Ursus americanus (American black bear): 123800367
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Entry
123800367 CDS
T07931
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04010
MAPK signaling pathway
uar04020
Calcium signaling pathway
uar04151
PI3K-Akt signaling pathway
uar05200
Pathways in cancer
uar05216
Thyroid cancer
uar05223
Non-small cell lung cancer
uar05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123800367 (RET)
04020 Calcium signaling pathway
123800367 (RET)
04151 PI3K-Akt signaling pathway
123800367 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123800367 (RET)
05230 Central carbon metabolism in cancer
123800367 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
123800367 (RET)
05223 Non-small cell lung cancer
123800367 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123800367 (RET)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123800367 (RET)
Protein kinases [BR:
uar01001
]
Receptor tyrosine kinases (RTK)
RET family
123800367 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
123800367
NCBI-ProteinID:
XP_045665976
LinkDB
All DBs
Position
Unknown
AA seq
1117 aa
AA seq
DB search
MAKATATAGAAGLRLLLLLPLLGEAPLGLYFSRDAYWEKLYVDQPAGMPLLYVHALRDVP
EEVPSFRLGQHLYGIAYRARLHENDWIRIEEDTGLLYLNRSLDHSAWEKLSIRNGGFPVL
TIYLQVFLSSASLREGECQWPGCARVYFSFINTSFPACSSLKPRELCFPETGVSFRIREN
RPPGTFHQFRLLPVQFLCPNISVSYRLLEGENLPFRCAPDSLEVSTRWALDRELREKYEL
VAACTVRVGARKEEVVMVPFPVTVYDEDDSAPTFLGGFDTASAVVEFKRKEGTVVATIRV
FDADVVPASGELLRRYTSTLLPGEPWALQTFRVEHSPNETLVQANGSFVRATVHDYRLVL
NRSLPISESRSLQLAVLVNDSDFQGPGEGVLLLHFNVTVLPVSLHLPSAYSFTVSKRARR
FAQIGKVCVDNCQEFSGIHVQYKLQLSSTNCSVLGVVTSAEDTTGTLFVNDTEALQRLDC
SQLQYTVVAADRPTRRQTQAPLVVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLGSLT
GRCEWRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRNVNICPQDCLRGGSIIGGHEPG
DRWGIKAGFGICNCFPEEKKCFCEPEDSQDPLCDELCRTVIAAAVLFSFIISMLLSTFCI
HRYHKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKIPEDPKW
EFPRKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFN
LLKQVNHPHVIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRSSSY
LDNPEERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSR
DVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP
ERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDYLD
LAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESPVPL
TRADGTNTVCPRYANDRVYANWMVSPSAAQLTDAFDS
NT seq
3354 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggcgacggccggcgccgcggggctgcggttgctgctgctgctgccg
ctgctcggcgaagctccactgggactctacttctccagggatgcttactgggagaaactg
tacgtggaccagccggctggcatgcccctgctctacgtccatgctctgcgggacgtcccc
gaggaggtgcccagcttccgcctgggccagcatctctacggcatcgcctaccgtgcaagg
ctgcatgagaacgactggatccgcatcgaggaggacacaggccttctctaccttaaccgg
agcctggatcacagcgcctgggagaagctcagcatccgcaatggcggcttccctgtgctc
accatctacctccaggtcttcctgtcgtctgcgtccctgcgtgagggcgagtgccagtgg
ccaggctgtgcccgtgtgtacttctcctttatcaacacctccttcccagcttgcagttct
ctcaaaccccgggagctctgctttcctgagacaggtgtctccttccgcatcagagagaac
