Ursus arctos (brown bear): 113243259
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Entry
113243259 CDS
T05909
Symbol
RYR1
Name
(RefSeq) ryanodine receptor 1
KO
K04961
ryanodine receptor 1
Organism
uah
Ursus arctos (brown bear)
Pathway
uah04020
Calcium signaling pathway
uah04371
Apelin signaling pathway
uah04713
Circadian entrainment
uah04730
Long-term depression
uah04921
Oxytocin signaling pathway
uah05017
Spinocerebellar ataxia
uah05020
Prion disease
uah05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
113243259 (RYR1)
04020 Calcium signaling pathway
113243259 (RYR1)
09150 Organismal Systems
09152 Endocrine system
04921 Oxytocin signaling pathway
113243259 (RYR1)
09156 Nervous system
04730 Long-term depression
113243259 (RYR1)
09159 Environmental adaptation
04713 Circadian entrainment
113243259 (RYR1)
09160 Human Diseases
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
113243259 (RYR1)
05020 Prion disease
113243259 (RYR1)
05022 Pathways of neurodegeneration - multiple diseases
113243259 (RYR1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
uah01009
]
113243259 (RYR1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
uah04147
]
113243259 (RYR1)
04040 Ion channels [BR:
uah04040
]
113243259 (RYR1)
Protein phosphatases and associated proteins [BR:
uah01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
113243259 (RYR1)
Exosome [BR:
uah04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
113243259 (RYR1)
Ion channels [BR:
uah04040
]
Voltage-gated cation channels
Ryanodine receptor
113243259 (RYR1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RYDR_Jsol
RYDR_ITPR
RyR
RR_TM4-6
SPRY
Ins145_P3_rec
MIR
RIH_assoc
Ion_trans
EF-hand_7
AIF_C
Motif
Other DBs
NCBI-GeneID:
113243259
NCBI-ProteinID:
XP_048079634
LinkDB
All DBs
Position
Unknown
AA seq
5036 aa
AA seq
DB search
MGDGGEGEDEVQFLRTDDEVVLQCNATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPP
DLAICCFVLEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHTHSGMYLSC
LTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYL
HLSTASGELQVDASFMQTLWNMNPICSGCEEGYVTGGHVLRLFHGHMDECLTISPADSED
QRRLVHYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLV
VVDSSKAHTKATSFCFRISKEKLDMAPKRDVDGMGPPEIKYGESLCFVQHVASGLWLTYA
APDPKALRLGVLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNQFIKGLDS
FSGKPRGSGPPAGTALPIEGVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQE
EGMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYELLASLIRGNRTNCALF
STNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVL
DVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGTTQYG
KWYFEVMVDEVAPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLH
LWTGHVARLVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPV
VSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLEPIKEYRREGPRGPHLV
GPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDN
KRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYM
MSNGYKPAPLDLSHVRLTPAQMTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPR
LVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSLVESQSRWDRVRIFRAEKS
YVVQSGRWYFEFEAVTTGEMRVGWARPDLRPDVELGADELAYVFNGHRGQRWHLGSEPFG
RPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVG
HLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEAVPLEHPHYEVTRV
DGTVDTPPCLRLSHRTWGSQNSLVEMIFLRLSLPVQFHQHFRCTAGATPLAPPGLQPPAE
DEARAAEPDPDYENLRRSAGRWGEPEGGKEGNAKEGAPGGNAQAGVEAQPVRVENEKDAT
TEKNKKRGFLFKAKKAAMMTQPPATPTLPRLPREVVPADNRDDPEIILNTTTYYYSVRVF
AGQEPSCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDF
VSSGHQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQN
VIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPISWSRMPNHFLQVETRRA
GERLGWAVQCQEPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYCAVCALGNNR
VAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTE
ETRAITLFPTGKSAENGSRRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGVAEAPARLS
PSIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFADEDV
KQILKMIEPEVFTEEEEEEEEEEEEEEDEEEKEEDEEEEAQEKEDEEKEEEETAEGEKEE
GLEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQANQRDRYGLL
IKAFTMSAAETARRTREFRSPPQEQINMLLQFKDGEDEEDCPLPEEVRQDLLEFHEDLLA
HCGIQLEGEEEEPEEEATLGSRLMSLLEKVRLVKKKEEKPEEEPPAEESKPQSLQELVSH
TVVHWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSMEDTMSLLECLG
QIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGGE
SKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAAS
VIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAV
FVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVRR
DRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRS
LVPLEDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLL
HVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMV
DSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKM
PLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDAELYRMA
MPCLCAIAGALPPDYVDASYSSKAEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFA
EYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAW
EWTIEKAREGEEEKTEKKKTRKISQSAQTYDPREGYNPQPPDLSGVTLSRELQAMAEQLA
ENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTR
GLKDMELDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFA
KILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGT
DAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQAR
TQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTK
NAYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEM
CPDIPVLERLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAG
APPPCTAVTSDHLNSLLGNILRIIVNNLGIDEATWMKRLAVFAQPIVSRARPELLHSHFI
PTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGEVLVRDEFSVLCRDLYALYPLLIRYVDNN
RAHWLTEPNPSAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKSKMA
KSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQELIAQAKNRYALKD
