Ursus americanus (American black bear): 123786093 Help Entry 123786093         CDS       T07931                                  Symbol HK2 Name (RefSeq) hexokinase-2   KO K00844   hexokinase [EC:2.7.1.1] Organism uar  Ursus americanus (American black bear) Pathway uar00010   Glycolysis / Gluconeogenesis uar00051   Fructose and mannose metabolism uar00052   Galactose metabolism uar00500   Starch and sucrose metabolism uar00520   Amino sugar and nucleotide sugar metabolism uar00524   Neomycin, kanamycin and gentamicin biosynthesis uar01100   Metabolic pathways uar01200   Carbon metabolism uar01250   Biosynthesis of nucleotide sugars uar04066   HIF-1 signaling pathway uar04910   Insulin signaling pathway uar04930   Type II diabetes mellitus uar04973   Carbohydrate digestion and absorption uar05230   Central carbon metabolism in cancer Module uar_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate uar_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     123786093 (HK2)    00051 Fructose and mannose metabolism     123786093 (HK2)    00052 Galactose metabolism     123786093 (HK2)    00500 Starch and sucrose metabolism     123786093 (HK2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     123786093 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     123786093 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     123786093 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     123786093 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     123786093 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     123786093 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     123786093 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uar04131]     123786093 (HK2) Enzymes [BR:uar01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      123786093 (HK2) Membrane trafficking [BR:uar04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     123786093 (HK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  123786093 NCBI-ProteinID:  XP_045644332 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDENLLEISKRFRKEMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDLMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCVQTKLDESFLVSWTKGFKSSGV EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGTLDDFRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKVSPGLLTTGQFETKDVSDIEGEKDGTRKAREVLVRLG MDPTQEDCVATHRICQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH PHFAKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQNTLESLKLS REQLLEVKRRMNVEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD FRTEFDVAVDELSLNPGRQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILRHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgcctcgcatctgctcgcctacttcttcacggagctcaaccatgaccaagtgcag aaggtcgaccagtatctctaccacatgcgtctttctgatgagaaccttctggagatctct aagcggttccgcaaggagatggagaaagggcttggagccaccacccaccccactgcttca gtgaaaatgctgcccacctttgtgaggtctactccagatggaacagaacacggagagttt ctggctctggacctcggagggacaaacttccgtgtacttcgggtaagagtaacggacaat gggctccagaaggtggagatggagaaccagatctatgccatccctgaggacctcatgcgg ggcagcggcacccagctgtttgaccacattgcggaatgcctggctaacttcatggataag ctacaaatcaaagacaagaagctccccttgggttttactttctcattcccctgcgtccaa acgaaactagatgagagtttcctggtctcctggaccaaggggttcaagtccagtggtgtg gaaggcaaagacgtggttactctgatccgaaaggccatccagaggagaggggactttgat attgatattgtggccgtggtgaatgacacagttgggaccatgatgacctgtggttatgat gaccagaattgcgagattggtctcattgtaggcacgggcagcaatgcctgctacatggaa gagatgcgccacattgacatggtggagggagacgaggggcggatgtgtatcaacatggag tggggggccttcggggacgacggcacgctcgatgacttccgcaccgagtttgatcaggag atcgacatgggctccctgaaccccgggaagcaactatttgagaagatgatcagtgggatg tacatgggagaactggtgaggcttatcctggtgaagatggccaaggaagagctgctcttt ggggggaaggtcagcccagggctccttaccactggccagtttgagaccaaagacgtttca gacattgaaggggagaaggacggcacccggaaggcgcgtgaggtgctggtgcggctgggc atggacccgacacaggaggactgcgtggccactcaccggatctgccagatcgtgtctacg cgctcagccagcctgtgcgcggccaccctggcggccgtgctgcggcgcatcaaggagaac aagggcgaggagcggctgcgctccaccattggggtggatggctctgtctacaagaagcac ccacactttgccaagcgtcttcacaaggccgtccggcgcctggtgcccgactgcgacgtc cgcttcctgcgttccgaggatggcagcggcaagggggcggccatggtgacggcggtggcc taccggctggccgaccaacaccgggcccgccagaacaccctggagtctctgaagctgagc cgcgagcagctgctggaggtcaagaggaggatgaacgtggaaatggagcgaggtctgagc aaggagactcacgccattgcccccgtcaagatgctgcccacctacgtgtgcgccacgcct gacggcacagagaagggtgacttcctggccttggaccttgggggtaccaacttccgggtc ctgctggtgcgcgtgaggaacggaaagcggcgtggagtggagatgcacaacaagatctac tctatcccgcaggaggtcatgcacggcacaggggatgagctctttgaccacatcgtccag tgcatcgctgacttccttgagtacatgggcatgaagggcgtgtccctgcccctgggtttc accttctccttcccctgccagcagaacagcctggatgagagcatcctcctcaagtggacc aaaggcttcaaggcatcgggctgcgagggagaggacgtggtcacgctgctgaaggaggcc atccaccggcgagaggagtttgacctggacgtggttgccgtggtgaatgacacggtcggg actatgatgacctgtggctatgaagaccctcactgtgaagttggcctcatcgttggcaca ggcagcaacgcctgctacatggaggagatgcggaacgtggagctggtggagggggaagag ggccggatgtgtgtcaacatggagtggggggccttcggggacaacggatgcctcgatgac ttccgcacggaatttgatgtggctgtggatgagctttccctcaaccctggcagacagagg ttcgagaaaatgatcagtggcatgtacttgggtgagattgtccgtaacatcctcatcgat ttcaccaagcgtgggctgctcttccgtggccgcatctcagagcggctcaagacaagagga atctttgaaaccaagttcctgtctcagattgagagtgactgcctggccctgctgcaggtg cgcgccatcctgcgccacctggggctcgagagcacctgtgacgacagcatcattgtcaaa gaggtgtgcaccgtggtggcgcggcgggcggcccagctctgtggtgcgggcatggccgcc gtggtggacaagatacgagaaaaccgggggctggacaccctcaaagtgaccgtgggcgtg gatgggaccctctacaagctacatccccactttgccaaagtcatgcacgagacggtgaag gacttggctccgaaatgtgacgtgtccttcctggagtcagaggacggcagcgggaagggg gcggctctcatcactgctgtggcctgccgcatccgcgaggctggccagcgatag

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