Ursus americanus (American black bear): 123803088 Help Entry 123803088         CDS       T07931                                  Symbol SPHK1 Name (RefSeq) sphingosine kinase 1 isoform X1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism uar  Ursus americanus (American black bear) Pathway uar00600   Sphingolipid metabolism uar01100   Metabolic pathways uar04020   Calcium signaling pathway uar04071   Sphingolipid signaling pathway uar04072   Phospholipase D signaling pathway uar04148   Efferocytosis uar04370   VEGF signaling pathway uar04371   Apelin signaling pathway uar04666   Fc gamma R-mediated phagocytosis uar05152   Tuberculosis Module uar_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     123803088 (SPHK1)  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     123803088 (SPHK1)    04071 Sphingolipid signaling pathway     123803088 (SPHK1)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     123803088 (SPHK1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     123803088 (SPHK1)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     123803088 (SPHK1) Enzymes [BR:uar01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      123803088 (SPHK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  123803088 NCBI-ProteinID:  XP_045670239 LinkDB All DBs Position Unknown AA seq 487 aa AA seqDB search MPERAGRRAWSEDLAGRSPPQGAAPDSASSVSSPSDPAAAGDDAGASTAPAPGGEGEPLS RHRDARLGSTDKELKAGATAAGSSATALGTPWQRELRVEVMDPAGGARSLLPRPCRVLVL LNPRGGKGKALQLFRSHVQPLLVQADVSFTLMLTERRNHARELVRVEELGRWDALVVMSG DGLMHEVVNGLMERPDWETAIRKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTL LLCRRLLAPMNLLSLRTASGLRLFSVLSLAWGFIADVDLESEKFRRLGEMRFTLGTFLRL AALRVYQGTLAYLPAERVVSQVPAPPAVERQDQQGPTDAHLVPLEEPVPPHWTVVPEQDF VLVLALLHSHLGSEMFAAPMGRCAAGTMHLFYVRAGVSRAMLLRLFLAMEKGRHMDYDCP YLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPDYVWMVSGCMEPPPSQKPQQG PPPGEPL NT seq 1464 nt NT seq  +upstreamnt  +downstreamnt atgcccgagcgcgcgggtcgccgcgcgtggtccgaggatctagctgggcgctccccacct cagggggccgctccggactccgccagctctgtctcctctccctcagatcccgcagccgca ggggatgacgcgggtgcctccacggccccggctccgggcggggagggcgagcccctcagc cggcaccgcgacgcccgcctgggcagcaccgataaggagctgaaagcaggagccaccgcc gcgggcagctccgcgacagcgctggggacgccctggcagcgggagctgcgagtcgaggtt atggatccagcgggcggcgccaggagcctgctgccccggccctgccgcgtgctggtcctg ttaaacccgcgcggaggcaagggcaaggcgctgcagctcttccgcagccacgtgcagcct ctgctggtccaagccgatgtctccttcacgctcatgctaactgagcggcggaaccatgca cgggagctggtgcgggttgaggagctggggcgctgggatgcgctggtggtcatgtctgga gacgggctgatgcatgaggtggtgaacgggctcatggagcggccagactgggagactgcc atccggaagcccctgtgtagcctcccagctggctctggcaatgcactggcagcttctttg aaccattatgctggctacgagcaggtgactaatgaggacctcctgaccaactgcacgctg ctgctgtgtcgccgcctcctggcgcccatgaacctgctgtcactgaggacagcctcaggg ctgcgcctcttctccgtgctgagcctggcttggggcttcatcgccgacgtggatctggag agtgagaagtttcggcgtctaggggagatgcgcttcactctgggcaccttcctgcgcctg gcagccctgcgagtctaccagggcacgctggcctacctccctgcagaaagggtggtctcc caggtgcccgccccccctgccgtggagcgccaggatcagcagggtcccacggatgcccac cttgtacccctggaggagccggtgcccccgcactggactgtggtcccggagcaggacttc gtgctcgtgctggcgctgctgcactcccacctgggcagcgagatgtttgcggcccccatg ggccgatgtgcggccggcaccatgcatctcttctatgtgcgggcaggcgtgtctcgggcc atgctgctgcgcctcttcctggccatggagaaggggaggcacatggactatgactgtccc tacttggtgtacgtgcctgtggttgccttccgcctggagcccaaggacggaaagggtgtg tttgctgtggatggcgagttgatggtcagcgaggctgtgcagggccaggtgcacccagac tacgtctggatggtcagtggctgcatggagcccccacccagccagaagcctcagcaggga ccacctccaggcgagcccttatga

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