Ursus maritimus (polar bear): 103667958
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Entry
103667958 CDS
T03271
Symbol
IDE
Name
(RefSeq) insulin-degrading enzyme isoform X1
KO
K01408
insulysin [EC:
3.4.24.56
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr03266
Virion - Herpesvirus
umr05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03266 Virion - Herpesvirus
103667958 (IDE)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103667958 (IDE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
umr01002
]
103667958 (IDE)
Enzymes [BR:
umr01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.56 insulysin
103667958 (IDE)
Peptidases and inhibitors [BR:
umr01002
]
Metallo peptidases
Family M16: pitrilysin family
103667958 (IDE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Peptidase_M16_M
Peptidase_M16_C
Peptidase_M16
PqqF-like_C_4
Tn916-Xis
PqqF_C_3
Motif
Other DBs
NCBI-GeneID:
103667958
NCBI-ProteinID:
XP_040480072
UniProt:
A0A8M1FDV0
LinkDB
All DBs
Position
Unknown
AA seq
1019 aa
AA seq
DB search
MRYRLAWLLHFARPSTFRSVLGSRLLSPERFCGFQEKTYSKMNNPAIKRLGNHIIKSPED
KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQE
LLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
VSKSFEGKTDRTEEWYGTQYKQEAVPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILSL
EKEATPYPSLIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL
SAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
NT seq
3060 nt
NT seq
+upstream
nt +downstream
nt
atgcggtaccggctagcgtggctgctgcacttcgcgcggcccagcaccttccgctcggtt
ctcggctcccgcctgctgtccccggagcgcttctgtggtttccaagagaagacttacagc
aagatgaataatccagctatcaagagactaggaaatcacattatcaagtctcccgaagac
aagcgagaataccgtgggctagagctggccaatggtatcaaagtacttctcatcagtgat
ccgaccacagataagtcatcagcagcacttgatgtgcacataggttcattgtcagatcct
ccaaatattgctggcttaagtcatttttgtgaacatatgctatttttgggaacaaagaaa
taccctaaagaaaatgaatacagccagtttctcagtgagcatgcaggaagttcaaatgcc
tttactagtggagaacataccaattactattttgatgtttcccacgaacacctagaaggt
gccctagacaggtttgcacaatttttcctgtgccccttatttgatgagagttgcaaagac
agagaggtgaatgcggttgattcagagcatgagaagaatgtaatgaacgatgcctggaga
ctcttccagttggaaaaagctacggggaatcccaaacaccccttcagcaaatttgggaca
ggtaacaaatatactttagagactagaccaaaccaagaaggcattgatgtaagacaagag
ctactgaaattccattctacttattattcatccaacttaatggctatttgtgtgctaggt
cgagaatctttagacgacttgactaatctggtggtaaagttattttctgaagttgagaac
aaaaatgtcccactgccagaatttcctgaacaccctttccaagaagaacatcttaaacaa
ctttacaagatagtacccattaaggatattaggaatctatatgtgacatttcccatacct
gaccttcagaaatactacaaatcaaatcctggccattatcttggtcatctcattggtcat
gaaggtcctggaagtctcttatcagaacttaaatcaaagggttgggtaaatactctagtt
ggtggacagaaggagggagcccgaggttttatgttttttatcattaatgtggacctgact
gaggaaggattattacacgttgaagatataattttgcacatgtttcaatacattcagaag
ctacgtgcagaaggacctcaagaatgggttttccaagagtgcaaggacttgaatgctgtt
gcgtttaggtttaaagataaagagaggccacggggctatacctctaagattgcaggaata
ttgcattattatcccctggaagaagtgctcacagctgaatatttactggaagaatttaga
cctgacttaatagagatggttctcgataaactcagaccagaaaatgtccgggttgcaata
gtttccaagtcctttgaaggaaaaactgaccgcacagaagagtggtacggaacccagtac
aagcaagaagctgtaccagatgaagtcattaagaaatggcaaaatgctgacctgaatggg
aaatttaaacttccaacgaagaatgaatttattcctacaaattttgagattttatcatta
gaaaaagaagcgacaccatacccttctcttattaaggatacagcaatgagcaaactctgg
ttcaaacaagatgataagtttttcttgccaaaggcttgtctcaactttgaatttttcagc
ccatttgcttatgtggaccccttgcactgtaacatggcctatttgtaccttgagctcctc
aaagactcactcaacgagtatgcatatgcagcagagctagcaggcttgagctatgacctc
caaaataccatctatgggatgtatctttcggtgaaaggttacaatgacaagcagccgatt
ttgctaaagaagattattgagaaaatggctacctttgagattgatgaaaaaagatttgaa
attatcaaagaggcatatatgcgctctcttaacaatttccgagccgagcagcctcaccag
cacgccatgtactacctccgcctgctgatgacggaagtggcctggacgaaggatgaatta
aaggaagccctggatgatgtcacccttcctcgccttaaggccttcatacctcagctcctg
tcacggctgcacatcgaagcccttctccatggaaacataacaaagcaggctgcgctagga
attatgcagatggttgaagacaccctcattgaacatgctcatacaaaacctcttcttcca
agtcagctggttcggtatagagaagttcagctccctgacagaggatggttcgtgtatcag
cagaggaatgaagttcacaataactgtggcatcgagatatactaccagacagacatgcag
agcacctccgagaatatgtttctagagctcttctgtcaaatcatctccgaaccttgcttc
aataccctgcgtaccaaggagcagctgggctatatcgtcttcagcgggcctcgtcgagcc
aatggcatacagggcttacgattcatcatccagtcagaaaagccacctcactacctagag
agcagagtggaagctttcctaatcaccatggagaagtccatagaggacatgacagaagag
gcttttcaaaaacacattcaagctttagccatccgccgactagacaaaccaaagaaacta
tccgcagagtgtgctaaatactggggggaaatcatctctcagcaatacaattttgacaga
gacaatacagaagttgcatatttaaagacacttaccaaggaagatatcatcaaattctac
aaggaaatgttggcagtagatgccccaaggagacataaggtatcagtccatgttcttgcc
agagaaatggattcttgtcctgtggttggagagttcccatgtcaaaatgatataaatttg
tcacaagcaccagccctgccacaacctgaagtgattcagaacatgactgagttcaagcgt
ggtttgccactgtttccccttgtgaaaccacatattaacttcatggctgcaaaactctga
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