Ursus americanus (American black bear): 123777917
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Entry
123777917 CDS
T07931
Symbol
FASN
Name
(RefSeq) fatty acid synthase
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00061
Fatty acid biosynthesis
uar01100
Metabolic pathways
uar01212
Fatty acid metabolism
uar04152
AMPK signaling pathway
uar04910
Insulin signaling pathway
uar04936
Alcoholic liver disease
Module
uar_M00082
Fatty acid biosynthesis, initiation
uar_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
123777917 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
123777917 (FASN)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123777917 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123777917 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
uar01004
]
123777917 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
uar04147
]
123777917 (FASN)
Enzymes [BR:
uar01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
123777917 (FASN)
Lipid biosynthesis proteins [BR:
uar01004
]
Fatty acid synthase
Animal type
123777917 (FASN)
Exosome [BR:
uar04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
123777917 (FASN)
Exosomal proteins of breast milk
123777917 (FASN)
Exosomal proteins of colorectal cancer cells
123777917 (FASN)
Exosomal proteins of bladder cancer cells
123777917 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
KAsynt_C_assoc
Ketoacyl-synt_C
FAS_pseudo-KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
Methyltransf_12
PP-binding
adh_short
PS-DH
Methyltransf_11
Methyltransf_23
DUF7080
Thiolase_N
Methyltransf_25
Methyltransf_31
Motif
Other DBs
NCBI-GeneID:
123777917
NCBI-ProteinID:
XP_045630915
LinkDB
All DBs
Position
Unknown
AA seq
2518 aa
AA seq
DB search
MEEVVIAGMSGKLPESDNLQEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSKF
DASFFGVHPKQAHTMDPQLRLLLEVTYEAILDGGINPASLRGTHTGVWVGVSGSEASEAL
SRDPETLLGYSMVGCQRAMMANRISFFFDFKGPSVALDTACSSSLVALQNAYQAIRHGEC
PCAIVGGINILLKPNTSVQFLKLGMLSPEGSCKSFDESGNGYCRSEAVVVMLLTKKSLAR
RVYATILNAGINTDGCKEQGVTFPSGEAQEQLIRSLYEPAGLAPESLEYIEAHGTGTKVG
DPQELNGIDRALCTTRRDPLLIGSTKSNMGHPEPASGLAALAKVLLSLENGVWAPNLHFH
SPNPEIPALREGRLQVVDRPLPVRGGNVGINSFGFGGSNVHVILRPNLQPPSPSTPHVTL
PRLLQASGRTPEAVRCLLEQGHQHGRDAAFVSMLNDIAASPPSAMPFRGYTVLGAEDSSL
ELQEVQQPPNGRRPLWFICSGMGTQWRGMGSSLMRLDSFRDSILRSDEAVKPLGLQVSKL
LLSADETTFDDLIHSFVCLTAIQIALIDLLTSMDLRPDGIIGHSLGEVACGYADGCLSQE
EAVLTAYWRGQCIKEANIPPGAMAAVGLSWEECKQRCPPGIVPACHNSEDTVTISGPQAE
