KEGG   Ursus maritimus (polar bear): 103658031
Entry
103658031         CDS       T03271                                 
Name
(RefSeq) toll-like receptor 2
  KO
K10159  toll-like receptor 2
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04145  Phagosome
umr04151  PI3K-Akt signaling pathway
umr04613  Neutrophil extracellular trap formation
umr04620  Toll-like receptor signaling pathway
umr05132  Salmonella infection
umr05134  Legionellosis
umr05140  Leishmaniasis
umr05142  Chagas disease
umr05144  Malaria
umr05145  Toxoplasmosis
umr05146  Amoebiasis
umr05152  Tuberculosis
umr05161  Hepatitis B
umr05162  Measles
umr05168  Herpes simplex virus 1 infection
umr05169  Epstein-Barr virus infection
umr05170  Human immunodeficiency virus 1 infection
umr05171  Coronavirus disease - COVID-19
umr05205  Proteoglycans in cancer
umr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
umr05321  Inflammatory bowel disease
umr05323  Rheumatoid arthritis
umr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    103658031
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    103658031
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    103658031
   04620 Toll-like receptor signaling pathway
    103658031
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103658031
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103658031
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103658031
   05161 Hepatitis B
    103658031
   05171 Coronavirus disease - COVID-19
    103658031
   05162 Measles
    103658031
   05168 Herpes simplex virus 1 infection
    103658031
   05169 Epstein-Barr virus infection
    103658031
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103658031
   05134 Legionellosis
    103658031
   05152 Tuberculosis
    103658031
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103658031
   05144 Malaria
    103658031
   05145 Toxoplasmosis
    103658031
   05140 Leishmaniasis
    103658031
   05142 Chagas disease
    103658031
  09163 Immune disease
   05323 Rheumatoid arthritis
    103658031
   05321 Inflammatory bowel disease
    103658031
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103658031
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:umr04131]
    103658031
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:umr04147]
    103658031
   04054 Pattern recognition receptors [BR:umr04054]
    103658031
   04090 CD molecules [BR:umr04090]
    103658031
   00536 Glycosaminoglycan binding proteins [BR:umr00536]
    103658031
Membrane trafficking [BR:umr04131]
 Endocytosis
  Phagocytosis
   Toll-like receptors
    103658031
Exosome [BR:umr04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   103658031
Pattern recognition receptors [BR:umr04054]
 Membrane-bound pattern recognition receptors
  Toll-like receptors
   103658031
CD molecules [BR:umr04090]
 Proteins
  103658031
Glycosaminoglycan binding proteins [BR:umr00536]
 Hyaluronan
  Cell surface receptors
   103658031
SSDB
Motif
Pfam: LRR_8 LRR_4 TIR TIR_2 LRR_1 LRR_5 LRR_13 LRR_9 LRR_LRWD1 LRR_Zer-1 LRRCT
Other DBs
NCBI-GeneID: 103658031
NCBI-ProteinID: XP_040482309
UniProt: A0A8M1FPB6
LinkDB
Position
Unknown
AA seq 785 aa
MSRVLWTVWVLGAVTNLSKEEASDQAASLSCDPTGVCDGRSRSLNSMPSGLTAAVRSLDL
