KEGG   Ursus americanus (American black bear): 123803006
Entry
123803006         CDS       T07931                                 
Name
(RefSeq) angiotensin-converting enzyme
  KO
K01283  peptidyl-dipeptidase A [EC:3.4.15.1]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04614  Renin-angiotensin system
uar04924  Renin secretion
uar05142  Chagas disease
uar05171  Coronavirus disease - COVID-19
uar05410  Hypertrophic cardiomyopathy
uar05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uar00001]
 09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    123803006
   04614 Renin-angiotensin system
    123803006
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    123803006
  09174 Infectious disease: parasitic
   05142 Chagas disease
    123803006
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    123803006
   05415 Diabetic cardiomyopathy
    123803006
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:uar01002]
    123803006
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:uar04147]
    123803006
   04090 CD molecules [BR:uar04090]
    123803006
Enzymes [BR:uar01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.15  Peptidyl-dipeptidases
    3.4.15.1  peptidyl-dipeptidase A
     123803006
Peptidases and inhibitors [BR:uar01002]
 Metallo peptidases
  Family M2
   123803006
Exosome [BR:uar04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   123803006
CD molecules [BR:uar04090]
 Proteins
  123803006
SSDB
Motif
Pfam: Peptidase_M2
Other DBs
NCBI-GeneID: 123803006
NCBI-ProteinID: XP_045670068
LinkDB
Position
Unknown
AA seq 1307 aa
MGAASGRPGQGLLPLPLLLLLLPPPAALALDPDLQPGNFAADEAGAQLFVQSFNSSAELV
MYQSTVASWAFDTNITEENARRQEEAALLNQEFAEVWGQKAKELYDPIWQNFSDPILRRV
ISGVRTLGPANLPVEKRQQYNSLLSNMNKIYSTARVCFYPNKTAICWSLDPELTHIMAIS
RNYALLLYAWEGWHNAVGTPLKPLYQNFTALSNEAYQKDGFSDTGAYWRSWYESPTFVED
LERLYHQVEPLYLHLHAYVRRALHRRYGDTYINLRGPIPAHLLGDMWAQSWDNLYDMMVP
FPDKPSLDVTSTMVRKGWNTTHMFRVAEEFFTSLGLSPMPPEFWAGSMLEKPTDGREVVC
HASAWDFYNRRDFRIKQCTRVTMDQLSTVHHEMGHVQYYLQYKEQPVSLRQGANPGFHEA
IGDVLALSVSTPAHLYKIGLLDNVSNDMESDINFLLKMALEKIAFLPFGYLVDQWRWGVF
SGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQ
FHQALCKEAGQQYPLHKCDIYQSTQAGAKLREALRAGSSRPWQEVLKEAIGSDTLDAQPL
LDYFQPVHQWLREQNERNGEVLGWPEYQWRPPMPNNYPQDIGLVTDEVEARRFVEEYDRR
SQVIWNEYAEANWNYNTNITTEASKILLQKNIQMANHTFKFGTWARQFDVTNFQNASIKR
MIKKIQDLERAALPAKELEEYNQILLDMETTYSVASVCHPNGTCLQLEPDLTSLMATSRK
YEDLLWAWKSWRDKVGRAILPFFPKYVELANKAARLNGYEDAGDSWRDMYEMPSLEQDLE
QLFQELQPLYLNLHAYVRRALHRHYGPQHINLEGPVPAHLLGNMWAQTWSNIYDLVVPFP
SAPKIDATEAMIKQGWTPKRMFEEADNFFTSLGLLPVPFEFWNKSMLEKPTDGREVVCHA
SAWDFYNGKDFRIKQCTTVNMEDLVVAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIG
DVLALSVSTPKHLHSINVLSSESGGYEQDINFLMKMALDKIAFVPFSYLVDQWRWRVFDG
SITKENYNQEWWNLRLKYQGLCPPVARSQGDFDPGAKFHVPSSVPYIRYFVGFVIQFQFH
EALCQAAGHKGPLHTCDIYQSKEAGKRLADAMKLGFSKPWPEAMKLITGQSNMSASAMMN
YFKPLLDWLLTENGRHGEKLGWPQYNWTPNSARSEGPFLGTGRVNFLGLDLEEQQARVGQ
WVLLFLGVALLVATLGLTQRLFSIRHHSLRRPHRGPQFGSEVELRHS
NT seq 3924 nt   +upstreamnt  +downstreamnt
atgggggccgcgtccggccgtccagggcaggggctgctgccgctgccgttgctgctgctg
ctgctgccgccgcccgccgccctggcgctcgaccccgacctgcagcccggaaactttgcc
gccgacgaggccggggcgcagctcttcgtgcagagcttcaactcgagcgccgagctggtg
atgtaccagagcacggtcgccagctgggcgttcgacaccaacatcaccgaggagaacgcg
cggcgccaggaggaagcagccctgctcaaccaggagtttgctgaggtctggggccagaag
gccaaggagctctatgacccaatctggcagaacttcagcgacccgatcctgcgaagggtc
atcagtggtgtgcgcaccctgggccctgccaacctgcctgtggaaaagcggcagcagtac
aactctctgctaagcaacatgaacaagatctactccacagctagggtctgcttctatccc
aacaagactgccatctgctggtccctggacccagagctcacccacatcatggccatctca
