Ursus arctos (brown bear): 113259128 Help Entry 113259128         CDS       T05909                                  Symbol HK1 Name (RefSeq) hexokinase-1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism uah  Ursus arctos (brown bear) Pathway uah00010   Glycolysis / Gluconeogenesis uah00051   Fructose and mannose metabolism uah00052   Galactose metabolism uah00500   Starch and sucrose metabolism uah00520   Amino sugar and nucleotide sugar metabolism uah00524   Neomycin, kanamycin and gentamicin biosynthesis uah01100   Metabolic pathways uah01200   Carbon metabolism uah01250   Biosynthesis of nucleotide sugars uah04066   HIF-1 signaling pathway uah04910   Insulin signaling pathway uah04930   Type II diabetes mellitus uah04973   Carbohydrate digestion and absorption uah05230   Central carbon metabolism in cancer Module uah_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate uah_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc uah_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:uah00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     113259128 (HK1)    00051 Fructose and mannose metabolism     113259128 (HK1)    00052 Galactose metabolism     113259128 (HK1)    00500 Starch and sucrose metabolism     113259128 (HK1)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     113259128 (HK1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     113259128 (HK1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     113259128 (HK1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     113259128 (HK1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     113259128 (HK1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     113259128 (HK1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     113259128 (HK1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uah04131]     113259128 (HK1) Enzymes [BR:uah01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      113259128 (HK1) Membrane trafficking [BR:uah04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     113259128 (HK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Sec23_helical UvrD-helicase Motif Other DBs NCBI-GeneID:  113259128 NCBI-ProteinID:  XP_026360146 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFKKEMKNGLSRDFNPTAT VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQNVHMESEIYDTPENIVH GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEGILITWTKKFKASGV EGMDVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME ELRHIDLVEGDEGRMCVNTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM YLGELVRLILVKMAKESLLFEGRITPELLTRGKFKTSDVSAIEKNKEGLHNAKEILTRLG VEPSDDDCISVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFRLT KDMLLEVKKRMRAEMDMGLRKQTHEKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPKMPLGF TFSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLREAIKRREEFDLDVVAVVNDTVG TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVETLEGNDGRMCINMEWGAFGDNGCLDD IRTLYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG IFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA VVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMYQTVKELSPKCNVSFLLSEDGSGKG AALITAVGVRLREETSS NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgccgcgcagctcctggcctattacttcaccgagctgaaggatgaccaagtcaaa aagattgacaagtatctctatgccatgcggctctctgatgaaaccctgatagatatcatg actcgtttcaagaaggagatgaagaatggcctctcccgggattttaatccaacagccaca gtcaagatgttgccaacgtttgtaaggtccattcctgatggttcagaaaagggagatttc attgccctggatcttggcgggtcttcctttcgaattctgagggtacaagtgaatcacgag caaaaccagaatgttcacatggagtccgagatttatgacaccccggagaacatcgtgcat ggcagtggaagccagctttttgatcacgtggccgagtgcctgggagacttcatggagaaa aaaaaaatcaaggacaagaaattacctgtgggattcacgttttctttcccctgtcggcag tccaaaatagacgagggcatcctgataacctggacaaagaaatttaaagcgagcggagtg gagggaatggatgtggtgaagttgcttaacaaagccattaagaagcgcggggactacgac gccaacattgtggccgtggtgaacgacacggtggggaccatgatgacctgtggctacgat gaccagcagtgtgaagtcggcctcatcatcggcaccggcaccaacgcctgctacatggag gagctgaggcacattgacctggtggagggcgatgaggggaggatgtgcgtcaacacggag tggggggccttcggcgacgacgggtccctggaagacatccgcaccgagttcgaccgggag atagaccgtggctctctcaaccccgggaagcagctgtttgagaagatggtcagtggcatg tacttgggggagctggtgcgactgatcctggtcaagatggccaaggagagcctcttgttt gaagggcggatcaccccggagctgctcaccagggggaagttcaagaccagcgacgtgtca gccattgagaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga gtggagccatccgatgacgactgtatttcagtccagcacgtgtgtaccattgtctcattt cgctcggccaacctggtggctgcaacgctgggcgccatcttgaaccgccttcgagataac aagggcacacccaggctgcggaccacggttggtgtcgacgggtctctttacaagacgcac ccacagtattcccggcgtttccacaagactctgaggcgcttggtgcccgactccgatgtg cgcttcctcctctcggagagcggcagtggcaagggggcggccatggtcacggcggtggcc taccgcctggcggagcagcaccggcagatagaggagaccctggcccacttccgcctcacc aaggacatgctgctggaggtgaagaagaggatgcgggccgagatggatatgggcctgagg aagcagacacacgagaaggccgtggtcaagatgctgccctcctttgtccggagcactcca gacgggaccgagcatggtgacttcttggcccttgatcttggaggaacaaatttccgtgtc ctgctggtgaaaatccgcagtgggaaaaagagaacggtggaaatgcacaacaagatctat gccattcccattgaaatcatgcagggcactggggaagagctgtttgaccacatcgtctcc tgcatctctgacttcctggactacatggggatcaaaggccccaaaatgcctctgggcttc acgttctccttcccctgcaagcagacgagcctggatgcgggaatcttgatcacctggacc aagggttttaaggcaaccgactgcgtggggcacgacgtagcaaccttactaagggaagcg ataaaacggagagaggaattcgacctggacgtggtggctgtggtcaatgacacggtgggc accatgatgacctgtgcttacgaggagcctacctgcgaggttggactcattgtagggacc ggcagcaacgcctgctacatggaggaaatgaagaatgtcgagacgctggaggggaatgac gggcgcatgtgtatcaacatggagtggggtgcctttggggacaacgggtgtctagatgat atcagaacactctatgacagactggtggatgaatattctctaaacgctgggaaacaaagg tacgagaagatgattagcggtatgtacctgggtgagatcgtccgcaacatcttgatcgac ttcaccaagaagggcttcctcttccgagggcagatctctgagacgctgaagacccggggc atctttcagaccaaatacctttcccagattgagagtgaccgattagcgctgctccaggtc cgggccatcctccagcagctgggcctgaacagcacctgtgacgacagtatcctggtcaag actgtgtgcggggtggtgtccaagagggccgcgcagctgtgtggtgcgggcatggctgcc gtggtggataagatccgagagaacagagggctggaccacctcaacgtgactgtgggggtg gacggaacactctacaagcttcatccgcacttctccagaatcatgtaccaaaccgtgaag gaactgtcaccaaaatgtaacgtgtccttcctcctgtccgaagacggtagcggcaagggg gccgccctcatcacggcggtgggcgtccggctccgggaagagacgagcagctaa

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