Ursus americanus (American black bear): 123787262
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Entry
123787262 CDS
T07931
Symbol
ERBB3
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar01521
EGFR tyrosine kinase inhibitor resistance
uar04010
MAPK signaling pathway
uar04012
ErbB signaling pathway
uar04020
Calcium signaling pathway
uar04151
PI3K-Akt signaling pathway
uar05205
Proteoglycans in cancer
uar05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123787262 (ERBB3)
04012 ErbB signaling pathway
123787262 (ERBB3)
04020 Calcium signaling pathway
123787262 (ERBB3)
04151 PI3K-Akt signaling pathway
123787262 (ERBB3)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
123787262 (ERBB3)
05205 Proteoglycans in cancer
123787262 (ERBB3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123787262 (ERBB3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123787262 (ERBB3)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123787262 (ERBB3)
Protein kinases [BR:
uar01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
123787262 (ERBB3)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
Kinase-like
TM_ErbB1
DUF4381
Motif
Other DBs
NCBI-GeneID:
123787262
NCBI-ProteinID:
XP_045645858
LinkDB
All DBs
Position
Unknown
AA seq
1340 aa
AA seq
DB search
MRAKAALQVLGFLLNLAGGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAVFVM
LNYHTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG
RSCPPCHEACKGRCWGPRPEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD
TDCFACRLFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTS
CVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNITSLGLRSLREISAGRIYISANRQLCYHHSLNWTRLLRGPAEE
RLDIKHNRPRRDCVAEGKVCDRLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEP
REFAHEAECFSCHPECRPMEGAATCNGSGSDACAQCAHFRDGPHCVNSCPSGVLGAKGPI
YKYPDAQNECRPCHENCTQGCKGPELQDCLGQTLALISKTHLAVGLTVVVGLAVIFLILG
GTFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVF
GTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQDVTDHMLAIGSLDHAHIVRLLGLCPG
SSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVT
VWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRDSGPGISPGAEPPALTNKELEEVELEPELELDLDLEAEED
GLATTLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLGETCQESAVCGSGERCPRP
ASLHPVPRGRLASESSEGHVMTGSEAELQEKVSMCRSRSRSPRPRGDSAYHSQRHSLLTP
VTPLSPPGLEEEDVNGYVMPDAHLKGTPSSREGTLSSVGLSSVLGTEEEDEDDEYEYMNR
RRRRSPTRPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLNPGPLMPAAGTTPDEDYEY
MNRRHGGGAPGGDYAAMGACPAAEQGYEEMRAFQGPGHHTPHVHCARLKTLRSLEATDSA
FDNPDYWHSRLFPKANAQRT
NT seq
4023 nt
NT seq
+upstream
nt +downstream
nt
atgagggcgaaggcggctctgcaggtgctgggcttccttctcaacctggccgggggctcc
gaggtgggcaactcccaggcagtgtgtcctgggactctgaatgggctgagcgtgacgggt
gatgccgagaaccagtaccagaccttgtataagctctacgagaggtgcgaggtggtgatg
gggaacctcgagattgtgctcacaggacacaacgccgacctctccttcctgcagtggatc
cgagaagtgactggctatgtcctcgtggccatgaatgagttctctacgctgccactgccc
aacctccgggtggtgcggggcactcaggtgtacgatgggaagtttgccgtctttgtcatg
ctgaactatcacaccaactccagccacgctctgcgccagctccgttttactcagctcact
gagattctgtcggggggcgtttatattgagaagaatgataaactttgtcacatggacaca
atcgactggagggacatcgtgagggaccgagatgccgagatagtggtgaaggacaatggc
aggagctgtcccccgtgtcatgaggcctgcaaggggcggtgctggggtcctagaccagaa
gactgccagacattgaccaagaccatctgtgctcctcagtgtaacggtcactgctttggg
cccaaccccaaccagtgctgccatgatgagtgcgcaggaggctgctcgggcccccaggat
acagactgctttgcctgtcgactcttcaatgacagcggggcctgtgtgcgccagtgtcca
