Ursus americanus (American black bear): 123778572
Help
Entry
123778572 CDS
T07931
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04022
cGMP-PKG signaling pathway
uar04024
cAMP signaling pathway
uar04062
Chemokine signaling pathway
uar04071
Sphingolipid signaling pathway
uar04270
Vascular smooth muscle contraction
uar04310
Wnt signaling pathway
uar04360
Axon guidance
uar04510
Focal adhesion
uar04520
Adherens junction
uar04530
Tight junction
uar04611
Platelet activation
uar04670
Leukocyte transendothelial migration
uar04810
Regulation of actin cytoskeleton
uar04921
Oxytocin signaling pathway
uar05132
Salmonella infection
uar05135
Yersinia infection
uar05163
Human cytomegalovirus infection
uar05200
Pathways in cancer
uar05205
Proteoglycans in cancer
uar05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
123778572 (ROCK2)
04071 Sphingolipid signaling pathway
123778572 (ROCK2)
04024 cAMP signaling pathway
123778572 (ROCK2)
04022 cGMP-PKG signaling pathway
123778572 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123778572 (ROCK2)
04520 Adherens junction
123778572 (ROCK2)
04530 Tight junction
123778572 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123778572 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123778572 (ROCK2)
04670 Leukocyte transendothelial migration
123778572 (ROCK2)
04062 Chemokine signaling pathway
123778572 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
123778572 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
123778572 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
123778572 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123778572 (ROCK2)
05205 Proteoglycans in cancer
123778572 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
123778572 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
123778572 (ROCK2)
05135 Yersinia infection
123778572 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123778572 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123778572 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
uar03036
]
123778572 (ROCK2)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
123778572 (ROCK2)
Protein kinases [BR:
uar01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
123778572 (ROCK2)
Chromosome and associated proteins [BR:
uar03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
123778572 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
APH
Irp3-like_C
Motif
Other DBs
NCBI-GeneID:
123778572
NCBI-ProteinID:
XP_045631969
LinkDB
All DBs
Position
Unknown
AA seq
1475 aa
AA seq
DB search
MSRPPATGKMPGAPEAVPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLV
GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWN
WDNIRETAAPVVPELSSDVDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
LLGDSSSCRENDSVQSRKNEESQEIQKKLYTLEEHLSTEIQAKEELEQKCKSVNTRLEKV
AKELEEEITLRKNVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
DLQDKNCLLETAKLKLEKEFINLQSVLESERRDRTHGSEIINDLQGRISGLEEDLKNGKV
LLAKAEMEKRQLQERLADLEKEKNNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKKLSEERTLKQKVENLLLEAEKRCSIFDCDLKQSQQKINELLK
QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMS
LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKAKLCKELQQK
KQDLQEERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDAQEQLSRLKDEEISAAAIKAQF
EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGSDTDMRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
DAEPDDGFPVHITQSRTMESMSFTYQRSSTSLNIATKPSSSHMLLDSDSDSEEEPLPYLP
ISSEPNGTESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLD
IDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGH
EFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDI
STAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQ
LAPNKPRLLDLAFKDWDWSFDDVDGGDDDDDVFDF
NT seq
4428 nt
NT seq
+upstream
nt +downstream
nt
atgagccggcccccggcgacggggaaaatgcccggcgcccccgaggccgtgccgggggac
ggggcgggcgcaagccgccagaggaagctggaggcgctgatccgagaccctcgctcgccc
atcaacgtggagagcttgctggatggcttaaattccttggtccttgatttggattttcct
gctttgaggaaaaacaagaatatagataattttttaaatagatatgagaaaattgtgaaa
aaaatcagaggtctacagatgaaggcagaagactatgatgttgtaaaagttattggaaga
ggtgcttttggtgaagtgcagctggttcgtcataaggcatcacagaaggtttatgctatg