TDEEVREYLQNNLHLQGKVEGSPSLRWQMALYRGLPGREEDADDPEKIVRRVQEVSAVLY
HLEQIEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILT
EDHSFEDRMIADLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMA
YADIMAKSCHLEEGGENGEAEEEEVEVSFEEKEMEKQRLLYQQARLHNRGAAEMVLQMIS
ACKGETGAMVSSTLKLGISILNGGNADVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDL
NAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLR
TQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNS
LTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMV
VMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDP
RGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVA
VLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRTQ
WEMPQVKESKRQFIFDVVNEGGESEKMELFVSFCEDTIFEMQIAAQISEPEGEPEENEDD
GAAEAGVEGAEEGAAGPEGAAGPAAAGLTARAAAAAARALRGLSYRSLRRRVRRLRRLTA
REAAAAVAALLWAAVARAAGAGAGAAAGALRLLWGSLFGGGLVEGAKKVTVTELLAGMPD
PTGDEVHGEQPTGPGGDADGEGAGEGAGDEAEGAGDEEAAAHEAGPGGADGAAVVADGGP
FRPEGAGGLGDMGDTTPVEPPTPEGSPIIKRKLGVDGEEEELPPEPEPEPETEPEPEKAD
AENGEKEEVPEPPPEPPKKTAPPPPPPKKEEAGGGGSEFWGELEVQRVKFLNYLSRNFYT
LRFLALFLAFAINFILLFYKVSDSPPGEDDMEGSAAGDLSGVGSGGGSGWGSGAGEEAEG
DEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKL
EFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIYGRERIAELL
GMDLATLEITAHNERKPEPPPGLLTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLL
GHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRK
FYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFF
FFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLE
EHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS
NT seq
15111 nt
NT seq
+upstream
nt +downstream
nt
atgggtgacggaggagagggcgaggatgaggtccagtttctgcgcacggacgatgaagtg
gtccttcagtgcaatgccacggtgctcaaggagcagctgaagctctgcctggccgccgag
ggcttcggcaaccgcctctgcttcctggagcccaccagcaatgcccagaatgtgcccccc
gatctggccatctgttgcttcgtcctggagcagtccctgtcagtccgagccctgcaggag
atgctggccaacaccgtggaggctggcgtggagtcgtcccagggcgggggccacaggaca
ctcctgtacggccatgccatcctgctgcggcacacacacagcggcatgtacttgagctgc
cttaccacctcccgctccatgactgacaagctggccttcgacgtgggactgcaggaagat
gccacaggagaggcctgttggtggacgatgcacccggcctccaagcagaggtcggaagga
gagaaggtccgcgttggggatgacctcatcctcgttagtgtctcctcagagcgttacctg
cacctgtccacggccagtggggagctccaggttgatgcctccttcatgcagaccctgtgg
aatatgaaccccatctgctccggctgcgaagagggctacgtgaccgggggccacgtcctc
cgtctctttcacgggcacatggatgaatgtctgaccatttcccccgccgacagtgaggac
cagcgcagacttgtccactatgaagggggagctgtgtgtacccacgcccgctccctctgg
agactggagccactgagaatcagctggagtgggagccacctgcgctggggccagccactc
cgtatccggcacgtcaccactgggcggtacctggcactcactgaggaccagggcctggtg
gtggttgattccagcaaggcccacaccaaggccacctccttctgcttccgcatctccaag
gagaagctggatatggcccccaagcgggatgtggatggcatgggtccccctgagatcaag
tatggggagtcactgtgcttcgtgcagcacgtggcctcgggcctgtggctcacctatgct
gccccagaccccaaggccctgcggcttggtgtgctcaagaagaaggccatgctgcaccag
gaaggccacatggacgatgcactgtcactgacccgctgccagcaggaggagtcccaggcc
