Ursus arctos (brown bear): 113243430 Help Entry 113243430         CDS       T05909                                  Symbol HK2 Name (RefSeq) hexokinase-2   KO K00844   hexokinase [EC:2.7.1.1] Organism uah  Ursus arctos (brown bear) Pathway uah00010   Glycolysis / Gluconeogenesis uah00051   Fructose and mannose metabolism uah00052   Galactose metabolism uah00500   Starch and sucrose metabolism uah00520   Amino sugar and nucleotide sugar metabolism uah00524   Neomycin, kanamycin and gentamicin biosynthesis uah01100   Metabolic pathways uah01200   Carbon metabolism uah01250   Biosynthesis of nucleotide sugars uah04066   HIF-1 signaling pathway uah04910   Insulin signaling pathway uah04930   Type II diabetes mellitus uah04973   Carbohydrate digestion and absorption uah05230   Central carbon metabolism in cancer Module uah_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate uah_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc uah_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:uah00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     113243430 (HK2)    00051 Fructose and mannose metabolism     113243430 (HK2)    00052 Galactose metabolism     113243430 (HK2)    00500 Starch and sucrose metabolism     113243430 (HK2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     113243430 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     113243430 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     113243430 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     113243430 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     113243430 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     113243430 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     113243430 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uah04131]     113243430 (HK2) Enzymes [BR:uah01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      113243430 (HK2) Membrane trafficking [BR:uah04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     113243430 (HK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  113243430 NCBI-ProteinID:  XP_026337844 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDENLLEISKRFRKEMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDLMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCVQTKLDESFLVSWTKGFKSSGV EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGTLDDFRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKVSPGLLTTGQFETKDVSDIEGEKDGTRKAREVLVRLG MDPTQEDCVATHRICQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH PHFAKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQNTLESLKLS REQLLEVKRRMNVEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD FRTEFDVAVDELSLNPGRQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILRHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgcctcgcatctgctcgcctacttcttcacggagctcaaccatgaccaagtgcag aaggtcgaccagtatctctaccacatgcgtctttctgatgagaaccttctggagatctct aagcggttccgcaaggagatggagaaagggcttggagccaccacccaccccactgcttca gtgaaaatgctgcccacctttgtgaggtctactccagatgggacagaacacggagagttt ctggctctggacctcggagggacaaacttccgtgtacttcgggtaagagtaacggacaat gggctccagaaggtggagatggagaaccagatctatgccatccccgaggacctcatgcgg ggcagcggcacccagctgtttgaccacattgcggaatgcctggctaacttcatggataag ctacaaatcaaagacaagaagctccccttgggttttactttctcattcccctgcgtccaa acgaaactagatgagagtttcctggtctcctggaccaaggggttcaagtccagtggtgtg gaaggcaaagacgtggttactctgatccgaaaggccatccagaggagaggggactttgat attgatattgtggccgtggtgaatgacacagttgggaccatgatgacctgtggttatgat gaccagaattgcgagattggtctcattgtaggcacgggcagcaatgcctgctacatggaa gagatgcgccacattgacatggtggagggagacgaggggcggatgtgtatcaatatggag tggggggccttcggggacgacggcacgctcgatgacttccgcaccgagtttgatcaggag atcgacatgggctccctgaaccccgggaagcaactatttgagaagatgatcagtgggatg tacatgggagaactggtgaggcttatcctggtgaagatggccaaggaagagctgctcttt ggggggaaggtcagcccagggctccttaccactggccagtttgagaccaaagacgtttca gacattgaaggggagaaggacggcacccggaaggcgcgtgaggtgctggtgcggctgggc atggacccgacacaggaggactgcgtggccactcaccggatctgccagatcgtgtctacg cgctcagccagcctgtgcgcggccaccctggcggccgtgctgcggcgcatcaaggagaac aagggcgaggagcggctgcgctccaccattggggtggatggctctgtctacaagaagcac ccacactttgccaagcgtcttcacaaggccgtccggcgcctggtgcccgactgcgacgtc cgcttcctgcgttccgaggatggcagcggcaagggggcggccatggtgacggcggtggcc taccggctggccgaccaacaccgggcccgccagaacaccctggagtctctgaagctgagc cgcgagcagctgctggaggtcaagaggaggatgaacgtggaaatggagcgaggtctgagc aaggagactcacgccattgcccccgtcaagatgctgcccacctacgtgtgcgccacgcct gacggcacagagaagggtgacttcctggccttggaccttgggggtaccaacttccgggtc ctgctggtgcgcgtgaggaacggaaagcggcgtggagtggagatgcacaacaagatctac tctatcccgcaggaggtcatgcacggcacaggggatgagctctttgaccacatcgtccag tgcatcgctgacttccttgagtacatgggcatgaagggcgtgtccctgcccctgggtttc accttctccttcccctgccagcagaacagcctggatgagagcatcctcctcaagtggacc aaaggcttcaaggcatcgggctgcgagggagaggacgtggtcacgctgctgaaggaggcc atccaccggcgagaggagtttgacctggacgtggttgccgtggtgaatgacacggtcggg actatgatgacctgtggctatgaagaccctcactgtgaagttggcctcatcgttggcaca ggcagcaacgcctgctacatggaggagatgcggaatgtggagctggtggagggggaagag ggccggatgtgtgtcaacatggagtggggggccttcggggacaacggatgcctcgatgac ttccgcacggaatttgatgtggctgtggatgagctttccctcaaccctggcagacagagg ttcgagaaaatgatcagtggcatgtacttgggtgagattgtccgtaacatcctcatcgat ttcaccaagcgtgggctgctcttccgtggccgcatctcagagcggctcaagacaagagga atctttgaaaccaagttcctgtctcagattgagagtgactgcctggccctgctgcaggtg cgcgccatcctgcgccacctggggctcgagagcacctgtgacgacagcatcattgtcaaa gaggtgtgcaccgtggtggcgcggcgggcggcccagctctgtggtgcgggcatggccgcc gtggtggacaagatacgagaaaaccgggggctggacaccctcaaagtgaccgtgggcgtg gatgggaccctctacaagctacatccccactttgccaaagtcatgcacgagacggtgaag gacttggctccgaaatgtgacgtgtccttcctggagtcagaggacggcagcgggaagggg gcggctctcatcactgctgtggcctgccgcatccgcgaggctggccagcgatag

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