Ursus americanus (American black bear): 123798269
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Entry
123798269 CDS
T07931
Symbol
ERBB4
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4 isoform X1
KO
K05085
receptor tyrosine-protein kinase erbB-4 [EC:
2.7.10.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04010
MAPK signaling pathway
uar04012
ErbB signaling pathway
uar04020
Calcium signaling pathway
uar04151
PI3K-Akt signaling pathway
uar05014
Amyotrophic lateral sclerosis
uar05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123798269 (ERBB4)
04012 ErbB signaling pathway
123798269 (ERBB4)
04020 Calcium signaling pathway
123798269 (ERBB4)
04151 PI3K-Akt signaling pathway
123798269 (ERBB4)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
123798269 (ERBB4)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
123798269 (ERBB4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123798269 (ERBB4)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123798269 (ERBB4)
Protein kinases [BR:
uar01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
123798269 (ERBB4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
DUF3951
ABC1
Motif
Other DBs
NCBI-GeneID:
123798269
NCBI-ProteinID:
XP_045662605
LinkDB
All DBs
Position
Unknown
AA seq
1308 aa
AA seq
DB search
MKLATGLWVWVSLLLAAGTVQPNASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAVF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVST
NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMAAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
INQRIVIRDNRKAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGRSCIESCNLYD
GEFREFENGSICVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCSGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG
LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR
VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL
VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV
HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ
SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID
ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE
EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVPVP
YRATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERS
PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED
EYVNEPLYLNTFANALGNAEYLKNHVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ
EYSTNYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq
3927 nt
NT seq
+upstream
nt +downstream
nt
atgaagctggcgacaggactgtgggtctgggtgagccttctcctggcagcagggaccgtc
cagcccaacgcttctcagtcagtgtgtgcaggaacagaaaacaagctgagctctctctct
gacctggagcagcagtaccgagccttgcgcaaatactatgagaactgtgaggtcgtcatg
ggcaacttggagataaccagcatcgagcacaaccgggacctctcctttctgcggtctatt
cgagaagtcacaggctacgtgttagtggctcttaaccagtttcgttacctgcctctggag
aatttacgcattattcgtgggacaaaactctatgaggatcgatatgccttggcagtattt
ctaaactacagaaaagatgggaactttggacttcaagaacttgggctgaagaacttgaca
gaaatccttaatggtggagtgtacgtagaccagaacaaatttctttgttacacagacaca
attcattggcaagatattgttcggaatccatggccttccaacttgactctggtgtcaaca
aatggtagctcaggatgtggacgttgtcataagtcctgtactggccgatgctggggaccc
acagaaaatcattgccagaccttgacaaggacggtgtgtgcagagcagtgtgatggcagg
tgctatgggccctatgtcagtgactgctgtcatagagaatgtgctgggggctgctcggga
ccgaaggacacagactgctttgcctgcatgaatttcaatgacagtggagcatgtgttact
