Ursus americanus (American black bear): 123778834
Help
Entry
123778834 CDS
T07931
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04014
Ras signaling pathway
uar04072
Phospholipase D signaling pathway
uar04148
Efferocytosis
uar04360
Axon guidance
uar04625
C-type lectin receptor signaling pathway
uar04630
JAK-STAT signaling pathway
uar04650
Natural killer cell mediated cytotoxicity
uar04660
T cell receptor signaling pathway
uar04670
Leukocyte transendothelial migration
uar04722
Neurotrophin signaling pathway
uar04920
Adipocytokine signaling pathway
uar04931
Insulin resistance
uar05168
Herpes simplex virus 1 infection
uar05205
Proteoglycans in cancer
uar05208
Chemical carcinogenesis - reactive oxygen species
uar05211
Renal cell carcinoma
uar05220
Chronic myeloid leukemia
uar05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
123778834 (PTPN11)
04630 JAK-STAT signaling pathway
123778834 (PTPN11)
04072 Phospholipase D signaling pathway
123778834 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123778834 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
123778834 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
123778834 (PTPN11)
04660 T cell receptor signaling pathway
123778834 (PTPN11)
04670 Leukocyte transendothelial migration
123778834 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
123778834 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
123778834 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
123778834 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
123778834 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
123778834 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123778834 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
123778834 (PTPN11)
05211 Renal cell carcinoma
123778834 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
123778834 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
123778834 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
uar01009
]
123778834 (PTPN11)
Enzymes [BR:
uar01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
123778834 (PTPN11)
Protein phosphatases and associated proteins [BR:
uar01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
123778834 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
123778834
NCBI-ProteinID:
XP_045632427
LinkDB
All DBs
Position
Unknown
AA seq
597 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDSKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLTDQTSGDQSPLPPCTPTPSCAEMREDNARVYENVGLMQQQKSFR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaacatcactggcgtggaggcagaaaacctgctg
ctgacaagaggagttgatggcagttttttggcaaggcccagtaaaagtaaccctggagac
ttcaccctttccgtcagaagaaatggcgctgtcacccacatcaagattcagaacactggt
gattactatgacttgtacggaggggagaagtttgccactttggctgagttggtccagtat
tacatggaacatcacgggcaattaaaagagaagaatggagatgttattgagcttaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattactaactgagaaaggaaaacatggtagctttctggtacgagagagc
cagagccatcccggagattttgttctctctgtccgaactggtgatgacaaaggggagagc
aatgacagcaagtctaaagtgacccacgtcatgatccgctgtcaggaactgaaatatgat
gttggtggaggagaacggtttgactctttgacagaccttgtggagcattacaagaagaat
cccatggtggagacattgggcacagtactacaactcaagcagcccctcaacacaacacgt
atcaatgctgctgaaatagaaagtcgggttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgaaaagagggtcagaggcaagaaaataagaacaaaaatagatataaa
aacatcctgccctttgatcataccagggttgtcctacacgatggtgatcccaatgagcct
gtttcagattacatcaatgcaaatattatcatgcctgagtttgaaaccaaatgcaacaat
tcaaagcccaaaaagagttacattgccacacaaggctgtctgcaaaacacggtgaatgac
ttttggcggatggtatttcaagagaactcccgagtgattgtcatgacaacgaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgacgagtatgctctgaaagaatat
ggggtcatgcgtgttaggaacgtcaaagaaagtgccgctcatgactatacattaagagaa
cttaaactttcaaaggttggacaagctctactccaggggaatacagagagaaccgtgtgg
cagtaccactttcggacctggccggaccacggagtgcccagtgaccctgggggcgtgctg
gacttcctggaggaggtccaccataagcaagagagcattatggacgcagggcccgtggta
gttcactgcagtgctggaatcggccggacagggacgttcattgtgattgatatccttatt
gacatcatcagagagaaaggcgtcgactgcgacatcgatgttcccaaaaccattcagatg
gtgcggtctcagaggtcagggatggtccagacagaagcacagtaccgattcatctatatg
gccgtccagcattacattgaaacactacagcgcaggattgaagaagagcagaaaagcaag
aggaaagggcatgaatatacaaatattaagtattctctaacggaccagacaagtggagat
cagagtcccctcccgccttgtaccccaacaccatcttgtgcagaaatgagagaagataat
gctagagtctatgaaaacgtgggtctgatgcagcagcagaaaagtttcagatga
DBGET
integrated database retrieval system
