Ursus arctos (brown bear): 113244597 Help Entry 113244597         CDS       T05909                                  Symbol SPHK1 Name (RefSeq) sphingosine kinase 1 isoform X1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism uah  Ursus arctos (brown bear) Pathway uah00600   Sphingolipid metabolism uah01100   Metabolic pathways uah04020   Calcium signaling pathway uah04071   Sphingolipid signaling pathway uah04072   Phospholipase D signaling pathway uah04148   Efferocytosis uah04370   VEGF signaling pathway uah04371   Apelin signaling pathway uah04666   Fc gamma R-mediated phagosome formation uah05152   Tuberculosis Module uah_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:uah00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     113244597 (SPHK1)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     113244597 (SPHK1)    04371 Apelin signaling pathway     113244597 (SPHK1)    04020 Calcium signaling pathway     113244597 (SPHK1)    04072 Phospholipase D signaling pathway     113244597 (SPHK1)    04071 Sphingolipid signaling pathway     113244597 (SPHK1)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     113244597 (SPHK1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagosome formation     113244597 (SPHK1)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     113244597 (SPHK1) Enzymes [BR:uah01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      113244597 (SPHK1) SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  113244597 NCBI-ProteinID:  XP_026339870 LinkDB All DBs Position Unknown AA seq 487 aa AA seqDB search MPERAGRRAWSEDLAGRSPPQGAAPDSASAVSSPSDPAAAGDDAGASTAPAPGGEGEPLS RHRDARLGSTDKELKAGAAAAGSSATALGTPWQRELRVEVMDPAGGARSLLPRPCRVLVL LNPRGGKGKALQLFRSHVQPLLVQADVSFTLMLTERRNHARELVRVEELGRWDALVVMSG DGLMHEVVNGLMERPDWETAIRKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTL LLCRRLLAPMNLLSLRTASGLRLFSVLSLAWGFIADVDLESEKFRRLGEMRFTLGTFLRL AALRVYQGTLAYLPAERVVSQVPAPPAVERQDQQGPTDAHLVPLEEPVPPHWTVVPEQDF VLVLALLHSHLGSEMFAAPMGRCAAGTMHLFYVRAGVSRAMLLRLFLAMEKGRHMDYDCP YLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPDYVWMVSGCMEPPPSQKPQQG PPPGEPL NT seq 1464 nt NT seq  +upstreamnt  +downstreamnt atgcccgagcgcgcgggtcgtcgcgcgtggtccgaggatctagctgggcgctccccacct cagggggccgctccggactccgccagcgctgtctcctctccctcagatcccgcagccgca ggggatgacgcgggtgcctccacggccccggctccgggcggggagggcgagcccctcagc cggcaccgcgacgcccgcctgggcagcaccgataaggagctgaaagcaggagccgccgcc gcgggcagctccgcgacagcgctggggacgccctggcagcgggagctgcgagtcgaggtt atggatccagcgggcggcgccaggagcctgctgccccggccctgccgcgtgctggtcctg ttaaacccgcgcggaggcaagggcaaggcgctgcagctcttccgcagccacgtgcagcct ctgctggtccaagccgatgtctccttcacgctcatgctaactgagcggcggaaccatgca cgggagctggtgcgggttgaggagctggggcgctgggatgcgctggtggtcatgtctgga gacgggctgatgcatgaggtggtgaacgggctcatggagcggccagactgggagactgcc atccgaaagcccctgtgtagcctcccagctggctctggcaatgcactggcagcttctttg aaccattatgctggctacgagcaggtgactaatgaggacctcctgaccaactgcacgctg ctgctgtgtcgccgcctcctggcgcccatgaacctgctgtcactgaggacagcctcaggg ctgcgcctcttctccgtgctgagcctggcttggggcttcatcgccgacgtggatctggag agtgagaagtttcggcgtctaggggagatgcgcttcactctgggcaccttcctgcgcctg gcggccctgcgagtctaccagggcacgctggcctacctccctgcagaaagggtggtctcc caggtgcccgccccccctgccgtggagcgccaggatcagcagggtcccacggatgcccac cttgtacccctggaggagccggtgcccccgcactggactgtggtcccggagcaggacttc gtgctcgtgctggcgctgctgcactcccacctgggcagcgagatgtttgcggcccccatg ggccgatgtgcggccggcaccatgcatctcttctatgtgcgggcaggcgtgtctcgggcc atgctgctgcgcctcttcctggccatggagaaggggaggcacatggactatgactgtccc tacttggtgtacgtgcctgtggttgccttccgcctggagcccaaggacgggaagggtgtg tttgctgtggatggcgagttgatggtcagcgaggctgtgcagggccaggtgcacccagac tacgtctggatggtcagtggctgcatggagcccccacccagccagaagcctcagcaggga ccacctccaggcgagcccttatga

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