Ursus maritimus (polar bear): 103664410
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Entry
103664410 CDS
T03271
Symbol
FLT1
Name
(RefSeq) vascular endothelial growth factor receptor 1
KO
K05096
FMS-like tyrosine kinase 1 [EC:
2.7.10.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04010
MAPK signaling pathway
umr04014
Ras signaling pathway
umr04015
Rap1 signaling pathway
umr04020
Calcium signaling pathway
umr04066
HIF-1 signaling pathway
umr04151
PI3K-Akt signaling pathway
umr04510
Focal adhesion
umr05202
Transcriptional misregulation in cancer
umr05323
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103664410 (FLT1)
04014 Ras signaling pathway
103664410 (FLT1)
04015 Rap1 signaling pathway
103664410 (FLT1)
04066 HIF-1 signaling pathway
103664410 (FLT1)
04020 Calcium signaling pathway
103664410 (FLT1)
04151 PI3K-Akt signaling pathway
103664410 (FLT1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103664410 (FLT1)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
103664410 (FLT1)
09163 Immune disease
05323 Rheumatoid arthritis
103664410 (FLT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103664410 (FLT1)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103664410 (FLT1)
Protein kinases [BR:
umr01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
103664410 (FLT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_3
I-set
Pkinase
ig
VEGFR-1-like_Ig-like
Ig_2
Ig_VEGFR-1-like_5th
V-set
VEGFR-2_TMD
VEGFR1-3_N_Ig-like
Ig_4
C1-set
Ig_5
Herpes_gE
Haspin_kinase
Glu2-Pro
Motif
Other DBs
NCBI-GeneID:
103664410
NCBI-ProteinID:
XP_040477793
UniProt:
A0A8M1F2X7
LinkDB
All DBs
Position
Unknown
AA seq
1337 aa
AA seq
DB search
MVSCWDTGVLLCALLGGLLLTGSSSGSKLKGPELSLKGTQHVMQAGQTLYLKCRGEAAHS
WSLPETVRKESKRLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLSIPASKKKKT
ESTIYIFINDTGRPFLEMHSEIPEIIYMTEGREIVIPCRVTSPNITVTLKKFPLDTLIPD
GKRIIWDSRKGFIIANATYREIGLLTCETAVNGHLYKTNYLTYRQTNTIQDVQISTPSPV
KLLRGHTLTLNCTATTDLNTRVQMTWSYPGETKKRASIRQRIGQRTSIAIVFYSVLVIDK
VQNKDKGLYTCHVKSGPSFRSVNTSVHIYDKAFITAKHRKQHVLETIAGKRSYRLSVKVK
AFPSPELLWLKDGFPVTEKSPRYLVHGYSLIIKDVAEEDAGDYTILLAIKQSSVFKNLTT
TLIVNVKPQIYEKAVSSFPDPTLYLLGSRQTLTCTVYGIPQPTVTWFWRPCNHSHSKARY
DFCSNKEESLILDPDSNIGNRIESITQRMAIIEGKNKTASTLVVADSRISGIYSCMASNK
VGTVGRNISFYITDVPNGFHVNLEKMPTEGEDLKLSCTVNKFLYRDITWILLRTVKNRTM
HHSISKQKMAITKEYSVTLNVTIKNVSLEDSGTYACRARNIYTGEEILQKKEVTIRDQEA
PRLLRNLSDHAVAISSSTTLDCRATGVPEPRITWFKNHRKIQQEPGIILGPGSSTLFIER
VTEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFI
RKLKRSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGKV
VQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTKQ
GGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHVEPKKEKMEPDLEQDKKQRLDSVT
SSESFASSGFQEDKSLSDVEEEEDSDDFYKQPITMEDLISYSFQVARGMEFLSSRKCIHR
DLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSD
VWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRAPEYATPEIYQIMLDCWHKDP
KERPRFAELVEKLGDLLQANVQQDGKDYIPLNAVLTGNSAFTYSSPAFSDDFFKEDISAP
KFNSGSSDNVRYVNAFNFMSLERIKTFGELSPNTTSIFDDYQVDSSTLLASPWLKRFTWA
ESKPKASVKIDLRVTSKSKESGLSELTQPAFCHAGCAHVNRGRRRFTYDNSELEKKISCC
SPPPDYNSVVLYSTPPV
NT seq
4014 nt
NT seq
+upstream
nt +downstream
nt
atggtcagctgctgggacaccggggtcctgctgtgcgcgctgcttggaggtttgctgctt
acaggatctagttcaggttcaaaattaaaaggtcctgaactgagtttaaaaggcacccag
cacgtcatgcaagcaggccagacactgtatctcaaatgtagaggggaagcagcccattca
tggtctttgcctgaaacagtgagaaaggaaagcaaaaggctgagcatcactaaatctgcc
tgtggaaggaatggcaaacagttctgcagtactttgaccttgaacacggctcaggcaaac
cacactggcttctatagctgcaaatatctatctatacctgcttcaaagaagaagaaaaca
gaatctacaatctatatatttattaatgatacaggtagacctttcttagagatgcacagt
gaaatacccgaaattatatatatgactgaaggaagggagatcgtcatcccctgccgggtc
acgtcacctaacatcactgtgactttaaaaaagtttccccttgataccctgatcccggat
