Ursus maritimus (polar bear): 103667043 Help Entry 103667043         CDS       T03271                                  Symbol PSEN2 Name (RefSeq) presenilin-2 isoform X1   KO K04522   presenilin 2 [EC:3.4.23.-] Organism umr  Ursus maritimus (polar bear) Pathway umr04330   Notch signaling pathway umr04722   Neurotrophin signaling pathway umr05010   Alzheimer disease umr05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     103667043 (PSEN2)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     103667043 (PSEN2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     103667043 (PSEN2)    05022 Pathways of neurodegeneration - multiple diseases     103667043 (PSEN2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:umr01002]     103667043 (PSEN2) Peptidases and inhibitors [BR:umr01002]  Aspartic peptidases   Family A22: presenilin family    103667043 (PSEN2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Presenilin Motif Other DBs NCBI-GeneID:  103667043 NCBI-ProteinID:  XP_008693354 UniProt:  A0A384CFV9 LinkDB All DBs Position Unknown AA seq 465 aa AA seqDB search MLTFMASDSEEEVCDERTSLMSAESPPPRCCQEARQGLEDGDNASQWRSQDSEDDLDEDA DRYMCSGVPGQPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLP YGGGREQSLQPAISLSIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKHR CYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKG PLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQE RNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPP LPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTL LLLAVFRKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt atgctcacattcatggcctctgacagtgaggaagaagtgtgtgatgagaggacgtccctg atgtcagccgagagccccccgccgcgctgctgccaggaggcccggcagggcctggaggat ggagacaatgcttcccagtggagaagccaggatagcgaggatgaccttgacgaggacgcg gaccgctacatgtgcagtggggtccccgggcagccgtcaggcctggaagaggagctgacc ctcaaatacggggcgaagcacgtgatcatgctgtttgtgcccgtcaccctgtgcatgatc gtggtggtggccaccatcaagtccgtgcgcttctacacggagaagaacggccagctgccc tatggaggaggcagggagcagagtctgcagcccgccatctccctcagcatctacacacca ttcaccgaggacacgccctccgtgggccagcgcctgctcaactccgtgctcaacacgctc atcatgatcagcgtcatcgtggccatgaccatcttcctggtcgtgctctacaagcaccgc tgctacaagttcattcatggctggttgatcatgtcctccctgatgctgctgttcctcttt acctatatctacctcggggaagtgctcaagacctacaacgtggccatggactaccccacc ctgttcctgactgtctggaactttggcgctgtggggatggtgtgcatccactggaaaggc cccctggtgctgcagcaggcctacctcatcatgatcagcgcgctcatggccttggtcttc atcaagtacctcccggagtggtccgcctgggtcattctgggcgccatctctgtgtatgat ctcgtggctgtgctgtgccccaaagggccgctgaggatgctggtggagactgcccaggag agaaacgagcccatatttcccgccctgatctactcctctgccatggtgtggacggtgggc atggccaagctggacccctcctcccagggagcccttcagctgccctacgaccccgagatg gaagaagactcctatgacagttttggggagccctcgtacccggaagtctttgagcccccc ctgcctggttacccaggggaggagctggaggaagaggaagaaaggggcgtgaagctcggc ctgggggacttcatcttctacagtgtgctggtgggcaaggcggcggccacgggcagcggg gactggaacaccacgctggcatgcttcgtggccatcctcattggtttgtgtctgaccctc ctgctgctggctgtgttcaggaaggcactgcccgccctccccatctccatcacgttcggg ctcatcttctacttctccacggacaacctggtgcgtccgttcatggacaccttggcttct catcagctctacatctga

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