Ursus americanus (American black bear): 123804137 Help Entry 123804137         CDS       T07931                                  Symbol THBS1 Name (RefSeq) thrombospondin-1   KO K16857   thrombospondin 1 Organism uar  Ursus americanus (American black bear) Pathway uar04015   Rap1 signaling pathway uar04115   p53 signaling pathway uar04145   Phagosome uar04148   Efferocytosis uar04151   PI3K-Akt signaling pathway uar04350   TGF-beta signaling pathway uar04510   Focal adhesion uar04512   ECM-receptor interaction uar04820   Cytoskeleton in muscle cells uar05144   Malaria uar05165   Human papillomavirus infection uar05205   Proteoglycans in cancer uar05206   MicroRNAs in cancer uar05219   Bladder cancer Brite KEGG Orthology (KO) [BR:uar00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     123804137 (THBS1)    04350 TGF-beta signaling pathway     123804137 (THBS1)    04151 PI3K-Akt signaling pathway     123804137 (THBS1)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     123804137 (THBS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     123804137 (THBS1)    04148 Efferocytosis     123804137 (THBS1)   09143 Cell growth and death    04115 p53 signaling pathway     123804137 (THBS1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     123804137 (THBS1)   09142 Cell motility    04820 Cytoskeleton in muscle cells     123804137 (THBS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     123804137 (THBS1)    05205 Proteoglycans in cancer     123804137 (THBS1)   09162 Cancer: specific types    05219 Bladder cancer     123804137 (THBS1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     123804137 (THBS1)   09174 Infectious disease: parasitic    05144 Malaria     123804137 (THBS1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:uar04131]     123804137 (THBS1)   09183 Protein families: signaling and cellular processes    00536 Glycosaminoglycan binding proteins [BR:uar00536]     123804137 (THBS1) Membrane trafficking [BR:uar04131]  Endocytosis   Phagocytosis    Opsonins     123804137 (THBS1) Glycosaminoglycan binding proteins [BR:uar00536]  Heparan sulfate / Heparin   Extracellular matrix molecules    123804137 (THBS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TSP_C TSP_3 TSP_1 TSP1_spondin VWC TSP1_CFP_C EGF_3 cEGF EGF_CA TSP1_ADAMTS Laminin_G_3 TSP1_CCN Laminin_G_2 EGF Motif Other DBs NCBI-GeneID:  123804137 NCBI-ProteinID:  XP_045672072 UniProt:  A0A452RRT5 LinkDB All DBs Position Unknown AA seq 1170 aa AA seqDB search MGLAWGLSVLFLLHACGSSRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLAIERKDHSGQVFSVV SNGKAGTLDLSLTVQGMQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD VPIQSIFTRDLASVARLRVAKGGVNDHFQGVLQNVRFVFGTTPEAILRNKGCSSSTNVLL TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK VTEENKELAIELRRPPLCYHNGVQYRNNEEWTVDSCTECRCQNSVTICKKVSCPIMPCSN ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSATCGNGIQQRGRSCDSLNNRCEGSSVQT RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE TKACKKDACPINGGWGPWSLWDLCSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDATEKQI CNKQDCPIDGCLSNPCFAGVKCTSYADGSWKCGACPPGYSGNGVQCEDVDECKEVPDACF NHNGEHRCENTDPGYNCLPCPPRFTGPQPFGRGVDYATANKQVCKPRNPCTDGTHDCNKN AKCSYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNEDLVCVANATYHCKKDNCPN LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN DGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDHDNVPDIDDICPENIDISETDFRRF QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD KTYAGGRLGLFVFSQEMVFFSDLKYECRDS NT seq 3513 nt NT seq  +upstreamnt  +downstreamnt atggggctggcctggggactcagtgtcctattcctgttgcatgcgtgtggttccagccgc