aggcctcctggcaccttccaccaattccggctgctgcctgtgcagtttctctgccccaac
atcagtgtgtcctacaggctcctagaaggtgagaatctgcccttccgttgcgccccggac
agcctggaggtgagcacacgctgggccttggaccgcgagctgcgggagaagtatgagctg
gtggccgcgtgcacggtgcgcgtcggcgcgcgcaaggaggaggtggtgatggtgcccttc
cctgtgaccgtgtacgatgaggacgactcggcgcccaccttcctcgggggcttcgacacc
gccagcgctgtggtggagttcaagaggaaggagggcactgtggtggccacaatacgtgtc
ttcgacgcagatgtggtgccagcatctggggagctcctgaggagatacacaagcacacta
ctccctggggagccctgggccctccagacattccgtgtcgagcactcacccaacgagacc
ttggtccaggccaatggcagctttgtgcgggcaactgtgcacgactacaggctggttctc
aaccggagcctccccatctcggagagccgctccctgcagctggccgtgctggtcaatgac
tcggacttccagggccccggggagggtgtcctcctcctccacttcaacgtgaccgtgctg
cctgtcagcctgcacttacccagcgcctactccttcactgtgagcaagcgggcccgccgc
tttgcccagattgggaaagtctgtgtggacaactgccaggagttcagcggcatccacgtg
cagtacaagctgcagctctccagcaccaactgcagtgtcctgggggtggtcacctcagcc
gaggacaccacggggaccctgttcgtgaatgacacggaagccctgcagcggctcgattgt
tctcaactccagtacacggtggtggctgccgaccggccaacccgcaggcagacccaggcc
ccgctggtcgtcaccgtggaggggacgtatgtggctgaggagccaggctgccctctgtcc
tgtgcagtcagcaagaggcggcctgagtgtgaggagtgcggcggcctgggctctctgacg
ggcaggtgcgagtggagacagggagatggcaaagggatcacgaggaacttctccacctgc
tcccccagcatcaagacctgccccgatggccactgtgatgctgtggagagcagaaatgtc
aacatctgcccccaggactgcctcaggggcggcagcatcattggtgggcacgagccaggg
gaccgctgggggataaaagctggcttcggtatctgcaactgtttccctgaagagaagaag
tgcttctgtgagcctgaagacagccaggacccactgtgtgacgagctctgccgcacagtg
atcgcggcggccgtgctcttctccttcatcatctccatgctgctctccaccttctgcatc
caccgctaccacaagaacgcccacaagccgcccatcgcctccgctgagatgaccttccgc
cggccggcccaggccttcccagtcagttactcctcgtcgggtgcccgccggccctccctg
gactccatggagaaccaggtctctgtggatgccttcaagatcccggaggatccaaagtgg
gaattccctcggaagaacttggttcttggaaaaactctgggagaaggtgaatttggaaaa
gtggttaaggcaaccgccttccggcttaaaggcaaagcagggtacacaaccgtggccgtg
aagatgctgaaagagaacgcctccccaagcgagctgcgggacctgctgtcagagttcaac
ctcctgaagcaggtcaaccacccacatgtcatcaagctgtacggggcctgcagccaggat
gggccactcttcctcattgtggagtacgccaagtacggctccctgcggggattcctccga
gagagccgcaaggccgggccgggctacgtgggcagtggaggcagccgcagctccagctac
ctggacaaccccgaggagcgggccctgaccatgggtgacctcatctccttcgcctggcag
atctctcgggggatgcggtacctggcggagatgaagcttgtccatcgggacttggctgcc
agaaatgtcctggtagccgaggggcggaagatgaagatttcagattttggcctatcccga
gatgtttatgaagaggattcctatgtgaagaggagcaagggtcggattccagtcaaatgg
atggcaattgagtctcttttcgatcatatctacaccacccagagtgatgtgtggtccttc
ggtgtcctgctgtgggagattgtgactctggggggcaacccctacccggggattcctcca
gagcggctcttcaaccttctgaagacaggctaccggatggagaggcctgacaactgcagt
gaggagatgtatggtctaatgctgcagtgttggaagcaggaaccagacaagaggccggtg
tttgctgacatcagcaaagacctggagaagatgatggttaagaacagagactacttggac
ttggccgcgtccaccccatctgactccctgctttacgacgatggcctctcagaggaggag
acgcccctggtggactgtaataatgctcccctccctcgagcccttccctccacgtggatt
gaaaacaaactctatggcatgtcagacccgaactggcctgaagagagtcctgtaccactc
acgagagctgatggcactaacactgtgtgtccacgatatgcaaatgatagggtatatgct
aactggatggtttcaccctcagcggcacaattaacggacgcgtttgatagttaa
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integrated database retrieval system
