Ursus arctos (brown bear): 113247385 Help Entry 113247385         CDS       T05909                                  Symbol PRKCG Name (RefSeq) protein kinase C gamma type   KO K19663   classical protein kinase C gamma type [EC:2.7.11.13] Organism uah  Ursus arctos (brown bear) Pathway uah01521   EGFR tyrosine kinase inhibitor resistance uah04010   MAPK signaling pathway uah04012   ErbB signaling pathway uah04014   Ras signaling pathway uah04015   Rap1 signaling pathway uah04020   Calcium signaling pathway uah04066   HIF-1 signaling pathway uah04070   Phosphatidylinositol signaling system uah04071   Sphingolipid signaling pathway uah04082   Neuroactive ligand signaling uah04150   mTOR signaling pathway uah04270   Vascular smooth muscle contraction uah04310   Wnt signaling pathway uah04370   VEGF signaling pathway uah04510   Focal adhesion uah04540   Gap junction uah04613   Neutrophil extracellular trap formation uah04650   Natural killer cell mediated cytotoxicity uah04666   Fc gamma R-mediated phagocytosis uah04670   Leukocyte transendothelial migration uah04713   Circadian entrainment uah04720   Long-term potentiation uah04723   Retrograde endocannabinoid signaling uah04724   Glutamatergic synapse uah04725   Cholinergic synapse uah04726   Serotonergic synapse uah04727   GABAergic synapse uah04728   Dopaminergic synapse uah04730   Long-term depression uah04750   Inflammatory mediator regulation of TRP channels uah04911   Insulin secretion uah04916   Melanogenesis uah04918   Thyroid hormone synthesis uah04919   Thyroid hormone signaling pathway uah04921   Oxytocin signaling pathway uah04925   Aldosterone synthesis and secretion uah04928   Parathyroid hormone synthesis, secretion and action uah04929   GnRH secretion uah04935   Growth hormone synthesis, secretion and action uah04960   Aldosterone-regulated sodium reabsorption uah04961   Endocrine and other factor-regulated calcium reabsorption uah04970   Salivary secretion uah04971   Gastric acid secretion uah04972   Pancreatic secretion uah05017   Spinocerebellar ataxia uah05022   Pathways of neurodegeneration - multiple diseases uah05031   Amphetamine addiction uah05032   Morphine addiction uah05143   African trypanosomiasis uah05146   Amoebiasis uah05161   Hepatitis B uah05163   Human cytomegalovirus infection uah05170   Human immunodeficiency virus 1 infection uah05171   Coronavirus disease - COVID-19 uah05200   Pathways in cancer uah05205   Proteoglycans in cancer uah05206   MicroRNAs in cancer uah05207   Chemical carcinogenesis - receptor activation uah05214   Glioma uah05223   Non-small cell lung cancer uah05225   Hepatocellular carcinoma uah05231   Choline metabolism in cancer uah05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:uah00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     113247385 (PRKCG)    04012 ErbB signaling pathway     113247385 (PRKCG)    04014 Ras signaling pathway     113247385 (PRKCG)    04015 Rap1 signaling pathway     113247385 (PRKCG)    04310 Wnt signaling pathway     113247385 (PRKCG)    04370 VEGF signaling pathway     113247385 (PRKCG)    04066 HIF-1 signaling pathway     113247385 (PRKCG)    04020 Calcium signaling pathway     113247385 (PRKCG)    04070 Phosphatidylinositol signaling system     113247385 (PRKCG)    04071 Sphingolipid signaling pathway     113247385 (PRKCG)    04150 mTOR signaling pathway     113247385 (PRKCG)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     113247385 (PRKCG)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     113247385 (PRKCG)    04540 Gap junction     113247385 (PRKCG)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     113247385 (PRKCG)    04650 Natural killer cell mediated cytotoxicity     113247385 (PRKCG)    04666 Fc gamma R-mediated phagocytosis     113247385 (PRKCG)    04670 Leukocyte transendothelial migration     113247385 (PRKCG)   09152 Endocrine system    04911 Insulin secretion     113247385 (PRKCG)    04929 GnRH secretion     113247385 (PRKCG)    04921 Oxytocin signaling pathway     113247385 (PRKCG)    04935 Growth hormone synthesis, secretion and action     113247385 (PRKCG)    04918 Thyroid hormone synthesis     113247385 (PRKCG)    04919 Thyroid hormone signaling pathway     113247385 (PRKCG)    04928 Parathyroid hormone synthesis, secretion and action     113247385 (PRKCG)    04916 Melanogenesis     113247385 (PRKCG)    04925 Aldosterone synthesis and secretion     113247385 (PRKCG)   09153 Circulatory system    04270 Vascular smooth muscle contraction     113247385 (PRKCG)   09154 Digestive system    04970 Salivary secretion     113247385 (PRKCG)    04971 Gastric acid secretion     113247385 (PRKCG)    04972 Pancreatic secretion     113247385 (PRKCG)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     113247385 (PRKCG)    04961 Endocrine and other factor-regulated calcium reabsorption     113247385 (PRKCG)   09156 Nervous system    04724 Glutamatergic synapse     113247385 (PRKCG)    