Ursus arctos horribilis (North American brown bear): 113258514
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Entry
113258514 CDS
T05909
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah04120
Ubiquitin mediated proteolysis
uah04144
Endocytosis
uah04330
Notch signaling pathway
uah04668
TNF signaling pathway
uah04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
113258514 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
113258514 (ITCH)
04668 TNF signaling pathway
113258514 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
113258514 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
113258514 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
uah04131
]
113258514 (ITCH)
04121 Ubiquitin system [BR:
uah04121
]
113258514 (ITCH)
Enzymes [BR:
uah01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
113258514 (ITCH)
Membrane trafficking [BR:
uah04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
113258514 (ITCH)
Ubiquitin system [BR:
uah04121
]
Ubiquitin ligases (E3)
HECT type E3
113258514 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
113258514
NCBI-ProteinID:
XP_026359109
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGETTCSESASQNDDGSRPKDETRTNTNGS
DEPEDAGAGENRKVNGDNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNPIPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccgagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaagtgcaacaataca
aacagtcccaaatggaagcagccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccaacagagacaataggagacttgtcagtttgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagaacaaacacaaatggatca
gatgagcctgaagatgcaggagctggtgaaaataggaaggtcaatggggataattctcca
tcactctcaaatggtggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatccagtacgggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctctgactatatctggaggctcaggccctaggccattaaat
cctatacctcaggctcccctaccacctggttgggagcagagagtggaccagcatggacga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggttgggaacggcgggttgacaacatgggacgtatttactatgttgaccatttcaca
agaacaacaacatggcagaggccaacattggaatccgtccggaactatgaacagtggcag
ctacaacgtagtcagctgcaaggagcaatgcagcagtttaaccagagatttatttatggg
aatcaagatttatttactacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacgcaatgggaagaccccagaagtcaaggtcagttaaatgaaaaacctttacct
gaaggctgggaaatgagattcacagtcgatggaattccatattttgtggaccacaataga
agaacaactacctatattgatccccgcactggaaaatctgccctagacaatggaccacag
atagcctacgtacgggacttcaaggcaaaagttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacggtgacaagaaagacattgtttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagattaatcctgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctctgttccatgggaaattcatagacacgggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtctg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggcaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggagttagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctgcagtttgttactggaacctgcagattgccagttggagga
tttgctgacctcatggggagcaatggaccacaaaaattctgcattgaaaaagttgggaaa
gaaaactggttacccagaagtcatacgtgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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