Ursus americanus (American black bear): 123787201 Help Entry 123787201         CDS       T07931                                  Symbol CDK4 Name (RefSeq) cyclin-dependent kinase 4   KO K02089   cyclin-dependent kinase 4 [EC:2.7.11.22] Organism uar  Ursus americanus (American black bear) Pathway uar01522   Endocrine resistance uar04110   Cell cycle uar04115   p53 signaling pathway uar04151   PI3K-Akt signaling pathway uar04218   Cellular senescence uar04530   Tight junction uar04660   T cell receptor signaling pathway uar04933   AGE-RAGE signaling pathway in diabetic complications uar04934   Cushing syndrome uar05160   Hepatitis C uar05162   Measles uar05163   Human cytomegalovirus infection uar05164   Influenza A uar05165   Human papillomavirus infection uar05166   Human T-cell leukemia virus 1 infection uar05167   Kaposi sarcoma-associated herpesvirus infection uar05169   Epstein-Barr virus infection uar05200   Pathways in cancer uar05203   Viral carcinogenesis uar05212   Pancreatic cancer uar05214   Glioma uar05218   Melanoma uar05219   Bladder cancer uar05220   Chronic myeloid leukemia uar05222   Small cell lung cancer uar05223   Non-small cell lung cancer uar05224   Breast cancer uar05225   Hepatocellular carcinoma Brite KEGG Orthology (KO) [BR:uar00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     123787201 (CDK4)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     123787201 (CDK4)    04115 p53 signaling pathway     123787201 (CDK4)    04218 Cellular senescence     123787201 (CDK4)   09144 Cellular community - eukaryotes    04530 Tight junction     123787201 (CDK4)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     123787201 (CDK4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123787201 (CDK4)    05203 Viral carcinogenesis     123787201 (CDK4)   09162 Cancer: specific types    05212 Pancreatic cancer     123787201 (CDK4)    05225 Hepatocellular carcinoma     123787201 (CDK4)    05214 Glioma     123787201 (CDK4)    05220 Chronic myeloid leukemia     123787201 (CDK4)    05218 Melanoma     123787201 (CDK4)    05219 Bladder cancer     123787201 (CDK4)    05224 Breast cancer     123787201 (CDK4)    05222 Small cell lung cancer     123787201 (CDK4)    05223 Non-small cell lung cancer     123787201 (CDK4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     123787201 (CDK4)    05160 Hepatitis C     123787201 (CDK4)    05164 Influenza A     123787201 (CDK4)    05162 Measles     123787201 (CDK4)    05163 Human cytomegalovirus infection     123787201 (CDK4)    05167 Kaposi sarcoma-associated herpesvirus infection     123787201 (CDK4)    05169 Epstein-Barr virus infection     123787201 (CDK4)    05165 Human papillomavirus infection     123787201 (CDK4)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     123787201 (CDK4)    04934 Cushing syndrome     123787201 (CDK4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     123787201 (CDK4)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:uar01001]     123787201 (CDK4) Enzymes [BR:uar01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.22  cyclin-dependent kinase      123787201 (CDK4) Protein kinases [BR:uar01001]  Serine/threonine kinases: CMGC group   CDK family    123787201 (CDK4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like Motif Other DBs NCBI-GeneID:  123787201 NCBI-ProteinID:  XP_045645680 LinkDB All DBs Position Unknown AA seq 303 aa AA seqDB search MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLQKAEG NPE NT seq 912 nt NT seq  +upstreamnt  +downstreamnt atggctactcctcgatatgagccagtggctgagattggtgttggtgcctatggaacggta tacaaggcccgtgatcctcacagcggccacttcgtggccctcaagagcgtaagagtccct aatggaggaggtgctggagggggccttcccatcagcacagttcgtgaggtggccttactg cggcggctggaggcttttgagcatcccaacgtcgtccggctgatggatgtctgtgccacc gcccgcactgaccgggagaccaaagtgactctggtgtttgagcacgtggaccaagacctg aggacatatctggacaaggcacccccaccaggcttgccagtggagaccatcaaggatctg atgcgccagtttctaagaggcctagatttccttcatgccaactgcatcgttcaccgagac ctgaagccagagaacattctcgtgaccagtggtgggacagtcaagctagctgactttggc ctggccagaatctacagctaccagatggcacttacacctgtggttgttacactctggtac cgtgccccagaagttcttctgcagtctacatacgcaacacccgtggacatgtggagtgtt ggctgtatcttcgcagagatgtttcgtcgaaagcccctcttctgtggaaactctgaagct gaccagttaggcaaaatctttgacctgatcgggctgcccccagaggatgactggccccga gatgtgtctctgcctcgaggagccttttcccccagagggccccgcccagtgcagtcagtg gtacctgagttggaggagtctggagcacaactgctgctggagatgctgacttttaaccca cacaagcgaatctctgccttccgagccctgcagcactcttatctacaaaaggcagaaggt aacccagagtga

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