agaaactacgccctgctgctctatgcctgggagggctggcacaatgcggtgggcaccccg
ctgaagcccctgtaccagaacttcaccgccctcagcaatgaggcttaccagaaggatggc
ttctcagacacaggggcctactggcgctcctggtatgagtcacccaccttcgtggaggat
ctggagcgtctctaccatcaagtggagcccctctacctgcacctccatgcctacgtccgg
cgcgcactgcaccgccgatatggagacacatacatcaacctcaggggacccatccctgct
cacctgctgggggacatgtgggcccagagctgggacaacctctatgacatgatggtgcct
ttccctgacaagccgagcctcgatgttaccagtactatggtgcggaagggctggaacact
acacacatgttccgggtggcagaggagttcttcacctccctagggctctcgcccatgcct
cccgagttttgggcagggtccatgctggagaaaccaacagacgggcgtgaggtggtgtgc
catgcctctgcctgggacttctacaacaggagagacttcaggatcaagcagtgcacgcgg
gtcactatggaccagctgtccacggtgcaccacgagatgggccacgtgcagtactatctg
cagtacaaggagcagcctgtctccctgcgccaaggggccaaccctggcttccacgaggcc
atcggggatgtgctggcgctctccgtctccactcctgcacatctgtacaaaattggccta
ctggacaatgtcagcaatgacatggaaagtgacatcaatttcttgttaaagatggcattg
gaaaaaattgccttcctgccctttggctacttggtagaccagtggcgttggggggtcttt
agtgggcgtacccccccttcccgctacaactttgactggtggtatcttcgaaccaagtat
caggggatctgtcctccagttgcccgaaatgaaacccactttgatgcgggagctaagttt
catgtcccaaatgtgacaccgtacatcaggtactttgtgagttttgtcctgcagttccag
ttccatcaagccctgtgcaaggaggcaggccagcagtacccactgcacaagtgtgacatc
taccagtccacccaggcaggggccaagctccgggaggcgctgcgggcgggctcgtcacgg
ccctggcaggaggtgctaaaggaggcgattggctcggacaccctggacgctcagccactg
ctcgactacttccagccggtccaccagtggctgcgggagcagaacgagcgcaacggggag
gtgctggggtggccagagtaccagtggcggccaccgatgcccaacaattacccgcaggac
atcggcctggtgaccgatgaggtggaggccagaaggtttgtggaggaatatgaccgaaga
tcccaggtgatatggaatgaatacgccgaggctaattggaattataacaccaacatcacc
acagaggccagcaagatcctgctgcagaagaacatacagatggcaaaccacaccttcaag
ttcggcacctgggccaggcagttcgatgtgactaacttccagaacgccagcatcaagcgg
atgataaagaagattcaggacctagagcgggcagcgctgcctgccaaggagctggaggag
tataaccagatcctgctggacatggaaaccacctacagcgtggcctctgtgtgccacccc
aacggcacttgtctgcagctggagcctgatctgacgagtctgatggccacgtcccggaaa
tacgaagatctgttgtgggcctggaagagctggcgagacaaggtggggagagccatcctc
cctttcttccctaaatacgtggaacttgccaacaaggccgccaggctcaacggctacgaa
gacgcaggggactcctggagagacatgtatgagatgccgtccctggagcaagatctggag
cagctgttccaggagctgcagccgctctacctgaacctgcatgcctacgtgcgccgcgcc
ctgcaccgccactacgggccccagcacatcaacctggagggccccgttcccgctcacctg
ctggggaacatgtgggctcagacctggtccaacatctatgacttggtggtgcccttccct
tcagcccccaagatagatgccacagaggccatgataaagcagggctggacacccaaaagg
atgtttgaagaagcagacaatttcttcacctccctggggctgttgcccgtgccctttgag
ttctggaacaagtcaatgctggagaagccaaccgacgggcgggaagtagtgtgccatgcc
tctgcctgggacttctacaatggcaaggacttcaggatcaagcagtgcaccacggtgaac
atggaggacctggtggtggcccatcacgaaatgggccacatacagtatttcatgcagtac
aaggacttgcctgtgaccttccgggagggtgccaaccctggctttcacgaggccatcggc
gatgtgctggcgctttccgtgtctacgcccaagcacctacacagtatcaacgtactgagt
agcgagagcggtggctacgagcaagacatcaattttctgatgaagatggcactcgacaag
atcgcctttgtccccttcagctacctcgtcgaccagtggcgctggagggtattcgatgga
agcatcaccaaggagaactacaaccaggagtggtggaacctcaggctgaagtaccagggc
ctctgccccccagtggcccggtctcaaggtgactttgacccaggggccaagttccacgtt
ccttcaagtgtgccttatatcaggtatttcgttggctttgtcattcagttccagttccac
gaggctctgtgtcaggcggctggccacaagggccccttgcacacgtgtgatatctaccaa
tctaaggaggcagggaagcgcctggcggatgccatgaaactgggcttcagtaagccatgg
ccagaagccatgaagctgatcacaggccagtccaacatgtctgcgtccgccatgatgaac
tacttcaagcccttgctggactggctcctcaccgagaacgggaggcacggggagaagctg
ggctggcctcagtacaactggacgccaaactccgctcgctcagaaggccccttcctgggc
accggccgcgtcaacttcctgggcctggacctggaggagcagcaggcccgcgtgggccag
tgggtgctgctcttcctgggcgtcgccctgctggtggccaccttgggcctcacccagcgg
ctcttcagcatccgccaccacagcctccgccggccccaccgtgggccccagtttggctcc
gaggtggagctgagacactcctga

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