggtatttgtgaggctgaataccgaagtggccagcgtggtcgtccagctcctg agcatccgtcgctgcgggcactcggagcagtatttcttcttggaagtgggtaggtccacc gtcatcggtcccggggagctctggatgcaggtcgatgactgtgtggtggcccaaaacatg cacgagctgtttctggagaagatgagagccctgtgcgcagacgagtaccgagcccgatgc cgcagctacagcatcagcgtcggcgcccacctgttaaccctgctgtccactaggaggcac ctggaaacgctgccgcgcgagcccggcggctggctgagaaggtcccgcttcgaccagttt taccacctcagggccgtcggtgatggggaagacgagacgctcctcaccaggcgccacata acacccagcgaacccgtgcccccctccaggcgaggaagactgcacctgcccagagcgcgc aggaccagaagagcgatttccgcgcccgccagctgttttcgccgcctaccacccagccca gtgcgcgtcccgcatcctgcagaagtcccgagtgacagagcttgcctgtctcctgaagct tctggctctggcaactctggggaagaaggcagtcctcagggccaagagggtcaggaagga aacggaggtgactacatgcccgtgaacggatgggggtcgggaaacggccagggttccgga ggtggccagggctcgagtggccaaggctccagtagccagggttcaggaggaaaccagtgc tctggcggggggcagggctccggaggaggcggccagggctccggtggcggtcagggctca agcggtggccagggctccggtggcggccagggctcaagcggtggccagggctcacggggc cagggtgcaggaggaaaccaacgttcaggagatggccagggcaccgcaggtgggcacggc tcgggcagtgaccagggagccgctggcggcggcaggggacatggctcaggcggtgggcgg ggacctggagatggccacggctcaggcgggggcaagaactctggaggggccaaaggctca ggaagtgggaaaacctccgatggcaatggtgaacgcggaaaatctctgaagaaaaggtcc tactttggcaaattaactcaaagcaagcagcacatgccaccaccaccacctcttccccct ccacccccaacagctggagcaactggcggtaaagggaagtctgggggaaggttccgactc tatttttgtgcggacaggggagccccaaaagaacgcaaagaggccaaggaggtcaaagac ttagagaccccagaaggtgcagctcagggtccccacagagccagagcttttgacgaagat gaggatgacccatacatgccaatgaggccaggggtggctgcgcctctcacaagctccagt gattatatgccaatggctcctcaaaacttctctgcttcaaaacgccactctcgatcacct tttgaagattcaagaggttacatgatgatgtttcccacagtgagcccaccacctgtccca agtcccccaaaagagccggatcctgaaaaggaggatgagtcaaaggacaatgacagtgag agtgactatatgtttatggctcctggagccggtgcaattccaaaaaacccccaaaatcct cagggtggctcttcctctaaaagttggagctcctacttttccctgccaaatgcttttcag ggctccccgttgggacagagtgagcacagtgagtatgtacccatgttacctggaaaagtc ctggggaagggcctagacaaggaagcctcatctaacgggggccccaaagatgcactttca aagccttcagcccaggggtcattctcaaagcctggagatggggggtcaccctcaaagcct tcagatgatgggcctcccaagaacaaggctaagagacctaaccgcctctctttcatcaca aaaggaagtaaaatcaagccaaaatcacaaaagcccacacatgagcagagaggagctgtc agctctagtgactacgtcaacattgacttcaccaagagagagagcaatgtgccagccccc tttatttacggactgccaggttcgtggggcatcattgctggacccagaccatccgccttt tccaactatgtgaatattgagttcggactgccatttccaaacgcagcacacaggctctcg aatcttttaagagccattccaggtgccaaccccctttatctggaaggtgctaggtggcca cttgcacctctacttcgcagcgctacaggtggcagtgcaagtgaggaagagggtgactat atcgaagtgattttcaatccagcaatgacaccgatcgtgccttttggtgacagtgccatc cgctatgatgctcaaacaggtcgcatctatgtggtcgacccgttttccgagtgctgtatg gacatttctctttcccccggccgctattccgaaccaccacctgtagccaggctgctgcag gaagaacagcggctagagcgaagacgcccgcaaagccgttcgcaaagtttctttgggtcc gccagggccgcggtctcggctttcccaaccgacagcctcgagagagacctctcggccccc tttgcctcggccgccgccgcctcggcagccgtgccagccttagccttgagccgggcggta gccgccgcctcggcctccgccctcgccgtggccccgggcatcggggcagccgccaggggc ttggatgccgccgcagggtttgactccgcctccgtccgctggttccgacctgttgctggc gccgcggcctccgaagcggtcaggggggcacaaaacgttgccggtggctcgaacccgaga gcccccaacccgtctgcagacctagccggaggtgagaacggggccgccgcggccgcgccc ccaccaccacctcgccgccctgtgccgagtccccccgagctcgaggagtctgacaacgac gacgacgacgacgacgacgaaacgtacgtgagaatggactttgccagacccgactacaag aagttcgactctccccgcagaggatacattgccagaaaccttgagtgttcctttcctgtc actagtagtgacaggcaagtcaccttcgctgtgcctcattttcttcatgtaacttcccgc aaagagggaatggtgacaacttga

DBGET integrated database retrieval system