Ursus maritimus (polar bear): 103656869 Help Entry 103656869         CDS       T03271                                  Symbol MDM2 Name (RefSeq) E3 ubiquitin-protein ligase Mdm2   KO K06643   E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] Organism umr  Ursus maritimus (polar bear) Pathway umr01522   Endocrine resistance umr01524   Platinum drug resistance umr04068   FoxO signaling pathway umr04110   Cell cycle umr04115   p53 signaling pathway umr04120   Ubiquitin mediated proteolysis umr04144   Endocytosis umr04151   PI3K-Akt signaling pathway umr04218   Cellular senescence umr04625   C-type lectin receptor signaling pathway umr04919   Thyroid hormone signaling pathway umr05163   Human cytomegalovirus infection umr05165   Human papillomavirus infection umr05169   Epstein-Barr virus infection umr05200   Pathways in cancer umr05202   Transcriptional misregulation in cancer umr05203   Viral carcinogenesis umr05205   Proteoglycans in cancer umr05206   MicroRNAs in cancer umr05214   Glioma umr05215   Prostate cancer umr05218   Melanoma umr05219   Bladder cancer umr05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:umr00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     103656869 (MDM2)  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     103656869 (MDM2)    04151 PI3K-Akt signaling pathway     103656869 (MDM2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     103656869 (MDM2)   09143 Cell growth and death    04110 Cell cycle     103656869 (MDM2)    04115 p53 signaling pathway     103656869 (MDM2)    04218 Cellular senescence     103656869 (MDM2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     103656869 (MDM2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     103656869 (MDM2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103656869 (MDM2)    05202 Transcriptional misregulation in cancer     103656869 (MDM2)    05206 MicroRNAs in cancer     103656869 (MDM2)    05205 Proteoglycans in cancer     103656869 (MDM2)    05203 Viral carcinogenesis     103656869 (MDM2)   09162 Cancer: specific types    05214 Glioma     103656869 (MDM2)    05220 Chronic myeloid leukemia     103656869 (MDM2)    05218 Melanoma     103656869 (MDM2)    05219 Bladder cancer     103656869 (MDM2)    05215 Prostate cancer     103656869 (MDM2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     103656869 (MDM2)    05169 Epstein-Barr virus infection     103656869 (MDM2)    05165 Human papillomavirus infection     103656869 (MDM2)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     103656869 (MDM2)    01522 Endocrine resistance     103656869 (MDM2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:umr04131]     103656869 (MDM2)    04121 Ubiquitin system [BR:umr04121]     103656869 (MDM2) Enzymes [BR:umr01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      103656869 (MDM2) Membrane trafficking [BR:umr04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     103656869 (MDM2) Ubiquitin system [BR:umr04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    MDM2/MDM4 proteins     103656869 (MDM2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  zf-C3HC4_3 Zn_ribbon_RanBP SWIB zf-RING_2 zf-FPG_IleRS Motif Other DBs NCBI-GeneID:  103656869 NCBI-ProteinID:  XP_008682493 UniProt:  A0A384BIS0 LinkDB All DBs Position Unknown AA seq 487 aa AA seqDB search MCNTNMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQHEPSDSGT SVSENRCHLEGGSDQKEPAQELQEEKPSSSDLVSRPSTSSRRRAISETEEHSDELPGERQ RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDS VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLA DYWKCTSCNEMNPPLPPHCNRCWALRENWLPEDKGKIPEKAKLENSTQVEEGFDVPDCKK TAVNDSRESCAEENDDKITQASQSQESEDYSQPSTSNSIIYSSQEDVKEFEREETQDKEE VVESSFPLNAIEPCVICQGRPKNGCIVHGRTGHLMACFTCAKKLKKRNKPCPVCRQPIQM IVLTYFP NT seq 1464 nt NT seq  +upstreamnt  +downstreamnt atgtgcaataccaacatgtctgtgtctactgatggtgctgtaagcacctcacagattcca gcttcggaacaggagaccctggttagaccaaagcctttgcttttgaagttgttaaagtct gttggtgcacaaaaagacacttatactatgaaagaggttatattttatcttggccagtat attatgactaaacgattatatgatgagaagcaacagcatattgtgtattgttccaatgat cttctaggggatttgtttggagtgccaagcttctctgtgaaagagcacaggaaaatatat acaatgatctacagaaacttggtagtagtcaatcagcatgaaccatcagattcaggcaca tctgtgagtgaaaataggtgtcaccttgaaggtgggagtgatcaaaaggagccggcgcaa gagttgcaggaagagaaaccttcatcttcagatttggtttctagaccgtctacctcatct agaaggagagcaattagtgagacagaagaacattcagatgaattacctggtgaacggcag agaaagcgccacaaatctgatagtatttccctgtcctttgatgaaagccttgctctgtgt gtaataagggagatatgctgtgaaagaagcagtagcagtgaatcaacagggacaccatca aatccggatcttgatgctggtgtaagtgagcattcaggtgactggttggatcaggattca gtttcagatcaattcagtgtagaatttgaagttgagtctctcgattcagaagattacagt cttagtgaagaagggcaagaactctcagatgaagatgatgaggtatatcgagtaactgtg tatcaggcaggggagagtgataccgattcatttgaagaagatcctgaaatttccttagct gactattggaagtgtacttcgtgcaatgaaatgaatcctcctcttccacctcattgcaac agatgttgggcccttcgtgagaactggcttcctgaagataaagggaaaatacctgagaaa gccaaactagaaaactcaacacaagtagaagagggctttgatgtccctgattgtaaaaaa actgcagtgaatgattccagagaatcatgtgctgaggaaaatgatgataaaatcacacaa gcctcccaatcccaagaaagtgaggattattctcagccatcaacttctaacagcatcatt tacagcagccaagaagatgtcaaagagtttgagagggaggaaacacaagacaaagaagag gttgtggaatctagttttcccctgaatgccattgaaccttgtgtgatttgccagggtcga cctaaaaacggttgcattgttcatggcagaacaggacatcttatggcgtgctttacgtgt gcaaagaagctcaagaaaaggaataagccctgcccagtatgtagacagccaattcaaatg attgtgctaacttatttcccctag

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