Ursus americanus (American black bear): 123788968 Help Entry 123788968         CDS       T07931                                  Symbol FLNC Name (RefSeq) filamin-C isoform X1   KO K27393   filamin-C Organism uar  Ursus americanus (American black bear) Pathway uar04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:uar00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     123788968 (FLNC)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:uar04812]     123788968 (FLNC) Cytoskeleton proteins [BR:uar04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Cross-linking proteins      123788968 (FLNC)   Intermediate filaments    Intermediate filament-binding proteins     123788968 (FLNC) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Filamin Ig_GEX2_N CH Big_3_5 Invasin_D3 CFSR CH_2 Motif Other DBs NCBI-GeneID:  123788968 NCBI-ProteinID:  XP_045648631 LinkDB All DBs Position Unknown AA seq 2718 aa AA seqDB search MMNNSGYSEAALGLGDEVDDMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPHGNTVLQPAHFTV QTVDAGLGEVLVYIEDPEGHTEEAKVVPNNDKNRTYAVSYVPKVAGLHKVTVLFAGQNIE RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR RDTVEVALEDKGDSTFRCTYRPVMEGPHTVHVAFAGAPITRSPFPVHVAEACNPNACRAS GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV VPGKYVVTITWGGYAIPRSPFEVQVSPEAGAQKVRAWGPGLKTGQVGKSADFVVEAIGTE VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHIQP AAPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLNLYAQDADGCPVNITVIP NGDGTFRCSYVPTKPIKHTIIVSWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA KLDVHFAGAAKGEAVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV APPLDLSKVKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG AETQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI PGSPFKATIRPVFDPSKVRASGPGLERGKAGEAATFTVDCSEAGEAELTIEILSDAGVKA EVLIHNNADGTYHITYKPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGIKVSGPGV EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPSRVRAFGPGLEGGLVNKANHFTVETRGAGT GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTAGDYDVNITFGGRPIPGSPFRVPVKDV VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLHVAVLGPTGVAEPVEVLDNGGGT HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGEETVITVDAKAAGKGKVTC TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPMAH GEEPSDMPQLRRPSTYPTHWATEEPVVPAEPMESMLRPFNLVIPFTVQKGELTGEVRMPS GKTARPNITDNKDGTITVRYAPTEKGLHHMGIKYDGNHIPGSPLQFYVDAINSRHVSAYG PGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDY SIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSLLTASIRAPSG NEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRV WGKGLSEGQTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPG TYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKIPGNWFQ MVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPAVFGDFL GRERLGSFGSITRQEGEASSQDMTAQVTSPSGKMEAAEIVEGEDSAYSVRFVPQEMGPHT VTVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGL SIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDD ARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELDSDKHTIR FIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFI VNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVITYTPMAPGNYLIAIKYGGPQHIVGSP FKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQ AFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILI VKWGDESVPGSPFKVNVP NT seq 8157 nt NT seq  +upstreamnt  +downstreamnt atgatgaacaacagcggctactcggaggccgcgctcggcctgggcgacgaggtggacgac atgccgtccacggagaaggacctcgcggaggacgcgccgtggaagaagatccagcagaac acattcacgcgctggtgcaacgagcacctcaagtgcgtgggcaagcgcctgaccgacctg cagcgcgacctcagcgacgggctgcgcctcatcgcgctgctcgaggtgctcagccagaag cgcatgtaccgcaagttccacccgcgccccaacttccgccagatgaagctggagaacgtg tccgtggccctcgagttcctcgagcgcgagcacatcaagctcgtgtccatcgacagcaag gccatcgtggacgggaacctgaagctgatcctggggctcatctggacgctgatcctgcac tactccatttccatgcccatgtgggaagacgaggacgacgaggacgcccgcaagcagacc cccaaacagcgtctgcttggctggatccagaacaaggtgccgcagctgcccatcaccaac ttcaaccgcgactggcaggacggcaaggctctgggcgccctggtggacaactgcgcccct ggcctctgccccgactgggaggcctgggaccccaaccagcctgtggagaacgcccgggag gccatgcagcaggcggacgactggctcggggtgccccaggtgattgcccccgaggagatc gtggaccccaacgtggatgagcattctgtcatgacctacctgtcccagttccccaaggcc aaactcaaacctggtgcccctgttcgctccaagcagctgaaccctaagaaggccatcgcc tacgggcccggcatcgagccccatggcaacaccgtcctgcagcccgcccacttcaccgtg cagacggtggacgccggcctgggcgaggtgctggtctacatcgaggaccccgagggccac actgaggaggccaaggtggttcccaacaacgacaagaaccgcacctacgcggtctcctac gtgcctaaggtcgctgggctgcacaaggtgaccgtgctctttgctggccagaacatcgaa cgcagtcccttcgaggtgaacgtgggcatggccctgggggatgccaacaaggtgtcagcc cgcggccctggcctggagcccgtgggcaatgtggccaacaaacccacctacttcgacatc tacacggcgggggccgggactggtgatgttgccgtggtgatcgtggacccgcagggccgg cgggacacagtggaggtggccctggaggacaagggcgacagcacgttccgatgcacatac aggcctgtgatggaggggccccacacggtgcacgtggccttcgctggtgcccccatcacc cgcagtcctttccccgtccatgtggccgaagcctgtaaccccaacgcctgccgcgcctct ggacggggcctgcagcccaagggtgtgcgcgtgaaagaggtggctgacttcaaggtgttc actaagggtgccggcagtggggagctcaaggtcacagtcaaggggccaaagggcacagag gagccggtgaaggtgcgggaggctggggacggtgtgttcgagtgtgagtactaccctgtg gtacctgggaagtacgtggtgaccatcacatggggcggctacgccatcccccgcagcccc tttgaggtacaggtgagcccagaggcaggagcacagaaggtacgggcctggggtcccggc ctcaaaacgggccaggtgggcaagtcagccgactttgtggtggaggccatcggcacggag gtggggacactgggcttctccattgaggggccctcgcaggccaagatcgagtgtgatgac aagggggatggctcctgcgacgtgaggtactggcccacagagcccggggagtacgccgtg catgtcatctgtgacgatgaggacatccgagactcgcccttcattgcccacatccagccg gccgcacctgactgcttcccagacaaggtgaaggccttcgggcccggcctggagcccact ggctgcatcgtggacaagcctgctgagttcaccatcgatgcccgcgctgccggcaagggc gacctgaatctgtatgcccaggatgctgatggctgccccgtcaacatcacggtcatcccc aatggcgacggcaccttccgctgctcctacgtgcccaccaagcccattaaacacaccatc atcgtctcctggggcggtgtcaacgtgcccaagagccccttccgggtaaatgtgggagaa ggcagtcaccccgagcgggtgaaggtgtacggcccaggcgtggagaagacgggcctcaag gccaacgagcccacctacttcacagtggactgcagcgaggccggccaaggtgacgtgagt attggcatcaagtgcgcccctggcgtcgtgggccctgcagaagctgacatcgactttgac