Ursus arctos (brown bear): 113267083
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Entry
113267083 CDS
T05909
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah00061
Fatty acid biosynthesis
uah00620
Pyruvate metabolism
uah00640
Propanoate metabolism
uah01100
Metabolic pathways
uah04152
AMPK signaling pathway
uah04910
Insulin signaling pathway
uah04920
Adipocytokine signaling pathway
uah04922
Glucagon signaling pathway
uah04931
Insulin resistance
uah04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
113267083 (ACACB)
00640 Propanoate metabolism
113267083 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
113267083 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
113267083 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
113267083 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
113267083 (ACACB)
04922 Glucagon signaling pathway
113267083 (ACACB)
04920 Adipocytokine signaling pathway
113267083 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
113267083 (ACACB)
04931 Insulin resistance
113267083 (ACACB)
Enzymes [BR:
uah01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
113267083 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
113267083 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
113267083 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
Motif
Other DBs
NCBI-GeneID:
113267083
NCBI-ProteinID:
XP_026370851
LinkDB
All DBs
Position
Unknown
AA seq
2431 aa
AA seq
DB search
MMDSKQVTKSKSEGSCIPSQEPFPASDCSGEPPQKNGDRSPLPETPNQAEPTSHKGPKDA
CGQRTSRPPPHQNAPGNPCSSDDAPAALQANGTGTEGLRTPDTNGLSSPARPQGQRTRPL
SKEDEKQEHLKRQLMTNFVLGSFDDNSSDEDPGAGLFRESSRKSSRASLGTLSLEAALAV
GESESPVPAMRPSMSGLHLVKRGRELKKVDLHRDFTVASPAEFVTRFGGDRVIEKVLIAN
NGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNN
NYANVELVVDIAKRIPVQAVWAGWGHASENPKLPELLCKHEIAFLGPPSEAMWALGDKIA
STIVAQTLQIPTLPWSGSGLTVEWAEEDLQWGKRITVPEDVYNQGCVKDIDEGLQMAEKI
GFPLMIKASEGGGGKGIRKAESPEDFPILFRQVQSEIPGSPVFLMKLAEHARHLEVQILA
DQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAIPVVFEIMEQCAVRLAKTVGYVSTGTVE
YLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESP
WGVTPISFDTPANPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVA
AAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETERFQ
NNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPAA
SLLNIVDVELIYGGVKYILKVARQSLTMFVLIMNNCHIEIDAHRLSDGGLLLSYNGNSYT
TYMKEEFDSYRITIGNKTCVFEKENDPTVLRAPSAGKLLQYTVEDGGHVEAGSSYADMEV
MKMIMTLSVQESGRVKYMKRPGAMLEAGCVVARLELDDPSKVHPAKPFTGELPSQQTLPI
VGEKLHQVFHNVLENLTNVMSGYCLPEPIFSTKLKEWVQKLMMTLRHPSLPLLELQEIMT
SVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRRAEREVFFMN
TQSIVQLVQRYRSGTRGYMKAVVLDLLRRYLRVEHHFQQAHYDKCVINLRERLKPDMSQV
LDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEELTSILNELTQLSKSEHCKVALRARQV
LIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKV
VCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRMAVPISVTNPDLL
RHSTELFMDSGFSPLCQRMGAMVAFRRFEDFIRNFDEVISCFANVPREAPLFGKACTSLY
