Ursus maritimus (polar bear): 103662006 Help Entry 103662006         CDS       T03271                                  Symbol MTR Name (RefSeq) methionine synthase isoform X1   KO K00548   5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] Organism umr  Ursus maritimus (polar bear) Pathway umr00270   Cysteine and methionine metabolism umr00450   Selenocompound metabolism umr00670   One carbon pool by folate umr01100   Metabolic pathways umr01230   Biosynthesis of amino acids umr01523   Antifolate resistance umr04980   Cobalamin transport and metabolism umr04981   Folate transport and metabolism Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09105 Amino acid metabolism    00270 Cysteine and methionine metabolism     103662006 (MTR)   09106 Metabolism of other amino acids    00450 Selenocompound metabolism     103662006 (MTR)   09108 Metabolism of cofactors and vitamins    00670 One carbon pool by folate     103662006 (MTR)  09150 Organismal Systems   09154 Digestive system    04981 Folate transport and metabolism     103662006 (MTR)    04980 Cobalamin transport and metabolism     103662006 (MTR)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     103662006 (MTR) Enzymes [BR:umr01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.13  methionine synthase      103662006 (MTR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD Motif Other DBs NCBI-GeneID:  103662006 NCBI-ProteinID:  XP_040479733 UniProt:  A0A8M1F8H8 LinkDB All DBs Position Unknown AA seq 1266 aa AA seqDB search MSPALPELTPSAGVKKSLQDEIEAILRERIMVLDGGMGTMIQRHKLSEEDFRGHEFQDHA RLLKGNNDILSITQPSVIYQIHKDYLLAGADIIETNTFSSTNIAQADYGLEHLAYQMNKC SAGLARKAAEEVSLQTGIKRFVAGALGPTNKTLSVSPSVEKPDYRNITFDELVEAYKEQA KGLLDGGVDILLIETIFDTANAKAALFALQTLFEEEYSPRPIFISGTIIDKSGRTLSGQM GEAFVISVSHADPLCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDET PHMMATQLKDFAMDGLVNIVGGCCGTTPDHIREIAKAVRNCKPRVPPATVFEEHMLLSGL EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALSVAKVQVEMGAQVLDINMDDG MLDGSSAMTRFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEED FLAKARKIKKFGAAVVVMAFDEEGQATETDTKISVCMRAYHLLVKKLGFNPNDIIFDPNI LTIGTGMEEHNLYAVNFIRATKIIKETLPGARVSGGLSNLSFSFRGMEAIREAMHGVFLY HAIKFGMDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTHGKGGKKV IQTDEWRNGPIEERLEYALVKGIEKYIIEDTEEARLNQEKYPRPLNIIEGPLMNGMKVVG DLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREENKMHAGTEEEEDPYQGTIVLATV KGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEM IFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDEN LKDEFFEEILEEYEDIRQDHYESLKERRYLTLSQARKNGFHIDWLSEPPPVKPTFLGTRV FKDYDLRKLVAYIDWKPFFDVWQLRGKYPNRSFPKIFKDKTVGEEAKKVYDDAQNMLEVL ISQKKLRARGVVGFWPAQSVEDDIHLYAEGATPQAAEPIATFHGLRQQAEKDSASTDPYH CLSDFIAPLHSGVRDYLGLFAVACFGVEELSKAYEQECDDYSSIMVKALGDRLAEAFAEE LHERVRRELWAYCSCEQLDVADLRRLRYKGIRPAPGYPSQPDHSEKLTMWKLADVERCTG IRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQIEDYAVRKNMSVAEVEKWLGPVL GYDTES NT seq 3801 nt NT seq  +upstreamnt  +downstreamnt atgtcgcccgcactgccagagctgacgccttccgcaggtgtgaagaaaagcctgcaggat gagattgaagccattctacgggagaggatcatggtgctggatggagggatggggaccatg atccagaggcataagctaagtgaagaagacttccgaggtcacgaatttcaagatcacgcc aggctgctgaaaggcaacaatgacattttaagcataactcaacccagtgttatttaccaa atccataaggattacttgctggctggggcagatatcatcgaaacaaacactttcagcagc actaacattgcccaagcagactatggcctcgaacacttggcctaccagatgaacaaatgc tccgcgggactggccagaaaggcagccgaggaggtgtccctccagacaggaattaagagg tttgtggcaggagctctgggtccaactaataagacactgtcagtgtctccgtcggtggag