Ursus arctos horribilis (North American brown bear): 113252326
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Entry
113252326 CDS
T05909
Symbol
ADCY5
Name
(RefSeq) adenylate cyclase type 5
KO
K08045
adenylate cyclase 5 [EC:
4.6.1.1
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah00230
Purine metabolism
uah01100
Metabolic pathways
uah01522
Endocrine resistance
uah04015
Rap1 signaling pathway
uah04022
cGMP-PKG signaling pathway
uah04024
cAMP signaling pathway
uah04062
Chemokine signaling pathway
uah04072
Phospholipase D signaling pathway
uah04114
Oocyte meiosis
uah04211
Longevity regulating pathway
uah04213
Longevity regulating pathway - multiple species
uah04261
Adrenergic signaling in cardiomyocytes
uah04270
Vascular smooth muscle contraction
uah04371
Apelin signaling pathway
uah04540
Gap junction
uah04611
Platelet activation
uah04713
Circadian entrainment
uah04714
Thermogenesis
uah04723
Retrograde endocannabinoid signaling
uah04724
Glutamatergic synapse
uah04725
Cholinergic synapse
uah04726
Serotonergic synapse
uah04727
GABAergic synapse
uah04728
Dopaminergic synapse
uah04750
Inflammatory mediator regulation of TRP channels
uah04911
Insulin secretion
uah04912
GnRH signaling pathway
uah04913
Ovarian steroidogenesis
uah04914
Progesterone-mediated oocyte maturation
uah04915
Estrogen signaling pathway
uah04916
Melanogenesis
uah04918
Thyroid hormone synthesis
uah04921
Oxytocin signaling pathway
uah04923
Regulation of lipolysis in adipocytes
uah04924
Renin secretion
uah04925
Aldosterone synthesis and secretion
uah04926
Relaxin signaling pathway
uah04927
Cortisol synthesis and secretion
uah04928
Parathyroid hormone synthesis, secretion and action
uah04934
Cushing syndrome
uah04935
Growth hormone synthesis, secretion and action
uah04970
Salivary secretion
uah04971
Gastric acid secretion
uah04972
Pancreatic secretion
uah04976
Bile secretion
uah05012
Parkinson disease
uah05030
Cocaine addiction
uah05031
Amphetamine addiction
uah05032
Morphine addiction
uah05034
Alcoholism
uah05163
Human cytomegalovirus infection
uah05166
Human T-cell leukemia virus 1 infection
uah05200
Pathways in cancer
uah05207
Chemical carcinogenesis - receptor activation
uah05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
113252326 (ADCY5)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
113252326 (ADCY5)
04371 Apelin signaling pathway
113252326 (ADCY5)
04072 Phospholipase D signaling pathway
113252326 (ADCY5)
04024 cAMP signaling pathway
113252326 (ADCY5)
04022 cGMP-PKG signaling pathway
113252326 (ADCY5)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
113252326 (ADCY5)
09144 Cellular community - eukaryotes
04540 Gap junction
113252326 (ADCY5)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113252326 (ADCY5)
04062 Chemokine signaling pathway
113252326 (ADCY5)
09152 Endocrine system
04911 Insulin secretion
113252326 (ADCY5)
04923 Regulation of lipolysis in adipocytes
113252326 (ADCY5)
04912 GnRH signaling pathway
113252326 (ADCY5)
04913 Ovarian steroidogenesis
113252326 (ADCY5)
04915 Estrogen signaling pathway
113252326 (ADCY5)
04914 Progesterone-mediated oocyte maturation
113252326 (ADCY5)
04921 Oxytocin signaling pathway
113252326 (ADCY5)
04926 Relaxin signaling pathway
113252326 (ADCY5)
04935 Growth hormone synthesis, secretion and action
113252326 (ADCY5)
04918 Thyroid hormone synthesis
113252326 (ADCY5)
04928 Parathyroid hormone synthesis, secretion and action
113252326 (ADCY5)
04916 Melanogenesis
113252326 (ADCY5)
04924 Renin secretion
113252326 (ADCY5)
04925 Aldosterone synthesis and secretion
113252326 (ADCY5)
04927 Cortisol synthesis and secretion
113252326 (ADCY5)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