atcatcaagaatgacaatgacaccttcacagtcaagtacacacccccaggagccggccgc tacaccattatggtgctgtttgccaaccaggagatccctgccagccccttccatattaag gtggacccatcccacgatgccagcaaggtcaaggctgagggcccagggctgaaccgtaca ggtgtggaagttgggaagcccactcacttcacggtgctgaccaagggagccggcaaggcc aagctggacgtgcactttgcgggggccgccaagggcgaggctgtgcgggactttgaaatc atcgacaaccacgactactcctacactgtcaagtacacagccgtccagcagggtaacatg gcagtgacagtgacctatggtggggaccctgtccctaagagcccctttgtggtgaacgtg gcgcccccattggacctgagcaaagtcaaagttcaaggcctgaacagcaaggtggccgtg gggcaagaacaggcattctccgtgaacacgcgtggggctggcggtcagggccagctggac gtgcggatgacctcgccctcccgccgacccatcccctgcaagctggagcccgggggtggg gccgaaacccaggctgtgcgctacatgccccccgaggagggaccctacaaggtggacatc acctacgacggccacccagtgccgggcagcccctttgccgtggagggtgtcctgcctcct gacccctccaaggtctgtgcttacggccctggtctcaagggcggactggtgggcacccca gcccccttctccattgacaccaagggggctggcacaggcggcctggggctgaccgtggag ggcccctgcgaggccaagatcgagtgccaggacaatggtgatggttcctgtgccgtcagc tacctgcccaccgagccgggcgagtacaccatcaacatcctgtttgccgaagcgcacatc cctggctcacccttcaaggccaccatccggcccgtgttcgacccgagcaaggtgcgggcc agcgggccgggcctggagcgtggcaaggccggcgaggcggccaccttcaccgtggactgc tcggaggcgggcgaggccgagctgaccatcgagatcctgtcggacgccggcgtcaaggcc gaggtcctgatccacaacaatgccgacggcacctaccacatcacctacaaacccgccttt cctggcacctacaccattaccatcaagtatggcgggcaccccgtccccaaattccccacc cgcgtccatgtgcagcctgccgtcgacaccagtggaatcaaggtctcggggcctggggtg gagcctcatggtgtcctgcgggaggtgaccaccgagttcactgtggatgcgagatcccta acggccacaggtgggaaccacgtgacagcgcgtgtgctcaacccctcgggtgcgaagacg gacacctacgtgacggataacggggatggcacctaccgagtgcagtacacagcctacgag gagggcgtgcatctggtggaggtgctgtacgatgaggtagctgtgcccaagagccccttc cgagtgggcgtgacggagggctgtgaccccagccgcgtgcgggcctttgggccaggcctg gagggcggcttggtcaacaaggccaaccacttcaccgtggagaccaggggagctggcact ggaggcctaggcctagccattgagggcccctcggaagccaagatgtcctgcaaggacaac aaagatggcagctgtaccgtggagtacatccccttcacagccggggactacgatgtcaac atcacctttggggggcggcccatcccagggagcccgttccgggtgcctgtgaaggatgtg gtggaccctgggaaggtgaagtgctcagggccagggctgggggccggtgtcagggcccgg gtgccccagaccttcacagtggactgcagccaagccggccgggccccgctgcacgtggcc gtgctgggccccacaggtgtggctgagcccgtggaggtgctggacaatggaggtggcacc cacactgtccactacaccccggccaccgatgggccctacacggtagctgtcaagtacgcc gaccaggaggtgccgcgcagccccttcaagatcaaggtgcttcctgcccacgatgccagc aaggtgcgggccagtggccccggcctcaacgcctctggcatccccgccagcctgcccgtg gaattcaccattgatgcccgggatgctggtgagggtttgctcaccgtccagatcctggac cctgagggaaagcccaagaaggccaacatccgagacaacggggatggcacatacaccgtg tcctacctgccagacatgagtggccggtacaccatcaccatcaagtatggtggcgacgag atcccctactcgcccttccgcatccacgccctgcccacgggggatgccagcaagtgtctt gtcacagtgtccattggaggccatggcctgggtgcctgcctgggaccccgcatccagatc ggggaggagaccgtgatcacggtggatgccaaggcagcaggcaagggcaaggtgacatgc acagtgtccacgccggatggggcagagctcgacgtggacgtggttgagaaccacgacggt acctttgacatctactacacggcgcccgagccgggcaagtacgtcatcaccatccgcttt ggaggcgagcacatccccaacagccccttccacgtgctggcgtgtgaccccatggcccac ggggaggagccgtctgacatgccgcagctgcgtcggcccagcacctaccctacgcactgg gccacagaggagccagtggtacccgcagagcccatggagtccatgctgaggcccttcaac