aaaccagattacaggaacattacatttgatgaactcgttgaagcatacaaagagcaggcc aaagggcttctggatggtggggttgatatcttactcattgaaactatttttgataccgcc aatgccaaggcagccttgttcgcactccagacactttttgaagaggagtattccccccgg cctatcttcatttcagggacaattattgataaaagtgggcgaactctttccggacagatg ggagaggcatttgtcatcagtgtgtctcacgcagaccccctctgcattggattaaactgt gctctgggtgcagctgaaatgagaccttttattgaaacaattggaaaatgtacaacagcc tatgtcctctgttatcccaatgcaggtcttcccaacacgtttggtgactacgacgagact ccgcatatgatggccacgcaactaaaggactttgctatggatggcttggtcaatatagtg ggtggctgctgtggtacgacacctgatcacatcagggagattgctaaagctgtgagaaac tgtaagcctagagttccacctgccactgtttttgaagagcatatgttactatctggtcta gagcccttcaggatcggaccgtacaccaactttgttaacattggagagcgctgtaacgtg gcaggatccaggaagtttgctaaactcatcatggcaggaaactatgaagaagcgctgagt gttgccaaagtgcaggtggaaatgggagcgcaggtgttggatatcaacatggatgacggc atgctggacggttccagtgcaatgaccagattttgcaacttcattgcttccgagcccgac atcgccaaggtgcccttgtgcatcgactcttccaattttgctgtgattgaagccggcttg aagtgctgccagggcaagtgcattgtcaacagcattagcctgaaggagggagaggaagac ttcttggcgaaggctagaaagattaagaagtttggagctgctgtggtggtcatggctttt gatgaagaaggacaggcgacagaaacagacaccaaaatcagcgtgtgcatgcgggcctac catctacttgtgaaaaaactgggctttaatccaaatgacatcatctttgacccaaacatc ctcaccattggtactgggatggaagagcacaacttgtatgctgttaattttatccgtgca acaaaaatcattaaagaaaccctacctggagcccgagtaagtggaggtctttccaacttg tccttctccttccgaggaatggaagccattcgagaagcaatgcatggagttttcctttac cacgcaatcaagtttggtatggacatggggatagtgaatgccggaaacctccctgtatat gacgatatccacaaggagcttctccagctctgtgaagatctcatctggaataaagaccct gaggccactgagaagctcctgcgctatgctcagacacatggcaaaggagggaagaaagtc atccagactgacgagtggaggaatggccccattgaagaacgcctggagtacgccctcgtg aagggtatcgaaaaatatattattgaggacactgaagaagccaggttaaaccaggaaaag tatccccggcctctgaatataatcgaagggcctctgatgaacggcatgaaagttgtcggt gacctctttggagctggaaaaatgtttctacctcaggttataaagtcagctcgagtcatg aagaaggctgttggccaccttattcccttcatggagaaagaaagagaagagaacaaaatg catgctggcacagaagaagaagaggacccctaccagggcaccattgtgttggctaccgtg aagggcgacgtgcacgacataggcaagaacatagttggcgtggtccttggctgcaataat ttcagagttattgatttaggggtcatgactccctgtgacaagatcctgaaagctgctctt gaccacaaagcagatataattggcctatcaggactcatcactccttccctggatgaaatg atttttgttgccaaggaaatggagagattggctataaagattccactgttgattggagga gcaaccacatccagaacccacacggcagtgaaaatagctccaagatacagcgcacctgtc atccacgtcctggacgcatccaagagtgtggtggtgtgctcgcaactgttagatgagaat ctaaaggatgaattttttgaggagatcctggaagaatatgaagatattagacaggaccat tacgagtctctcaaggagagaagatacttaaccttaagtcaagctagaaaaaatggtttc catattgactggctgtcagagccccctccagtgaagcccacgtttcttgggactcgggtc ttcaaagactatgacctgcggaagctggtggcctacatcgactggaaacccttctttgat gtctggcagctccggggcaagtacccgaatcgaagctttcccaagatatttaaggacaaa actgtaggtgaagaggccaaaaaagtctatgacgatgcccaaaacatgctggaagtgctg atcagtcagaagaagctccgagccaggggcgtggtggggttctggccggcgcagagcgtg gaagacgacatccacctgtacgcggagggcgccacgccgcaggccgcagagcccatagct accttccacgggctgaggcagcaggccgagaaggactctgccagcacggacccataccac tgcctctcggacttcatcgctccgctgcattccggcgtccgcgactacctgggcctgttt gccgtcgcctgcttcggggtggaggagctgagcaaggcctacgagcaggagtgtgacgac tacagcagcatcatggtcaaggctctgggagaccggctggctgaggcctttgcggaggag ctccacgagcgggtccgccgggagctgtgggcctattgcagctgcgagcagctggatgtt gccgacctgcggcggctccgatacaagggcatccggccggctcccggctaccccagccag cctgaccacagcgagaagctcaccatgtggaagctcgccgatgtggagcggtgcacgggc attaggttaacggagtccttagcaatggcacctgcttcggcggtatccggcctctacttc tccaatttgaagtcgaaatactttgcagtggggaaaatttccaaggatcagattgaggac tatgctgtgcggaagaacatgtccgtggccgaggttgagaaatggctgggacccgttttg ggatacgacacagaaagttaa

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