gcccgcatgatttacagcactgctggcctgtacaaccagttcatcaagggcctggacagc
ttcagcgggaagccgcggggctcggggccgccagctggtacagcgctgcccatcgagggt
gtcatcctgagcctgcaggacctcatcggctacttcgagccgccctccgaggagctgcag
cacgaggagaagcagagcaagctacgcagcctgcgcaaccgccagagcctcttccaggag
gaggggatgctctccttggtcctgaactgcattgaccgcctgaatgtctacaccactgct
gcccacttcgccgaatttgcgggggaggaggcagccgagtcttggaaagagattgtgaac
ctgctctatgaactcctggcctccctgatccgtggcaatcgtaccaactgtgccctcttc
tccaccaacctggactggctggtcagcaagttggatcggctggaggcctcctctgggatc
ctggaggtgctgtactgtgtcctgattgagagtcctgaggtgctgaacatcatccaagag
aaccacatcaagtccatcatctccctcctggacaagcacggaaggaaccacaaggtgcta
gatgtgctgtgttccctgtgtgtgtgcaatggcgtggccgtgcgctccaaccaagatctc
attactgagaacttgctccctggccgagagcttttgctgcagacaaacctcatcaactat
gtcaccagcatccgcccaaacatctttgtgggccgagcagagggcaccacgcagtatggc
aaatggtactttgaggtgatggtggacgaggtggctccattcctgacagctcaggccacc
cacctgcgggtgggctgggccctcactgagggctacagcccctacccagggggcggcgag
ggctggggcggcaatggggtcggcgacgacctctattcctacggctttgacgggctgcat
ctctggacaggacacgtggcacgcctggtgacttccccagggcagcacctcctggccccg
gaggacgtggtcagctgctgcctggacctcagtgtgccatccatctccttccgcatcaat
ggctgtcctgtgcagggcgtctttgaggccttcaacttggatgggctcttcttccctgtc
gtcagcttctcggctggtgtcaaggtgcggttcctgcttggtggtcgccatggtgaattc
aagttcctgcctccacctggctatgccccatgccacgaggctgtgctccctcgagagcga
cttcatctggagcccatcaaggagtatcggcgggaggggcctcgggggccccacctggtg
ggccccagccgctgcctctcacacaccgactttgtgccctgccctgtggacacggtccag
attgtcctgcctccccatctggagcgtattcgggagaagctggcagagaacatccacgaa
ctctgggcactgactcgcattgagcagggctggacctacggcccggttcgggatgacaac
aagaggctgcacccatgtcttgtggacttccacagcctaccagagcccgagaggaattac
aacctgcagatgtcgggggagacactcaagactctgctggcgctgggctgccacgtgggc
atggcggatgagaaggcggaagacaacctgaagaagaccaaactccccaagacgtacatg
atgagcaatgggtataagccggcaccgctagacctgagccacgtgcggctgacaccggcg
cagatgacgctggtggaccggctggcggagaatgggcacaatgtgtgggcacgagaccgc
gtggcccagggctggagctacagtgccgtgcaggacatcccagcacgccgcaaccctcgc
cttgtgccctaccgcctgctggatgaggccaccaaacggagcaaccgggacagcctctgc
caggccgtgcgcacgctgctgggctacggctacaacatcgagccgcctgaccaggagccc
agtctggtggagagccagtctcgctgggaccgggtgcgcatcttccgggcagagaaatcc
tatgtggtgcagagcggacgctggtactttgagttcgaagcagtcaccacgggtgagatg
cgagtgggctgggcgaggcccgacctgcggcctgacgtggagctgggagctgatgagctg
gcctatgtcttcaatgggcaccgcggccagcgctggcacttgggcagtgaaccatttggg
cgtccgtggcagccgggtgatgtcgtgggctgcatgatcgacctcacagagaacaccatt
atcttcaccctcaatggcgaggtcctcatgtctgattcgggctctgagacagccttccgg
gaaatcgagattggggatggcttcctgcctgtctgcagcttgggacctggccaggtgggt
cacctgaacctgggccaggacgtgagctccctgcggttctttgccatctgtggcctccag
gaaggctttgagccattcgccatcaacatgcagcgcccagtcaccacctggttcagcaaa
agccttccccaatttgaggccgtgccccttgagcacccccactatgaggtgacccgcgtg
gatggcaccgtggacacgccgccctgcctgcgcctgagccaccgcacctggggctcccag
aacagtcttgtggagatgatctttctccggctgagccttccagtccagtttcaccagcat
tttcggtgcaccgcaggggccacccccctggcgccccccggcctgcagccccccgccgag
gatgaagcccgggcggcggaacccgaccctgactacgaaaacctgcggcgctcagcgggg
