Ursus americanus (American black bear): 123790971 Help Entry 123790971         CDS       T07931                                  Symbol C4A Name (RefSeq) complement C4-A   KO K03989   complement component 4 Organism uar  Ursus americanus (American black bear) Pathway uar04610   Complement and coagulation cascades uar04936   Alcoholic liver disease uar05133   Pertussis uar05150   Staphylococcus aureus infection uar05171   Coronavirus disease - COVID-19 uar05322   Systemic lupus erythematosus Brite KEGG Orthology (KO) [BR:uar00001]  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     123790971 (C4A)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     123790971 (C4A)   09171 Infectious disease: bacterial    05133 Pertussis     123790971 (C4A)    05150 Staphylococcus aureus infection     123790971 (C4A)   09163 Immune disease    05322 Systemic lupus erythematosus     123790971 (C4A)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     123790971 (C4A)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uar01002]     123790971 (C4A)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:uar04147]     123790971 (C4A) Peptidases and inhibitors [BR:uar01002]  Peptidase inhibitors   Family I39: alpha2M family    123790971 (C4A) Exosome [BR:uar04147]  Exosomal proteins   Exosomal proteins of hepatic cells    123790971 (C4A)   Exosomal proteins of other cancer cells    123790971 (C4A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TED_complement C4_MG1 A2M A2M_recep A2M_BRD MG2 NTR MG3 ANATO MG4 Big_1 SQHop_cyclase_C Prenyltrans Motif Other DBs NCBI-GeneID:  123790971 NCBI-ProteinID:  XP_045651556 LinkDB All DBs Position Unknown AA seq 1742 aa AA seqDB search MRLLWGLIWVSSFFALSLQKPRLLLFSPSVVHLGVPLSVGVQLEDVPQGQVVTGSVFLRN PSNLNAFCSPKADFSLSSQKDFILLSLQISPKDAETCGLYRLLRGPEVQLVAQSPWLKNS LSRKTDIQGLNLLFSSRRGHLFLQTDQPIYNPGQRVRYRIFALDQKMRPSTDTLTVTVEN SRGLRVRKREVYTSSIFQDDFLIPDIAEPGTWRISARFSDARDSNSSTQFEVKKYVLPNF EVKIVPGKPYILTVPGFLDEIQLDVQARYVYGKPVQGVAYVRFGLLGENGDKTFLRGLES QTKLVDGQCHISLSKAEVQGALEKVHVSVADLPGLRLYVAAAIIESPGGEMEEAELTSWR FVSSPFSLDLSNTKRHLVPGAPFLLQALVRDISGFPASGVPVKVSATLSSGSTSRIQDID QNTDGSGQVVVPIVTPKSISEVQLLVSAGSPHPAIARLTVRAPPSGGSRFLSIERPDPRP PRVGDTLILNLRAVGVSEGSFSHYYYMILSRGQIVSVTREPRTDLTSVSVFVDHHLVPSF YLVAFYYHGGVPVANSLRVDVQPGACEGKLELNVDSAKEYRPGEFVKLHLQTAAPAVVAL GAVDSALYAVGGSSHRPLNMGKVLEVVSSYDLGCGPGGGDNALQVFEAAGLAFSDGDLLT SARKSLSCPKKKTRKKRNVNFQKAIHEKLGQYASPEARRCCQDGLTRLPMIRSCEQRAAR VQQPACRGPFLSCCQFAEDLRKKSRSRGQVGLARALEALQEEDLIDEDDIPVRSFFPENW LWRVENVDRFLQLSQMLPDSLTTWEIHGVSLSKSTGLCVATPARIRVFREFHLHLRLPIS VRRFEQLELRPVLYNYLNKNLTVSVHVSPVEGLCLAGGGGLAQSVLVPAGSARPVAFSVV PTAAAAVSLKVVARGSSDFPVGDAVSKVLQIQKEGAIHTEEIVYELNPLDHRARTLEIPG NSDPNIIPDGDFSSSVRVTASDPLDTLGSKGVLSPGGLASLLRLPQGCGEQTMILLAPTL AASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKTNGSYGAWLERDSSTWLTAFV LKVLSLAQEQVGGSPEKLQETARWLLSQQQADGSFQDPCPVLHRAMQGGLVGDDETVALT AFVVIALQHGLAVFQDDIAEQLKQKVEISIIRANSFLGEKASAGTLGAHAAAITAYALTL TKASEDLRNVAHRNLMAMAQKTGDNLYWGSVPGSQSNAVPATLAPQGPSDPVPQAPAVWI