Ursus maritimus (polar bear): 103668004 Help Entry 103668004         CDS       T03271                                  Symbol HK1 Name (RefSeq) hexokinase-1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism umr  Ursus maritimus (polar bear) Pathway umr00010   Glycolysis / Gluconeogenesis umr00051   Fructose and mannose metabolism umr00052   Galactose metabolism umr00500   Starch and sucrose metabolism umr00520   Amino sugar and nucleotide sugar metabolism umr00524   Neomycin, kanamycin and gentamicin biosynthesis umr01100   Metabolic pathways umr01200   Carbon metabolism umr01250   Biosynthesis of nucleotide sugars umr04066   HIF-1 signaling pathway umr04910   Insulin signaling pathway umr04930   Type II diabetes mellitus umr04973   Carbohydrate digestion and absorption umr05230   Central carbon metabolism in cancer Module umr_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate umr_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     103668004 (HK1)    00051 Fructose and mannose metabolism     103668004 (HK1)    00052 Galactose metabolism     103668004 (HK1)    00500 Starch and sucrose metabolism     103668004 (HK1)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     103668004 (HK1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     103668004 (HK1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     103668004 (HK1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     103668004 (HK1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     103668004 (HK1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     103668004 (HK1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     103668004 (HK1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:umr04131]     103668004 (HK1) Enzymes [BR:umr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      103668004 (HK1) Membrane trafficking [BR:umr04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     103668004 (HK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Sec23_helical UvrD-helicase Motif Other DBs NCBI-GeneID:  103668004 NCBI-ProteinID:  XP_040479978 UniProt:  A0A8M1F977 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFKKEMKNGLSRDFNPTAT VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQNVHMESEIYDTPENIVH GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEGILITWTKKFKASGV EGMDVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME ELRHIDLVEGDEGRMCVNTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM YLGELVRLILVKMAKESLLFEGRITPELLTRGKFKTSDVSAIEKNKEGLHNAKEILTRLG VEPSDDDCISVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFRLT KDMLLEVKKRMRAEMDMGLRKQTHEKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPKMPLGF TFSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLREAIKRREEFDLDVVAVVNDTVG TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVETLEGNDGRMCINMEWGAFGDNGCLDD IRTLYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG IFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA VVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMYQTVKELSPKCNVSFLLSEDGSGKG AALITAVGVRLREETSS NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgccgcgcagctcctggcctattacttcaccgagctgaaggatgaccaagtcaaa aagattgacaagtatctctatgccatgcggctctctgatgaaaccctgatagatatcatg actcgtttcaagaaggagatgaagaatggcctctcccgggattttaatccaacagccaca gtcaagatgttgccaacgtttgtaaggtccattcctgatggttcagaaaagggagatttc attgccctggatcttggcgggtcttcctttcgaattctgagggtacaagtgaatcacgag caaaaccagaatgttcacatggagtccgagatttatgacaccccggagaacatcgtgcat ggcagtggaagccagctttttgatcacgtggccgagtgcctgggagacttcatggagaaa aaaaaaatcaaggacaagaaattacctgtgggattcacgttttctttcccctgtcggcag tccaaaatagacgagggcatcctgataacctggacaaagaaatttaaagcgagcggagtg gagggaatggatgtggtgaagttgcttaacaaagccattaagaagcgcggggactacgac gccaacattgtggccgtggtgaacgacacggtggggaccatgatgacctgtggctacgat gaccagcagtgtgaagtcggcctcatcatcggcaccggcaccaacgcctgctacatggag gagctgaggcacattgacctggtggagggcgatgaggggaggatgtgcgtcaacacggag tggggggccttcggcgacgacgggtccctggaagacatccgcaccgagttcgaccgggag atagaccgtggctctctcaaccccgggaagcagctgtttgagaagatggtcagtggcatg tacttgggggagctggtgcgactgatcctggtcaagatggccaaggagagcctcttgttt gaagggcggatcaccccggagctgctcaccagggggaagttcaagaccagcgacgtgtca gccattgagaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga gtggagccatccgatgacgactgtatttcagtccagcacgtgtgtaccattgtctcattt cgctcggccaacctggtggctgcaacgctgggcgccatcttgaaccgccttcgagataac aagggcacacccaggctgcggaccacggttggtgtcgacgggtctctttacaagacgcac ccacagtattcccggcgtttccacaagactctgaggcgcttggtgcccgactccgatgtg cgcttcctcctctcggagagcggcagtggcaagggggcggccatggtcacggcggtggcc taccgcctggcggagcagcaccggcagatagaggagaccctggcccacttccgcctcacc aaggacatgctgctggaggtgaagaagaggatgcgggccgagatggatatgggcctgagg aagcagacacacgagaaggccgtggtcaagatgctgccctcctttgtccggagcactcca gacgggaccgagcatggtgacttcttggcccttgatcttggaggaacaaatttccgtgtc ctgctggtgaaaatccgcagtgggaaaaagagaacggtggaaatgcacaacaagatctat gccattcccattgaaatcatgcagggcactggggaagagctgtttgaccacatcgtctcc tgcatctctgacttcctggactacatggggatcaaaggccccaaaatgcctctgggcttc acgttctccttcccctgcaagcagacgagcctggatgcgggaatcttgatcacctggacc aagggttttaaggcaaccgactgcgtggggcacgacgtagcaaccttactaagggaagcg ataaaacggagagaggaattcgacctggacgtggtggctgtggtcaatgacacggtgggc accatgatgacctgtgcttacgaggagcctacctgcgaggttggactcattgtagggacc ggcagcaacgcctgctacatggaggaaatgaagaatgtcgagacgctggaggggaatgac gggcgcatgtgtatcaacatggagtggggtgcctttggggacaacgggtgtctagatgat atcagaacactctatgacagactggtggatgaatattctctaaacgctgggaaacaaagg tacgagaagatgattagcggtatgtacctgggtgagatcgtccgcaacatcttgatcgac ttcaccaagaagggcttcctcttccgagggcagatctctgagacgctgaagacccggggc atctttcagaccaaatacctttcccagattgagagtgaccgattagcgctgctccaggtc cgggccatcctccagcagctgggcctgaacagcacctgtgacgacagtatcctggtcaag actgtgtgcggggtggtgtccaagagggccgcgcagctgtgtggtgcgggcatggctgcc gtggtggataagatccgagagaacagagggctggaccacctcaacgtgactgtgggggtg gacggaacactctacaagcttcatccgcacttctccagaatcatgtaccaaaccgtgaag gaactgtcaccaaaatgtaacgtgtccttcctcctgtccgaagacggtagcggcaagggg gccgccctcatcacggcggtgggcgtccggctccgggaagagacgagcagctaa

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