cgctggggcgagcctgaggggggcaaagaaggaaatgccaaggagggggcgcccgggggc
aatgcccaggctggggtggaggcccagcctgtcagggtggagaacgagaaggatgccacc
acagagaagaacaagaagagagggtttttattcaaggccaagaaggccgccatgatgacc
caaccaccagccactcccactctgccccgactccctcgagaggtggtgcccgctgacaac
cgtgatgaccctgagatcatcctcaataccaccacgtactattactccgtgagggtcttc
gctggccaggagcccagctgtgtgtgggtgggctgggtcacccctgactaccatcagcac
gacatgaactttgacctcagcaaggtccgggcagtgactgtgaccatgggggacgaacaa
ggcaacgtccatagcagcctcaaatgcagcaactgctacatggtgtggggcggggacttc
gtgagctctgggcatcagggtcggatcagccacacagaccttgtcattggctgcctggtg
gacttggccactggcttgatgacctttaccgccaatggcaaagagagcaacacctttttc
caggtggagcccaacacgaagctgtttcctgccgtctttgtcctgcccacccaccagaac
gtcatccagtttgagttggggaaacagaagaacatcatgccgctgtccgccgccatgttt
ctgagtgagcgcaagaacccggccccgcagtgcccacctcggctagaggtgcagatgctg
atgcccatctcgtggagccgtatgcccaaccacttcctgcaggtggaaacgcgacgtgcg
ggcgagcggctcggctgggcggtgcagtgccaggagccgctgaccatgatggctttgcac
attcctgaggagaaccgatgcatggacattctggagctgtcggagcgcctggacctgcag
cggttccactctcacaccctccgcctctactgcgccgtgtgcgcgctgggcaacaaccgc
gtggcgcatgctctgtgcagccacgtggaccaggcgcagctgctgcacgcgctggaggac
gcgcacctgcccggcccgttgcgggccggctactacgacctcctcatcagcatacacctc
gaaagcgcctgccgcagccgccgctccatgctctccgagtacatcgtgcccctcacggag
gagacccgcgccatcactctcttcccgaccggaaaaagcgcggaaaatggctcccgccgc
cacggcctacctggcgttggcgtcaccacctcgctgcggcctccacaccatttctcacct
ccctgtttcgtggctgccctgccggctgctggcgtggcggaggctccggcccgcctcagc
cccagcatccccctggaggccctgcgggataaagcactgagaatgctgggagaggccgtg
cgagatggtgggcagcacgcacgtgaccccgtcgggggctctgtggagttccagtttgtg
cccgtgctcaagctcgtgtccaccctgctggtgatgggcatctttgccgatgaagatgtg
aaacagatcttgaagatgattgaacctgaagtattcactgaggaagaagaggaagaggaa
gaggaggaagaagaagaggaagatgaagaggagaaggaggaggatgaggaggaagaggca
caggagaaagaagatgaggaaaaagaggaagaggagacagcagaaggggaaaaagaagaa
ggcttggaggaagggctgctccagatgaagttgccggagtctgtgaagttacagatgtgc
cacctgctggagtatttctgtgaccaagagctgcagcaccgtgtggaatccctagcagcc
tttgcagagcgctacgtggacaaactccaggccaaccagagggaccgctatggcctcctc
ataaaagccttcaccatgtctgcagctgagactgcccgacgtactcgcgaattccgctcc
ccaccccaggagcagataaacatgctactgcagttcaaagatggtgaggatgaggaagat
tgtcctctccctgaagaggtccgacaggatttgctcgaatttcatgaagacttgctggca
cactgtggaattcagctggagggggaggaggaggaaccagaggaagaggccaccctgggc
agccgcctgatgagcctgttggagaaagtacggctggtgaagaagaaggaggagaaacct
gaggaggaaccacctgctgaggagagcaaaccccagtcattgcaagagctggtgtcccac
acagtggtgcattgggctcaagaggacttcgtgcagagccccgagcttgtacgggccatg
ttcagcctcctgcaccggcagtacgacgggcttggggagctgctgcgtgccctgccccgg
gcatacaccatctcaccatcatccatggaggacaccatgagcctgcttgagtgcctcggc
cagatccgatcactgcttatcgtgcagatgggtccccaggaggaaaacctcatgatccag
agcattgggaacatcatgaacaacaaagtcttctaccaacacccgaacttgatgcgagca
ctgggcatgcatgagacagtcatggaggtcatggtgaatgtcctcgggggtggtggtgaa
tccaaggagatccgcttccccaagatggtgacaagctgctgccgtttcctctgctacttc
tgtcgcatcagccggcagaaccaacgctccatgtttgaccacctgagctacctgctggag