cagtgtccccaaacttttgtctacaatccaaccacctttcaactggagcataacttcaat
gcaaagtatacatatggagcattttgtgtcaagaaatgcccacataactttgtggtggat
tccagttcttgtgtgcgtgcctgccctagttccaagatggaagtagaagaaaatgggatt
aaaatgtgtaaaccttgcacggatatttgcccaaaagcttgtgatggtattggcacagga
tcactgatggcagctcagaccgtggattccagtaacattgacaaattcataaactgcacc
aaaatcaatgggaatttgatcttccttgtcactggtattcatggggacccttacaacgca
attgaagccatagacccagagaaactgaatgttttccggacagttcgagagataacaggt
ttcttgaacatacagtcatggcccccaaacatgactgacttcagtgttttctctaacctg
gtgaccatcggtggaagagtcctctatagtggcctctccttgcttatccttaagcaacag
ggcatcacttctctacaattccagtctctgaaggaaatcagtgcaggaaacatctatatt
actgacaacagcaacctatgttattatcataccattaattggacaacactcttcagcact
atcaaccaaagaatagtgatccgggacaataggaaagctgaaaactgtactgctgaagga
atggtgtgcaaccatctgtgttcaaacgatggctgttggggacctggccccgaccagtgc
ctgtcctgccgtcgtttcagcagaggaaggagctgcatcgagtcttgtaacctctatgat
ggtgaatttcgagagtttgagaatggctccatctgtgtggagtgtgacccccagtgtgag
aagatggaagatggcatcctcacctgccatggaccgggacctgacaactgcacaaagtgc
tcccattttaaagatggtccgaactgtgtggaaaaatgtccagatggcctacagggggca
aacagtttcattttcaagtatgctgatcaggatcgggagtgccacccatgccatccaaac
tgcacccaagggtgtagcggtcccactagtcatgactgcatttattatccttggacgggc
cattccactttaccacaacatgctagaactccgctaattgcagcgggagttattggcggg
ctcttcatcctggtcatcgtgggtctaacatttgcagtttatgttagaaggaagagcatc
aaaaagaaaagagccttaagaagatttctggaaacagagttagtagaacccttaactccc
agtggtacggcacccaatcaagctcaacttcgtattttaaaagaaacggagctcaaaaga
gtgaaagtactcggctcaggtgcttttggaacagtttataagggtatttgggtacctgaa
ggagaaacagtaaagattcctgtggctattaagattcttaatgaaacaactggtcccaaa
gccaatgtagagttcatggatgaagctttgatcatggcaagtatggatcatccacactta
gtccggttattgggtgtgtgtctgagcccaaccattcagctggttacacagcttatgccc
catggctgcctgttggattatgtccacgaacacaaggacaacattggatcccagctgctg
cttaactggtgtgtccagatagctaagggaatgatgtacttggaagaaagacggcttgtt
catcgggatttggcagcccgaaatgtcttagtgaaatctccaaaccatgtgaaaatcaca
gattttggactagccagactcttagaaggagatgaaaaagagtataatgctgatggagga
aagatgccaattaaatggatggctctggagtgtatacactacaggaaattcacccatcag
agtgatgtttggagctacggagtcactatatgggaactgatgacctttggaggaaaaccc
tacgatggaattccaacccgagaaatcccggatttattagagaaaggcgaacgtttgccc
cagcctccaatctgcactattgacgtttacatggtcatggtcaaatgttggatgattgat
gctgacagtaggcctaaatttaaggaactggctgctgaattttcgaggatggcacgagac
cctcaaagatatctcgttattcagggtgatgatcgcatgaagcttcccagtccaaacgac
agcaagttctttcagaatctcttggatgaagaggatttggaagacatgatggatgctgag
gaatacctcgtccctcaggctttcaacatcccacctcccatctatacttccagagcgaga
attgactcaaataggagtgaaattggacacagccctcctcctgcctacacccccatgtca
ggaaaccagtttgtataccgagatggaggttttgctgcagagcaaggagtacctgtgccc
tacagagccacgaccagcacgatcccagaagctccagttgctcagggggctacagccgag
atgtttgatgactcctgttgtaacggcaccctacgcaagccagtggcaccccacgtgcag
gaggacagcagcacccagaggtacagcgcggaccccaccgtctttgcgccggaacggagc
ccacgaggagagctggatgaagaaggttacatgacccctatgcgagataaacctaaacaa
gaatacctgaaccctgtggaggagaacccttttgtttctcggaggaaaaacggagacctt
caagctttggataatcccgaatatcacaatgcttccaatggtccacccaaggcagaggat
gagtacgtgaacgagccactgtacctcaacacctttgccaacgcgttggggaatgccgag
tacctgaagaaccatgtactgtctgtgccagagaaggccaagaaagcattcgacaaccct
gactactggaaccacagcctgccacctcggagcacccttcagcacccagactacctgcag
gagtacagcacaaactatttttataaacaaaatggacggatccggcctattgtggcagag
aatcctgaatacctctctgagttctcgctgaagccaggcacggtgctgcctcctccaccc
tacagacaccgaaatactgtggtgtaa
DBGET
integrated database retrieval system
