Ursus arctos (brown bear): 113268019
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Entry
113268019 CDS
T05909
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah05200
Pathways in cancer
uah05223
Non-small cell lung cancer
uah05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113268019 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113268019 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
113268019 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113268019 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
uah04090
]
113268019 (ALK)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
113268019 (ALK)
Protein kinases [BR:
uah01001
]
Receptor tyrosine kinases (RTK)
ALK family
113268019 (ALK)
CD molecules [BR:
uah04090
]
Proteins
113268019 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
MAM
Pkinase
ALK_LTK_GRD
Ldl_recept_a
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
113268019
NCBI-ProteinID:
XP_044235563
LinkDB
All DBs
Position
Unknown
AA seq
1624 aa
AA seq
DB search
MGSLGLLGLLLPLLSVAASGSGTGTGTETGTETGQLVSSPALGPALQPREPLSYSRLQRK
SLAVDFVVPSLFRVYARDLLLPPSSSLEPRAGRTEVHGSLALDCAPLLRLVGPPPWVSWT
ESASSPAPVQARTLTRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPEEATVGLLQFN
LSELFSWWIRHGEGRLRIRLMPEKKASEVGREGKLSAAIRASQPRLLFQILGTGRSSLES
PTSLPSPPPEPFAWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLGNQSWS
WRRVPSEEASQMDLLDGPETEHSKEMPRGSFLLLNTSANSKHTILSPWMRSSSEHCRLAV
SVHRHLQPSGRYVAQLLPHNEPGREILLVPTPGKHGWTVLQGRIGRPENPFRVALEYISS
GNRSLSAVDFFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHRDCAQGEDEGQ
LCSKLPAGFYCNFEDGFCGWTQGTLAPHNPRWQIRTLKDARGQDHRGHALLLSTTDVPTS
ESATVTSATFPAPMKNSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVATNEG
LSLWQWTVLPLVDVADRFWLQIVAWWGPGSRATVAFDNISISLDCYLTISGEDKMPQNTA
PKSRNLFERNPNKEPKVWENTRETPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYRNSNL
SVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKGDM
LYILVGQQGEDACPSTNRLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKM
KDGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLL
WSGKSLLEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEI
DGEDGVSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEGDECHMDPESHKVICFCDH
GTVLADDGVSCIVSPTPEPHLPLSLVLSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQ
MELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEV
YEGQVSGVPSDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQAL
PRFILLELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDI
AARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKT
DTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQP
EDRPNFAIILERIEYCTQDPDVIHTALPVEYGPLVEEEEKVPVRPQDPEGIPPLLVSPPQ
ANREEGREPAAPPPLPSASSGRAVKKPAAAEPSVRGARAPAVEGGHVNMAFSQSNPPSEL
HKVQGSRNKPTSLWNPTYGSWFTEKPARKTNPPAKKERHERGTPGREGSCAVAPPAAGGR
LPGASVLLEPSSLTASVKEVPLFRLRHFPCGTVNYGYQQQGLPLEAAAGAGRYGDSLLKS
RPAP
NT seq
4875 nt
NT seq
+upstream
nt +downstream
nt
atgggatcgttagggctcctagggctgctgctgccgctgctttcagtggcagcctcgggc
tccgggaccgggacagggacagagaccgggactgagactggccagctcgtgagctcaccc
gccctggggccggctctgcagcctcgggagccgctcagctactcacgtctgcagaggaag
agcctggcggtggactttgtggtgccctcgctcttccgcgtctatgcccgggacctgctg
ctgccgccttcgtcctcgttggagccgagggctggccggacggaggtgcatggctcgctg
gctctagactgcgccccactacttcggctggtggggccaccgccctgggtctcctggaca
gaaagcgccagctcgccagccccggtccaggcacggacgctgaccagggtgctgaagggc
ggctcggttcgcaagctccggcgcgccaagcagctggtgctggagctgggagaggaggct
atccttgaggggtgcgtcgggcccccagaggaggcaactgtgggactgctccagttcaac
cttagcgagctgttcagctggtggattcgccatggcgaggggcggctgaggatccgcctg
atgccggagaagaaggcttcggaagtgggcagagagggaaagctgtccgcggcgatccgc
gcctcccagccccgccttctcttccagatcttggggaccggtcgcagctccttggagtca
ccgacaagcctgccttctcctcctcctgagcctttcgcatggaatctgacgtggataatg
aaagattccttccctttcctctctcatcgtagtcgatatggcctggagtgcagcttcgat
ttcccctgcgagctggagtactccccgccccttcacgaccttggcaaccagagctggtcc
tggcgccgcgtcccctctgaggaggcctcccagatggacctgttggatgggccggagaca
gagcactccaaggagatgccccgaggctccttcctcctcctcaacacctcagccaactcc
aagcacaccatcctgagtccgtggatgaggagcagcagtgagcactgcaggctggctgtc