aacagtggcatcggcctgggcatgcagggctccacgcctctggatgtggcagctgcttcc
gtcattgacaacaacgagctggccctggcattgcaagagcaggacctggagaaggtggtg
tcctacctggcgggttgtggccttcagagctgccccatgctcctggccaaagggtaccca
gacatcggctggaacccgtgtggtggtgagcgctacctggactttttacgcttcgctgtc
ttcgtcaacggtgagagcgtggaggagaacgccaacgtggtggtgaggctgctcatccgc
aagcccgagtgcttcgggcccgccctgcggggtgagggcggctcggggctgctggccgcc
atcgaagaggccattcgcatctctgaggacccggcgcgcgatggcccaggcgtccgcagg
gaccggcggcgtgagcactttggcgaagagcccccagaggagaaccgggtgcacctggga
cacgccatcatgtccttctacgctgccttgattgacctgctaggacgctgtgcaccagag
atgcacctaatccaagccggcaagggagaggccctgcggatccgcgccatcctgcgctcc
ctcgtgcccctggaagaccttgtgggcatcatcagcctccctctgcagatccccaccctg
ggcaaagatggggctctggtacagccaaagatgtcggcatccttcgtgccagaccacaag
gcatccatggtgctcttcctggaccgagtgtacggcattgagaaccaggacttcttgctg
catgtgctggacgtggggttcctgcctgacatgcgtgcagccgcttcgctggacacggcc
actttcagcaccacggagatggcgctggccctgaaccgctacctgtgcctggcggtgctg
ccgctcatcaccaagtgcgcgccgctcttcgcgggcaccgagcaccgcgccatcatggtg
gactccatgctgcacacggtgtaccgcctgtcccgcggccgctcgctcaccaaggcgcag
cgcgacgtcatcgaggactgtctcatggcactctgcaggtacatccgcccgtccatgctg
cagcacctgctgcggcgcctggtgttcgacgtgcccatcctgaacgagttcgccaagatg
ccgctcaagctcctcaccaaccactatgagcgctgctggaagtactactgcctccccacg
ggctgggctaacttcggggtcacctccgaggaagagctgcacctcactcgcaaactcttc
tggggcatctttgactcgctggcccataagaagtatgatgcagagctgtaccgcatggct
atgccttgtctgtgcgccatcgcaggggctctgccccctgactacgtggacgcctcgtac
tcatccaaggccgagaaaaaggccacggtggacgctgaaggcaactttgatcctcggcct
gtggagaccctcaatgtgatcatcccagagaagctggactccttcattaataagtttgca
gagtacacgcatgagaagtgggccttcgacaagatccagaacaactggtcctatggggag
aacatagatgaggaactgaagacccatcccatgctgaggccctataagaccttttcagag
aaggataaagagatttaccgctggcccatcaaggagtccttgaaggccatgattgcctgg
gaatggacgatagagaaggccagggagggcgaggaggagaagacagagaagaagaaaact
cggaagatatcccaaagtgcccagacttatgatccgcgagaaggctacaacccccagccc
cccgacctcagcggagttaccctgtcccgggagctgcaggccatggcagaacaactggca
gaaaattaccacaacacgtgggggcggaagaagaagcaggagctggaggccaaaggtggt
gggacccaccccctgctggtcccctatgacacacttacagccaaggagaaagcccgagat
cgagagaaggcccaagagctgctgaagttcttgcagatgaacggctatgctgtcaccaga
ggccttaaggacatggagctggacacgtcttccattgagaaacggttcgcctttggcttc
ctgcagcagttgctgcgctggatggacatttcccaggagtttatcgcccacctggaggct
gtggtcagcagtggacgagtggaaaagtccccacacgaacaggagattaaattctttgcc
aagatcctgctccctttgatcaaccagtacttcaccaaccactgcctctatttcctgtcc
acaccagccaaagtgctgggcagtggcggccatgcctccaacaaggagaaggaaatgatc
accagcctcttctgcaagcttgctgctcttgtccgtcaccgagtttctctctttggcaca
gatgctccagctgtggttaattgtcttcacatcctggcccgctccctggatgccaggacg
gtgatgaagtcaggccctgagatcgtgaaggctggcctccgctccttcttcgagagcgca
tcagaggacattgagaagatggtggagaacctgcgcctaggcaaggtgtcccaggcgcgc
acacaggtgaagggcgtgggccagaacctcacctacaccaccgtggccctgctgcctgtc
ctcaccacgctcttccagcacatcgcccagcaccagttcggagacgacgttatcctggat
gatgtccaggtctcttgctaccgaacgctgtgcagtatctactctctgggaaccaccaag
aacgcttacgtggaaaagttgcggccggccctaggggagtgcttggctcgcctggcagca