113252326 (ADCY5)
04270 Vascular smooth muscle contraction
113252326 (ADCY5)
09154 Digestive system
04970 Salivary secretion
113252326 (ADCY5)
04971 Gastric acid secretion
113252326 (ADCY5)
04972 Pancreatic secretion
113252326 (ADCY5)
04976 Bile secretion
113252326 (ADCY5)
09156 Nervous system
04724 Glutamatergic synapse
113252326 (ADCY5)
04727 GABAergic synapse
113252326 (ADCY5)
04725 Cholinergic synapse
113252326 (ADCY5)
04728 Dopaminergic synapse
113252326 (ADCY5)
04726 Serotonergic synapse
113252326 (ADCY5)
04723 Retrograde endocannabinoid signaling
113252326 (ADCY5)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
113252326 (ADCY5)
09149 Aging
04211 Longevity regulating pathway
113252326 (ADCY5)
04213 Longevity regulating pathway - multiple species
113252326 (ADCY5)
09159 Environmental adaptation
04713 Circadian entrainment
113252326 (ADCY5)
04714 Thermogenesis
113252326 (ADCY5)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113252326 (ADCY5)
05207 Chemical carcinogenesis - receptor activation
113252326 (ADCY5)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113252326 (ADCY5)
05163 Human cytomegalovirus infection
113252326 (ADCY5)
09164 Neurodegenerative disease
05012 Parkinson disease
113252326 (ADCY5)
09165 Substance dependence
05030 Cocaine addiction
113252326 (ADCY5)
05031 Amphetamine addiction
113252326 (ADCY5)
05032 Morphine addiction
113252326 (ADCY5)
05034 Alcoholism
113252326 (ADCY5)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
113252326 (ADCY5)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
113252326 (ADCY5)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
113252326 (ADCY5)
Enzymes [BR:
uah01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
113252326 (ADCY5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AC_N
Guanylate_cyc
Adcy_cons_dom
TBK1_ULD
GBR2_CC
PEN-2
Motif
Other DBs
NCBI-GeneID:
113252326
NCBI-ProteinID:
XP_026350697
LinkDB
All DBs
Position
Unknown
AA seq
1264 aa
AA seq
DB search
MSGSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPHAPGGSTRGCTKKPGGA
VTPQQRQQQQQQRLANRWRGDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGS
RRQRRGAAGGGSTRAPPAGGGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRAVDELEA
GAVDGDEGSGDGGSSAESGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRL
NQSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDH
MGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLL
SALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQA
RLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEG
FTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCC
VEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEA
GGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIA
KMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVD
EFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICF
VQITIVPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPTPLQTLSRKIVRSKMNSTLV
GVFTITLVFLSAFVNMFTCNSNDLFGCLADEHNISTSQVNACHVVESAANYSLGDERGFC
SSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELTYVLIVEVPRVTLFDN
ADLLVTANAIDFNNNGTSQCPEHATKVALKVMTPIVISVFVLALYLHAQQVESTARLDFL
WKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASI
ANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFKQLEKIKTIGSTYMAASGLND
STYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYD
IWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGG
PPLS
NT seq
3795 nt
NT seq
+upstream
nt +downstream
nt
atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagacagcagcggcgccg
gcgtcccggggaggcccggaacaccgctcggcgtggggggaggcagattcccgcgccaat
ggctacccccacgcccctgggggttcgacccgtggctgcaccaagaaacccgggggggcg
gtgaccccgcagcagcggcagcagcagcagcagcagcgcctggccaaccgctggcgcggc