04727 GABAergic synapse     113247385 (PRKCG)    04725 Cholinergic synapse     113247385 (PRKCG)    04728 Dopaminergic synapse     113247385 (PRKCG)    04726 Serotonergic synapse     113247385 (PRKCG)    04720 Long-term potentiation     113247385 (PRKCG)    04730 Long-term depression     113247385 (PRKCG)    04723 Retrograde endocannabinoid signaling     113247385 (PRKCG)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     113247385 (PRKCG)   09159 Environmental adaptation    04713 Circadian entrainment     113247385 (PRKCG)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     113247385 (PRKCG)    05206 MicroRNAs in cancer     113247385 (PRKCG)    05205 Proteoglycans in cancer     113247385 (PRKCG)    05207 Chemical carcinogenesis - receptor activation     113247385 (PRKCG)    05231 Choline metabolism in cancer     113247385 (PRKCG)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     113247385 (PRKCG)    05214 Glioma     113247385 (PRKCG)    05223 Non-small cell lung cancer     113247385 (PRKCG)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     113247385 (PRKCG)    05161 Hepatitis B     113247385 (PRKCG)    05171 Coronavirus disease - COVID-19     113247385 (PRKCG)    05163 Human cytomegalovirus infection     113247385 (PRKCG)   09174 Infectious disease: parasitic    05146 Amoebiasis     113247385 (PRKCG)    05143 African trypanosomiasis     113247385 (PRKCG)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     113247385 (PRKCG)    05022 Pathways of neurodegeneration - multiple diseases     113247385 (PRKCG)   09165 Substance dependence    05031 Amphetamine addiction     113247385 (PRKCG)    05032 Morphine addiction     113247385 (PRKCG)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     113247385 (PRKCG)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     113247385 (PRKCG)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:uah01001]     113247385 (PRKCG) Enzymes [BR:uah01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      113247385 (PRKCG) Protein kinases [BR:uah01001]  Serine/threonine kinases: AGC group   PKC family [OT]    113247385 (PRKCG) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C ABC1 Kinase-like Motif Other DBs NCBI-GeneID:  113247385 NCBI-ProteinID:  XP_026344199 LinkDB All DBs Position Unknown AA seq 697 aa AA seqDB search MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHVTVGEA RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDSKRCFFGTSPGRLHISDFSFLMVLGKG SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD LKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPAKRLGS GPDGEPAIRAHGFFRWMDWERLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL VLASIDQADFQGFTYVNPDFVHPDARSPISPPPVPVM NT seq 2094 nt NT seq  +upstreamnt  +downstreamnt atggcaggcctgggccccggcggaggcgattcagaggggggaccccggcccctgttttgc agaaagggggctctgaggcagaaggtggtccacgaagtcaagagccacaagttcaccgcc cgcttcttcaagcagccaaccttctgcagccactgcaccgacttcatctggggaattgga aaacagggcctgcaatgtcaagtctgcagctttgtggttcatcgacgatgccacgaattt gtgaccttcgagtgtccaggcgctgggaagggcccccagacggatgacccccggaacaag cacaagttccgtctgcacagctacagcagccccaccttttgcgaccactgcggctccctc ctctacgggctggtgcaccagggcatgaaatgctcctgctgcgagatgaacgtgcaccga cgctgtgtgcgcagcgtgccctctctgtgcggggtggaccacaccgagcgccgtgggcgc ctgcagctggaaatccgggcaccgacggcagatgagatacacgtcacagttggcgaggcc cgtaacctcatcccgatggatcccaatggtctgtctgatccctatgtgaagctgaagctc atcccagaccctcggaacttgacgaaacagaagacccgaacagtgaaagccacactaaac cctgtgtggaacgagacctttgtgttcaacctgaagccgggggacgtggagcgccggctc agcgtggaggtgtgggactgggaccggacttcccgcaatgatttcatgggtgccatgtcc ttcggtgtctcggagctgctcaaggcgccagtggacggctggtacaagttactgaaccag gaggagggcgagtattacaatgtgccggtggctgacgctgacaactgcagcctcctccag aagtttgaggcctgtaactaccccctggaactgtatgagcgggtgcggatgggtccctct tcctctcccatcccttccccatctcccagtcccaccgactccaagcgctgtttctttggg acgagccctggacgtctgcacatctctgacttcagcttcctcatggttctaggaaaaggc agttttgggaaggtgatgctggctgagcgcaggggctccgatgagctctacgccatcaag atcctgaagaaagacgtgattgttcaggatgacgacgtggactgcaccctggtggagaag cgagtgctggccctggggggccgaggcccgggcggccggccccactttctcacccagctg cattcgaccttccagaccccggatcgcctgtattttgtgatggagtatgtcacggggggc gacctgatgtaccacatccagcagctgggcaagtttaaggagccccatgcagcgttctac gcagcggaaatcgccatcggcctcttcttccttcacaatcagggcatcatatatcgggac ctgaaactagacaacgtgatgctggacgccgaaggacacatcaaaatcacggacttcggc atgtgtaaggagaacgtcttccccgggaccacgacccgcactttctgcgggaccccagac tacatagcccctgagatcattgcctaccagccctatgggaagtctgtggattggtggtcc tttggggttctgctgtatgagatgctggcaggacagcccccttttgacggggaggatgag gaagagctctttcaggccatcatggaacaaactgtcacttaccccaagtcactttcccgg gaagccgtggcgatctgcaaggggttcctaactaagcacccagcgaagcgcctgggctca gggccagacggggagcccgccatccgtgctcatggctttttccgctggatggactgggag cgcctggaacgactggagatcgcgcctccgttcagaccccgtccgtgtggacgcagcggt gagaacttcgacaaattcttcacgcgggcggcgccagcgctgaccccgccagaccgccta gtgttggccagcatcgaccaggccgatttccaaggcttcacctacgtgaacccggatttc gtgcacccggacgcccgcagccccatcagcccaccgcctgtgccagtcatgtaa

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