Ursus americanus (American black bear): 123792172
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Entry
123792172 CDS
T07931
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar00590
Arachidonic acid metabolism
uar01100
Metabolic pathways
uar01523
Antifolate resistance
uar04726
Serotonergic synapse
uar04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
123792172 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
123792172 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
123792172 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123792172 (ALOX12)
Enzymes [BR:
uar01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
123792172 (ALOX12)
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Paralog
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
123792172
NCBI-ProteinID:
XP_045653367
UniProt:
A0A452S6K9
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All DBs
Position
Unknown
AA seq
663 aa
AA seq
DB search
MGRYRIRVATGAWLFSGSHNRVQLWLVGARGEAELQLHLRPARGQEEEFERDVPKDLGPL
QFVKLRKHHSLVDDAWFCDLITVRGPGACEEAAFPCYRWVQGQGVLSLPEGTARLAGDNA
LDVFQKHREKELKERQKLYCWDTWKEGLPLTIAAGCQDDLPPNMRFHEDKRLDFEWALKA
GALEMVLKRVYTLLSSWNRLEDFDQIFWGQKSALAEKVHQCWQDDELFGYQFLNGANPML
LRRSTSLPSRLALPPGMEALGAQLERELQNHSLFEADFILLDGIPANVIRGEKQYLAAPL
VLLKMTPNGKLLPLVIQIQPPSPSSPTPPLFLPSDPPLAWLLAKVWVRNSDFQLHQLQYH
LLNTHLVAEVIAVATMRRLPGLHPVFKLLIPHIRYTMEINTRARSQLISEGGIFDKTVST
GGGGHVQLLRRAVAQLTYCSLCPPDDLADRGLLGIPGALYAHDALRLWGIIARYVEGIVH
LFYHRDDVVRGDPELQAWCREITEVGLCQAQDRGFPVSFQSQKQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMTITWHLGRR
QPDMVPLGHHKEKYFSSPKAKAALNQFQTDLENLEREITARNEQLDLPYDYLKPSRIENS
VTI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatccgcgtggccaccggggcctggctcttctccggttcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaggcggagctgcagctgcacctgcgg
ccggcgcggggccaggaggaggagtttgagcgcgacgtccccaaggacttggggcccctg
cagttcgtgaagttgcgcaaacaccactccctggtggacgacgcatggttctgcgacctc
atcaccgtgcgcggcccaggagcctgcgaggaggccgccttcccctgctaccgctgggtg
cagggccagggcgtactgagcctgcccgagggcaccgcacgcctggcaggagacaatgcc
ctggacgtgttccagaagcatcgagagaaagaactgaaggaaagacaaaagctgtactgc
tgggacacctggaaggaggggttacccctgaccatagctgccgggtgtcaggacgatcta
cctccaaacatgagattccatgaggacaagaggctggacttcgagtgggcactgaaggcg
ggggcactggagatggtcctcaaacgtgtctacaccctcctgagctcctggaaccgcctg
gaggattttgatcagatcttctggggccagaagagtgccctggctgagaaggtccaccag
tgctggcaggacgatgagctttttggctaccagttcctcaatggcgccaaccccatgctg
ttgagacgctcaacctccctgccctcccggcttgcgctgcccccggggatggaggcactg
ggggcccagctggagagagagctccagaaccattccctgtttgaggctgacttcatcctg
ctggatggaattcccgccaacgtgatccggggcgagaagcagtacctggccgcccccctc
gtcctgctgaagatgacacccaatgggaagctgctgcccctggtcatccagatccagcct
cccagccccagctcccccaccccgccgctgttcctgccctcagatcccccactcgcctgg
ctcctggcaaaggtctgggtccgaaattccgatttccagctgcaccagctccagtatcac
ctgctgaacactcacctggtggccgaggtcatcgctgtggccaccatgaggcgcctcccg
gggctgcaccctgtcttcaagctcctgatcccacacatccgctacaccatggagatcaac
acccgggccagatcccagctcatctcagaaggaggaatatttgacaagacggtgagcaca
ggaggagggggccatgtacagttgctgcgtcgggccgtggctcagctgacctactgctcc
ctctgtcctcctgacgacctggctgaccggggcctgctgggaatcccaggagccctctat
gcccacgacgctttacggctctgggggatcatcgcccggtacgtggagggcatcgtccac
ctcttctaccacagggatgacgtcgtgagaggggacccggagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccaggcccaggaccgaggtttccctgtatccttccag
tcccagaagcagctctgccatttccttaccatgtgtgtcttcacatgcactgctcagcat
ggggccatcaaccagggccagctggactggtatgcctgggttcctaatgccccatgcaca
atgcggatgcccccacccaccaccaaggaagatgtaacaatggccacagtgatgggctca
ctacctgatgtccgtcaggcctgtcttcaaatgaccatcacgtggcatctgggtcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaagtacttctcaagccccaaggcc
aaggctgcattaaaccaattccaaacggatttggaaaacctagaaagagagattacagcc
cggaatgagcaactcgacctgccctatgactacctgaagcccagccgcatagagaacagc
gtcactatctga
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