Ursus americanus (American black bear): 123777895
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Entry
123777895 CDS
T07931
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04010
MAPK signaling pathway
uar04020
Calcium signaling pathway
uar04022
cGMP-PKG signaling pathway
uar04024
cAMP signaling pathway
uar04260
Cardiac muscle contraction
uar04261
Adrenergic signaling in cardiomyocytes
uar04270
Vascular smooth muscle contraction
uar04713
Circadian entrainment
uar04720
Long-term potentiation
uar04723
Retrograde endocannabinoid signaling
uar04724
Glutamatergic synapse
uar04725
Cholinergic synapse
uar04726
Serotonergic synapse
uar04727
GABAergic synapse
uar04728
Dopaminergic synapse
uar04742
Taste transduction
uar04911
Insulin secretion
uar04912
GnRH signaling pathway
uar04921
Oxytocin signaling pathway
uar04924
Renin secretion
uar04925
Aldosterone synthesis and secretion
uar04927
Cortisol synthesis and secretion
uar04929
GnRH secretion
uar04930
Type II diabetes mellitus
uar04934
Cushing syndrome
uar04935
Growth hormone synthesis, secretion and action
uar05010
Alzheimer disease
uar05020
Prion disease
uar05022
Pathways of neurodegeneration - multiple diseases
uar05031
Amphetamine addiction
uar05207
Chemical carcinogenesis - receptor activation
uar05410
Hypertrophic cardiomyopathy
uar05412
Arrhythmogenic right ventricular cardiomyopathy
uar05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123777895 (CACNA1C)
04020 Calcium signaling pathway
123777895 (CACNA1C)
04024 cAMP signaling pathway
123777895 (CACNA1C)
04022 cGMP-PKG signaling pathway
123777895 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
123777895 (CACNA1C)
04929 GnRH secretion
123777895 (CACNA1C)
04912 GnRH signaling pathway
123777895 (CACNA1C)
04921 Oxytocin signaling pathway
123777895 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
123777895 (CACNA1C)
04924 Renin secretion
123777895 (CACNA1C)
04925 Aldosterone synthesis and secretion
123777895 (CACNA1C)
04927 Cortisol synthesis and secretion
123777895 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
123777895 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
123777895 (CACNA1C)
04270 Vascular smooth muscle contraction
123777895 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
123777895 (CACNA1C)
04727 GABAergic synapse
123777895 (CACNA1C)
04725 Cholinergic synapse
123777895 (CACNA1C)
04728 Dopaminergic synapse
123777895 (CACNA1C)
04726 Serotonergic synapse
123777895 (CACNA1C)
04720 Long-term potentiation
123777895 (CACNA1C)
04723 Retrograde endocannabinoid signaling
123777895 (CACNA1C)
09157 Sensory system
04742 Taste transduction
123777895 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
123777895 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
123777895 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
123777895 (CACNA1C)
05020 Prion disease
123777895 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
123777895 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
123777895 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
123777895 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
123777895 (CACNA1C)
05414 Dilated cardiomyopathy
123777895 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
123777895 (CACNA1C)
04934 Cushing syndrome
123777895 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
uar04040
]
123777895 (CACNA1C)
Ion channels [BR:
uar04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
123777895 (CACNA1C)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Etmic-2
Motif
Other DBs
NCBI-GeneID:
123777895
NCBI-ProteinID:
XP_045630881
LinkDB
All DBs
Position
Unknown
AA seq
2164 aa
AA seq
DB search
MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNSTPAGLLDQKKGKFAWF
SHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRK
CRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMY
SLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNS
LSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSL
LTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNL
ADAESLTSAQKEEEEEKERKKLARTASPEKKQEVVEKPAVEETKEEKIELKSITADGESP