gacgacgacgacgatcctccgctgagtggcgacgaccccctggccgggggcttcggcttc
agcttccgctccaagtcggcttggcaggagcgcggcggcgacgactgcggtcgcggcagc
cgccggcagcggcggggcgcggccggcgggggtagcacccgggcgccccctgcgggcggc
ggtggcggctcggcggcggcggcggccgcggccggcgggacggaggtgcgccctcggtcg
gtggagctgggcctggaggagcggcggggcaagggccgcgcggtggacgagctggaggcc
ggcgccgtcgacggcgacgaagggtccggggatggcggcagctcggcagaatcaggcgcg
gggcccggcgcagtgctgtcgctgggtgcctgctgcctggcgctgctgcagatattccgt
tccaagaagttcccgtcggacaagctggagcggctgtaccagcgctacttcttccgtctg
aaccagagcagcctcactatgctcatggccgtgctggtgctcgtgtgcctcgtcatgttg
gccttccacgcggcgcggcccccgctccagctgccctacctggcagtgctggcggctgcg
gtaggtgtcatcctcgtcatggctgtgctctgcaaccgcgccgccttccaccaggaccac
atgggcctggcctgctacgcgctcatcgccgtggtgctggccgtccaggtggtgggcctg
ctgctgccccagccgcgcagcgcctccgagggcatctggtggaccgtgttcttcatctac
accatctacacgttgctgcctgtgcgcatgcgggccgcggtactcagtggagtgctcctt
tctgcactccacctggccatcgccctgcgcaccaacgcccaggaccagttcctgctcaag
cagcttgtctccaatgtcctcattttctcctgcaccaacattgtgggtgtttgcacccac
tacccggctgaagtctcccagagacaggccttccaggagacccgggagtgcatccaggca
cggctccactcacaacgggagaaccaacaacaggagcggctcctgctgtctgtcctgccc
cgtcatgttgccatggagatgaaagcagacatcaatgccaagcaggaggatatgatgttc
cataagatttacatccagaaacacgacaacgtgagcatcctgtttgctgacatcgagggc
ttcaccagcctggcatcccagtgcactgcccaggagctggtcatgaccctcaacgagctc
ttcgcccgcttcgacaagctggctgcggagaatcactgtttacgtattaagatcctgggg
gattgttattactgtgtctctgggctgcctgaagcgagggctgaccacgcccactgctgc
gtggagatgggcatggacatgattgaggccatctcgttggtccgggaggtgacaggggtg
aacgtgaacatgcgcgtgggaattcacagcgggcgagtacactgcggtgtccttggtctc
aggaagtggcaattcgacgtctggtctaatgacgtcacgctggccaaccacatggaagct
ggaggcaaggcagggcgcatccacatcaccaaggccacactcaactacctgaacggggac
tacgaggtggagccgggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatc
gagaccttcctcatcctgcgctgcacccagaagcggaaagaagaaaaggccatgatcgcc
aagatgaatcgccagagaaccaactccattgggcacaacccgccccactggggggccgag
cgtcccttctacaaccacctggggggcaaccaggtgtccaaggagatgaagcggatgggc
ttcgaagaccccaaggacaagaacgcccaagaaagcgcaaaccctgaggacgaagtggac
gaatttctgggccgtgccattgacgccaggagcatcgacaggctgcggtctgagcatgtc
cgcaagttcctcttgaccttcagggagcctgacttagagaagaagtactccaagcaggtg
gatgaccgattcggtgcctacgtggcatgtgcctcgcttgtcttcctcttcatctgcttt
gtccagatcaccatcgtgccccactccgtgttcatgttgagtttctacctaacctgtttc
ctgctgctgacgttagtggtatttgtgtccgtgatctattcctgcgtgaagctgttcccc
accccactgcagaccctctccaggaagattgtgcggtccaagatgaacagcactctggtt
ggcgtgttcaccatcaccctcgtgttcctctcggcttttgtcaacatgttcacgtgtaac
tccaacgacctgttcggctgcctggcggatgagcacaacatcagcaccagccaggtcaac
gcgtgccacgtggtggagtcggccgccaactacagcctgggggacgagcggggcttctgc
agcagcccgtggcccaactgcaacttccctgagtacttcacctacagcgtgctgctcagc
ctgctggcctgctccgtgttcctgcagatcagctgcattgggaagctggtgctcatgctg
gccattgagctcacatacgtgctcatcgtcgaggtgccccgagtcacgctctttgacaat
gccgacctgctggtcaccgccaatgccatagacttcaacaacaacgggacctcccagtgc
cctgagcatgcgaccaaggtggcgctgaaggtgatgacgcccatcgtcatctccgtcttt
gtgctggccctgtacctgcacgcccagcaagtggagtccaccgcccgcctggacttcctc
tggaaactgcaggccacggaggagaaggaggagatggaggagctgcaggcctacaaccgg
cggctgctgcacaacatcctgcccaaggacgtggctgcccacttcctggcccgcgagcgg
cgcaacgacgagctctactaccagtcgtgcgagtgcgtggccgtcatgtttgcctccatc
gccaacttctccgagttctatgtggagctggaggccaacaatgagggcgtcgagtgcctg
cggctgctcaatgagatcatcgccgactttgacgagatcatcagtgaggatcggttcaag
cagctggagaagatcaagaccattggcagcacctacatggccgcctcaggcctcaacgac
tctacgtatgacaaggtgggcaagacccacatcaaagccctggccgacttcgccatgaag
ctcatggaccaaatgaagtacatcaatgaacactccttcaacaacttccagatgaagatc
gggctcaacatcggccctgtggtggccggggtgatcggggctcgcaagccgcagtacgac
atctggggcaatacggtgaacgtggccagccgcatggacagcaccggtgtgcccgaccgc
atccaggtcaccacggacatgtaccaggtgctggctgccaacacataccagctggagtgc
aggggtgtggtcaaggtcaagggcaaaggcgagatgatgacctacttcctcaacgggggc
cccccgctcagttag
DBGET
integrated database retrieval system