MAAFMEQLKQEGVFAKEVRTGGMAFHSYFMESIAPTLLRALKKVIREPKPRSARWLSTSI
PEAQWKGSLARMCSAEYSVNNLVSPVLFQEALCHVPEHAVVLEIAPHALLQAVLKRGLKA
SCAIIPLMKRDHRDNLEFFLRNVGRLHLLGIDANPNGLFPPVEFPVPRGTPLISPHIKWD
HSQVWDVPAAGDFPSGSSGSSTATVYNIDTSPESPDHYLVDHCIDGRVLFPATGYLCLAW
KVLARALSQNMEDVPVVFEDVTLHQATILPKSGTVALEVRLLEASRTFEVSQNGNLIVSG
KVYQWEDPDPKLFDRGDGPDPADPTDPTATFRLSQGDVYKELRLRGYDYGPYFQGILETN
LEGNTGQLLWKDNWVTFLDTMLQMSILGIVQRTLRLPTRITSIHIDPATHRQKVYSLKGQ
AQVADVVVSSCLNSTAAGGVLISGLHASVAPRRQQEQLAPSLEKFCFTPHVEGGLLAGNA
ALQEELQLCRGLAQALQTKVAQQGLKMVVPGLDGAQVPREPPQQGLPQLLAAACQLQLNG
SLQLELDQLLAQQRPLLHDDPLLSGLLDSPALKACVDTALENLTSPRMYIVEVLAGDGRL
YSRVPALLNTQPMLQLDYTATDRHPQALEAAQAKLQEYGMAQGQWDPADPAPSSLGAADL
LVCNCAVAPLRDPATALGNMAAALKEGGFLLLHVLLRGHPLGETVAFLTCPEQRGPQSLL
SQDEWEGLFAAASLHLAALKRSFYGSALFLLRRPAPRDSPVFLPVEDTSFRWVDSLKNVM
ADNSSRPVWLTAVSCATSGVVGMVNCLRREPGGHRIRCILVSNLSSTSPVPKMDPSSSEL
QKVLQGDLVMNVYRDGSWGAFRHFPLERGLPEEQTEHAFVNVLTRGDLSSIRWVCSPLRH
VQPTEPGVYLCTVNYASLNFRDIMLATGKLSPDAIPGKWAARECMLGMEFSGRDASGKRV
MGLVPAEGLATSVVLSQDFLWDVPSSWTLEEAASVPVVYTTAYYSLVVRGRVRRGETVLI
HSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLSDASFANSRDTSFEQHVL
RHTAGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHQLGMAIFLKNVAFHG
ILLDSLFDEASSEWREVAGLLQAGIRDGVVQPLKCTTFPKHQVEDAFRYMAQGKHIGKVV
VQVLEEQEAVPQVTRPLLMTAASKTFCPAHKSYVITGGLGGFGLELAQWLVLRGAQKLVL
TSRSGIRTGYQAKQVREWRRQGVQVLVSTSNASSLDGAQSLIAEATQLGPVGGVFNLAMV
LRDAMLENQTPEFFQDVSKPKASGTVNLDRVTRAACPELDYFVAFSSVSCGRGNAGQANY
GFANSTMERVCEKRRHDGLPGLAVQWGAIGDVGVVLETMGSNDTVIGGTLPQRITSCLEV
LDLFLNQPHPVLSSFVLAEKKATAQGDGSTHQDLMKAVAHILGIRDLATVNLDSTLADLG
LDSLMGVEVRQMLEREHDLVLSMRDIRQLTLRKLQELSSKASTADELGAPTPKDNSSTSQ
QAQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSVTVFHSLAAKLSIPTYGLQC
TRAAPLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCFQLQTQQSPAPTHNS
LFLFDGSHTYVLAYTQSYRAKMTRGCEAEAEAEAMCFFVQQFIDMEHDRVLEALLPLGGL
EERVAAAVDLIKRSHTGLDRRELSFAARSFYYKLRAAEEYAPQATYHGNVTLLRAKTSSV
YGEGLGADYSLSQVCDGKVSVHVIEGDHRTLLEGSGLDSIVSIIHGSLAEPRVSVREG
NT seq
7557 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtggtgattgctggcatgtccgggaagctgcccgagtcggacaatctgcag
gagttctgggccaatctcatcggcggtgtagacatggtgacagacgatgacaggaggtgg
aaggcaggactctacggcctgcccaggcggtccggcaagctgaaggacctatccaagttc
gacgcgtccttcttcggggtccacccaaagcaggctcacaccatggacccccagctacgc
ttgctgctggaggtcacctacgaggccatcttggacggaggcatcaacccagcgtcactc
cgagggacacacaccggtgtctgggtgggcgtgagcggctctgaggcctcagaggccctt
agtcgagacccggagactctattgggctacagcatggtgggctgccagcgtgccatgatg