PTTKINMDDLQPNENEDKCPYPNPENTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPE
ASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYF
DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKI
LRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLY
TCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEG
WPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQE
YKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICL
AMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSII
DVILSETNPAEHTQCSPFMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKS
FQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGE
AWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIM
DNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPH
RVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRT
SMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLR
TLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVTYYQSDGRS
AFPQTFTTQRPLHINKAANSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALG
RFPRPAGYPSAVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQIAMVCQEEVSQDET
YDVKMSEDTEYCSEPSLISTEMLSYQDDENRQLTPPEEDKRDVRQSPKRGFLRSASLGRR
ASFHLECLKRQKNQGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPSTFPRPCATPP
ATPGSRGWPPQPIPTLRLEGAESSEKLNSSFPSIHCSSWSGEPTPCGAGSSAIRRARPVS
LTVPSQAGARGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEME
NAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAGGQEGETCAAALACRKSEEELQDSRAH
AGGL
NT seq
6495 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgagaacacgaggatgtacattccagaggaaaatcatcaaggttctaactat
gggagcccgcgcccagctcatgccaacatgaatgccaatgccgctgcggggctcgcccct
gagcacatccctacgccgggggcagccctgtcctggcaggcggctatcgacgcggcccgg
caggccaagctgatgggcagcgccggcaacgcgaccatctccacggtcagctccacgcag
cggaagcggcagcagtatgggaaacccaagaagcagggcagcacgactgccacgcgcccg
ccccgcgccctgctctgcctgactctgaagaaccccatccggagggcatgcatcagcatc
gtcgaatggaaaccatttgaaataattattttactgactatttttgccaattgtgtggcc
ttagcgatctatattccctttccagaagatgactccaacgccaccaattccaacctggaa
cgagtggaatatctctttctcataatttttactgtggaagcatttttaaaagtaatagcc
tatggacttctctttcatcccaacgcttacctccgcaatggttggaatttactagatttt
ataattgtggttgtagggctttttagtgcaattttagaacaagcaaccaaagctgacggg
gcaaatgctctgggagggaaaggagctggatttgacgtgaaggcactgagggcattccgc
gtgctgcgccccttgcgcctggtatctggagtcccaagtctccaggtggttctgaattcc
attatcaaggccatggtgcccctgctgcatattgctctgttagtgctgtttgtaatcatc
atctatgccatcattggcctggagctcttcatggggaagatgcataagacctgctacaac
caggagggcatagcagatgttccagcagaagatgatccttccccttgtgctctggagaca
ggccatgggcgtcagtgtcagaacggcactgtgtgcaagcctgggtgggacgggcccaag
cacggcatcaccaacttcgacaattttgccttcgccatgttgacagtgttccagtgcatc
accatggagggctggacagacgtcctgtactgggtcaatgatgccgtaggaagggactgg
ccctggatctattttgttacactaatcatcatagggtcattttttgtacttaacttggtt
ctcggtgttcttagcggagagttctccaaagagagggagaaggccaaggctcggggagat
ttccagaaacttcgagagaagcagcagctggaagaggatctgaagggctacctggactgg
atcacccaggcagaggacattgaccctgagaatgaggatgaaggcatggatgaggagaag
ccccgaaacagcactccagcgggcttgcttgatcagaagaaagggaagtttgcttggttt
agtcactccacagaaacccatgtgagtatgcccacaagcgagaccgagtctgtcaacacc
gaaaacgtggctggaggtgacatcgagggagagaactgcggggccaggctggcccaccgg
atttccaaatcaaagttcagccgctactggcgccgctggaatcggttctgcagaagaaag
tgtcgtgccgcagtcaagtctaatgtcttctactggcttgtgatcttcctggtgttcctc
aacactctcaccattgcctcggaacactacaaccagccccactggctcacggaggtgcaa
gacacggccaacaaggcgctgctggcccttttcactgcagagatgctgctgaagatgtac
agcctgggcctgcaggcctacttcgtgtccctcttcaaccgcttcgactgtttcatcgtg
tgtggtggcatcctggagaccatcctggtggagaccaagatcatgtctcccttgggcatc
tctgtgttgagatgtgtccggctactgcggatatttaaaatcacaaggtactggaactcc
ttaagcaacctggtggcatccttgctgaattctgtgcgctccattgcctccctactgctg
ctcctcttcctcttcatcatcatcttctccctcctggggatgcagctctttggaggaaag
ttcaactttgatgaaatgcagacccggaggagcacatttgataactttccccagtccctc
ctcaccgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatgggatc
atggcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatcctc
ttcatctgtggaaactatatcctactgaatgtgttcttggccattgctgtggacaacctg
gctgatgctgagagcctcacatctgcccaaaaggaggaagaagaagagaaggagagaaag
aagctggccaggactgccagcccagagaagaaacaagaggtggtggagaagccagcagta
gaggagaccaaggaggagaaaattgaactgaaatccattacagctgatggagagtcccca