cagcctcttgtttacaacaagctcacgttccagctggaacccaatccccataccaagtat
cagtatggtggagtttgtgtagccagctgtccccataacttcgtggtggatcagacatct
tgtgtccgggcctgtcctcctgacaagatggaagtagataaaaatggactcaagatgtgt
gaaccttgtggggggctgtgccccaaagcctgtgaggggacaggctcggggagccgcttc
cagactgtggactccagcaacatcgatggatttgtgaactgcaccaagatcctggggaac
ctggactttcttatcactggcctcaatggagacccctggcacaagatccctgccctggac
cccgagaagctcaacgtcttccggacagtacgagagatcacaggttacctaaacatccag
tcctggcctccccacatgcacaacttcagtgtcttttccaacctgacaaccatcgggggc
agaagcctatacaaccggggcttctctttgttgatcatgaagaacttgaatataacctct
ttgggcctccgatctctgagagaaattagtgccgggcgtatctacataagcgccaacagg
cagctctgctaccaccattctctgaactggaccaggctgctgcgggggcctgcggaagag
agactagacatcaagcacaatcggccccgcagggactgcgtggcagagggcaaagtgtgt
gatcgcctgtgctcctctgggggatgctggggcccaggtcctggtcagtgcctgtcctgt
cgaaactacagccgaggaggtgtctgtgtgacccactgcaactttctgaatggggagcct
cgtgagtttgcccatgaggctgaatgcttctcctgccacccggagtgccgacccatggag
ggtgctgccacgtgcaacggctcgggctctgatgcttgtgctcagtgtgcccattttcga
gatggtccccactgtgtgaacagctgccccagtggagtcctcggtgccaagggccccatc
tacaagtacccagatgctcagaatgaatgtcggccctgccacgagaattgcacccagggg
tgtaagggaccagagctacaagactgtttaggtcaaacactggcactgatcagcaaaacc
catctggcagtgggtttaacagtggtagtagggttggcagtgattttcctgatcctggga
ggcacttttctctattggcgtgggcgccggattcagaataagagggctatgaggcggtac
ttggaacggggtgagagcatagagcctctggatcccagtgagaaggctaacaaagtcttg
gccagaatcttcaaagaaacagagctgaggaagcttaaagtgcttggttcaggcgtcttt
ggaaccgtgcacaaaggagtatggattcctgagggtgaatcaatcaagattccagtctgc
attaaagtcattgaggacaagagtggacggcaaagtttccaagatgtgacggatcatatg
ctggctattggcagcctagaccatgcccacattgtacggctgctgggactgtgccctggg
tcatctctgcagctcgtcactcagtacttgcctctgggctccctgctggatcacgtgaga
caacaccgtggagcactggggccccagctgctgctcaactggggagtacagattgccaag
ggaatgtactaccttgaggagcatggtatggtgcacaggaacctggcggcccgaaatgtg
ctactgaagtcacccagtcaggttcaggtggcagattttggggtggctgacctgcttccc
cccgatgataagcaactactacacagtgaggccaagactccaattaagtggatggccctg
gagagtatccactttgggaaatacacacaccagagtgacgtctggagttatggagtgacc
gtttgggagctgatgacctttggggcggagccctatgctggactacgactggctgaagta
ccagacctgctagagaagggggagcgattggcgcagccccagatctgtaccattgatgtc
tacatggtcatggtcaagtgttggatgattgatgagaacattcgtccaacctttaaagaa
ctagccaatgagttcaccaggatggcccgagacccaccacggtatctggtcataaagaga
gacagtgggcctggaatctcccctggggcagagccccctgctctgacaaacaaggaactg
gaggaggtggagctggagccagaactagagctagacctggacttggaggcagaagaggac
ggtctggcgactacactaggctctgccctcagcctgccagttggaacacttaatcggccc
cgtgggagccagagccttttaagcccatcatctggatatatgcctatgaaccagggtaat
cttggggagacttgccaggagtctgcagtttgtgggagtggtgagcggtgccctcgtcca
gcctctttgcacccagtgccacggggacgcctggcatcagagtcctcagagggccatgtg
atgacgggctctgaggctgagctccaggagaaggtgtcaatgtgtaggagccggagccgg
agcccacggccacgtggagacagtgcctaccattcccagcgccacagcctgctcactcct
gtcaccccactgtccccaccagggttagaggaagaggatgtcaatggatatgtcatgcca
gatgcacacctcaaaggtactccctcctcccgggaaggcaccctttcttcagtgggcctc
agttctgtcctgggtactgaagaagaagatgaagatgatgagtacgaatacatgaaccgg
aggagaaggcgcagtccaactcgtccccctaggcccagttctctcgaggagctgggttat
gagtacatggatgtgggatcagacctcagtgcttccctgggcagcacacagagttgccca
ctcaaccctgggcccctcatgcccgctgctggcacaaccccagatgaggactatgaatat
atgaatcggcgacatggcggaggagcccctgggggagattacgcagccatgggcgcctgc
ccagcagctgagcaggggtatgaagagatgagagctttccaggggcctggacaccataca
ccccatgtccattgtgcccgcctcaaaactctccgtagtttagaagccactgactctgct
tttgacaaccctgattactggcatagcaggcttttccccaaggctaatgctcagagaaca
taa
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integrated database retrieval system
