Ursus americanus (American black bear): 123799411 Help Entry 123799411         CDS       T07931                                  Symbol TRAF6 Name (RefSeq) TNF receptor-associated factor 6   KO K03175   TNF receptor-associated factor 6 [EC:2.3.2.27] Organism uar  Ursus americanus (American black bear) Pathway uar04010   MAPK signaling pathway uar04064   NF-kappa B signaling pathway uar04120   Ubiquitin mediated proteolysis uar04140   Autophagy - animal uar04144   Endocytosis uar04380   Osteoclast differentiation uar04620   Toll-like receptor signaling pathway uar04621   NOD-like receptor signaling pathway uar04622   RIG-I-like receptor signaling pathway uar04657   IL-17 signaling pathway uar04722   Neurotrophin signaling pathway uar04936   Alcoholic liver disease uar05132   Salmonella infection uar05133   Pertussis uar05135   Yersinia infection uar05140   Leishmaniasis uar05142   Chagas disease uar05145   Toxoplasmosis uar05152   Tuberculosis uar05160   Hepatitis C uar05161   Hepatitis B uar05162   Measles uar05168   Herpes simplex virus 1 infection uar05169   Epstein-Barr virus infection uar05170   Human immunodeficiency virus 1 infection uar05171   Coronavirus disease - COVID-19 uar05200   Pathways in cancer uar05222   Small cell lung cancer uar05235   PD-L1 expression and PD-1 checkpoint pathway in cancer uar05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:uar00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     123799411 (TRAF6)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     123799411 (TRAF6)    04064 NF-kappa B signaling pathway     123799411 (TRAF6)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     123799411 (TRAF6)    04140 Autophagy - animal     123799411 (TRAF6)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     123799411 (TRAF6)    04621 NOD-like receptor signaling pathway     123799411 (TRAF6)    04622 RIG-I-like receptor signaling pathway     123799411 (TRAF6)    04657 IL-17 signaling pathway     123799411 (TRAF6)   09156 Nervous system    04722 Neurotrophin signaling pathway     123799411 (TRAF6)   09158 Development and regeneration    04380 Osteoclast differentiation     123799411 (TRAF6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123799411 (TRAF6)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     123799411 (TRAF6)   09162 Cancer: specific types    05222 Small cell lung cancer     123799411 (TRAF6)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     123799411 (TRAF6)    05161 Hepatitis B     123799411 (TRAF6)    05160 Hepatitis C     123799411 (TRAF6)    05171 Coronavirus disease - COVID-19     123799411 (TRAF6)    05162 Measles     123799411 (TRAF6)    05168 Herpes simplex virus 1 infection     123799411 (TRAF6)    05169 Epstein-Barr virus infection     123799411 (TRAF6)   09171 Infectious disease: bacterial    05132 Salmonella infection     123799411 (TRAF6)    05135 Yersinia infection     123799411 (TRAF6)    05133 Pertussis     123799411 (TRAF6)    05152 Tuberculosis     123799411 (TRAF6)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     123799411 (TRAF6)    05140 Leishmaniasis     123799411 (TRAF6)    05142 Chagas disease     123799411 (TRAF6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     123799411 (TRAF6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     123799411 (TRAF6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uar04131]     123799411 (TRAF6)    04121 Ubiquitin system [BR:uar04121]     123799411 (TRAF6) Enzymes [BR:uar01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      123799411 (TRAF6) Membrane trafficking [BR:uar04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     123799411 (TRAF6) Ubiquitin system [BR:uar04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     123799411 (TRAF6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TRAF-mep_MATH MATH_2 zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-RING_UBOX zf-RING_2 zf-C3HC4_3 zf-C3HC4_4 zf-TRAF_2 zf-RING_5 SlyX TRAF3_RING RING_XB3-XBAT31 U-box zf-RING_11 Spc29 DUF16 DUF4455 PspA_IM30 DUF3450 Myosin_tail_1 Laminin_II EzrA Sina_ZnF DUF7310 UPF0242 Med21 CENP-F_leu_zip ATG16 TMF_DNA_bd Motif Other DBs NCBI-GeneID:  123799411 NCBI-ProteinID:  XP_045664444 LinkDB All DBs Position Unknown AA seq 541 aa AA seqDB search MSLLNCENSCGSSQSESDCCAAMASSCSAAAKDDSVSGTASTGNLSSSFMEEIQGYDVEF DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMNCPQCQRPFQKCQLNIHILK ECPRRQVSCMNCAALMAFEDKEMHDQNCPLANVICEYCNTMLIREQMPNHYDLDCPTAPI PCTFSTFGCHVKMQRNHLARHLQENTQSHMRMLAQAVQSLSLALAPVPQRDMPPYDSSSV SRVSTPCHPEVHNFQETIQQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKV AEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQ RCANYISLFVHTMQGEYDSHLPWPFQGTIRLAILDQSEAPVRQNHEEIMDAKPELLAFQR PTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDSG T NT seq 1626 nt NT seq  +upstreamnt  +downstreamnt atgagtctgctaaactgtgaaaacagctgtggatccagccagtctgaaagtgactgctgt gccgccatggccagctcctgtagcgctgcagcaaaagatgacagtgtgagtggaaccgcc agcacggggaacctctccagctcttttatggaagagatccaggggtacgatgtggagttt gacccacccctagaaagcaagtatgaatgtcccatctgcctgatggcgttacgggaagcg gtacaaacaccatgtggccacaggttctgcaaagcttgcatcatcaaatcaataagggat gctggtcacaaatgtccagttgacaatgaaatattgctggaaaatcaactatttcctgac aattttgcaaaacgagagattctttctctgatggtgaagtgtccaaatgaaggttgtttg cacaagatggaactgaggcatcttgaggatcaccaagcacattgtgagtttgctctcatg aattgtccccagtgccaacgtcccttccaaaaatgccaacttaatattcacattcttaag gagtgcccaaggagacaagtttcttgcatgaactgtgctgcgttgatggcatttgaagat aaagagatgcatgaccagaactgtcctttggcaaatgtcatctgtgaatactgcaatacc atgctcatcagagaacagatgcctaatcactatgatctagactgtccaacagccccaatt ccatgcacattcagtactttcggttgccatgtaaagatgcagaggaatcacttggcacgc cacctacaagagaatacgcagtcgcacatgagaatgttggctcaggctgttcagagttta agtcttgctttagctcctgtacctcagcgtgatatgccgccgtatgattcttcctctgtg tcccgggtctctactccgtgtcacccagaggtccataatttccaagaaaccattcagcag ttagagggtcgcctcgtaagacaagaccatcaaatccgagagctgactgctaaaatggaa actcagagcatgtatgtaagtgagctcaagcgaactattcgaacccttgaagacaaagtt gctgaaatagaggcgcagcagtgcaacggcatctacatctggaagatcggcaactttggg atgcatttgaagtctcaggaagaggagaaacctgttgtcattcacagccctggattctac acaggcaaacccggctacaaactgtgcatgcgcctgcacctgcagttaccgaccgctcag cgctgcgctaattatatatccctctttgtccacaccatgcaaggggagtatgacagccac ctcccttggcccttccagggtacaatacgccttgcaattcttgatcagtctgaagcacct gtaaggcaaaaccatgaagagatcatggatgccaaaccagagctgcttgccttccagaga cccacaatcccacggaacccaaaaggttttggctatgtgacttttatgcatctggaagcc ctaagacaaagaaccttcattaaggatgatactttactagtacgctgtgaggtctctacc cgcttcgacatgggcagtctccggagggagggttttcagccacgaagtactgattcgggg acatag

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