SNNEITYLGNGDLRGCVNLEALNLGSNGINTIEEDSFFSLRRLEHLDLSYNLLSNLSSSW
FRPLSSLKFLNLLGNLYKSLGETPLFSQLMNLRILKVGNIYSFTELQEKDFAGLTFLEEL
EIDASNLQRYEPKTLKSIQNISHLALRMKQPVFLLEIFADLSSSLKHLELRDTHLNTFRF
SKASISETNTLITKWTFRKVKITDGSFSEVVKLLNYVSGVLEVEFEDCTLDGLGDFNIAD
MDKIKNIGGIETLTVRRLYIPYFYSFYDMSSIYSLTEDVKRVTVESSKVFLVPCSLSQHL
KSLEYLDLSDNLMVEEYLGNSACEHAWPLLQTLTLRQNRLKSLEKTGETLLTLKNLMNLD
ISKNNFVSMPETCQWPEKLKYLNLSNTRINSVTRCIPWTLEILDISNNVLESFSLVLPQL
KELYISRNKLKTLPDASFLPMLRVMRISRNTISTFSKAQLDSFHTLKALEAGGNNFLCSC
EFLSFTQGQQALAQILTDWPENYLCDSPFYVRGQRVRDTRLPVSECHRAALVSAVCSVLF
LLIVLTGVLCHRFHGLWYLKMMWAWLQAKRKPRKAPAGDVCYDAFVSYSERDSYWVENLM
VQELEHFNPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTIFVLSENFVKSEWCKYELDF
SHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPTDETQQEGFWLNLR
TAIRS
NT seq 2358 nt   +upstreamnt  +downstreamnt
atgtcacgtgttttgtggacagtatgggtgttgggggctgtaaccaacctctccaaagaa
gaggcctctgatcaggctgcttctctgtcctgtgaccccactggtgtctgcgatggccgc
tccagatctttaaactccatgccctcagggctcacggcagctgtgaggagccttgacctc
tccaacaacgagatcacctaccttggcaacggtgacctgcggggctgtgtgaacctcgag
gctttgaacctggggtctaatggaattaacacaatagaggaagattcttttttttccctg
cggcgtcttgaacatttggacttatcctataatctcttatctaacttatcatcctcctgg
ttcaggcccctttcttccctgaagttcttaaacttactgggaaatctttacaaatcactc
ggggaaacacctcttttttctcagctcatgaatttgcgaattctgaaagtaggaaatatt
tacagcttcactgagcttcaggaaaaggattttgctgggctcacttttctcgaggaactt
gagattgatgcttccaatctccagaggtatgagccaaagactttgaagtcaattcagaac
atcagtcacctggctcttcgtatgaagcagcctgttttcctgctggagatttttgcagat
ctttcaagttccttgaaacatttagaactgagagatactcatttgaacactttccgtttt
tcaaaagcatccatcagtgaaacaaatacgttgattacaaagtggacgtttagaaaagtg
aaaatcaccgatggaagttttagcgaagttgtgaaactgctgaattatgtttctggagtg
ttagaagtcgagtttgaggactgtaccctggatgggctgggtgattttaacatagccgat
atggacaaaattaaaaatataggtgggatagagacattaacagtacggaggttgtatatt
ccatacttttactcattttatgatatgagtagtatctattcacttacggaagacgttaaa
cgagtcacagtagaaagcagtaaggttttcctggttccttgctcactttcacaacattta
aaatcactagaatatttggatctcagtgacaatttaatggttgaagaatacttgggaaac
tcagcctgtgagcacgcctggcccctcctgcaaaccttaactttaaggcaaaaccgtttg
aaatcattagaaaaaaccggagaaacgttgcttactctgaaaaacctgatgaaccttgat
attagtaagaataattttgtttctatgcctgaaacttgtcagtggccagagaagttgaaa
tacttgaacttatccaacacgagaataaatagtgtaacccgttgcatcccctggacactg
gaaattttagatattagcaataacgttctcgagtcattttccctggttttgccacaactc
aaagaactttacatttccagaaataagttgaagactctaccggatgcctccttcttaccc
atgttacgagtcatgagaattagcagaaatacaataagtactttctctaaggcgcagctg
gattcttttcacacactgaaggccttggaagccggcggtaacaatttcctttgctcttgt
gaattcctgtctttcactcaagggcagcaagcgctggcccagatcctgaccgactggcca
gagaactacctgtgtgactctccattctacgtgcgcggccagcgggttcgggacacgcgt
ctcccggtctctgaatgccaccgggcagctctggtgtccgccgtgtgctctgtcctcttc
ctgctgattgtgctcacaggggtcctgtgccaccgcttccacgggctgtggtacctgaaa
atgatgtgggcctggctccaggccaagaggaagcccaggaaagcccccgccggggacgtc
tgctatgatgcctttgtgtcctacagtgagcgcgattcctactgggtggagaacctgatg
gtccaggagctggagcacttcaaccctcccttcaagctgtgtctgcataagcgggacttt
gttcccggcaaatggatcattgacaacatcatcgactccatcgagaagagccacaagacc
atctttgtgctgtcggaaaactttgtgaagagtgagtggtgcaagtatgagctggacttc
tcccattttcgcctctttgatgagaacaatgatgccgccattctcattcttctggaaccc
attgagaaaaaggcaattccccagcgtttctgtaagctgaggaagataatgaacaccaag
acctacctggagtggcccaccgatgaaactcagcaggaagggttttggttaaatttgaga
acagcaataaggtcctag

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