Ursus americanus (American black bear): 123786709
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Entry
123786709 CDS
T07931
Symbol
UGT2A1
Name
(RefSeq) UDP-glucuronosyltransferase 2A1 isoform X1
KO
K00699
glucuronosyltransferase [EC:
2.4.1.17
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00040
Pentose and glucuronate interconversions
uar00053
Ascorbate and aldarate metabolism
uar00140
Steroid hormone biosynthesis
uar00830
Retinol metabolism
uar00860
Porphyrin metabolism
uar00980
Metabolism of xenobiotics by cytochrome P450
uar00982
Drug metabolism - cytochrome P450
uar00983
Drug metabolism - other enzymes
uar01100
Metabolic pathways
uar01240
Biosynthesis of cofactors
uar04976
Bile secretion
uar05204
Chemical carcinogenesis - DNA adducts
uar05207
Chemical carcinogenesis - receptor activation
Module
uar_M00014
Glucuronate pathway (uronate pathway)
uar_M00129
Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00040 Pentose and glucuronate interconversions
123786709 (UGT2A1)
00053 Ascorbate and aldarate metabolism
123786709 (UGT2A1)
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
123786709 (UGT2A1)
09108 Metabolism of cofactors and vitamins
00830 Retinol metabolism
123786709 (UGT2A1)
00860 Porphyrin metabolism
123786709 (UGT2A1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
123786709 (UGT2A1)
00982 Drug metabolism - cytochrome P450
123786709 (UGT2A1)
00983 Drug metabolism - other enzymes
123786709 (UGT2A1)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
123786709 (UGT2A1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
123786709 (UGT2A1)
05207 Chemical carcinogenesis - receptor activation
123786709 (UGT2A1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
uar01003
]
123786709 (UGT2A1)
Enzymes [BR:
uar01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.17 glucuronosyltransferase
123786709 (UGT2A1)
Glycosyltransferases [BR:
uar01003
]
Others
Hydrophobic molecule
123786709 (UGT2A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
UDPGT
EryCIII-like_C
Glyco_tran_28_C
Pro_3_hydrox_C
DUF772
Motif
Other DBs
NCBI-GeneID:
123786709
NCBI-ProteinID:
XP_045645005
LinkDB
All DBs
Position
Unknown
AA seq
694 aa
AA seq
DB search
MLNKNVLLWSLTISLLGITLGGNVLIWPMEGSHWLNIKIIIDELIKKEHNVTVLVASGAL
FITPTSNSSLMFEIYKVPFGKERIEGIIKNFVLTWMENRPSPSTIWRFYQEIAKVIKDFH
MLSREICDGVLKNPKLMDKLKKSKFEVLISDPVFPCGDIVALKLGIPFMYSLRFSPASTV
EKHCGKVPFPPSYVPAILSELTDQMSFTDRVRNFMSYHLQDYMFDTLWKSWDSYYSEALD
GSHWLNIKVILEELIQRNHNVTVLASSTTLFINSNPDSPVNFEVIPVSYTNSNIDSFIEH
MIMLWIDHRPTLLTLWTFYKELGKLLDTFFRINVQICDGVLNNPKLMARLQKGGFDVLVA
DPVTICGDLVALKLGIPFVYTLRFSPASTVERHCGKIPAPASYVPAALSEFTDQMTFGER
VKNTISYPLQDYIFQSYWGEWNSYYSKVLGRPTTLCEIMGKAEIWLIRTYWDFEFPRPYL
PNFEFVGGLHCKPAKPLPKVLWRYKGKKPATLGANTQLYDWIPQNDLLGHPKTKAFITHG
GTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNINTMTSEDLLTALRTVINE
PSYKENATRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHNLTWFQYHSLDVIG
FLLACVATAIFLVTKCCLFSCRKFGKTGKKKKRE
NT seq
2085 nt
NT seq
+upstream
nt +downstream
nt
atgttaaacaagaacgttctgctgtggtctcttacgatcagtctcttaggaatcactctc
ggtggtaatgttctgatttggccaatggaagggagtcattggctgaacattaagataatt
atagatgagctgattaaaaaagagcataatgtgactgtcttagttgcctctggtgcactt
ttcatcacgccgacctctaactcgtctctgatgtttgaaatatataaggtgccctttggc
aaagaaagaatagaaggaattatcaagaactttgttttgacatggatggaaaataggcca
tctccttcaaccatttggagattctatcaggagatagccaaagtcatcaaggactttcat
atgctgtctagagaaatctgtgatggtgttctcaaaaacccaaaactaatggacaagctg
aagaaaagcaaatttgaggtcctgatatcagatccagtgtttccttgtggggacatagta
gctttaaaactgggaattccatttatgtactccttgaggttttctccagcttcaacagtg
gaaaagcactgtgggaaggtaccattccctccttcctatgttcctgctatattatcagaa
ctcaccgaccagatgtctttcactgacagagtaagaaatttcatgtcctaccatctgcag
gactacatgtttgacactctttggaaatcatgggattcctactatagtgaagctttggat
ggtagccattggttaaatattaaggtcattctagaagagctgattcaaagaaatcacaat
gtgactgtactggcttcatcaacaactctattcatcaactctaaccctgattctcctgtg
aattttgaggtgatacctgtctcctacacgaacagcaatatagactccttcattgaacac
atgataatgctgtggatagaccacagaccaactcttctcacactctggactttctataaa
gaactaggaaaacttctagatactttttttcgaatcaatgtacaaatctgtgatggagta
ttaaacaaccccaagttaatggcaagacttcagaaaggtggttttgatgtgttagtagca
gacccagtaactatctgtggggacctggttgctctgaaattaggaattccatttgtgtac
acattgaggttctctccagcctccacagttgagagacattgtgggaaaatcccagcacct
gcctcctatgtacctgcggctttgtcagagttcactgaccagatgacatttggtgagagg
gttaaaaatactatctcttatcctctgcaagactacatatttcagtcctactggggagaa
tggaattcatactacagcaaagttctaggaagacccactacattgtgtgagattatggga
aaagcagaaatttggctaatccggacgtattgggattttgaatttcctcgtccatactta
cctaattttgagtttgtaggaggcttgcattgtaaacctgccaaaccattacctaaggtt
ttatggagatacaaaggaaagaaaccagctacattaggagccaatactcagctctatgat
tggataccccagaatgatcttcttggtcatcccaaaacaaaagcttttatcactcatggt
ggaaccaatggaatctatgaagctatttatcatggggttcctatggtgggagttcctatg
tttgctgaccaacctgataacatcgctcacatgaaggccaaaggggcggctgtggaggtg
aacataaacacaatgaccagtgaagatctgctcactgccttgagaacagtcattaatgaa
ccttcttataaagagaatgctacaaggttatcgaggattcaccatgaccagcctgtaaag
cccctggatcgggcagtcttctggattgagtttgtcatgcgccacaaaggagccaagcat
ctgcggccagctgctcacaacctcacctggttccagtaccactctctggatgtgattggg
ttcctgctggcctgtgtggcaactgctatattcttggtcacaaaatgttgtttgttttct
tgtcgaaaatttggtaaaacaggaaagaagaaaaagagggaatag
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