ETTAYGLLHLLLREGKSEEADHAAAWLTHQGSFQGGFRSTQDTVIALDALSAYWIASHTP EERVLNVTLSSVGRSGFKSHELHLNNHQIQGLEEELQFSLGSKINVKVGGNSKGTLKILR TYNVLDLKNTTCEDLQIEVTVTGHVEYTREANEDYEDYVYEELPAKDDPGASSQTVTPLE LFERRRNRRRREAPREPDEQESRVQYTVCIWRNSQVGLSGMAIADITLLSGFSALRADLE KLASLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFGAVQEVAVGLVQPASAALYDYYNP ERTCSVFYAAPTKSKLLSTLCSADVCQCAEGKCPRQRRALERGLQDEEGYRMKFACYYPR VQYGFQVKVLREDGRAAFRLFETRITQVLHFTKDTKATVHQTRNFLVRASCRLRLEPGKE YLIMGLDGATFDLKGDPQYLLDSNTWVEEMPSERLCQSTRHRAACAQLSDFLQEYGAQGC QV NT seq 5229 nt NT seq  +upstreamnt  +downstreamnt atgaggctcctctgggggctgatctgggtgtccagcttcttcgccttatccctgcagaag cccaggttgctcctgttttcaccttccgtggttcacctgggggtccccctctcagtgggg gtgcagctcgaggatgttccccagggacaggtagtgacaggatcagtgttcctgagaaac ccatccaacttgaatgccttctgctccccaaaggcggacttttccctcagctcacaaaaa gacttcatactccttagcctccagatctccccgaaagatgcagagacctgtggcctctac cgcctcctccgtggccccgaggtccagctggtggcccagtcaccatggctgaagaactct ctgtccagaaagacagacattcagggcctcaacctgctcttctcctctcgccgggggcac ctctttctgcagaccgaccagcccatttataaccctggccagcgggttcggtaccggatc tttgctctggatcaaaagatgcgcccatccactgacacccttacggtcacggtagagaac tctcgtggcctccgtgtgaggaagagggaagtgtacacttcctccatcttccaggatgac ttcctgattcctgatatcgcagagccagggacttggaggatctcagcccggttctcagat gcccgagactctaacagcagcacccagtttgaggtgaagaaatatgtccttcccaacttt gaggtgaagattgttcctggaaagccctacatcctgacagtgcctggctttctcgatgag atccaattagacgtccaggccaggtatgtctatgggaagccagtgcaaggggtggcatac gtgcgcttcgggctcctgggtgagaatggcgataagactttccttcgggggctggagagt cagactaagctggtagatggccagtgccatatttccctctcaaaggctgaggttcagggt gccctggagaaggttcatgttagcgttgctgacctccccgggctgcgcctctatgttgca gctgccatcattgagtctccagggggagagatggaggaagcagagctcacatcttggcgt tttgtgtcatctcccttctccttggatcttagcaacaccaagcgacaccttgtgcctggg gccccctttctgctgcaggccctggtccgagacatatctggcttcccggcctctggtgtt cctgtaaaagtttcggctacattgtcttctggatctacttctagaatccaggacatcgac caaaacacagatgggagtggccaagtcgtcgttcccatcgttacaccgaagtccatctca gaagtgcagctcttggtgtctgcaggctcccctcacccagccatagccaggctcactgtg agagccccaccctcaggaggctccaggtttctgtccattgagcggccggatcctcgaccc cctcgcgtcggggacactctcatcctgaacctgcgagctgtgggagtcagtgagggcagc ttctctcattactactacatgatcctatcccggggccagatcgtgtctgtgactcgagag cccaggacggacctgacctcagtctccgtgtttgtggaccatcacttggtaccctccttc taccttgtggccttctactatcatgggggcgtcccagtggccaactccctgcgagtggac gtccagccaggggcctgtgagggcaagctggagctgaacgtggacagtgccaaggagtac cgtcctggggagtttgtaaagctccacctgcagacagccgctccagccgtggtggcgctg ggagccgtggactcggctctgtatgctgtgggtgggagttcgcacaggcccctcaacatg ggcaaggtcttggaagttgtgagcagctatgaccttggctgtggtcctggaggtggggac aatgcccttcaggtgtttgaggcagctggtctggccttttctgatggagacctgttgacc tcagccagaaaaagtctgagctgtcccaagaagaaaacccggaagaagagaaacgtgaac ttccaaaaggcaattcacgagaagttgggccagtatgcttccccagaagccaggcgctgc tgccaggatgggctgacgaggctgcccatgatacgctcctgcgagcagcgggcggctcgg gtgcagcagccggcctgccgggggcccttcctatcctgctgccagtttgctgaggacctg cgcaagaagtcccgctccaggggccaggtgggccttgcccgagctctggaggccctgcag gaggaggacctgatcgacgaagatgacattcctgtgcgcagcttcttcccggagaactgg