gctatgccggtggcgttcctggagccccagctgaacgagtacaacgcctgctcggtgtac
actaccaagtctccccgggaacgggccatcctggggctccccaacagcgtggaggagatg
tgtcctgacatcccggtgctggagcggctcatggcagacatcggggggctggctgagtcg
ggggcccgctacacggagatgccgcacgtcatcgagatcacactacccatgctgtgcagt
tacctgccccgctggtgggaacgcgggcccgaggcccccccgcctgccctgcccgctggg
gcccccccgccctgcacggctgtcacctcggaccacctcaactcgctgctgggcaatatc
ctgcgaatcatcgtcaacaacctgggcattgacgaggcgacgtggatgaagcggctcgct
gtgttcgcccagcccatcgtgagccgggcccggcctgagctcctgcattcacacttcatc
cccaccatcgggcgcctgcgcaagcgggcagggaaggtggtggccgaggaggagcagctg
cgcctggaggccaaggccgaggccgaggagggcgaggtcctggtgagggacgagttctct
gtgctctgcagggacctgtacgccctctacccgctgctcatccgctacgtggacaacaac
agggcacactggctgaccgagcccaatcccagcgccgaggaactgttcaggatggtgggt
gagatcttcatctactggtccaagtcccacaactttaagcgcgaggagcagaactttgtg
gtccagaatgagatcaacaacatgtcatttctgactgctgacaacaagagcaaaatggcc
aagtcaggcggctcggaccaggagcgcaccaagaagaagcgccgcggggaccggtactct
gtacagacgtccctgattgtggccacgctcaagaagatgctgcccatcggcctgaacatg
tgtgcacccacggaccaggaactcatcgcgcaggccaagaaccgctatgccctgaaagac
acagacgaggaggtccgggaatatctgcaaaacaaccttcacctccagggaaaggttgaa
ggctccccttctttgcgctggcagatggccctgtaccggggcctcccgggccgcgaggag
gacgccgatgaccccgagaaaatcgtgcgcagagtccaggaagtgtctgcggtgctctac
cacctggagcagattgagcacccctacaaatccaagaaggccgtgtggcacaagctcctg
tccaagcagcgccgcagggcggtggttgcctgtttccgcatgacccccctgtacaacctg
cccacgcacagggcctgtaacatgttcctggagagctacaaggccgcgtggatcctgact
gaagaccacagttttgaagaccgcatgatcgccgacctttcaaaagctggggagcaggag
gaggaggaggaggaggtggaggaaaagaagcctgaccccctgcatcagctggtcctgcac
ttcagccgcacggccctgactgaaaagagcaaactggacgaggattacctgtacatggcg
tatgccgacatcatggcaaagagctgccacctggaggagggaggggagaatggcgaagct
gaagaggaggaagtggaggtttcctttgaggagaaagagatggagaagcagaggctcctg
tatcagcaggcgcggctgcacaaccggggagccgccgagatggtgctccagatgatcagc
gcctgcaaaggagagacgggcgccatggtgtcctccaccttgaagctgggcatctccatc
ctcaatggaggcaatgcggacgtgcagcagaaaatgctggattatctgaaggacaagaag
gaagtgggcttcttccagagtatccaggcactgatgcagacgtgcagcgtcctggatctc
aacgccttcgagagacagaacaaggcagaggggctgggcatggtgaacgaagatggaact
gtcatcaaccgccagaacggagagaaggtcatggcagatgatgaattcacccaagacctg
ttccgattcctacaattgctctgcgaggggcacaataatgatttccaaaactacctacgg
acacaaacagggaacacaaccaccattaacatcatcatctgcacggtggactaccttctg
cggctgcaggagtccatcagcgacttctactggtactactccggcaaggatgtcattgag
gagcagggcaagaggaacttttccaaggctatgtcggtcgctaaacaggtgttcaacagc
ctcaccgagtacatccagggcccctgcaccgggaaccagcagagcctggcgcacagccgc
ctctgggacgccgtggtgggattcctgcacgtgtttgcccacatgatgatgaagctcgct
caggactccagccagatcgagctgctgaaggaactgctggacctacagaaggacatggtg
gtgatgttgctgtcgctactagaagggaacgtggtgaacggcatgattgcccggcagatg
gtagacatgctcgtggaatcctcatccaacgtggagatgatccttaagttcttcgacatg
ttcctgaaactcaaggacattgtgggctcggaggccttccaggactacgtcactgatccc
cgtggcctcatctccaagaaggacttccagaaggctatggacagccagaagcagttcaca
ggcccagaaatccagttcctgctttcctgctccgaagcagatgagaacgagatgatcaac
