KEGG   Ursus americanus (American black bear): 123781846
Entry
123781846         CDS       T07931                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X1
  KO
K13375  transforming growth factor beta-1
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04010  MAPK signaling pathway
uar04060  Cytokine-cytokine receptor interaction
uar04068  FoxO signaling pathway
uar04110  Cell cycle
uar04148  Efferocytosis
uar04218  Cellular senescence
uar04350  TGF-beta signaling pathway
uar04380  Osteoclast differentiation
uar04390  Hippo signaling pathway
uar04659  Th17 cell differentiation
uar04672  Intestinal immune network for IgA production
uar04926  Relaxin signaling pathway
uar04932  Non-alcoholic fatty liver disease
uar04933  AGE-RAGE signaling pathway in diabetic complications
uar05140  Leishmaniasis
uar05142  Chagas disease
uar05144  Malaria
uar05145  Toxoplasmosis
uar05146  Amoebiasis
uar05152  Tuberculosis
uar05161  Hepatitis B
uar05166  Human T-cell leukemia virus 1 infection
uar05200  Pathways in cancer
uar05205  Proteoglycans in cancer
uar05210  Colorectal cancer
uar05211  Renal cell carcinoma
uar05212  Pancreatic cancer
uar05220  Chronic myeloid leukemia
uar05225  Hepatocellular carcinoma
uar05226  Gastric cancer
uar05321  Inflammatory bowel disease
uar05323  Rheumatoid arthritis
uar05410  Hypertrophic cardiomyopathy
uar05414  Dilated cardiomyopathy
uar05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123781846 (TGFB1)
   04350 TGF-beta signaling pathway
    123781846 (TGFB1)
   04390 Hippo signaling pathway
    123781846 (TGFB1)
   04068 FoxO signaling pathway
    123781846 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    123781846 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    123781846 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    123781846 (TGFB1)
   04218 Cellular senescence
    123781846 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    123781846 (TGFB1)
   04672 Intestinal immune network for IgA production
    123781846 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    123781846 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123781846 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123781846 (TGFB1)
   05205 Proteoglycans in cancer
    123781846 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123781846 (TGFB1)
   05212 Pancreatic cancer
    123781846 (TGFB1)
   05225 Hepatocellular carcinoma
    123781846 (TGFB1)
   05226 Gastric cancer
    123781846 (TGFB1)
   05220 Chronic myeloid leukemia
    123781846 (TGFB1)
   05211 Renal cell carcinoma
    123781846 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123781846 (TGFB1)
   05161 Hepatitis B
    123781846 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    123781846 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    123781846 (TGFB1)
   05144 Malaria
    123781846 (TGFB1)
   05145 Toxoplasmosis
    123781846 (TGFB1)
   05140 Leishmaniasis
    123781846 (TGFB1)
   05142 Chagas disease
    123781846 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    123781846 (TGFB1)
   05321 Inflammatory bowel disease
    123781846 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    123781846 (TGFB1)
   05414 Dilated cardiomyopathy
    123781846 (TGFB1)
   05415 Diabetic cardiomyopathy
    123781846 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    123781846 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123781846 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:uar03110]
    123781846 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:uar04052]
    123781846 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:uar00536]
    123781846 (TGFB1)
Chaperones and folding catalysts [BR:uar03110]
 Intramolecular chaperones
  Others
   123781846 (TGFB1)
Cytokines and neuropeptides [BR:uar04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   123781846 (TGFB1)
Glycosaminoglycan binding proteins [BR:uar00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   123781846 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 123781846
NCBI-ProteinID: XP_045637582
LinkDB
Position
Unknown
AA seq 391 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVENTNKI
YEKIKKSPHSIYMLFNTSELREAVPEPVLLSRAELRLLRLKLKAEQHVELYQKYSNDSWR
YLSNRLLAPSDTPEWLSFDVTGVVRQWLSHGGEVEGFRLSAHCSCDSKDNTLQVDINAGF
SSSRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLY
IDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQ
ALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgccgccctccgggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgacgcctggccggccggccgccggactgtccacctgcaagaccatcgacatggaactg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc
agccccccgagccagggggaggtgccgcccggcccgctgcccgaggctgtgctggccctt
tacaacagtacccgcgaccgggtggcgggggagagcgccgagccggagcccgagcctgag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaacaccaacaaaatc
tatgagaaaatcaagaaaagcccacacagcatctatatgctcttcaacacatcggagctc
cgagaagcagtgcccgagcccgtcttgctctcccgggcggagctgcgcctgctgaggctc
aagttgaaagccgagcagcacgtggagctgtaccagaaatatagcaacgattcctggcgc
tacctcagcaaccggctgctggcgcccagcgacacgccagaatggctgtccttcgatgtc
acaggagtcgtgcgacagtggctgagccatggaggggaagtagagggctttcgcctcagt
gcccactgttcctgtgacagcaaagataatacactgcaagtggatatcaacgcagggttc
agttccagccgccgaggtgacctggccaccattcacggcatgaaccggcccttcctgctc
ctcatggccaccccactggagagggcccagcacctgcacagctcccggcatcgccgggcc
ctggacaccaactactgcttcagctccaccgaaaagaactgctgcgtacggcagctctac
atagacttccgcaaggatctgggctggaagtggatccacgagcccaagggctaccacgcc
aacttctgcctggggccctgcccctacatttggagcctggacacgcagtacagcaaggtc
ctggcgctgtacaaccagcacaacccgggcgcgtcggcggcgccgtgctgcgtgccgcag
gcgctggagcccctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctg
tccaacatgatcgtgcgctcctgcaagtgcagctga

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