Ursus arctos (brown bear): 113241452
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Entry
113241452 CDS
T05909
Symbol
EZH2
Name
(RefSeq) histone-lysine N-methyltransferase EZH2 isoform X2
KO
K11430
[histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:
2.1.1.356
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00310
Lysine degradation
uah01100
Metabolic pathways
uah03083
Polycomb repressive complex
uah05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
113241452 (EZH2)
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
113241452 (EZH2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
113241452 (EZH2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
uah03036
]
113241452 (EZH2)
Enzymes [BR:
uah01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase
113241452 (EZH2)
Chromosome and associated proteins [BR:
uah03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
113241452 (EZH2)
Polycomb repressive complex (PRC) and associated proteins
PRC2.1
113241452 (EZH2)
PRC2.2
113241452 (EZH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ezh2_MCSS
PRC2_HTH_1
SET
EZH2_WD-Binding
preSET_CXC
Motif
Other DBs
NCBI-GeneID:
113241452
NCBI-ProteinID:
XP_026334890
LinkDB
All DBs
Position
Unknown
AA seq
746 aa
AA seq
DB search
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF
MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ
YNDDDDDDDGDDPDEREEKQKDLEENRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL
KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH
ATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPN
NSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKM
KPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPA
PAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQ
NFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVS
CKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK
YMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGE
ELFFDYRYSQADALKYVGIEREMEIP
NT seq
2241 nt
NT seq
+upstream
nt +downstream
nt
atgggccagactgggaagaaatctgagaagggaccggtttgttggcgcaagcgtgtaaaa
tcagagtacatgcggctgcggcagctcaagcggttcaggcgggctgacgaagtgaagagt
atgtttagttccaatcgtcagaaaattttggaaagaacggaaatcttaaaccaagaatgg
aaacagcgaaggatacagcctgtgcacatcctgacttctgtgagctcattgcgcgggacc
agggagtgttcagtgaccagtgacttggattttccaacacaagtcatcccattaaagact
ctgaatgcggttgcttcagtccccataatgtattcgtggtctcccctacagcagaatttt
atggtggaagatgaaactgttttgcataacattccttacatgggggatgaagtcttagac
caggatgggactttcattgaagaactcataaaaaattatgatggaaaagtacatggggat
agagaatgtgggtttataaatgatgaaatttttgtggagttggtgaatgctcttggtcag
tacaatgatgatgatgatgatgatgatggagacgatcctgatgaaagagaagaaaaacag
aaagatctagaggagaacagagatgataaagaaagccgcccacctcggaaatttccttct
gataaaatttttgaagccatttcctcaatgtttccagataagggcacagcagaagaacta
aaggaaaagtataaagagctcaccgagcagcagctccccggcgcacttcctcctgaatgt
accccgaacatagacggaccaaatgctaaatctgttcagagggagcagagcttgcattca
tttcatacgcttttctgtaggcgatgttttaaatatgactgcttcctacatccttttcac
gcaacacccaatacttacaagcggaagaacaccgagacggctctagacaacaaaccttgt
ggaccacagtgttaccagcacttggagggagcgaaggagttcgctgccgcccttaccgcg
gagcggatcaagaccccgccgaagcggcccggcggccgcaggagaggcaggctccccaac
aacagcagccggcccagcacccccaccatcaacgtgctggagtccaaggacacagacagc
gacagggaagcgggcactgagacaggcggcgagaacaacgataaagaggaggaggagaaa
aaggacgagacttccagctcctcggaagcaaattctcggtgtcaaacgcccataaagatg
aagccaaacattgagcctcccgagaacgtggagtggagcggtgctgaggcctcgatgttc
agggtcctcattggcacgtattatgacaatttctgtgccattgccaggctcattgggacc
aaaacttgtcgacaggtgtatgagtttcgtgtcaaagaatcgagtatcatagctcccgct
ccggccgaggatgtggacacccccccgaggaagaagaagaggaaacaccggttgtgggct
gcacactgcagaaagatacagctgaaaaaggatggctcctcgaaccacgtttacaactac
caaccctgtgaccatccacggcagccttgtgacagttcgtgcccttgcgtgatcgcacaa
aatttttgtgaaaagttttgtcagtgtagttcagagtgtcagaaccgcttccccggctgc
cgctgcaaggcgcagtgcaacaccaagcagtgcccgtgctacctggccgtgcgcgagtgc
gaccccgacctctgcctcacctgcggcgccgccgaccactgggacagcaagaacgtgtcc
tgcaagaactgcagcatccagcgcggctccaagaagcatttattgctggcgccgtccgac
gtggcaggctggggcatcttcatcaaagaccccgtacagaagaatgaattcatctcggag
tactgtggagagattatttctcaagatgaagcagacagaagagggaaagtatatgataaa
tatatgtgcagctttctgttcaacttgaacaatgattttgtggtggatgcaacccgcaag
ggtaacaaaattcgttttgcaaatcattcagtaaatccgaactgctatgcaaaagttatg
atggttaacggcgatcacaggatagggatttttgctaagagagccatccagactggtgaa
gagctgttttttgattacagatacagccaggccgacgccctgaagtacgtgggcatcgaa
agagaaatggaaatcccttga
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integrated database retrieval system
