Ursus maritimus (polar bear): 103658871 Help Entry 103658871         CDS       T03271                                  Symbol IL6 Name (RefSeq) interleukin-6   KO K05405   interleukin 6 Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr01523   Antifolate resistance umr04060   Cytokine-cytokine receptor interaction umr04061   Viral protein interaction with cytokine and cytokine receptor umr04066   HIF-1 signaling pathway umr04068   FoxO signaling pathway umr04151   PI3K-Akt signaling pathway umr04218   Cellular senescence umr04620   Toll-like receptor signaling pathway umr04621   NOD-like receptor signaling pathway umr04623   Cytosolic DNA-sensing pathway umr04625   C-type lectin receptor signaling pathway umr04630   JAK-STAT signaling pathway umr04640   Hematopoietic cell lineage umr04657   IL-17 signaling pathway umr04659   Th17 cell differentiation umr04668   TNF signaling pathway umr04672   Intestinal immune network for IgA production umr04931   Insulin resistance umr04932   Non-alcoholic fatty liver disease umr04933   AGE-RAGE signaling pathway in diabetic complications umr04936   Alcoholic liver disease umr05010   Alzheimer disease umr05020   Prion disease umr05022   Pathways of neurodegeneration - multiple diseases umr05132   Salmonella infection umr05133   Pertussis umr05134   Legionellosis umr05135   Yersinia infection umr05142   Chagas disease umr05143   African trypanosomiasis umr05144   Malaria umr05146   Amoebiasis umr05152   Tuberculosis umr05161   Hepatitis B umr05162   Measles umr05163   Human cytomegalovirus infection umr05164   Influenza A umr05166   Human T-cell leukemia virus 1 infection umr05167   Kaposi sarcoma-associated herpesvirus infection umr05168   Herpes simplex virus 1 infection umr05169   Epstein-Barr virus infection umr05171   Coronavirus disease - COVID-19 umr05200   Pathways in cancer umr05202   Transcriptional misregulation in cancer umr05321   Inflammatory bowel disease umr05323   Rheumatoid arthritis umr05332   Graft-versus-host disease umr05410   Hypertrophic cardiomyopathy umr05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     103658871 (IL6)    04668 TNF signaling pathway     103658871 (IL6)    04066 HIF-1 signaling pathway     103658871 (IL6)    04068 FoxO signaling pathway     103658871 (IL6)    04151 PI3K-Akt signaling pathway     103658871 (IL6)   09133 Signaling molecules and interaction    04061 Viral protein interaction with cytokine and cytokine receptor     103658871 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     103658871 (IL6)    04620 Toll-like receptor signaling pathway     103658871 (IL6)    04659 Th17 cell differentiation     103658871 (IL6)    04657 IL-17 signaling pathway     103658871 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103658871 (IL6)    05202 Transcriptional misregulation in cancer     103658871 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103658871 (IL6)    05161 Hepatitis B     103658871 (IL6)    05171 Coronavirus disease - COVID-19     103658871 (IL6)    05164 Influenza A     103658871 (IL6)    05162 Measles     103658871 (IL6)    05163 Human cytomegalovirus infection     103658871 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     103658871 (IL6)    05169 Epstein-Barr virus infection     103658871 (IL6)   09171 Infectious disease: bacterial    05135 Yersinia infection     103658871 (IL6)    05133 Pertussis     103658871 (IL6)    05134 Legionellosis     103658871 (IL6)    05152 Tuberculosis     103658871 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     103658871 (IL6)    05144 Malaria     103658871 (IL6)    05142 Chagas disease     103658871 (IL6)    05143 African trypanosomiasis     103658871 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     103658871 (IL6)    05321 Inflammatory bowel disease     103658871 (IL6)    05332 Graft-versus-host disease     103658871 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     103658871 (IL6)    05020 Prion disease     103658871 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     103658871 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     103658871 (IL6)    05410 Hypertrophic cardiomyopathy     103658871 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     103658871 (IL6)    04932 Non-alcoholic fatty liver disease     103658871 (IL6)    04931 Insulin resistance     103658871 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     103658871 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103658871 (IL6)    01523 Antifolate resistance     103658871 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:umr04052]     103658871 (IL6) Cytokines and neuropeptides [BR:umr04052]  Cytokines   Interleukins    103658871 (IL6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL6 GCSF IL11 IL23 Motif Other DBs NCBI-GeneID:  103658871 NCBI-ProteinID:  XP_008684599 UniProt:  A0A384BQQ8 LinkDB All DBs Position Unknown AA seq 211 aa AA seqDB search MNSLSTSAFSPVAFSLGLLLVMATAFPTPGHLGRDPKDEATSNRPPLISADKMEIIKYIL GRISALKKEMCDKYNKCEDSKEALAENNLHLPKLAEKDGCFQSGFNQDTCLTRIATGLLE FQVHLKYLQANYEGDKENANSVYFSTKVLLQMLMEKVKNQDEVTTPDPTTDTGLQAILKS QDKWLKQTTIHLILQNFEDFLQFSLRAVRVM NT seq 636 nt NT seq  +upstreamnt  +downstreamnt atgaactccctctccacaagcgccttcagtccagttgccttctccctggggctgctcctg gtgatggctactgctttccctaccccgggacacctgggaagagatcccaaagatgaggcc acctcaaatagaccaccactcatctctgcagacaaaatggaaatcattaaatacatcctc ggcagaatctctgcactgaaaaaggagatgtgtgacaagtataacaagtgtgaagacagc aaggaggcactggcagaaaacaacttacatcttccaaaactggcagaaaaggacggatgc ttccaatctgggttcaatcaggacacctgcctgacaagaatcgctaccggtcttctggag tttcaggtacacctgaaatacctccaggccaactatgaaggtgataaggaaaatgccaac tctgtgtacttcagtaccaaagtcctgctccagatgctgatggaaaaggtaaagaatcag gatgaagtgaccaccccagaccccaccacagacaccggcctgcaggctatcctgaagtcg caggacaagtggctgaagcaaacaacaattcacctcatcctgcagaactttgaggatttc ctgcagttcagcctgagggcagtgcgggtcatgtag

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