Ursus americanus (American black bear): 123793926 Help Entry 123793926         CDS       T07931                                  Symbol HK3 Name (RefSeq) hexokinase-3 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism uar  Ursus americanus (American black bear) Pathway uar00010   Glycolysis / Gluconeogenesis uar00051   Fructose and mannose metabolism uar00052   Galactose metabolism uar00500   Starch and sucrose metabolism uar00520   Amino sugar and nucleotide sugar metabolism uar00524   Neomycin, kanamycin and gentamicin biosynthesis uar01100   Metabolic pathways uar01200   Carbon metabolism uar01250   Biosynthesis of nucleotide sugars uar04066   HIF-1 signaling pathway uar04910   Insulin signaling pathway uar04930   Type II diabetes mellitus uar04973   Carbohydrate digestion and absorption uar05230   Central carbon metabolism in cancer Module uar_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate uar_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc uar_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     123793926 (HK3)    00051 Fructose and mannose metabolism     123793926 (HK3)    00052 Galactose metabolism     123793926 (HK3)    00500 Starch and sucrose metabolism     123793926 (HK3)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     123793926 (HK3)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     123793926 (HK3)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     123793926 (HK3)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     123793926 (HK3)   09154 Digestive system    04973 Carbohydrate digestion and absorption     123793926 (HK3)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     123793926 (HK3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     123793926 (HK3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uar04131]     123793926 (HK3) Enzymes [BR:uar01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      123793926 (HK3) Membrane trafficking [BR:uar04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     123793926 (HK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  123793926 NCBI-ProteinID:  XP_045655994 LinkDB All DBs Position Unknown AA seq 990 aa AA seqDB search MPHIEREELKPEESDQLLLLPGGHPPLWNHMDSIGPVGLQQREGAPGCSQEGLPCPSDSS ELVLECLQQFKVTETQLQQIQASLLGSMEQALWGQATPASAVRMLPTYVGSTPHGTEQGD FVVLELGATGASLRVLWVTLMGTEGHRMEPQSQEFVIPPEVMLGPGQQLFDFAAHCLSEF LDALPMDKQGLQLGFSFSFPCHQTGLDRVRQSRHGDSGWKSCNPMKAVGGVTQLFCPQST LISWTKGFRCSGVEGHDVVQLLRDAIERQGAYSIDVVAVVNDTVGTMMGCEPGVGPCEIG LVVDTGTNACYMEEARHVAVLDEDRGRVCISVEWGSFSDDGVLGPVLTTFDHALDRESLN PGAQRFEKMIGGLYLGELVRLVLAHLAQRGVLFGGCTSPALLSRGSILLDHVAEMEDTLC PSSPLAGAARVHALLQDLGLSVGASDAELVQYVCAAVLTRAARLCAAALAAVLSRLQHSR EQQMLQIAVATGGRVFERHPSFLSVLQKTVMLLAPQCDVSFIPSVDGGGRGVAMVTAVAA RLAAHRRLLEETLAPFRLNHNQLAAVQAQMREAMVKGLRGEASSLRMLPTYVRATPDGTE RGDFLALDLGGTNFRVLLVRVTAGGVKITSQVYSIPEDVAQGSGQQLFDRIVDCIVDFQQ KQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFSASDCEGQDVVCLLREAIGRRQAV ELNVVAIVNDTVGTMMSCGYEDPRCEVGLIVGTGTNACYMEELRNVAAVAGDSGHMCINM EWGAFGDDGSLDLLRTCFDANVDQASINPGKQSFEKMISGMYLGEIVRHILLRLTSLGVL FRGQQTQRLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLPLTSDDALMVLEVCQAVS QRAAQLCGAGVAAVVEKIRENRGLEELTVSVGVDGTLYKLHPHFSGLVAATVRELAPRCE