tccgtgcacaggcatctacagccttctgggaggtatgtcgcccagctgctgccccacaac
gagcctggaagagagatcctcctggtacctaccccaggaaagcatggatggacagtgctt
cagggaagaattgggcgcccagagaatcccttccgagtggccctggaatacatctcaagt
ggaaaccgaagcttgtctgcagtggacttctttgccctgaaaaactgcagcgaaggaaca
tccccgggctccaagatggctttgcagagttccttcacctgctggaacgggaccgtcctc
cagctcgggcaggcctgtgacttccaccgggactgcgcccagggagaagacgagggccag
ctgtgcagtaagctccctgctggtttttactgcaacttcgaggatggcttctgtggctgg
acccagggcacactcgcaccccacaacccccggtggcagatcaggaccctgaaggatgcc
cggggccaggaccaccgaggccacgccctattgctcagcaccactgacgtccctacttct
gaaagtgctactgtgaccagcgctacgttccccgccccgatgaagaactctccgtgtgag
ctccgaatgtcctggctcatccgtggagtcttgcggggaaatgtctccttggtgctagtg
gagaacaaaactgggaaggaacaaggcagaatggtctggcatgttgccaccaatgaaggc
ttgagcctgtggcagtggacggtgctgcctcttgtcgatgtggctgacaggttctggctg
cagattgttgcgtggtggggcccaggatccagagccaccgtggcttttgacaatatctcc
atcagcctggactgctacctcaccatcagcggagaggacaagatgccacagaatacagcc
cccaaatcaagaaatctatttgagagaaacccaaacaaggagccaaaagtctgggaaaac
acaagagagacccccatctttgaccccacagttcactggctgttcaccacgtgcggggcc
agcgggccccatggccccacacaggcccagtgtaacaacgcctaccggaattccaacctg
agcgtggtggtggggagcgagggccccctgaaaggcatccagacctggaaggtgccagcc
accgacacctacagcatctcaggctacggagctgctggtgggaaaggcgggaagaacacc
atgatgcggtcccacggcgtgtctgtgctgggcatcttcaacctggagaagggcgacatg
ctgtatatcctagttggacaacagggggaagacgcctgccccagcacaaaccgattaatc
cagaaagtgtgcattggtgagaacaacgtgatagaagaagagatccgtgtgaacaggagt
gtgcatgagtgggcaggagggggtggaggtggaggcggagccacgtacgtgtttaagatg
aaggatggcgtgccagtgcccctgatcattgcagccggcggtggcggcagggcctatggg
gccaagacagacacgttccacccagagagactggagaataactcctcggttctggggctg
aacggcaactctggagccgcaggtggcggaggtggctggaatgataacacttccttgctc
tggtctggaaagtctttgctggagggtgccaccggaggacattcctgcccccaggccatg
aagaagtgggggtgggagacaagagggggtttcggagggggtggaggggggtgctcctca
ggtggaggaggcggaggatatataggcggcaacgcggcctcaaacaatgaccccgagatc
gacggggaggacggggtctctttcatcagtccgctgggcatcctgtatacccccgcttta
aaagtgatggagggccatggggaagtgaatattaagcattatctgaactgcagccactgt
gagggagacgagtgccacatggaccccgagagccacaaggtcatctgcttctgtgaccac
gggacagtgctggctgacgatggcgtctcctgcattgtgtcccccaccccagagccccac
ctgccgctctcgctggtcctgtctgtcgtgacctcagccctcgtggccgccctggtcctg
gctttctccggcatcatgattgtgtaccgccggaagcaccaggagctgcaagccatgcag
atggagctgcagagccctgagtacaagctgagcaagctccgcacctcgaccatcatgacc
gactacaaccccaactactgcttcgctggcaagacctcgtccatcagcgacctgaaggag
gtgcctcggaaaaacatcaccctcatccggggactgggccacggtgcattcggggaggtg
tatgaaggtcaggtgtccggagtgcccagcgacccgagccccctgcaagtggctgtaaag
acgctgcctgaagtgtgttctgaacaggacgaactggatttcctcatggaagccctgata
atcagcaaattcaaccaccagaacatcgtgcgctgtattggggtgagtctgcaagccctg
ccccgatttatcctgctggagctcatggcaggaggagacctcaagtccttcctccgggag
acccgccctcgcccgaaccagccctcctccctggccatgctggaccttctgcacgtggct
cgggacatcgcctgtggctgtcagtatttggaggaaaatcacttcatccaccgagacatt
gctgccagaaactgcctcttgacctgtccgggccctggcagagtggccaagattggagac
tttggaatggcccgggacatctacagagcgagctactaccgaaaaggaggctgcgccatg
ctgcccgtcaaatggatgcctccagaggctttcatggaagggatattcacttctaaaacg
gacacatggtccttcggcgtgctgctgtgggaaatattttctcttggatacatgccgtac
cccagcaaaagcaaccaagaagttctggagttcgtcaccagcggaggacggatggatcca
cctaagaactgccctgggcccgtataccggataatgacccagtgctggcaacatcagcct
gaagacaggcccaactttgccataattttggagaggatcgaatactgcacccaggacccg
gatgtgatccacacggctctgcccgtagagtacggcccgctggtggaggaggaggagaag
gtgcccgtgaggccccaagacccggaggggatcccgccgctcctcgtctctcccccccag
gctaaccgcgaggaggggcgcgagccggctgccccgccgcccctgccttccgcgtcctcc
ggcagagccgtgaagaagcccgcggcggccgagccgtctgttcgaggcgcgcgggcgccg
gccgtggaaggaggacacgtgaacatggcgttctcccagtccaacccgccttcagagctg
cacaaggtccagggatccaggaacaagccgaccagcctgtggaaccccacgtacggctcg
tggtttacggagaaacccgccagaaagaccaatcctccagccaagaaggagcgccacgag
aggggcaccccggggcgggaggggagctgtgctgtcgcccctcccgcggcgggcggccgg
ctgccgggagcgtctgtgctgctggagccgtcctcgctgacggccagcgtgaaggaggtg
cccctgttccggctgcgccacttcccgtgcggcaccgtcaactacggctaccagcagcag
ggcctgccgctggaggccgccgccggggccgggcgctacggggacagcctgctgaagagc
cggcccgcgccctga
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integrated database retrieval system