CEEDSKNPREEPIHILNVALQYADHLEDEELVPIFRKFVQSKKNILVDYGLRRITFLIAQ
EKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRSFDLTAVPCANHKMHLYLGAA
KVKEGAEVTDHRFFIRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRT
DCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTTGSAVPI
RLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRF
QAQSLGTTYVYDFPELFRQALFKLWGTPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNE
VGMVAFKMRFKTPEYPEGRDVIVISNDITFRIGSFGMGEDLLYLRASEMARAEGIPKIYL
AANSGACIGLAEEIKHIFQVAWVDPGDPHKGLKYLYLTPQDYTTISSLNSVHCRHIEEDG
ESRYVITDIIGKDSGVGIENLRGSGMIAGESSLAYDEIVTISLVTCRAVGIGAYLVRLGQ
RVIQVENSHIILTGVSALNKVLGREVYTSNNQLGGVQIMHYNGISHITVPDDFEGVCTIL
EWLSYMPKDNHSPVPIITPTDPIDREIGFFPTRAPYDPRWLLAGRPHPTLKGSWQSGFFD
HGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVVVPADPANLDSEAKIIQQAGQ
VWLPDSAYKTAQAIKDFNRERLPLMIFANWRGFSGGMKDMYDQMLKFGAYIVDSLRQYKQ
PVLIYIPPSAELRGGSWVVVDSSINPLCIEMYADKESRANILEPEGTVEIKYRKKDLIKT
MRRIDPAYKKLVEQLGMSGLSDKDRKDLEGQLKAREDLLLPIYHQVAVQFADLHDSPTCL
LEKGAISDILEWKTARSFLYWRLRRLLLEDQVKQEILRASGELSHVHIQSMLRRWFVETE
GAVKAYLWDNNQMVVQWLEQHWQGEDSLRSTVRENIRCLKRDSVLKAIRGLVQDNPEVAV
DCIVYMSQHISPAERAQVIHLLSTMDSAAST
NT seq
7296 nt
NT seq
+upstream
nt +downstream
nt
atgatggactctaagcaagtcaccaagagtaaatcagaagggagctgtatcccaagccag
gagccctttccagcctcagactgctcaggggagccaccacaaaaaaatggtgaccgcagc
cctctgccagagactcctaaccaggctgagccaacctcccacaaaggtcccaaagatgcc
tgtgggcaaagaacttccaggccacccccacaccagaatgccccaggaaacccctgttcc
tctgatgacgcccccgcagcgctccaagccaatgggacggggaccgaaggcctgaggacc
ccggataccaatggcctgtcatctccagccaggcctcagggccagcgaaccagaccgctc
tccaaagaagacgagaagcaggagcacctcaagaggcagctgatgaccaacttcgtcttg
ggctcctttgatgacaactcgtccgatgaggaccctggtgcgggcttgttccgagagtcc
tcccggaagagcagccgggccagcctggggaccctgtccctggaggccgctctggctgta
ggcgagtctgagagccccgtccccgctatgagacctagcatgtcgggactccacctggtg
aagaggggccgagaactgaagaaggtggacctgcacagagactttaccgtggcctcccca
gctgagtttgtcacgcgctttgggggggaccgggtcattgagaaggtgctcatcgccaac
aatggcatcgccgccgtgaagtgcatgcgctccatccgcaggtgggcctatgagatgttc
cgcaacgagcgggccatccggtttgtagtcatggtgaccccagaggacctgaaggccaat
gcagagtatatcaagatggcagatcagtatgtccctgtcccaggagggcccaacaacaac
aattatgccaacgtggagctggttgtggacattgccaagagaatccccgtgcaggcggtg
tgggctggctggggccatgcttctgaaaaccccaaactgccggagctcctgtgcaagcat
gagattgctttcttaggccctcccagtgaggccatgtgggccttgggagataagatcgcc
tccaccattgtagcccagacgctgcagatcccaacattgccctggagtggaagcggtctg
acggtggaatgggcagaagaggatctgcagtgggggaagaggatcactgtcccagaagat
gtttacaaccagggttgtgtgaaagatatagatgagggcttacagatggcagaaaaaatt
ggttttcccttgatgatcaaagcatctgaaggcggcggagggaaaggaatccggaaggca
gagagtcccgaggacttcccaatccttttcagacaagtgcagagtgagatccctggctcc
cccgtcttcctcatgaagctggccgagcatgcccgacacctggaggtccagatcctcgcc
gaccagtatgggaacgccgtgtccctgttcgggcgtgactgctccatccagcggcggcat
cagaagatcattgaggaggcgccggccaccatcgccataccggttgtgttcgagatcatg
gagcagtgtgccgtccgcctggccaagacggtgggctacgtgagcacggggacggtggag
tatctctacagccaggatggcagcttccacttcttggagctgaatccccgtctgcaggtg