cccaccaccaagatcaacatggatgacctccagcccaatgaaaatgaggataagtgcccc
taccccaacccagaaaatacaggagaagaggatgaggaggagcctgagatgcctgtgggc
ccccgcccacgaccactctctgagctgcaccttaaggaaaaggcagtgcccatgccagaa
gccagtgcgtttttcatcttcagccccaacaacagatttcgcctccagtgtcaccgcatt
gtcaatgacacgatcttcaccaacctgatcctcttcttcattctgcttagcagcatttcc
ctggcagctgaggaccccgtccagcacacctccttcaggaaccatattctgttttatttt
gacattgttttcactaccattttcaccattgaaattgctctgaagatgactgcttatggg
gctttcctacacaagggctctttttgccgaaactacttcaacatcttggacctgctggtg
gtcagcgtgtccctcatttcctttggcatccagtcaagtgcaatcaacgtggtgaagatc
ttacgagtcctgcgagtcctcagacccctaagggccatcaacagggccaaggggctgaag
cacgtggttcagtgcgtgttcgtcgccatccggaccatcgggaacatcgtcattgtcacc
acgctactccagttcatgttcgcctgcatcggggtccagcttttcaagggaaagctctac
acctgctcagatagttccaaacagactgaggcggaatgcaagggtaactacatcacatac
aaggacggggaggtcgaccaccccatcatccaaccccgcagctgggagaacagcaagttt
gactttgacaatgttctggcagccatgatggccctctttaccgtctctacctttgagggg
tggccagagctgctgtaccgctccatcgactcccacacagaagacaagggccccatctac
aactaccgtgtggagatctccatctttttcatcatctacatcatcatcattgccttcttc
atgatgaacatcttcgtgggtttcgtcatcgtcaccttccaggagcagggggagcaggaa
tacaagaactgtgagctggacaagaaccagcgacagtgcgtggaatatgccctcaaggcc
cggcccctacggaggtacatccccaagaaccagcaccagtacaaagtgtggtacgtggtc
aactccacctactttgaatacctgatgttcgtcctcatcctgctcaacaccatctgcttg
gccatgcagcactatggccagagctgcctcttcaaaattgccatgaacatcctcaacatg
ctcttcactggcctcttcaccgtggagatgattctgaagctcattgccttcaaacccaag
ggttactttagtgatccctggaatgtttttgacttcctcatcgtaattggcagcataatt
gacgtcattctcagtgaaactaatccagctgaacatacccaatgctctccctttatgaac
gcagaggagaactcccgcatctccatcaccttcttccgcctcttccgggtcatgcgcctg
gtcaagctgctgagccgcggagagggcatccggaccctgctgtggaccttcatcaaatcc
ttccaggccctgccctatgtggcccttctgatagtgatgctgttcttcatctatgcggtg
attgggatgcaggtgtttgggaaaattgccctgaatgacaccacagagatcaaccggaac
aacaacttccagaccttcccccaagctgtgctgcttctcttcaggtgtgccaccggggag
gcatggcaggacatcatgctggcctgcatgccagggaagaagtgtgcccccgaatcagag
cccagcaacagcacagaaggcgaaacaccctgtggcagcagcttcgcggtcttctacttc
atcagcttctacatgctttgtgccttcctgatcatcaacctctttgtagctgtcatcatg
gacaactttgactacctgacaagggactggtcaattcttggtccccatcatctggatgaa
tttaaaagaatctgggcagagtatgatcctgaagccaagggtcgtatcaagcacctagat
gtggtgaccctgcttcgacggatccagcccccactgggttttgggaagctgtgccctcac
cgcgtggcttgcaaacgcctggtctccatgaacatgcctctgaacagtgatgggacagtc
atgttcaatgccaccctgtttgccctggtccggacagccctgcgaatcaaaacagaaggg
aacctagaacaagccaatgaggagctgcgggccataatcaagaagatatggaagcggacc
agcatgaagctgttggaccaagtggtgcccccagcaggtgatgacgaggtcacagttggc
aagttttatgctactttcctgatccaagagtatttccggaaattcaagaagcgcaaagag
cagggcctagtgggcaagccctcccagaggaacgccctgtccctacaggccggcttgcgc
acgctgcatgacatcgggcctgagatccgacgggccatctctggggatctgacggctgag
gaggagctggacaaggccatgaaggaggctgtgtctgctgcctccgaagacgacatcttc
aggagggccggtggcctgttcggcaaccacgtcacctactaccaaagcgacggccggagc
gccttcccccagaccttcaccacccagcgcccactgcacatcaacaaggcggctaacagc
caaggcgacaccgagtcgccatcccacgagaaactggtggactccactttcacccccagc
agctactcgtccactggctccaacgccaacatcaacaatgccaacaacactgccctgggc
cgcttcccccgccccgctggttaccccagcgcggtcagcaccgtggagggccatgggccc
cccttgtctcctgccgtccgggtacaggaggcagcatggaagctcagctccaagaggtgc
cactcccgggagagccagatagccatggtgtgtcaggaggaggtctctcaggacgagacc
tatgacgtgaagatgagcgaagacaccgagtactgcagcgagcccagcctgatctccaca
gagatgctctcctaccaggatgatgaaaatcggcaattaacaccacctgaggaggacaag
agagacgtccggcaatctccaaagaggggtttcctccgctctgcctcactaggtcgaagg
gcctccttccacctggaatgtctgaagcgacagaagaatcaagggggagacatctctcag
aagacagtcctgcccttgcatctggttcaccatcaggcattggcagtggcgggcctgagc
cccctcctccagagaagccattcccccagcacgttccccaggccatgtgccaccccccca
gccacgccgggcagccgaggctggcccccacagccgatccccaccctgcggctggagggg
gccgagtccagcgagaaactcaacagcagcttcccgtccatccactgcagctcttggtcc
ggggagcccacgccctgcggtgcgggcagcagcgccatccggagagcccggccggtgtcc
ctcactgtgcccagccaggctggggcccggggcaggcagttccacggcagcgccagcagc
ctggtggaagcggtcttgatttcagaaggactggggcagtttgctcaagatcccaagttt
atcgaggtcacaacccaggagctggctgacgcctgtgacatgaccatagaagagatggag
aacgccgccgacaacatcctcagtgggggcgcccagcagagccccaacggcaccctacta
ccttttgttaactgcagggacccagggcaggacagagcggggggccaagagggcgagacc
tgcgccgcggctctggcgtgtcggaaaagcgaggaggagctccaggacagcagagcccac
gccggcggcctgtag
DBGET
integrated database retrieval system