VTFLQSEDGSGKGAALVTAVACRLAQMARV NT seq 2973 nt NT seq  +upstreamnt  +downstreamnt atgcctcacattgagagagaagagctcaagcctgaggaaagtgaccaactgcttcttctc ccgggtggccaccctccattgtggaaccacatggactccattgggccagtagggttgcag caaagggaaggagctcctggctgctcccaggagggcttgccctgcccctcagacagctct gagctggtgctggagtgtctacagcaattcaaggtgacggagacacagctgcagcagatc caagccagcctcctgggctctatggagcaggcactgtgggggcaggccacccctgcctct gctgtccggatgctgcccacatacgtggggtccaccccacacggcactgagcaaggagat tttgtagtgctggagctgggggctacaggggcctcactgcgtgttctgtgggtgaccctg atgggcactgagggtcataggatggagccccagagccaggagtttgtgatccccccagag gtgatgctgggtcctggtcagcagctctttgactttgctgcccactgtctgtctgagttc ctggatgcactccccatggacaaacagggtctgcagcttgggttcagcttctccttccct tgtcaccagacgggcctggacagggtgaggcagagtcggcatggggacagtgggtggaag agttgtaaccccatgaaggctgttggaggagtgacccagcttttctgcccccagagcacc cttatttcctggaccaaaggttttaggtgcagtggtgtggaaggccacgatgtggtccag ttgctgcgagatgccatcgagaggcagggggcctacagcatcgatgtggttgccgtggtg aatgacacagtgggcaccatgatgggctgtgagccaggggttgggccgtgtgaaatcggg cttgttgtagacactggcaccaatgcatgttacatggaggaggcaaggcatgtggcagtg ctggatgaggaccggggccgcgtctgcatcagcgttgagtggggctccttcagtgatgat ggggtcctgggaccagtgctgaccacctttgaccatgccttggaccgagagtccctgaat cctggtgcccagaggtttgagaagatgattggaggcttgtacctgggtgagctggtgagg cttgtgttggctcacctggcccagcgaggggtcctctttggtggctgcacctcccctgcc ctgctgagccgaggcagcatcctcctggatcatgtggctgagatggaggataccctgtgt ccctccagccccttggctggggcagcccgtgtgcatgctctcctgcaggacttgggcctg agcgtgggggcctcggatgctgagctcgttcagtacgtatgtgcagccgtgttgactcgg gctgcccggctctgtgccgccgccctggctgctgttctctcccgcctccagcacagccgg gagcagcagatgcttcagattgctgtggccaccggaggccgagtgtttgagagacacccc agtttcctcagcgtcctgcagaagactgtgatgctcctggccccccaatgtgatgtctcc ttcattccctctgtggatgggggtggccggggcgtggcaatggtgactgctgtggctgcc cgtctggctgctcaccggcgcctgctggaagagaccttggcacctttccggttgaaccat aatcagctggcagcagtgcaggcacagatgcgggaggcaatggtcaaggggctccgaggg gaggcctcatccctccgcatgctgcccacttatgtccgggccacgcctgatggcactgag cgtggggacttcctggccctggacctggggggcaccaacttccgggtgctcttggtgcgc gtgacagcaggaggtgtgaagatcaccagccaggtctactccatcccggaggatgtggcc cagggctctggacagcagctcttcgaccgcatcgtggactgcattgtggacttccagcag aagcagggcctgagtgggcagagccttccgctgggtttcaccttctccttcccatgcagg cagctcggcctcgaccagggcatcctcctaaactggacaaaaggtttcagtgcatcagac tgtgagggccaagatgttgtgtgtctgctgcgggaagccatcgggcgaagacaggcagta gagctgaatgtggttgccattgtcaatgacacggtggggaccatgatgtcctgtggctat gaggatccccgttgcgaggtcggcctcatcgttggaactggcaccaatgcctgctacatg gaggagcttcggaatgtggcagctgtggctggggactcaggccacatgtgcatcaatatg gaatggggtgcctttggggatgatggctctttggacttgcttagaacctgctttgatgca aatgtggaccaggcatccatcaaccctggcaagcagagctttgagaagatgatcagtggc atgtacctaggggagatcgtccgccacattctcttgcgtttgaccagccttggagttctc ttccggggccagcagacccagcgccttcagaccagggacatcttcaagaccaagtttctc tctgagattgaaagtgacagcctggctctgaggcaggtccgagccatcctggaggatctg gggctgcccctgacctcagatgatgccctgatggtcctggaggtgtgccaggctgtgtcc cagcgggctgcccagctctgtggggcgggtgtggctgctgtggtggagaagatccgtgag aaccggggcctggaagagctgactgtgtccgtaggggtggatgggaccctctacaagctg cacccccacttctccggcctggtggcagccacggtgagggagctggcccctcgctgtgag gtcaccttcctgcagtcggaagatgggtccggcaaaggtgcagccctggtcactgcagtt gcctgccgtcttgcccagatggcccgtgtttga

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