Ursus americanus (American black bear): 123791662 Help Entry 123791662         CDS       T07931                                  Symbol PSEN2 Name (RefSeq) presenilin-2 isoform X1   KO K04522   presenilin 2 [EC:3.4.23.-] Organism uar  Ursus americanus (American black bear) Pathway uar04330   Notch signaling pathway uar04722   Neurotrophin signaling pathway uar05010   Alzheimer disease uar05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:uar00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     123791662 (PSEN2)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     123791662 (PSEN2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     123791662 (PSEN2)    05022 Pathways of neurodegeneration - multiple diseases     123791662 (PSEN2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uar01002]     123791662 (PSEN2) Peptidases and inhibitors [BR:uar01002]  Aspartic peptidases   Family A22: presenilin family    123791662 (PSEN2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Presenilin Motif Other DBs NCBI-GeneID:  123791662 NCBI-ProteinID:  XP_045652501 LinkDB All DBs Position Unknown AA seq 465 aa AA seqDB search MLTFMASDSEEEVCDERTSLMSAESPPPRCCQEARQGLEDGDNAAQWRSQDSEDDLDEDA DRYMCSGVPGQPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLP YGGGREQSLQPAISLSIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKHR CYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKG PLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQE RNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPP LPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTL LLLAVFRKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt atgctcacattcatggcctctgacagtgaggaagaagtgtgtgatgagaggacgtccctg atgtcagccgagagccccccgccgcgctgctgccaggaggcccggcagggcctggaggac ggagacaatgctgcccagtggagaagccaggatagcgaggatgaccttgacgaggacgcg gaccgctacatgtgcagtggggtccccgggcagccgtcaggcctggaagaggagctgacc ctcaaatacggggcgaagcacgtgatcatgctgtttgtgcccgtcaccctgtgcatgatc gtggtggtggccaccatcaagtctgtgcgcttctacacggagaagaacggccagctgccc tatggaggaggcagggagcagagtctgcagcccgccatctccctcagcatctacacacca ttcaccgaggacacgccctccgtgggccagcgcctgctcaactccgtgctcaacacgctc atcatgatcagcgtcatcgtggccatgaccatcttcctggtcgtgctctacaagcaccgc tgctacaagttcattcatggctggttgatcatgtcctccctgatgctgctgttcctcttt acctatatctacctcggggaagtgctcaagacctacaacgtggccatggactaccccacc ctgttcctgaccgtctggaactttggcgctgtggggatggtgtgcatccactggaaaggc cccctggtgctgcagcaggcctacctcatcatgatcagcgcgctcatggccttggtcttc atcaagtacctcccggagtggtccgcttgggtcattctgggcgccatctctgtgtatgat ctcgtggctgtgctgtgccccaaagggccgctgaggatgctggtggagactgcccaggag agaaacgagcccatatttcccgccctgatctactcctctgccatggtgtggacggtgggc atggccaagctggacccctcctcccagggagcccttcagctgccctacgaccccgagatg gaagaagactcctatgacagttttggggagccctcgtacccggaagtctttgagcccccc ctgcctggttacccaggggaggagctggaggaagaggaagaaaggggcgtgaagctcggc ctgggggacttcatcttctacagtgtgctggtgggcaaggcggcggccacgggcagcggg gactggaacaccacgctggcatgcttcgtggccatcctcattggtttgtgtctgaccctc ctgctgctggctgtgttcaggaaggcactgcccgccctccccatctccatcacgttcggg ctcatcttctacttctccacggacaacctggtgcgtccgttcatggacaccttggcttct catcagctctacatctga

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