Ursus arctos (brown bear): 113248466
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Entry
113248466 CDS
T05909
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah01522
Endocrine resistance
uah04012
ErbB signaling pathway
uah04062
Chemokine signaling pathway
uah04148
Efferocytosis
uah04151
PI3K-Akt signaling pathway
uah04360
Axon guidance
uah04370
VEGF signaling pathway
uah04510
Focal adhesion
uah04517
IgSF CAM signaling
uah04518
Integrin signaling
uah04670
Leukocyte transendothelial migration
uah04810
Regulation of actin cytoskeleton
uah04935
Growth hormone synthesis, secretion and action
uah05100
Bacterial invasion of epithelial cells
uah05135
Yersinia infection
uah05146
Amoebiasis
uah05163
Human cytomegalovirus infection
uah05165
Human papillomavirus infection
uah05170
Human immunodeficiency virus 1 infection
uah05200
Pathways in cancer
uah05202
Transcriptional misregulation in cancer
uah05205
Proteoglycans in cancer
uah05208
Chemical carcinogenesis - reactive oxygen species
uah05222
Small cell lung cancer
uah05417
Lipid and atherosclerosis
uah05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
113248466 (PTK2)
04370 VEGF signaling pathway
113248466 (PTK2)
04151 PI3K-Akt signaling pathway
113248466 (PTK2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
113248466 (PTK2)
04518 Integrin signaling
113248466 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
113248466 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
113248466 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
113248466 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
113248466 (PTK2)
04062 Chemokine signaling pathway
113248466 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
113248466 (PTK2)
09158 Development and regeneration
04360 Axon guidance
113248466 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113248466 (PTK2)
05202 Transcriptional misregulation in cancer
113248466 (PTK2)
05205 Proteoglycans in cancer
113248466 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
113248466 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
113248466 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
113248466 (PTK2)
05163 Human cytomegalovirus infection
113248466 (PTK2)
05165 Human papillomavirus infection
113248466 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
113248466 (PTK2)
05100 Bacterial invasion of epithelial cells
113248466 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
113248466 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113248466 (PTK2)
05418 Fluid shear stress and atherosclerosis
113248466 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
113248466 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113248466 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
uah01009
]
113248466 (PTK2)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
113248466 (PTK2)
Protein kinases [BR:
uah01001
]
Non-receptor tyrosine kinases
FAK family
113248466 (PTK2)
Protein phosphatases and associated proteins [BR:
uah01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
113248466 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
113248466
NCBI-ProteinID:
XP_048068371
LinkDB
All DBs
Position
Unknown
AA seq
1103 aa
AA seq
DB search
MLLELAGREALRPAGAVCMEKSGCSPFPMCWAKEYDRYIASSKIMAAAYLDPNLNHTPNS
STKTHLGTGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGVRTHAVSVSETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIG
EGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGV
ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAA
RNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFG
VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF
TELKAQLSTILEEEKVQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGF
YPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRQQEISMWQPNME
DSAALDLRGIGQGLPAHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDV
GLQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKLQPQEI
SPPPTANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVD
ETLPVLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAV
DAKNLLDVIDQARLRMLGTTRPH
NT seq
3312 nt
NT seq
+upstream
nt +downstream
nt
atgttgctggaactggcgggccgagaggccctgagaccagcaggtgccgtctgtatggag
aagagcggctgtagtccatttccaatgtgttgggctaaagagtatgacagatacatagca
tctagcaaaataatggcagctgcttaccttgacccaaacttgaatcacacaccgaattcg
agtaccaaaactcacctgggtactggagtggaacgttcccctggggcaatggagcgagtg
ttgaaggtctttcattattttgaaaacagcagtgagccagctacctgggccagtattatc
aggcatggagatgctaccgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgcctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccaactctgaatttcttctatcaacaggtgaagagcgactacatg
tcagagatagctgaccgcgtggaccaggacattgctttgaagttgggctgtctagaaata
cggcgctcgtactgggagatgcgaggcaacgcgctagagaagaagtccaactatgaagtg
ttagaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacactaagaaagctgatccaacagacatttagacagtttgccaaccttaataga
gaagaaagtattttgaagttctttgagatcctctccccggtgtacagatttgataaagaa
tgcttcaagtgtgctctgggttcaagctggattatttcggtggaactggcaattggccca
gaagaaggaatcagttacctcacggacaagggctgcaaccccacacatctggccgacttc
aatcaagtgcagaccattcagtattcgaacagcgaagacaaggacaggaaggggatgctg
cagctgaaaatcgccggcgcccccgagcctctgacagtgacagcgccgtccctaaccatc
gccgagaatatggctgacttgatagatgggtactgccggctggtgaacggggccacacag
tcttttatcatcagaccccagaaagaaggtgaacgggctttgccatcaataccaaagctg
gccaacagcgagaagcaaggcgtgcggacacacgcggtctccgtatcagaaacagatgat
tatgctgagattatagacgaagaagatacctacaccatgccctcaaaaagctatggaata
gatgaagccagggattatgagattcagagagaaaggatcgagcttggacggtgcatcggg
gaaggccagtttggagacgtccatcaaggcgtctatatgagcccggagaatccagctttg
gcggttgcaattaaaacatgtaaaaactgtacttcggacagcgtgagagagaaattcctt
caagaagccttaacaatgcgtcagtttgaccaccctcacattgtgaagctgattggcgtc
atcacggagaaccctgtctggataatcatggagctgtgcacgcttggagagctgaggtca
tttctgcaagtaaggaagtacagtttggatctagcgtctttgatcctatatgcctatcaa
cttagtacagcccttgcgtatctggagagcaaaagatttgtgcacagggacattgctgct
cggaatgttctggtgtcctcaaatgattgcgtaaaactgggagactttggattatcccga
tacatggaagacagtacttactacaaagcttccaaaggaaaattgccaattaagtggatg
gctccagagtccatcaattttcgacgttttacctcagctagtgatgtgtggatgtttggt
gtatgtatgtgggagatcctgatgcatggtgtgaagccttttcaaggagtgaagaacaat
gatgtgattggtcgaattgagaatggggagagattaccaatgcctccaaattgccctcct
accctctacagccttatgacgaaatgctgggcctatgaccccagcaggcggccccggttc
actgagctcaaagctcagctcagcacaatcctggaggaggagaaggttcagcaagaagaa
cggatgaggatggagtccagaagacaggtcacagtgtcctgggactccggagggtccgac
gaagcgccacccaagcccagcagacccggttaccctagtccaaggtccagcgaaggattt
tatcctagtccacagcacatggtacagaccaatcattaccaggtctctggctatcctggt
tcacatgggatcacagccatggctggcagcatctacccggggcaggcatctcttttggac
cagacggattcctggaatcatagacagcaggagatatcaatgtggcagcccaacatggag
gactctgctgcgctggacctgcgagggatcggacaggggctgccggcccacctgatggaa
gagcggctgatccggcagcagcaggagatggaggaagatcagcgctggctagaaaaagag
gagagatttctgaaacctgacgtgcggctctctcgaggcagtatcgacagggaggacgtt
ggtctccagggcccgactggaaaccaacacatatatcagcctgtggggaaaccagatccc
gcagctccgccaaagaaaccgccccggcctggggcccccggtcacctgggcagcctcgcc
agcctcagcagccccggggacagttacaacgagggcgtcaagcttcagccccaggaaatc
agccccccgcccactgccaacctggaccggtccaatgacagagtgtacgagaacgtgacg
ggcctggtaaaggctgtcatcgagatgtccagcaagatccagccagccccaccagaggag
tacgtccccatggtgaaggaagtcggcctggccctgcggacgttactggccactgtggac
gagacccttccggtcctgccagccagcactcaccgagagattgaaatggcccagaagctg
ttgaactccgacctgggtgagctcatcaacaagatgaaactggcccagcagtacgtcatg
accagtctccagcaggagtacaagaagcaaatgctgaccgctgctcacgccctggccgtg
gacgccaagaacttactcgacgtcattgaccaagcgagactgcggatgcttggaacgacg
aggccgcactga
DBGET
integrated database retrieval system