ggaaagcgaataatctgggacagtaggaagggttttataatagcaaatgcaacatacaga
gaaatagggcttctgacctgtgaaacagcagtcaatggacatctgtacaagaccaactat
ctcacctatcgacaaaccaataccatccaagatgtccagataagcactccaagcccggtc
aagttgcttcgaggtcacactcttactctgaactgcactgccaccactgatttgaacaca
agggttcaaatgacctggagttaccccggggaaacaaagaagagagcatctataaggcaa
cgaattggccagcgcacttccattgccattgtgttctacagcgttcttgttattgacaaa
gtacagaacaaagacaaagggctttacacttgccatgtgaagagcggcccttcattcaga
tctgttaacacctcagtgcatatatatgataaagcattcatcaccgccaagcatcgaaag
cagcacgtgctggagaccatagctggcaagcggtcctacaggctctctgtgaaagtgaag
gcatttccctcgccagagcttctatggttaaaagatgggttccctgtgactgagaaatct
cctcgctatttggttcatggctactcgttaattatcaaagatgtcgctgaagaagatgcc
ggggattacacgatcttgctggctataaagcagtccagtgtgtttaaaaaccttaccacc
actttaattgtaaatgtgaaaccccagatctatgaaaaggccgtgtcatcctttccagac
ccgactctctatctcctgggcagcagacagaccctgacttgtaccgtttatggtatccct
caacctacagtcacgtggttctggcgtccctgtaaccatagtcattccaaagcaaggtat
gacttttgctccaataaggaagagtccctaatcctggatcctgacagcaacataggaaac
aggattgaaagcatcactcagcgcatggcaataatagaaggaaagaataagacggctagc
accttggttgtggctgactctagaatttctggaatctacagttgcatggcttccaataaa
gtagggactgtgggaagaaacataagcttttatatcacagatgtgccaaatggatttcat
gttaacttggaaaaaatgcccacagaaggagaggacctgaaactgtcttgcacagttaac
aagttcttatacagagacattacttggattttgctgcggacagttaaaaaccgaacaatg
catcacagcatcagcaagcaaaaaatggccatcactaaagagtactccgtcaccctcaat
gtcaccatcaagaacgtttccctggaagattcaggcacgtacgcctgcagagccaggaac
atatacacaggggaagaaatccttcagaagaaagaagttacaattagagatcaggaagcg
ccacgcctcctgcgcaacctcagtgaccacgccgtggccatcagcagctccaccacgtta
gactgccgcgccactggtgttcccgagccgcggataacctggtttaaaaaccaccgcaaa
atacaacaagaacccggaattattttaggaccaggaagcagcacgctgtttattgaaaga
gtcacagaagaggatgaaggtgtctatcactgcaaagccaccaaccagaaggggtccgtg
gaaagttctgcgtacctcactgttcaaggaacctcagacaagtccaacctggagctcatc
actctgacatgcacctgtgtggctgcaaccctcttctggctcctgttaacgctctttatc
cgaaaactgaaaaggtcttctgaaataaagactgactacctatcaattataatggaccca
gacgaagttcctctggacgagcagtgcgaacgtctcccttatgatgccagcaagtgggag
tttgcccgggagagacttaaactgggcaagtcactcggaagaggggcttttggaaaagtg
gttcaagcttctgcatttggcattaagaaatcacccacatgccggaccgtggctgttaaa
atgctgaaagagggggccacagccagcgagtacaaagctctgatgactgagctcaagatc
ttgacccacattggccaccatctgaatgtagtcaacctgctgggagcctgtaccaagcaa
ggagggcccctgatggtgatcgtcgaatattgcaaatacggaaatctgtccaactacctc
aagagcaaacgggacttattctttctcaacaaggatgcagcattacacgtggagcctaag
aaagaaaaaatggagccagacctggagcaagacaagaaacaaagactagatagtgtcacc
agcagcgagagcttcgcaagctccgggtttcaggaagataaaagtctgagcgatgttgag
gaagaggaggattctgatgatttctacaagcagcccatcactatggaagatctgatttct
tacagttttcaagtggccagaggcatggagtttttgtcttccagaaagtgcattcatcgg
gacctggcagcaagaaatattcttttatctgagaacaatgtggtgaagatctgcgatttt
ggccttgcccgggatatttataagaatcccgattatgtgagaaaaggagatactcgactt
cctctgaagtggatggctcccgaatctatcttcgacaaaatctacagcaccaagagcgac
gtgtggtcttacggagtactgctgtgggaaatcttctccctaggtgggtctccatacccg
ggtgtgcagatggacgaggacttctgcagccgcctgaaggaaggcatgaggatgagggcc
cccgaatacgcaactcctgaaatctatcagatcatgttggactgctggcacaaagaccca
aaagaaaggccaagatttgccgaacttgtggaaaaactaggcgatctgcttcaagcaaat
gtacaacaggacggtaaagactatatcccactaaatgccgtactgacaggaaatagtgcg
tttacatactcatctcctgccttctctgatgacttcttcaaggaagatatttcagctcca
aagtttaattcgggaagttctgataatgtcagatacgtgaatgctttcaatttcatgagc
ctggagagaatcaaaacctttggagaactttcaccaaacaccacctctatctttgatgat
taccaggtggacagtagcactctgctggcctccccctggctgaagcgcttcacctgggct
gagagcaaacccaaggcctccgtgaagattgacttgagagtaaccagtaaaagtaaggag
tcggggctttctgagctcacgcagcctgctttctgccatgccgggtgtgcgcacgtcaac
agaggccggcgcagatttacgtacgacaactcagagctggaaaagaagatttcgtgctgc
tctcctcccccagactacaactcggtggtcttatactccaccccgcctgtctaa
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integrated database retrieval system
