KEGG   Ursus americanus (American black bear): 123786085
Entry
123786085         CDS       T07931                                 
Symbol
HTRA2
Name
(RefSeq) serine protease HTRA2, mitochondrial
  KO
K08669  HtrA serine peptidase 2 [EC:3.4.21.108]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04210  Apoptosis
uar04215  Apoptosis - multiple species
uar05012  Parkinson disease
uar05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:uar00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    123786085 (HTRA2)
   04215 Apoptosis - multiple species
    123786085 (HTRA2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    123786085 (HTRA2)
   05022 Pathways of neurodegeneration - multiple diseases
    123786085 (HTRA2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:uar01002]
    123786085 (HTRA2)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:uar03110]
    123786085 (HTRA2)
Enzymes [BR:uar01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.108  HtrA2 peptidase
     123786085 (HTRA2)
Peptidases and inhibitors [BR:uar01002]
 Serine peptidases
  Family S1: chymotrypsin family
   123786085 (HTRA2)
Chaperones and folding catalysts [BR:uar03110]
 Other chaperones and cochaperones
  DegP / HtrA
   123786085 (HTRA2)
SSDB
Motif
Pfam: Trypsin_2 Trypsin PDZ_6 PDZ_2 PDZ Peptidase_S46 GRASP55_65 PDZ_Tricorn
Other DBs
NCBI-GeneID: 123786085
NCBI-ProteinID: XP_045644322
UniProt: A0A452S7B3
LinkDB
Position
Unknown
AA seq 458 aa
MAALRAGRGAVWNLRGWRAVGGVRWGKGPLLTPDLRALLTSGTPDPRAGVTYGTPSLRAR
LSVGVPEPRTCLQSGTSDSRPRLTAGTPDPRTREVSGTPGTRPRVWLAVALGAGGAVLLL
LWGGGRGPPAVLASVLGSPPTSPRSQYNFIADVVEKTAPAVVYIEILGRHPFSGREVPIS
NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAMVTAVDPVADIATLRIQTKEPL
PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA
IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRR
YIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILDSPAHRAGLRPGDVILAIGEQL
VQNAEDIYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE
NT seq 1377 nt   +upstreamnt  +downstreamnt
atggctgcactgagggcggggcggggtgcagtctggaacctccggggatggcgggctgtc
gggggcgttcgctgggggaagggacccctgttgacccctgacctccgggccttgctgacg
tcaggaactcctgaccctcgggccggagtgacttatgggacccccagtctccgggcccgg
ttgtctgtgggggtccctgaaccacggacgtgtctgcaatcggggacttcggattcccga
ccacggctgactgcagggaccccagatcccaggacccgggaggtctcagggacccctgga
acccgtccgcgcgtatggctggcggtggcgctgggcgctgggggggcagtgctgttgtta
ttgtggggcgggggtcggggtcccccagcggtcctcgcctcggtccttggctcgccgccc
acctctccccggagccagtacaacttcatcgcagacgtggtggagaagacagcacctgct
gtggtttatatcgagatcttgggccggcaccctttctcgggccgcgaagtccctatctcg
aatggctcaggattcgtggtggctgccgacgggctcatcgtaaccaacgctcatgtggtg
gctgatcggcgccgggtccgtgtgaggctgcttagcggtgacacgtatgaggccatggtc
acagctgtggatcccgtggcagacattgccacgctgaggattcagactaaggagcctctc
cccacactacccttgggacgctcagctgatgtccggcaaggggagtttgttgttgccatg
ggaagtccctttgcactgcagaatacgatcacttctggcattgtcagctctgctcagcgt
ccagccagagacctgggcctcccccaaaccaatgtggaatacatccagactgatgcagct
attgattttggaaattctggaggtcctctggttaacctggatggggaggtgattggagtg
aataccatgaaggtcacagctggaatctcctttgccatcccttctgatcgccttcgagag
tttctgcatcgtggggaaaagaagaattcctggtttggaatcagtgggtcccagcgccgc
tacattggggtgatgatgctgaccctgactcccagcatccttgctgaactacagcttcga
gaaccaagttttcctgatgttcagcatggtgtgctcatccataaagtcatcctggactcc
cctgcacaccgggctggtctacggccgggtgatgtgatcttggccattggggagcagctg
gtacaaaacgctgaagatatttatgaagctgttcgaacccaatcccagctggcagtgcgc
atccggcggggaccggaaacattgaccttatatgtgacccctgaagtcacagaatga

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