Ursus americanus (American black bear): 123798221
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Entry
123798221 CDS
T07931
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04120
Ubiquitin mediated proteolysis
uar04144
Endocytosis
uar04330
Notch signaling pathway
uar04668
TNF signaling pathway
uar04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
123798221 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
123798221 (ITCH)
04668 TNF signaling pathway
123798221 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123798221 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
123798221 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
uar04131
]
123798221 (ITCH)
04121 Ubiquitin system [BR:
uar04121
]
123798221 (ITCH)
Enzymes [BR:
uar01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
123798221 (ITCH)
Membrane trafficking [BR:
uar04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
123798221 (ITCH)
Ubiquitin system [BR:
uar04121
]
Ubiquitin ligases (E3)
HECT type E3
123798221 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
123798221
NCBI-ProteinID:
XP_045662491
LinkDB
All DBs
Position
Unknown
AA seq
865 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGETTCSENVKGASQNDDGSRPKDETRTNT
NGSDEPEDAGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATS
ESDGSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNPIPQAPLPPGWEQRVDQ
HGRVYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYE
QWQLQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVN
HNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDN
GPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLW
VIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYF
RFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEE
CGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFF
EGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKE
IDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLP
PYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccgagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaagtgcaacaataca
aacagtcccaaatggaagcagccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccaacagagacaataggagacttgtcagtttgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaactacatgttcagaaaatgtt
aaaggtgcttcacagaatgatgatggctccagacccaaggatgaaacaagaacaaacaca
aatggatcagatgagcctgaagatgcaggagctggtgaaaataggaaggtcaatgggaat
aattctccatcactctcaaatggtggttttaaaccttctaggcctccaagaccttcacga
ccacctccacctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttct
gaaagtgatggatccagtacgggctctctgccaccaacaaatataaattcaaatacatct
gaaggagcaacatctgggttaataattcctctgactatatctggaggctcaggccctagg
ccattaaatcctatacctcaggctcccctaccacctggttgggagcagagagtggaccag
catggacgagtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaa
cctctacctcctggttgggaacggcgggttgacaacatgggacgtatttactatgttgac
catttcacaagaacaacaacatggcagaggccaacattggaatccgtccggaactatgaa
cagtggcagctacaacgtagtcagctgcaaggagcaatgcagcagtttaaccagagattt
atttatgggaatcaagatttgtttactacatcacaaaataaagaatttgatccccttggt
cccctgccacctggatgggagaagagaacagacagcaatggtagagtatattttgtcaac
cataacactcgtattacgcaatgggaagaccccagaagtcaaggtcagttaaatgaaaaa
cctttacctgaaggctgggaaatgagattcacagtcgatggaattccatattttgtggac
cacaatagaagaacaactacctatattgatccccgcactggaaaatctgccctagacaat
ggaccacagatagcctacgtacgggacttcaaggcaaaagttcagtatttccggttctgg
tgtcagcaactggccatgccacagcacataaagattacggtgacaagaaagacattgttt
gaagattcctttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgg
gtgatttttccaggagaagaaggtttagattatggaggtgtagcaagagagtggttcttt
cttttgtcacatgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggat
aactactgcttgcagattaatcctgcttcttacatcaatccagatcacctgaaatatttt
cgttttattggcaggtttattgccatggctctgttccatgggaaattcatagacacaggt
ttttctttgccattctataagcgtatattgaacaaaccagttggactcaaggatttagaa
tctattgatccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaa
tgtggtctggaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcat
gatttgaaacctaatggtggcaatattcttgtgacagaagaaaataaagaggaatatatc
agaatggtagctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttcttt
gagggctttaatgaaattcttccccagcagtatttgcaatactttgatgcaaaggagtta
gaggtccttttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatc
taccgtcattacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaa
attgataatgagaagagaatgagacttctgcagtttgttactggaacctgcagattgcca
gttggaggatttgctgacctcatggggagcaatggaccacaaaaattctgcattgaaaaa
gttgggaaagaaaactggttacccagaagtcatacgtgttttaaccgcctggacctgcca
ccctacaagagctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaa
ggatttggacaagagtaa
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