ctctggagagtggagaacgtggaccgcttcctccaattgtcccagatgctccctgactct ctgaccacatgggagatccatggtgtgagcttgtctaaaagcacaggcctgtgtgtggcc acgcctgcccggatccgagtgttccgtgaattccacctgcacctccgtttgcccatctcc gtccgccgctttgagcagcttgagctgcggccggtcctctacaactacctgaataaaaat ctgactgtgagcgtccacgtgtccccagtggaggggctgtgcctggctggaggtggaggg ctggcccagagtgtcctggtgcctgcaggctctgcccggcctgttgccttctctgtggtg cccacggcggcggcggctgtgtccctgaaggtggtggctcgagggtcctcggacttccct gtgggggacgcagtgtctaaggttctacaaattcagaaagaaggggccatccacacagag gagattgtctatgagctcaatcccctggaccaccgagctcggaccttggagattcctggg aactctgaccccaatatcatcccagatggagatttcagcagctctgtcagggttacagcc tcagatccattggacactttgggctctaagggggtcttgtcaccaggaggcctggcctcc ctgctgaggcttccccagggctgcggggaacaaaccatgatcttactggctccaacactg gctgcttcccgctacctggacaagacggaacagtggagcacgctgccccccgagacgaag gaccacgctgtggacctgatccagaaaggctacatgcggatccagcagtttcggaaaaca aatggttcctacggggcttggttagagcgggacagcagcacctggctcacggcctttgtg ctgaaggtactgagtctggcccaggagcaggtgggcggctcacctgaaaagctgcaggag acggccaggtggctgctgtcccagcagcaggcggacggttcattccaggacccctgcccg gttttacacagggccatgcaggggggcctggtgggagatgatgagactgtggcgctcacg gcctttgtggtcatcgcccttcagcatgggctggccgtcttccaggatgacattgcagag cagttgaagcagaaagtggaaatctccatcatcagagcaaactccttcttgggggagaaa gcgagtgctgggaccctgggtgcccatgcagctgccatcacggcctatgccctgactctc accaaggcttctgaggacctgcggaacgttgcccaccgcaacctcatggccatggcccag aagaccggggataacctgtactggggctcagtccctggttctcagagcaatgctgtccca gccaccctggctcctcaaggcccatcagacccggtgccccaggccccggctgtgtggatt gaaaccacagcctatggcctgcttcacctgctgcttcgggagggcaagtcagaggaggcc gaccatgctgcagcctggcttacccaccagggcagtttccaaggggggttccgcagcacc caggacacagtgatagccttggacgctctgtctgcgtactggattgcttcccacaccccc gaagagagggtgctcaatgtaactctcagctccgtgggccgcagtgggttcaagtcccat gaactgcatctgaacaaccaccaaattcaggggctggaggaggagctgcagttctccttg ggcagcaagattaatgtgaaggtgggaggcaacagcaaagggaccttgaagatccttcgt acctataacgtcctggacctgaagaacacgacctgtgaggatcttcagattgaagtcacc gtcacgggccacgttgaatacacaagggaggccaacgaggactacgaggactatgtgtat gaggagcttccagccaaggacgacccgggtgccagttcccagaccgtgacgcccctggag ctgtttgagaggcggcggaatcgccgcaggcgggaggcgcccagggagcccgacgagcag gaatccagagtgcagtacaccgtgtgcatctggcggaacagccaggtggggctatcgggc atggccattgccgacatcaccctcctgagtggattcagcgccttgcgtgccgacctggag aagctggcctccctctctgaccgctatgtgagtcattttgagaccgaggggccccacgtc ctgctgtactttgactcggtccccacctcccgggagtgcgtgggcttcggggccgtgcag gaggtggccgtggggcttgtgcagccagccagcgcagccctgtatgattactacaacccc gagcgcacatgttctgtgttttacgcggcccccactaagagcaaactcttgtccacgttg tgctctgccgatgtctgccagtgtgctgaggggaagtgccctcgacagcgccgtgccctg gagcgggggctgcaggacgaggagggctacaggatgaagttcgcctgctactacccccgc gtgcagtacggcttccaggtgaaggtcctccgagaagatggcagagctgccttccgcctc tttgagaccagaatcacccaagtcctgcacttcaccaaggacaccaaggccacagtccat cagacccgaaacttcctggttcgagcctcttgccgccttcgcctggaacctgggaaagaa tatttgatcatgggtctggacggagctacctttgacctcaagggagacccccagtacctg ctggactcgaacacctgggtcgaggagatgccctctgaacgcctgtgccagagcacccgc catcgggcagcctgcgcccagctcagcgacttcctccaggagtacggcgctcaggggtgc caggtgtaa

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