KEGG   Ursus americanus (American black bear): 123782571
Entry
123782571         CDS       T07931                                 
Symbol
CXCR4
Name
(RefSeq) C-X-C chemokine receptor type 4
  KO
K04189  C-X-C chemokine receptor type 4
Organism
uar  Ursus americanus (American black bear)
Pathway
uar03250  Viral life cycle - HIV-1
uar03260  Virion - Human immunodeficiency virus
uar04020  Calcium signaling pathway
uar04060  Cytokine-cytokine receptor interaction
uar04061  Viral protein interaction with cytokine and cytokine receptor
uar04062  Chemokine signaling pathway
uar04144  Endocytosis
uar04360  Axon guidance
uar04670  Leukocyte transendothelial migration
uar04672  Intestinal immune network for IgA production
uar04810  Regulation of actin cytoskeleton
uar05163  Human cytomegalovirus infection
uar05170  Human immunodeficiency virus 1 infection
uar05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:uar00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    123782571 (CXCR4)
   03260 Virion - Human immunodeficiency virus
    123782571 (CXCR4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    123782571 (CXCR4)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    123782571 (CXCR4)
   04061 Viral protein interaction with cytokine and cytokine receptor
    123782571 (CXCR4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    123782571 (CXCR4)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123782571 (CXCR4)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    123782571 (CXCR4)
   04672 Intestinal immune network for IgA production
    123782571 (CXCR4)
   04062 Chemokine signaling pathway
    123782571 (CXCR4)
  09158 Development and regeneration
   04360 Axon guidance
    123782571 (CXCR4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123782571 (CXCR4)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123782571 (CXCR4)
   05163 Human cytomegalovirus infection
    123782571 (CXCR4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:uar04030]
    123782571 (CXCR4)
   04050 Cytokine receptors [BR:uar04050]
    123782571 (CXCR4)
   04090 CD molecules [BR:uar04090]
    123782571 (CXCR4)
G protein-coupled receptors [BR:uar04030]
 Rhodopsin family
  Chemokine
   CXC Chemokine
    123782571 (CXCR4)
Cytokine receptors [BR:uar04050]
 Chemokine receptors
  CXC Chemokine
   123782571 (CXCR4)
CD molecules [BR:uar04090]
 Proteins
  123782571 (CXCR4)
SSDB
Motif
Pfam: 7tm_1 CXCR4_N 7TM_GPCR_Srsx DUF4538
Other DBs
NCBI-GeneID: 123782571
NCBI-ProteinID: XP_045638776
UniProt: A0A452SH46
LinkDB
Position
Unknown
AA seq 353 aa
MDAFRIYPSDNYTEDDLGSGDYDSMKEPCFREENAHFNRIFLPTVYSIIFLTGIVGNGLV
ILVMGYQKKLRSMTDKYRLHLSVADLLFVLTLPFWAVDAVANWYFGKFLCKAVHVIYTVN
LYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVRE
ADGRYICDRFYPNDSWLVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGYQKRKALK
TTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFESTVHKWISITEALAFFHCCLNP
ILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
NT seq 1062 nt   +upstreamnt  +downstreamnt
atggacgcgttccgtatatacccttcagataactacacagaagatgacttgggctcaggc
gactatgactccatgaaggaaccctgcttccgggaggaaaatgcccatttcaaccgtatc
tttctgcccacggtctactccatcatcttcttgacgggcatagtgggcaatggattggtc
atcctggtcatgggttaccagaagaaactgagaagcatgacagacaagtatagactacac
ctgtctgtggcagacctcctctttgtcctcacgcttcccttctgggcagttgatgctgtg
gccaactggtactttggaaagttcctgtgcaaggcagtccatgtcatctatacagtcaac
ctctatagcagtgtccttatcctggccttcatcagtctggaccggtacttggctattgtc
catgccaccaacagtcagaggccaaggaagctgttggctgaaaaggtggtctatgttggc
gtctggatacctgctctcctgttgaccattcctgatttcatctttgccaatgtcagggag
gcagatgggaggtatatctgtgaccgcttctatcccaatgactcgtggttggtggtgttc
cagtttcagcacatcatggttggccttatcctgccaggcattgtcatcctgtcctgctac
tgcattatcatctccaagctgtcccactctaagggctaccagaagcgcaaggccctcaag
accacagttatcctcatcctggctttcttcgcctgctggctgccctactacattgggatc
agcatcgattccttcatcctcctggaaatcatcaagcaaggatgtgagtttgagagcact
gtgcacaagtggatttccatcactgaggccctggcctttttccactgttgcctgaacccc
atcctctatgccttcctcggagccaaatttaaaacctctgcccaacatgcactcacctct
gtgagcagagggtccagcctcaagatcctttccaaagggaagcggggaggacattcttct
gtttcaaccgaatccgagtcttcaagttttcattccagctaa

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