ctggtcatccccttcaccgtgcagaaaggggaactcacaggggaggttcggatgccctcc gggaagacggcccggcccaacatcaccgacaacaaggacggcaccatcacggtgaggtac gcgcccactgagaaaggcctgcaccacatggggatcaagtacgacggcaaccacatcccc ggaagccccctgcagttctacgtggacgccatcaatagccgccacgtcagtgcctatggg ccaggcctgagccacggcatggtcaacaagccggccaccttcaccattgtcaccaaggac gctggggaagggggtctgtccctggccgtggagggcccatccaaggccgagatcacctgc aaggataacaaggatggcacctgcactgtgtcctacctgcccacggcgcccggagactac agcatcatcgtgcgctttgatgacaagcacatcccggggagccccttcacagccaagatc acaggtgatgactccatgcgcacatcacagctgaatgtgggcacctccacggacgtgtca ctgaagatcaccgagagtgacctgagcctgctgaccgccagcatccgggcgccctcgggc aacgaggagccctgcctgttaaagcgcctgccgaaccgccacattggcatctccttcacc cccaaggaagttggggagcacgtggtaagcgtgcgcaagagtggcaagcacgtcaccaac agccccttcaagatcctggtggggccgtcggagatcggggacgccagcaaggtgcgcgtc tggggcaagggcctgtccgagggacaaaccttccaggtggcggagttcatcgtggacact cgcaatgcaggttatgggggcctgggactgagtatcgaaggccctagcaaagtagacatc aactgtgaggacatggaggacggcacgtgcaaagtcacctactgccccactgagcccggc acctacatcatcaacatcaaatttgctgacaagcacgtgcccggaagccccttcaccgtg aaggtgacgggcgaaggccgcatgaaggaaagcatcacccggcgcagacaggcgccttcc atcgccaccatcggcagcacctgtgacctcaacctcaagatcccagggaactggttccag atggtgtccgcccaggagcgcctgacgcggaccttcacccgcagcagccacacgtacacc cgcacggagcgcacggagatcagcaagacgcggggcggggagaccaagcgcgaggtgcgg gtggaggagtccacccaggtcggtggagacccctttcccgccgtcttcggggacttcctg ggccgggagcggctgggctccttcggcagcatcacgcggcaggagggtgaggccagttct caggacatgaccgcacaggtgaccagcccatcgggcaagatggaagccgcagagattgtc gagggagaagacagtgcgtacagcgtgcgtttcgtgccccaggagatggggccccacacg gtcactgtcaagtaccgcggccagcatgtacctggcagcccctttcagttcactgtgggg ccacttggagaaggtggagcccacaaagtgagggctggaggcacaggactcgagagaggg gtggccggcgtgccagctgagttcagcatttggacccgagaagcaggtgccgggggcctg tccattgctgtggagggtcccagcaaggcggagattgcatttgaggaccgaaaagatggc tcctgtggggtctcctatgttgtccaggaaccaggtgattatgaggtctccatcaagttc aatgacgagcacataccagacagcccctttgtggttcctgtggcctctctctccgatgac gctcgccgcctcaccgtcaccagcctccaggagacggggctcaaggtgaaccagccggcg tcctttgcagtgcagctgaatggtgctcggggcgtgatcgatgcacgtgtgcacacgccc tcgggcgccgtggaggagtgctacgtctccgagctggacagcgacaagcacaccatccgc ttcatcccccacgagaatggcgtccactctattgatgtcaagttcaacggtgcccacatc cctggcagtcccttcaagatccgcgttggggagcagagccaggctggggacccaggcttg gtgtcagcttatggtcctgggcttgaggggggcactactggcgtgtcatcagagttcatt gtcaacaccctgaacgcgggctcaggggccttgtctgtcaccatcgatggcccctccaag gtgcagctggactgtcgggagtgtcctgagggccatgtgatcacttacactcccatggcc cccggcaactacctcattgctatcaagtacggtggcccccagcacatcgtgggcagcccc ttcaaggccaaagtcacaggtccccggctgtctggaggccacagccttcacgaaacctcc acggttctggtggagaccgtgaccaagtcgtcctccagccgcggctccagctacagctcc atcccgaagttctcctcagatgccagcaaggtggtgacacggggcccagggctgtcccag gcctttgtgggccagaagaactccttcactgtggactgcagcaaagcaggcaccaacatg atgatggtgggcgtgcacgggcccaagaccccctgtgaggaggtctacgtgaagcacatg gggaaccgggtatacaacgtcacctacaccgtcaaggagaaaggggactacatcctcatc gtcaagtggggcgacgaaagtgtccccggaagccccttcaaagtcaacgtgccctga

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