attccagagtctgggggagacaacagcgtgttcgacatctttgaactcaccggggctgcc cgtaagggctctgggcgccgactggtgaagggtcctgacccttccagcccagctttccgc atcgaggatgccaacctgattccccctgtgcctgatgacaagttccaagacctagtggat gccgtccgggcagagaaaggcttccttctcttggcctccctgaggcagatgaagaagacc cgaggcactctgctggccatagaacggaaagaccactcgggccaggtcttcagtgtggtc tccaatggcaaagcgggcaccctggacctgagtctcaccgtgcaggggatgcagcatgtg gtgtcggtggaggaggcgctcctggccaccggccagtggaagagcatcaccctgttcgtg caggaggaccgggcgcagctgtacatcgactgtgagaagatggagaacgcagagctggat gtccccatccagagcatcttcaccagggacctggccagcgtggccagactccgcgttgcc aaaggaggggtcaatgaccatttccagggggtgctgcagaacgtgaggtttgtcttcgga accacaccagaagccatcctcaggaacaaaggctgctccagctcaaccaatgtccttctc accctggacaacaatgtggtaaacggctccagccctgccatccgcactaactacattggc cacaagacgaaggatctgcaagccatctgcggcatctcttgtgacgagctgtccagcatg gtcctggagttgaggggcctgcgcaccattgtcaccacactccaggacagcattcgcaaa gtgactgaagagaacaaagagttggccattgagctgaggaggcctccgctctgctaccac aacggagttcagtacaggaataatgaggaatggactgttgatagctgcacggagtgccgc tgtcagaactccgttaccatctgtaagaaagtgtcctgccccatcatgccctgctccaac gccacagtccccgatggagaatgctgcccacggtgttggcccagcgactctgcggatgat ggctggtccccgtggtccgagtggacctcctgctctgcaacctgtggcaatggaatccag cagcgcggtcgctcctgtgacagtctcaacaaccgatgcgagggctcctccgtccagacg cggacctgccacattcaggaatgcgataagagatttaaacaggatggtggctggagccac tggtccccgtggtcatcttgttccgtgacctgcggcgatggtgtgatcacaagaattcga ctctgcaattctccgagcccccagatgaacgggaaaccatgtgaaggcgaagcccgcgag accaaagcctgcaagaaagacgcctgccccatcaacggaggctggggtccctggtcgctg tgggacctctgctctgtcacctgcggaggaggggtgcagaaacgtagccggctgtgcaac aaccccacaccccagtttggaggcaaggactgtgtcggtgacgcgacagaaaaacagatc tgcaacaagcaggactgtccaattgacggatgcctgtccaatccctgctttgctggggtc aagtgtacgagttacgcagatggcagctggaaatgcggtgcctgtcccccgggctacagc ggaaacggcgtccagtgcgaagacgtggatgagtgcaaagaagtacccgacgcctgcttc aaccacaacggcgagcacaggtgtgagaacaccgaccccggctacaactgcctgccctgc ccgcctcgcttcacgggcccgcagcccttcggccggggtgtggactacgccaccgccaac aaacaggtgtgcaagccgcgcaacccctgcacggacgggacgcacgactgcaacaagaac gccaagtgcagctacctgggccactacagcgaccccatgtaccgctgcgagtgcaagccc ggctacgcaggcaacggcatcatctgcggggaggacacagacctggatggatggcccaac gaggacctggtgtgcgtggccaatgccacctaccactgcaaaaaggataactgccccaac ctgccaaactccgggcaggaggactacgacaaggatggaatcggcgacgcctgtgatgac gacgatgacaacgataaaatcccggacgacagggacaactgcccattccattacaaccca gcccagtatgactacgaccgagatgatgtgggagaccgctgtgacaactgcccctacaac cacaaccccgatcaggctgacacggacaacaacggggaaggagacgcctgcgccgcagac atcgatggggacggtatcctcaatgaacgagacaactgccaatatgtctacaacgtggac cagagggacacagatatggatggggttggagatcagtgtgacaactgccccctggaacac aatccagatcagctcgactctgactcagaccgcattggagacacgtgtgacaacaatcag gatattgatgaagatggccaccagaacaacctggacaactgtccctatgtgcccaatgcc aaccaggctgaccatgacaaagatggcaagggagatgcctgtgaccatgatgatgacaat gacggcattcctgatgacagggataactgccgactcgtgcccaaccctgaccagaaggat tctgatggtgatggtcgaggtgatgcctgcaaagacgattttgaccatgacaatgtgcca gacattgatgacatctgtcctgaaaacattgatatcagcgagactgatttccgccgattc cagatgattcctctagatcccaaagggacatcccagaatgaccctaactgggtcgtacgc catcagggtaaagaactcgtccagaccgtcaactgtgatcctggacttgctgtaggttac gatgagtttaatgccgtggacttcagtggcaccttcttcatcaacacagaaagggatgac gactatgctggatttgtgttcggctaccagtctagcagccgcttttatgttgtgatgtgg aagcaagtcacccaatcctactgggacaccaaccccactagggctcagggatactcaggc ctttctgtgaaagttgtgaactcaaccaccgggccaggcgagcacctgcggaatgccctg tggcacacgggaaacacccctggccaggttcgtactctgtggcatgaccctcgtcacata ggctggaaagatttcactgcctacagatggcgtctcagccaccggcccaagacgggtttc attagagtggtgatgtacgaagggaagaaaatcatggctgactcaggacccatctatgac aaaacctatgctggtggtaggctagggttgtttgtcttctcgcaagaaatggtgttcttc tccgacctgaaatacgaatgcagagattcctaa

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