aagcttcttagtaagtttgaaatgataaaaagatctgattctgcttttttctgggaagag
agagatattatggcctttgccaacagtccctgggtggttcagctcttttgtgcttttcaa
gatgataagtatctgtacatggtaatggagtacatgcctggtggagatcttgtaaacctt
atgagtaactatgatgtacctgaaaaatgggccaaattttatactgctgaagttgttctt
gctctggatgccatacactccatgggcttaattcacagagatgtaaagcctgacaacatg
ctcttggataagcatggacatctaaagttggcagattttggcacatgtatgaagatggat
gaaacaggcatggtgcattgtgatacagcagttggaacacccgattatatttcacctgag
gttctcaaatcacaagggggcgatggttactatgggcgagaatgtgattggtggtctgtg
ggtgttttcctttttgaaatgctggtgggggatactccattttatgcagattcacttgta
ggaacatatagcaaaattatggatcataaaaactcactgtgtttccctgaagatgcagaa
atttctaagcatgcgaagaatctcatttgcgccttcttaacagatagggaggtacgactt
gggagaaatggggtagaagaaatcaaacagcatcctttctttaagaatgatcaatggaat
tgggataacataagagagacggcggcccctgtagtacctgaactcagcagtgacgtagac
agcagcaattttgatgacatcgaagatgataaaggagatgtagaaaccttcccgattcct
aaagcttttgtgggaaatcagctgccttttataggatttacctactatagagaaaatttg
ttattaggtgactcttcatcttgtagagaaaacgactcagtacaatcaaggaaaaacgaa
gaaagtcaagagattcagaaaaaattatacacattagaagaacaccttagcactgagata
caagccaaagaggaactagagcagaagtgcaaatctgttaatactcgccttgagaaagta
gcaaaggaactagaagaagagattactttaaggaaaaatgtggaatcagcattaagacaa
ttagaaagagaaaaggcacttcttcagcacaaaaatgcagaatatcagcggaaagctgat
cacgaagcagacaagaaacgaaatttggaaaatgatgttaacagtttaaaggatcaactt
gaagatttgaaaaaaagaaatcagaactctcagatatccactgagaaagtgaatcagctc
cagagacaactggatgaaaccaatgctttgctgagaacagaatctgatactgcagcccgg
ttaagaaaaacccaagcagaaagttcaaaacagattcagcagctggaatctaacaataga
gatcttcaagataaaaattgcctgctggagactgccaagttaaaacttgaaaaggaattt
atcaatcttcagtcagttctagaatctgaaaggagagaccgaacccatggatccgagata
attaatgacttacaaggtagaatatctggcctagaagaagatttaaagaatggcaaagtc
ttattggcaaaagcagagatggagaagagacaactacaggagagacttgccgatttggaa
aaggaaaagaacaacatggaaatagatatgacgtaccaactgaaagttatacagcagagc
ttagaacaagaagaagctgagcataaggctacaaaagcacggctggcagataaaaataag
atttatgaatccattgaagaagcgaaatcagaagccatgaaagaaatggagaaaaagctc
tcagaggaaaggacgttaaagcagaaagtggagaacctattgctggaagctgagaagaga
tgctctatatttgactgtgacctcaaacagtcacagcagaaaataaatgaactccttaag
cagaaagatgtgctaaatgaggatgttagaaatttgacattaaaaatagagcaggaaact
cagaagcgctgccttacacaaaatgacttgaagatgcaaacacagcaagttaacacacta
aaaatgtcagaaaagcagttaaaacaagagaataatcatctcatggaaatgaaaatgagc
ttggaaaagcagaatgctgaacttcgaaaagaacgtcaagatgcagatgggcaaatgaaa
gaacttcaggatcagcttgaagcggagcagtatttctcaaccctctataaaacacaggtg
agggaacttaaagaagaatgtgaagaaaaggccaaactttgtaaagaattacaacagaag
aaacaggacttacaggaggaaagggactccctggctgctcaactggagatcaccttgacc
aaagcagattctgagcagctggctcgttcaattgctgaagagcaatattctgatttggaa
aaagagaaaatcatgaaggagcttgagatcaaagagatgatggctagacacaaacaggaa
ctcactgaaaaagatgctacaattgcatctcttgaagaaacgaacaggacactaactagt
gatgttgccaatcttgcaaatgagaaagaagaattaaataacaaattgaaagatgcccaa
gaacagctgtcacggctgaaagatgaggagatcagcgcagccgctattaaagcacagttt
gagaagcagctgctcacagagagaacactcaaaactcaggctgtgaataagttggctgag
atcatgaatcgaaaagaacctgtcaagcgtggtagtgacaccgatatgcggagaaaagag
aaagagaatagaaagctacatatggagcttaaatctgaacgtgaaaaactgacccagcag
atgatcaagtatcagaaagaactgaatgaaatgcaggctcaaatagctgaagagagccag
attcgaattgaactgcagatgacactggacagtaaagatagtgacattgagcagctgcgg
tcacagctccaggcgttgcatattggtctggatagttccagtataggcagtggaccaggg
gatgctgagcccgatgatggatttccagttcatatcactcaatcacgcactatggaatcc
atgtcattcacctaccaacgttcctctacttctctcaatattgccactaagccttccagt
tctcatatgcttcttgactctgattctgactcagaagaagaacctttgccttacttacct
atttcatcggaacctaatggtacagaatcaagactagaaggatggctttcattgcctgta
cgaaacaacactaagaaatttggatgggttaaaaagtatgtgattgtaagcagtaagaag
attcttttctatgacagtgaacaagataaagaacaatctaatccttacatggttttagat
atagacaaattatttcatgtccgaccagttacacagacagatgtatatagagcggatgct
aaagaaattccaaggatatttcagattctgtatgccaatgaaggagaaagtaagaaggaa
caagaatttccagtggagccagtgggagaaaaatcaaattatatttgccataaaggacat
gaatttattcctactctctatcatttcccaaccaactgtgaggcttgtatgaagccattg
tggcatatgtttaaacctccccctgctttagagtgccggcgctgccatattaaatgtcat
aaagatcacatggacaaaaaggaggagattatagcgccttgcaaagtttattacgatatt
tcgacggcaaagaatctattgttgttagcaaattctacagaagagcagcagaagtgggtt
agtcggttagtgaaaaagatacctaaaaagcctccagctccagacccttttgcacggtca
tctcctagaacttcgatgaagatacagcaaaaccagtctattagacggccaagtcgacag
cttgccccaaacaaaccaagattgcttgatttggcatttaaagactgggattggtcattt
gatgatgttgatggtggtgatgatgatgacgatgtttttgatttctga
DBGET
integrated database retrieval system