tgtgaggagttcgccaaccgcttccaggagccagcccgcgacatcggcttcaacgtggca
gtgctgcttaccaatctgtcggagcacgtgccccacgacccgcgcctgcgcaacttcctc
gagctggcggagagtatcctcgagtacttccggccctacctgggccgcatcgagatcatg
ggtgcctcgcgccgcatcgagcgcatctacttcgagatctcggagaccaaccgcacccag
tgggagatgccccaggtcaaggagtccaagcggcagttcatcttcgacgtggtgaacgag
ggcggcgagtccgagaagatggagctcttcgtgagcttctgcgaggacaccatcttcgag
atgcagatcgccgcgcagatctccgagcccgagggcgagccggaggagaacgaggacgac
ggcgctgccgaggcgggcgtcgagggcgcggaggagggcgcagcggggcccgagggcgcg
gcggggccggcggcggcgggtttgacggcgcgcgcggcggcggcggcggcgcgggcgctg
cgcggcctcagctaccgcagtctgcggcggcgcgtgcggcggctgcggcggctcacggcg
cgcgaggcggccgcggcggtggcggcgctgctctgggcggcggtggcgcgcgcggcgggc
gcgggcgcgggcgcggcggcaggcgcgctgcgcctgctctggggctcgctcttcggcggc
ggcctcgtggagggcgccaagaaggtgacggtgaccgagctcctggccggcatgcccgac
cccacgggcgacgaggtgcatggcgagcagcccaccgggcccggcggcgacgcggacggc
gagggcgcgggcgagggcgcgggcgacgaggcggagggcgcgggcgacgaggaggcggcg
gcgcacgaggccggcccgggaggagccgacggggccgctgtcgtggcggacgggggcccc
ttccggcccgaaggggcgggcggcctcggggacatgggtgacacgacgccggtggagccg
cccacgcccgagggttcccccatcatcaagaggaagctgggggtggatggagaggaagag
gagctgcctccagaaccagagcctgagccagagacagagcccgagcccgagaaagccgat
gctgagaatggggagaaggaagaagtccccgaacccccaccagagccccccaagaagaca
gcacctcctccaccccctccaaagaaggaggaggctggaggcgggggctcagaattctgg
ggagaactggaagtgcagagggtgaagttcttgaactacctgtcccggaacttctacacc
ctgcggttccttgccctcttcttggcctttgccatcaacttcatcctgctgttttataag
gtctcagactctccaccaggggaggacgacatggagggctcagcagccggggacctgtca
ggtgtggggtctggtggcggctctggctggggctcgggggccggcgaggaagcggagggc
gacgaggacgagaacatggtgtactacttcctggaggagagcacgggctacatggagcct
gccttgcgttgcttgagcctgctgcatacgctggtggccttcctctgcatcatcggctac
aactgcctcaaggtgcccctggtgatctttaaacgggagaaggagctggcccggaagctg
gagtttgacggcctctacatcacggagcagcctgaggatgacgatgtgaagggccagtgg
gaccggctggtgctcaacacgccgtctttccccagcaactactgggacaagtttgtcaag
cgaaaggtcctggacaagcatggagacatctatgggcgggagcggatcgccgagctgctg
ggcatggatctggccaccctggagatcacagcccacaatgagcgaaagcccgaaccacca
ccggggctgcttacctggctcatgtccattgacgtcaagtaccagatctggaagttcggg
gtcatcttcacagacaattctttcctgtacctgggctggtacatggtgatgtccctcctg
ggacactacaacaacttcttctttgctgcccacctcctggacatcgccatgggggtcaag
acgctgcgcaccatcctctcctccgtcacccataatgggaagcagctggtgatgaccgtg
ggcctcctggcggtggtggtctacctgtacaccgtggtggccttcaacttcttccgcaag
ttctacaacaagagtgaggatgaggacgagcctgacatgaagtgtgacgacatgatgacg
tgttacctgtttcacatgtatgtgggtgtccgagctggtgggggcatcggggatgagatt
gaggacccagcaggcgatgaatacgagctgtaccgagtggtcttcgacatcaccttcttc
ttctttgtcatcgtcattctgctggccatcatccagggtctgatcattgatgcttttggc
gagctccgagaccaacaagagcaagtgaaggaagatatggagaccaagtgcttcatctgc
ggcatcggcagtgattactttgatacgacgccgcacgggttcgagacccacacgctagag
gagcacaacctggccaattacatgtttttcctgatgtatctgataaataaggacgagaca
gaacacacgggccaggagtcttatgtctggaagatgtaccaagagagatgttgggatttc
ttcccagctggcgattgtttccgcaagcagtacgaggaccagcttagctga
DBGET
integrated database retrieval system