gccaaccgtatttccttcttctttgattttaaagggcccagcgtcgctctggacacggcc
tgctcctccagcctggtggctctgcagaacgcctaccaggccatccgccacggggagtgc
ccctgcgccatcgtgggcggcatcaacatcctgctgaaacccaacacctctgtgcagttc
ctgaagctgggcatgctgagccccgagggcagctgcaagtccttcgatgaatctgggaac
ggttactgccgctcggaggccgtggtggtcatgctgctgaccaagaagtccctggcccgg
cgcgtgtacgccaccatcctgaacgccggcatcaacaccgatggctgcaaggagcaaggt
gtgaccttcccctccggggaggcacaggagcagctcatccgctccctgtatgagccagct
gggctggccccagagtccctcgagtatatcgaagcccatggtacgggcaccaaggtcggc
gacccccaggagctgaacggcattgaccgagccctttgcaccacccgccgggaccccttg
ctgatcgggtccacgaagtcgaacatggggcacccagagcccgcctcggggctcgcggcg
ctggccaaggtgctgctgtccctggaaaacggggtctgggcccccaacctacacttccac
agcccgaaccctgagatccctgcccttcgggaagggcggctgcaggtggtggaccggccc
ctgcccgtccgtggaggcaacgtgggtatcaattcctttggcttcggcggctccaatgtg
cacgtcatcctcaggcccaatttgcagccaccctcgccgtccaccccgcacgtcaccctg
ccccgtctgctgcaggccagcgggcgcaccccagaggccgtgcggtgcctgctggaacag
ggccaccagcacggccgggacgcggccttcgtgagcatgctcaatgacattgcggccagc
ccccccagcgccatgccgttccggggctacacggtgctgggagccgaggacagcagtctg
gagctgcaggaggttcagcagccgcccaacggacggcgtccactctggttcatctgctct
gggatgggcacacagtggcgcgggatggggtcgagcctcatgcgcctggacagcttccga
gactccatcctgcgctccgacgaggccgtgaagcccttgggtctgcaggtatccaagctg
ctgctgagcgcagacgagaccaccttcgacgacctcatccactcgttcgtgtgcctcacc
gccatccagatcgccctcatagacctgctgacctccatggacctgcggcccgacggcatc
atcgggcactccctgggggaggtggcctgcggctacgcagacggctgcctttctcaggag
gaggccgtcctcaccgcctactggaggggccagtgcatcaaggaggccaacatcccgcca
ggggccatggcggccgtgggcttgtcctgggaggagtgtaaacagcgctgtccccctggc
attgtgcccgcgtgccacaactccgaggacacggtgaccatctcaggacctcaggctgag
atggctgcatttatggagcagctgaagcaggagggtgtgtttgccaaggaggtgcggacg
ggcggcatggccttccactcctacttcatggagtccatcgcacccacgctgctgcgggcg
ctcaagaaggtgatccgggagccgaagccccgctcggcgcgctggctcagcacctccatc
cctgaggcccagtggaagggcagcctggcccgcatgtgctcggcggaatacagcgtcaac
aacctcgtgagccccgtgctgttccaggaggcgctgtgtcacgtgcccgagcacgccgtg
gtgctggagatagccccccatgccctgctgcaggccgtcctgaagagaggcctcaaggcc
agctgcgccatcatccccctgatgaagagggaccacagggacaacctggagttcttcctc
aggaacgtgggcaggctgcacctgctgggcatcgatgccaaccccaatggcctgtttcca
cccgtggagttcccggtgccccgggggactcctctcatctcgccccacatcaagtgggac
cacagtcaggtgtgggacgtgcctgccgctggggacttccccagcggctccagcggctcc
tccacagccaccgtctacaacatcgacaccagccccgagtcccctgaccactacctggtg
gaccactgcatcgatggccgcgtcctcttccccgccactggctacctgtgcctggcctgg
aaggtgctggcgcgtgccttgagccagaacatggaagacgtgcctgtggtgtttgaggat
gtgacgctgcaccaggccaccatcttgcccaagtccgggactgtggccctggaagttcgg