gagcacccctgcacagagatgatcgccgacgtcaacctgcctgccgcccagttacagatt
gccatgggggtgcccctgcaccggctgaaggatatccggcttctgtatggagagtcgccg
tggggggtgacacccatttcgttcgacactcctgccaatcctccactcgcccgaggccat
gtcattgcggctagaatcaccagtgagaaccccgatgaggggtttaagccaagctctgga
acggttcaggagctgaatttccggagcaacaagaacgtgtggggttacttcagcgtagcg
gctgccggcggcttacacgagtttgctgattcccagttcgggcactgcttctcctgggga
gagaaccgggaagaggccatttcgaacatggtggtggctttgaaggaactgtccatccgg
ggcgacttcagaaccaccgtggagtatctcattaacctgctggagactgagcgcttccag
aacaatgacatcgacacaggctggttggattacctcatcgccgagaaagtgcaggcggag
aagccggatatcatgctcggggtggtgtgcggagccttgaacgtggccgatgcgatgttc
agaacttgcatgacggatttcttacactcgctggaaaggggccaggtccttcctgcagct
tctctgctgaacatcgtggatgtggaactaatttatggaggtgttaagtacattctcaag
gtggcccggcaatctctgaccatgttcgtcctcatcatgaacaactgtcacatcgagatc
gacgcccaccggctaagcgacggggggttgctgctgtcctataatggtaacagctatacc
acctacatgaaagaagagtttgacagttaccgtattaccatcggcaacaagacgtgtgtg
tttgagaaagagaacgatcccacggtcctgagagccccttcggctgggaagctgctgcag
tacacggtggaggacgggggccacgttgaggctgggagcagctacgctgacatggaggtg
atgaagatgatcatgaccttgagcgtgcaggaaagtggccgggtgaagtacatgaagcgc
ccgggggccatgctggaggcaggctgtgtggtggccaggctggagctcgatgacccttcc
aaagtgcacccggccaagccattcacaggagagctcccttcccagcaaactctgcccatc
gtgggagagaaactgcaccaggttttccacaatgtcctggaaaacctgaccaacgtcatg
agtggctactgtctgccggagcctatttttagcacaaagctgaaggagtgggtgcaaaag
ctcatgatgaccctccggcacccatcactgccgctgctggagctgcaggaaatcatgacc
agtgtgtccggccgtatccccgcccccgtggagaagtcggtccgcagggtgatggctcag
tacgccagcaacatcacctcggtgctgtgccagttccccagccagcagatagccaccatc
ctggactgccacgcggccaccctgcagcggagggccgaacgggaggtcttcttcatgaac
acccagagcattgtgcagctggtccagaggtaccgcagcgggacccgcggctacatgaag
gcggtggtgttggacctcctgcggagatacttgcgggtggagcatcatttccagcaagct
cactacgacaagtgcgtgataaacctcagggagcggctgaagccagacatgtcccaggtg
ctggactgcatcttctcccacgcgcaggtggccaagaagaaccagctggtgatcatgttg
attgatgagctctgtggcccagacccttccctgtcggaagagctgacctccatcctcaat
gagctcactcagctgagcaaaagcgagcattgcaaagtggccctcagagccagacaggtc
ctgattgcctcccacctcccgtcctacgagctgaggcacaaccaggtggagtccattttc
ctgtctgccatcgacatgtacggccaccagttctgcccagaaaacctcaagaaattaata
ctctcagaaacaaccatatttgatgtcctgcccactttcttctaccacgctaacaaagtc
gtctgcatggcatccttggaggtttacgtgcggaggggctatatcgcctatgagttaaac
agcttgcagcaccggcagctcccggacggcacctgcgtggtggaattccagttcatgctg
ccctcctcccacccaaacaggatggccgtgcccatcagcgtcaccaaccccgacctgctg
aggcacagcaccgagctcttcatggacagcggcttctccccactgtgccagcggatgggg
gccatggtcgccttcaggagattcgaggacttcataaggaacttcgacgaggtcatctcc
tgctttgccaacgtgccccgggaagcccccctcttcggcaaggcctgcacttccctgtac
tgtgaggaagacagcaagaaccccagagaagagccgatccacatcctgaatgtggccctc
cagtacgcggaccacctggaagatgaggagctggtgccgattttccggaagttcgtacag
tccaagaaaaacatccttgtggattacggactccgaagaatcacattcctgattgcccaa
gagaaagaatttcccaagtttttcacgttcagagcaagagacgagttcgcggaagatcgc
atttaccgtcatctggagcccgccctggccttccagctagagctcagccgcatgcgcagc
tttgacctgaccgccgtgccctgcgccaaccacaagatgcacctgtacctgggcgccgcc
