Ursus maritimus (polar bear): 103667783 Help Entry 103667783         CDS       T03271                                  Symbol HKDC1 Name (RefSeq) hexokinase HKDC1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism umr  Ursus maritimus (polar bear) Pathway umr00010   Glycolysis / Gluconeogenesis umr00051   Fructose and mannose metabolism umr00052   Galactose metabolism umr00500   Starch and sucrose metabolism umr00520   Amino sugar and nucleotide sugar metabolism umr00524   Neomycin, kanamycin and gentamicin biosynthesis umr01100   Metabolic pathways umr01200   Carbon metabolism umr01250   Biosynthesis of nucleotide sugars umr04066   HIF-1 signaling pathway umr04910   Insulin signaling pathway umr04930   Type II diabetes mellitus umr04973   Carbohydrate digestion and absorption umr05230   Central carbon metabolism in cancer Module umr_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate umr_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     103667783 (HKDC1)    00051 Fructose and mannose metabolism     103667783 (HKDC1)    00052 Galactose metabolism     103667783 (HKDC1)    00500 Starch and sucrose metabolism     103667783 (HKDC1)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     103667783 (HKDC1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     103667783 (HKDC1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     103667783 (HKDC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103667783 (HKDC1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     103667783 (HKDC1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     103667783 (HKDC1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103667783 (HKDC1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:umr04131]     103667783 (HKDC1) Enzymes [BR:umr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      103667783 (HKDC1) Membrane trafficking [BR:umr04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     103667783 (HKDC1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  103667783 NCBI-ProteinID:  XP_008694190 UniProt:  A0A384CIF1 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MFAVHLMAFYFSKLKEDQIKKVDRFLYDMRLSDETLLDIMTRFQAEMQKGLGKDTNPTAA VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSQEGKRNVQMESQFYPTPNEIIR GNGSELFDYVADCLADFMKTKGLKHKKLPLGLTFSFPCRQTKLEEGILLSWTKKFKARGV QDTDVVSCLTKAMRKHKDIDVDILALVNDTVGTLMTCAYDDPYCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCVNTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL YLGELVRIILLKMAKAGLLFGGKKSSALHTKGKIETRHVAAMEKYKEGLANTREILTDLG LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRVNKKLARLRTTVGMDGTVYKIH PQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLT REQLEDVRGKMRVEFEYGLKKDTHLTATVKMLPTYVCGMPDGTEKGKFLALDLGGTNFRV LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFT FSFPCRQTSIDKGTLIEWTKGFKATDCEGEDMVDMLREAIKRRNEFDLDIVAVVNDTVGT MMTCGHEDPNCEIGLIAGTGSNMCYMEEMRNIELVEGDEGKMCINTEWGGFGDNGCIDDI RTQYDKKVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAV VEKRREDQGLEYLKITVGVDGTLYKLHPHFSRILQETVKELAPRCDVMLMLSEDGSGKGA ALITAVAKRLQQAQKEN NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgtttgcggtacacttgatggcattttacttcagcaagctgaaggaagatcagatcaag aaggtggacaggttcctgtatgacatgcggctctccgatgagacccttttggacatcatg actcgcttccaggctgaaatgcagaagggcctggggaaggacaccaaccccacagccgcc gtgaagatgctgcccacctttgtcagggccattccagatggctcagaaaatggggagttt ctttctctggatcttggagggtccaaatttcgtgtcttgaaggtacaagtctctcaagag gggaaaagaaacgtccagatggagagtcagttctacccaacacccaatgaaattatccga ggcaatggctccgagctgtttgactacgtagctgactgtctggcagatttcatgaagacg aaagggttgaagcataagaaattgccccttggcctaaccttctcttttccgtgcagacag actaagttggaagaggggatcctgctttcatggaccaagaagtttaaggcacggggagtt caagacacagatgtcgtgagttgtctgaccaaagccatgagaaaacacaaggacatagac gtggacatcctggccttggtcaatgacaccgtggggaccctgatgacatgcgcctatgat gatccctactgtgaagttggtgtcatcattggcaccggcaccaacgcgtgttacatggag gacatgagcaacattgacctggtggagggcgatgaggggaggatgtgcgtcaacacggag tggggggccttcggcgacgacggggctctggaagacatccgcaccgagttcgaccgggag ctggacctcggctctctcaaccccgggaagcaactgtttgagaagatgatcagtggcctg tacctgggtgaacttgtcaggatcatcttgctgaagatggccaaggcaggtctcctgttt ggcggcaagaagtcctctgctctccacacaaagggcaagattgaaacacggcacgtggct gccatggagaagtataaggaaggccttgccaatacaagagagatcctgacagatctgggc ctggagccttcggaggccgactgcatcgcggtccagcacgtctgcaccatcgtctccttc cgttcagccaacctgtgtgcagcggccctggcagccatcctgacgcgcctgcgggtgaac aagaagctggcacggctccgcaccacggtgggcatggacggcacggtctacaagatacac cctcaataccccaaacgcctgcacaaagtggtgaggagactggtcccgaactgtgacgtc cgcttcctcttgtcggagagtggcagcaccaagggggctgccatggtgacagcggtggcc tcccgagtgcaggcccagcggaagcagatcgacaaggtgctggctctgttccagctgact cgagagcagcttgaggacgtgcggggcaagatgcgggttgagttcgagtacgggctgaaa aaggacacccacctgacagccacagtcaagatgctgcccacctacgtctgcgggatgcca gatggcacagagaaaggaaagttccttgccctggatctggggggaaccaacttccgggtc ctcctggtaaagatcagaagcggacggaggtcggtgcgaatgtacaacaagatctttgcc atccccttggagatcatgcagggcaccggcgaggagctgttcgatcacatcgtgcagtgc attgctgacttcctggactacatgggcctcaagggagcccagctgcctttgggcttcacg ttctcatttccctgcaggcagacgagcatcgacaagggaacgctcattgagtggaccaaa ggcttcaaggccacggattgtgaaggggaagacatggtggacatgctcagggaagccatc aagaggagaaatgagttcgacctggacatagttgcagttgtgaatgacacagtggggacc atgatgacctgcggccatgaagatcctaattgtgagattggcctgattgcaggaacaggc agcaacatgtgctacatggaggagatgaggaacattgagctggtggaaggggacgaaggg aagatgtgcattaacacagaatggggaggatttggagataatggctgcatagacgacatc cggacccaatatgacaagaaggtggatgaggggtccttgaaccctggcaaacagagatat gagaaaatgaccagtgggatgtacctgggggagattgtgcggcagatcctgattgacctg accaagcagggtctccttttccgtgggcagatttcagagcgtctccggaccaggggcatc tttgaaaccaagttcctgtcccagattgaaagtgatcggctggccctcctccaggtcagg aggatcctgcagcagctcggcctggacagcacatgtgaggacagcattgtggtgaaggag gtgtgcggagctgtgtcccggcgggcggcccagctctgcggcgctggcctggctgctgtc gtggagaagaggagggaagaccaggggctggagtacctgaagatcaccgtgggagtggat ggcacgctgtacaagctgcacccgcacttttctcggatattgcaggaaactgtgaaagag ctagctcctcgatgtgatgtgatgctcatgctgtctgaagatgggagtggaaagggagct gctctgatcactgctgtggccaagaggttacagcaggcccagaaggagaactag

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