ctcctggaggcttcccgcacctttgaggtgtctcagaacggcaacctgatcgtgagcggg
aaggtgtaccagtgggaggaccctgatcccaagctcttcgaccgcggggatggcccggac
cccgcagaccccacggaccccacagccacgttccgcctgtcccagggggatgtgtacaag
gagctgcggctacgtggctatgattatggcccgtacttccagggcattctggagaccaac
cttgaaggcaacacaggccaactgttgtggaaggacaactgggtgaccttcctggacacc
atgctgcagatgtccatcctgggcatcgtccagcgcaccctgcgtctgcccacccgcatc
acctccatccacatcgatcccgccactcaccggcagaaggtgtactcactcaagggccag
gcccaagtggctgacgtggtggtgagcagctgtctgaacagcacagcggccggtggcgtc
ctcatctcgggcctgcacgcctccgtggccccgaggcggcagcaggagcagcttgccccc
agcctggagaagttctgcttcaccccccacgtggagggggggctcctggctggaaacgca
gccttgcaggaggagctgcagctgtgcagggggctggcacaggcactgcagaccaaggtg
gcccagcaggggctgaagatggtggtacctgggctggatggggcccaggtcccccgggag
cccccacagcaaggcctgcctcagctactggcagccgcctgccagctccagctcaacggg
agcctgcagctggagctggaccagctgctggcccagcagaggcccctgctgcacgacgac
cctctgctcagcggcctgctcgattccccggcactcaaggcctgcgtggacaccgccctg
gagaacctgaccagccccaggatgtacattgtagaggtgctggctggtgatggccgcctg
tattcccgcgttccggcgctgctcaacacgcagcccatgctgcagctggactacacggcc
acggaccgccacccgcaggcgctggaggctgcccaggccaagctacaggaatacggcatg
gcccagggccagtgggaccctgcagaccccgcccccagcagcctgggcgcggccgacctg
ctggtgtgcaactgtgccgtggcccccctccgtgacccagccacggccctcggcaacatg
gcggccgctctcaaggagggcggcttcctgctgctgcacgtcctgctccgaggacacccc
ctgggagagacggtggccttcctcacctgcccggagcagcgaggcccgcagagcctcctg
agtcaggatgagtgggagggtctgttcgccgcagcgtccctgcacctggcggccctgaag
cgctccttctacggctcggcgctcttcctgctgcgccggccggccccgcgggacagcccc
gtcttcctgcccgtggaggacaccagcttccgatgggtggactccctgaagaacgtcatg
gccgacaactcgtcccgacccgtgtggctgacggctgtcagctgcgccacctcgggcgtc
gtgggcatggtgaactgtctccgacgggagcctggcgggcaccggattcgatgcatcctg
gtatccaacctcagcagcacgtcccctgtccccaagatggacccgagctcctcagagttg
cagaaagtgttacagggggacctcgtgatgaatgtctaccgggacgggtcctggggggcc
ttccgccatttcccactggagcgtggcctgccagaggagcagaccgagcatgccttcgtc
aacgtcctcacccggggggacctgtcctctatccgctgggtctgctcccctctgcgtcac
gtccagcccactgagcccggcgtctacctctgcaccgtcaactatgcctctctcaacttc
cgagacatcatgctggccacgggcaagctgtcccctgatgccatcccagggaaatgggcc
gcccgggaatgtatgttgggcatggagttctctggccgggacgccagtggcaagcgtgtg
atggggctggtgcccgctgaaggcctggccacctccgtcgtgctgtcccaggatttcctg
tgggatgtgccgtctagctggaccctggaggaggcggcgtccgtgcctgtggtctatact
accgcctactactcgctcgtggtgcggggacgcgtgcggcgcggggagacggtgctcatc
cactcgggctcgggcggcgtgggccaggccgccatcgccatcgccctgagcctgggctgc
cgcgtcttcaccaccgtggggtcagccgaaaagcgggcgtacctccaggccaggttcccc
cagctgagcgatgccagctttgccaactcccgggacacgtcctttgaacaacacgtgctg