aaagtgaaggagggcgcggaagtgacggaccaccgcttcttcatccgcgccatcatccgc
cactcagacctcgttacaaaggaagcctcctttgagtacctgcagaacgagggcgagcgt
ctgctcctggaggccatggacgagctggaggtggcattcaacaacacgagcgtacgcacc
gactgcaaccacatcttcctgaacttcgtgcccaccgtcatcatggacccctccaagatc
gaggagtccgtgcgttccatggttatgcgctatggcagccggctgtggaaactgcgcgtg
ctgcaggctgaggtcaagatcaacatccgccagaccaccactggcagcgctgttcccatc
cgcctgttcatcaccaatgagtcgggctactacctggacatcagcctctacaaagaagtc
accgaccccagatccggaaacatcatgtttcactcctttggcaacaagcagggaccccag
cacgggatgctgatcaacaccccgtatgtcaccaaggatctgcttcaggccaagcggttc
caggcccagtccctgggcaccacctatgtctacgacttcccggagctgttcagacaggct
ctctttaaactgtggggcaccccggacaagtaccccaaagacatcctgacatataccgaa
ctcgtgctggaccctcagggccagcttgtggagatgaaccgccttcctggaggaaatgag
gtgggcatggtggccttcaaaatgaggttcaagaccccagaatatccggaaggacgggac
gtgatcgtaatcagcaatgacatcacgttccgcatcggatccttcggcatgggagaagac
ctcttgtacctgcgggcctccgagatggcccgggcagagggtatccccaaaatctacctc
gcagccaacagcggggcctgtatcggccttgcagaggagatcaagcacatattccaggtg
gcttgggtggacccaggagacccccacaaaggacttaagtacttgtacctgacgccccaa
gactacaccacaatcagctccctgaactctgtccattgtaggcacatcgaagaagacggg
gaatccaggtatgtcatcacggatatcatcgggaaggacagtggtgtgggcatagagaat
ctcaggggctccggcatgatcgcgggggagtcctccctggcttacgacgagattgtcacc
atcagcttggtgacttgccgagccgtggggatcggggcctacttggtgaggctgggtcag
cgagtgatccaggtggagaactctcacatcatcctgacgggagtcagcgctctcaacaag
gtgctgggcagagaggtctacacgtccaacaaccagctgggcggcgtgcagatcatgcat
tacaatggcatctcccacatcactgtgccagatgacttcgagggcgtttgtaccatcctg
gagtggctgtcctatatgccaaaggataatcacagcccagtccccatcatcacacccacg
gaccccattgacagagaaattggattcttcccgacccgggctccctatgacccccggtgg
ctgctggcaggaaggcctcacccgactctgaagggatcctggcagagtggattctttgac
catggcagtttcaaggaaatcatggcgccctgggcccagaccgtggtgacaggacgagca
aggctaggggggatccctgttggcgtgatcgccgtggagacacggactgtggaggtggtg
gtgcctgcggaccctgccaacctggactcagaggccaagataatccagcaggcaggccag
gtgtggctcccagactccgcctacaagacggcccaggccatcaaggatttcaaccgagag
aggttgcccctgatgatctttgccaactggagggggttctccggtggcatgaaagacatg
tacgaccagatgctaaagttcggagcctacatcgtggacagtctcaggcagtacaagcag
cccgtcctgatctacatcccaccctccgcggagctccgggggggctcctgggtggtcgtg
gactcctccatcaaccccctgtgcatagaaatgtacgcggacaaggagagcagggcgaat
attctggagccggagggcacggtggagattaagtaccgaaagaaagatctgataaagacc
atgagaaggatcgacccagcttacaagaagctcgtggaacagctaggaatgtcggggctc
tccgacaaggaccgcaaggacctggagggccagctgaaggcccgggaggacctgctgctg
cccatctaccaccaggtggcggtgcagttcgccgacctccacgacagccccacctgcctg
ctggagaagggcgccatctccgacatcctggagtggaagaccgcgcgctccttcctatac
tggcgcctgcgccgcctcctgctggaggaccaggtcaagcaggagatcctgcgggccagc
ggcgagctgagccacgtgcacatccagtccatgctgcgccgctggttcgtggagacggag
ggcgccgtcaaggcctacctgtgggacaacaaccagatggtggtgcagtggctggaacag
cactggcagggggaggacagcctgcgctccactgtccgcgagaacatcaggtgcttgaag
cgagactccgtcctcaaggccatcagaggcctggttcaggacaaccctgaagtggccgtg
gactgcatcgtgtacatgagccagcacatcagcccggccgagcgggcccaagtcattcac
ctcctgtccaccatggacagcgcagcctccacctga
DBGET
integrated database retrieval system
