Ursus arctos (brown bear): 113262931 Help Entry 113262931         CDS       T05909                                  Symbol PSEN2 Name (RefSeq) presenilin-2 isoform X1   KO K04522   presenilin 2 [EC:3.4.23.-] Organism uah  Ursus arctos (brown bear) Pathway uah04330   Notch signaling pathway uah04722   Neurotrophin signaling pathway uah05010   Alzheimer disease uah05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:uah00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     113262931 (PSEN2)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     113262931 (PSEN2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     113262931 (PSEN2)    05022 Pathways of neurodegeneration - multiple diseases     113262931 (PSEN2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uah01002]     113262931 (PSEN2) Peptidases and inhibitors [BR:uah01002]  Aspartic peptidases   Family A22: presenilin family    113262931 (PSEN2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Presenilin Motif Other DBs NCBI-GeneID:  113262931 NCBI-ProteinID:  XP_044243910 LinkDB All DBs Position Unknown AA seq 465 aa AA seqDB search MLTFMASDSEEEVCDERTSLMSAESPPPRCCQEARQGLEDGDNASQWRSQDSEDDLDEDA DRYMCSGVPGQPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLP YGGGREQSLQPAISLSIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKHR CYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKG PLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQE RNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPP LPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTL LLLAVFRKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt atgctcacattcatggcctctgacagtgaggaagaagtgtgtgacgagaggacgtccctg atgtcagccgagagccccccgccgcgctgctgccaggaggcccggcagggcctggaggac ggagacaatgcttcccagtggagaagccaggatagcgaggatgaccttgacgaggacgcg gaccgctacatgtgcagtggggtccccgggcagccgtcgggcctggaagaggagctgacc ctcaaatacggggcgaagcacgtgatcatgctgtttgtacccgtcaccctgtgcatgatc gtggtggtggccaccatcaagtccgtgcgcttctacacggagaagaacggccagctgccc tatggaggaggcagggagcagagtctgcagcccgccatctccctcagcatctacacacca ttcaccgaggacacgccctccgtgggccagcgcctgctcaactccgtgctcaacacgctc atcatgatcagcgtcatcgtggccatgaccatcttcctggtcgtgctctacaagcaccgc tgctacaagttcatccatggctggttgatcatgtcctccctgatgctgctgttcctcttt acctatatctacctcggggaagtgctcaagacctacaacgtggccatggactaccccacc ctgttcctgaccgtctggaactttggcgctgtggggatggtgtgcatccactggaaaggc cccctggtgctgcagcaggcctacctcatcatgatcagcgcgctcatggccttggtcttc atcaagtacctcccggagtggtctgcctgggtcattctgggcgccatctctgtgtatgat ctcgtggctgtgctgtgccccaaagggccgctgaggatgctggtggagactgcccaggag agaaacgagcccatatttcccgccctgatctactcctctgccatggtgtggacggtgggc atggccaagctggacccctcttcccagggagcccttcagctgccctacgaccccgagatg gaagaagactcctatgacagttttggggagccctcgtacccggaagtctttgagcccccc ctgcctggttacccaggggaggagctggaggaagaggaagaaaggggcgtgaagctcggc ctgggggacttcatcttctacagtgtgctggtgggcaaggcggcggccacgggcagcggg gactggaacaccacgctggcatgcttcgtggccatcctcattggtttgtgtctgaccctc ctgctgctggctgtgttcaggaaggcactgcccgccctccccatctccatcacgttcggg ctcatcttctacttctccacggacaacctggtgcgtccgttcatggacaccttggcttct catcagctctacatctga

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