cggcacacggccgggaagggtgtcgacctggttctgaactctctggcggaagagaagctg
caggccagcgtgcggtgcctggcccagcacggccgattcctggaaatcggcaaattcgac
ctttccaacaaccaccagctgggcatggccatcttcctgaaaaacgtggccttccacggg
attctgctggactcgctcttcgacgaggccagcagcgagtggcgggaggtggcgggcctg
ctgcaggcgggcatccgggacggcgtggtgcagccgctcaagtgcaccacgttccccaag
caccaggtggaggacgcgttccgctacatggcccaagggaagcacatcggcaaagtggtc
gtgcaggtgctcgaggagcaagaggccgtgccgcaggtgaccaggcccctgctgatgacg
gctgcgtccaagactttctgcccagcccacaagagctatgtcatcactgggggcctgggc
gggttcggccttgagctggcccagtggcttgtgctgcgaggggcccagaaactcgtgctg
acctctcgctctgggatccgcacaggctaccaggccaagcaagtccgtgagtggaggcgc
cagggcgtgcaggtcctggtgtccaccagcaacgccagctcgctagatggggcccagagc
ctcatcgcggaggccacgcagctggggcctgtgggaggtgttttcaacctggccatggtc
ctgagagacgccatgctggagaaccaaacccccgagtttttccaggatgtcagcaagccc
aaggccagtggtaccgtgaacttggacagggtgacccgggcagcatgccccgagctggac
tacttcgtggccttctcctccgtgagctgtgggcgcggcaacgctggccaggccaactac
ggcttcgccaactccacgatggagcgcgtgtgtgagaagcgccggcatgacggcctccca
ggcctcgccgtgcagtggggcgccatcggcgatgtgggtgtcgtcctggagacaatgggc
tccaacgacacggtcattggcgggaccctgcctcagcgaatcacctcctgcttggaggtg
ctggacctcttcctgaaccagccccaccccgtcttgagcagttttgtgctggctgagaag
aaggccactgcccagggcgacggcagcacccaccaggacctcatgaaggcggtggcccac
atcctaggcatccgagacttggccaccgtgaacctggacagcacactggcggacctgggc
ctggactcgctcatgggcgtggaggtgcgccagatgctggagcgtgagcacgacctggtg
ctgtccatgcgggacatccggcagctcacgcttcgcaagttgcaggagctttcctcgaag
gccagcacagctgacgagctgggagcccccacgcccaaggacaacagctccaccagtcag
caggcccagctgaacctgagcaccctgctggtgaaccccgagggcccgaccttgacacgg
ctcaactcggtgcagagctcggagcggccgctgttcctggtgcatcccatcgaaggctcc
gtcaccgtgttccacagcctggccgccaagctcagcatccccacctatggcttgcagtgt
acccgagctgcacccctggacagcatccagagcctggccgcctactacatcgagtgcatc
cggcaggtgcagcctgaggggccctaccgcattgccggctactcgtacggggcctgcgtg
gccttcgagatgtgcttccagctgcagacgcagcagagcccggcccccacacacaacagc
ctcttcctgttcgacggctcgcacacctacgtgctggcctacacgcagagctaccgcgcc
aagatgacccggggctgcgaggccgaagctgaggccgaggctatgtgcttcttcgtgcag
cagttcatagacatggagcacgacagggtgctggaggcgctgctgcccctcgggggcctg
gaggagcgtgtggcggccgccgtggacctgatcaagcgcagccacacaggtctggaccgc
cgagagctgagcttcgccgcgcgctccttctactacaagctgcgcgcggccgaggagtac
gcgccgcaggccacctaccacggcaacgtgacgctgctgcgcgccaagaccagcagcgtg
tacggcgagggcctgggcgccgactacagcctgtcgcaggtgtgcgacggcaaggtgtcc
gtgcacgtgatcgagggggaccaccgcacgctgctggagggcagcggcctggactccatc
gtcagcatcatccacggctccctggccgagccgcgcgtcagcgtgcgggagggctag
DBGET
integrated database retrieval system
