Ursus arctos (brown bear): 113259127 Help Entry 113259127         CDS       T05909                                  Symbol HKDC1 Name (RefSeq) hexokinase HKDC1   KO K00844   hexokinase [EC:2.7.1.1] Organism uah  Ursus arctos (brown bear) Pathway uah00010   Glycolysis / Gluconeogenesis uah00051   Fructose and mannose metabolism uah00052   Galactose metabolism uah00500   Starch and sucrose metabolism uah00520   Amino sugar and nucleotide sugar metabolism uah00524   Neomycin, kanamycin and gentamicin biosynthesis uah01100   Metabolic pathways uah01200   Carbon metabolism uah01250   Biosynthesis of nucleotide sugars uah04066   HIF-1 signaling pathway uah04910   Insulin signaling pathway uah04930   Type II diabetes mellitus uah04973   Carbohydrate digestion and absorption uah05230   Central carbon metabolism in cancer Module uah_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate uah_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc uah_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:uah00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     113259127 (HKDC1)    00051 Fructose and mannose metabolism     113259127 (HKDC1)    00052 Galactose metabolism     113259127 (HKDC1)    00500 Starch and sucrose metabolism     113259127 (HKDC1)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     113259127 (HKDC1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     113259127 (HKDC1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     113259127 (HKDC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     113259127 (HKDC1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     113259127 (HKDC1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     113259127 (HKDC1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     113259127 (HKDC1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uah04131]     113259127 (HKDC1) Enzymes [BR:uah01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      113259127 (HKDC1) Membrane trafficking [BR:uah04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     113259127 (HKDC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  113259127 NCBI-ProteinID:  XP_026360145 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MFAVHLMAFYFSKLKEDQIKKVDRFLYDMRLSDETLLDIMTRFQAEMQKGLGKDTNPTAA VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSQEGKRNVQMESQFYPTPNEIIR GNGSELFDYVADCLADFMKTKGLKHKKLPLGLTFSFPCRQTKLEEGILLSWTKKFKARGV QDTDVVSCLTKAMRKHKDIDVDILALVNDTVGTLMTCAYDDPYCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCVNTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL YLGELVRIILLKMAKAGLLFGGKKSSALHTKGKIETRHVAAMEKYKEGLANTREILTDLG LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRVNKKLARLRTTVGMDGTVYKIH PQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLT REQLEDVRGKMRAEFEYGLKKDTHLTATVKMLPTYVCGMPDGTEKGKFLALDLGGTNFRV LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFT FSFPCRQTSIDKGTLIEWTKGFKATDCEGEDMVDMLREAIKRRNEFDLDIVAVVNDTVGT MMTCGHEDPNCEIGLIAGTGSNMCYMEEMRNIELVEGDEGKMCINTEWGGFGDNGCIDDI RTQYDKKVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAV VEKRREDQGLEYLKITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTLMLSEDGSGKGA ALITAVAKRLQQAQKEN NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgtttgcggtacacttgatggcattttacttcagcaagctgaaggaagatcagatcaag aaggtggacaggttcctgtatgacatgcggctctccgatgagacccttttggacatcatg actcgcttccaggctgaaatgcagaagggcctggggaaggacaccaaccccacagccgcc gtgaagatgctgcccacctttgtcagggccattccagatggctcagaaaatggggagttt ctttctctggatcttggagggtccaaatttcgtgtcttgaaggtacaagtctctcaagag gggaaaagaaacgtccagatggagagtcagttctacccaacacccaatgaaattatccga ggcaatggctccgagctgtttgactacgtagctgactgtctggcagatttcatgaagacg aaagggttgaagcataagaaattgccccttggcctaaccttctcttttccatgcagacag actaagttggaagaggggatcctgctttcatggaccaagaagtttaaggcacggggagtt caagacacagatgtcgtgagttgtctgaccaaagccatgagaaaacacaaggacatagac gtggacatcctggccttggtcaatgacaccgtggggaccctgatgacatgcgcctatgat gatccctactgtgaagttggtgtcatcattggcaccggcaccaacgcgtgttacatggag gacatgagcaacattgacctggtggagggcgatgaggggaggatgtgcgtcaacacggag tggggggccttcggcgacgacggggctctggaagacatccgcaccgagttcgaccgggag ctggacctcggctctctcaaccccgggaagcaactgtttgagaagatgatcagtggcctg tacctgggtgaacttgtcaggatcatcttgctgaagatggccaaggcaggtctcctgttt ggcggcaagaagtcctctgctctccacacaaagggcaagattgaaacacggcacgtggct gccatggagaagtataaggaaggccttgccaatacaagagagatcctgacagatctgggc ctggagccttcggaggccgactgcatcgcggtccagcacgtctgcaccatcgtctccttc cgttcagccaacctgtgtgcagcggccctggcagccatcctgacgcgcctgcgggtgaac aagaagctggcacggctccgcaccacggtgggcatggacggcacggtctacaagatacac cctcaataccccaaacgcctgcacaaagtggtgaggagactggtcccgaactgtgacgtc cgcttcctcttgtcggagagtggcagcaccaagggggctgccatggtgacagcggtggcc tcccgagtgcaggcccagcggaagcagatcgacaaggtgctggctctgttccagctgact cgagagcagcttgaggacgtgcggggcaagatgcgggctgagttcgagtacgggctgaaa aaggacacccacctgacagccacagtcaagatgctgcccacctacgtctgcgggatgccg gatggcacagagaaaggaaagttccttgccctggatctggggggaaccaacttccgggtc ctcctggtaaagatcagaagcggacggaggtcggtgcgaatgtacaacaagatctttgcc atccccttggagatcatgcagggcaccggcgaggagctgttcgatcacatcgtgcagtgc attgctgacttcctggactacatgggcctcaagggagcccagctgcctttgggcttcacg ttctcatttccctgcaggcagacgagcatcgacaagggaacgctcattgagtggaccaaa ggcttcaaggccacggattgtgaaggggaagacatggtggacatgctcagggaagccatc aagaggagaaatgagttcgacctggacatagttgcagttgtgaatgacacagtggggacc atgatgacctgcggccatgaagatcctaattgtgagattggcctgattgcaggaacaggc agcaacatgtgctacatggaggagatgaggaacattgagctggtggaaggggacgaaggg aagatgtgcattaacacagaatggggaggatttggagataatggctgcatagacgacatc cggacccaatatgacaagaaggtggatgaggggtccttgaaccctggcaaacagagatat gagaaaatgaccagtgggatgtacctgggggagattgtgcggcagatcctgattgacctg accaagcagggtctccttttccgtgggcagatttcagagcgtctccggaccaggggcatc tttgaaaccaagttcctgtcccagattgaaagtgatcggctggccctcctccaggtcagg aggatcctgcagcagctcggcctggacagcacatgtgaggacagcattgtggtgaaggag gtgtgcggagctgtgtcccggcgggcggcccagctctgcggcgctggcctggctgctgtc gtggagaagaggagggaagaccaggggctggagtacctgaagatcaccgtgggagtggat ggcacgctgtacaagctgcaccctcacttttctcggatattgcaggaaactgtgaaagag ctagctcctcgatgtgatgtgacgctcatgctgtctgaagatgggagtggaaagggagct gctctgatcactgctgtggccaagaggttacagcaggcccagaaggagaactag

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